1.
Clin Transl Med
; 14(2): e1569, 2024 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38356432
2.
Fitoterapia
; 147: 104774, 2020 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33152461
RESUMO
Nine new diterpenoids, Rubellacrns A - I (1-9), including five isopimaranes (1-4, 9), four pimaranes (5-8), together with five known isopimarane analogues (10-14), were isolated from Callicarpa rubella. The structures of these compounds were unambiguously established by HR-ESIMS and NMR spectroscopic data, the absolute configurations of compounds 5 and 9 were determined by ECD. All the isolated compounds were tested for their anti-inflammatory effects and compounds 2 and 11-14 showed NLRP3-inflammasome inhibitory activity with IC50 values ranging from 7.02 to 14.38 µM.