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Métodos Terapêuticos e Terapias MTCI
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2.
J Biomed Mater Res ; 21(7): 913-20, 1987 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-3038919

RESUMO

The adherence of Streptococcus mutans OMZ-176 to six implant materials (poly-crystal alumina, single-crystal alumina, titanium alloy, cobalt-chromium-molybdenum alloy, hydroxyapatite, and heat-curing polymethylmethacrylate resin) was studied in vitro. The change of free energy, which corresponds to the adherence process, was also evaluated for hydrophobic interaction. Adherence of S. mutans to poly-crystal alumina was lower than adherence to other materials. The adherence of S. mutans to the test materials was highly correlated with the change of free energy, which suggests that hydrophobic interaction plays an important role in the adherence of S. mutans to the implant materials.


Assuntos
Aderência Bacteriana , Materiais Biocompatíveis , Próteses e Implantes , Streptococcus mutans/fisiologia , Ligas , Óxido de Alumínio , Ligas de Cromo , Cobalto , Durapatita , Hidroxiapatitas , Metilmetacrilatos , Molibdênio , Propriedades de Superfície , Termodinâmica , Titânio
4.
J Antibiot (Tokyo) ; 36(10): 1380-6, 1983 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-6580289

RESUMO

The effect of cefmetazole on the growth together with the release of cellular lipoteichoic acid from cefazolin-resistant strains of Staphylococcus aureus was compared with that of cefazolin, cefotiam, cefoxitin and cefuroxime. Bacteriolytic actions were measured by turbidity and bactericidal actions were followed by viable cell count. Release of cellular lipoteichoic acid was measured by the radioactivity in the supernatant of the cultures. Cefmetazole exerted more potent effects on the bacterial growth and induced more marked release of cellular lipoteichoic acid from resistant strains as compared with other beta-lactams.


Assuntos
Antibacterianos/farmacologia , Cefamicinas/farmacologia , Lipopolissacarídeos , Ácidos Fosfatídicos/metabolismo , Staphylococcus aureus/metabolismo , Ácidos Teicoicos/metabolismo , Antibacterianos/toxicidade , Cefmetazol , Cefamicinas/toxicidade , Glicerol/metabolismo , Cinética , Testes de Sensibilidade Microbiana , Staphylococcus aureus/efeitos dos fármacos , Relação Estrutura-Atividade
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