RESUMO
Clinical manifestations accompanying neurological diseases are diverse and affect multiple organs. Nutritional status of patients with certain neurological diseases such as stroke, Alzheimer's disease, Parkinson's disease, Epilepsy and Multiple Sclerosis can be altered because of symptoms associated with disease course, including certain micronutrient deficiency (folic acid, zinc, vitamin B6 and B12, vitamin D, vitamin E and vitamin C), changes in energy expenditure, intake decreased, gastrointestinal disorders and dysfunction of the bone mass. Also, we have to take in account other factors as: advanced age, multiple co morbidities, polypharmacy, the use of herbal products, social habits, diet and pharmacological treatments effect. An assessment of the factors related to neurological treatment that cause alterations in metabolic and nutritional status was performed: side effects of anti-Parkinson drugs, antiepileptic drugs, and multiple sclerosis drugs; drug-nutrient interactions; and nutrient-drug interactions.
Assuntos
Doenças do Sistema Nervoso/tratamento farmacológico , Estado Nutricional , Deficiência de Vitaminas/complicações , Deficiência de Vitaminas/terapia , Interações Medicamentosas , Humanos , Doenças do Sistema Nervoso/complicaçõesRESUMO
Las manifestaciones clínicas que acompañan a las enfermedades neurológicas son muy variadas, afectando a múltiples órganos. Los pacientes con ciertas patologías neurológicas como son el ictus, la enfermedad de Alzheimer, Parkinson, Epilepsia y Esclerosis Múltiple pueden ver su estado nutricional alterado a causa de determinados síntomas relacionados con el curso de la enfermedad, como el déficit de determinados micronutrientes (ácido fólico, zinc, vitaminas B6 y B12, vitamina D, vitaminas E y vitamina C), alteraciones del gasto energético, disminución de la ingesta, alteraciones gastrointestinales y disfunción de la masa ósea. A estas circunstancias, hay que añadir el efecto de otros factores: edad avanzada, múltiples comorbilidades, polifarmacia, la utilización de fitoterapia, hábitos sociales, la dieta y el efecto de los tratamientos farmacológicos (AU)
Clinical manifestations accompanying neurological diseases are diverse and affect multiple organs. Nutritional status of patients with certain neurological diseases such as stroke, Alzheimers disease, Parkinsons disease, Epilepsy and Multiple Sclerosis can be altered because of symptoms associated with disease course, including certain micronutrient deficiency (folic acid, zinc, vitamin B6 and B12, vitamin D, vitamin E and vitamin C), changes in energy expenditure, intake decreased, gastrointestinal disorders and dysfunction of the bone mass. Also, we have to take in account other factors as: advanced age, multiple co morbidities, polypharmacy, the use of herbal products, social habits, diet and pharmacological treatments effect. An assessment of the factors related to neurological treatment that cause alterations in metabolic and nutritional status was performed: side effects of anti-Parkinson drugs, antiepileptic drugs, and multiple sclerosis drugs; drugnutrient interactions; and nutrient-drug interactions (AU)