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Curr Med Res Opin ; 30(6): 1197-9, 2014 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-24640937

RESUMO

Currently, vitamin D deficiency and obesity are pandemic diseases and they are associated with cardiovascular (CV) disease, metabolic syndrome and type 2 diabetes mellitus (T2DM) and other diseases. Concentrations of 25-hydroxyvitamin D (25(OH)D) (25D) are considered as the best indicator of total body vitamin D stores. An association between reduced circulating 25D concentrations and obesity is well known, but the mechanisms are not totally clear. The role of vitamin D supplementation is still uncertain and prospective interventions will establish its influence, if any, in the treatment of obesity. Vitamin D deficiency is associated with the presence of a cardiometabolic risk profile in the obese. Future trials may establish a role for Vitamin D supplementation in individuals at increased CV risk.


Assuntos
Obesidade/sangue , Deficiência de Vitamina D/sangue , Vitamina D/análogos & derivados , Doenças Cardiovasculares/sangue , Diabetes Mellitus Tipo 2/sangue , Humanos , Síndrome Metabólica/sangue , Vitamina D/sangue
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