Assuntos
Dermatologia/história , Lasers/história , História do Século XX , Humanos , Fotocoagulação a Laser/história , Fotocoagulação a Laser/instrumentação , Terapia a Laser/história , Terapia a Laser/instrumentação , Lasers/classificação , Fototerapia/história , Dermatopatias/cirurgia , Dermatopatias/terapiaRESUMO
The Q-switched ruby laser was used to treat 101 amateur and 62 professional tattoos in 80 patients over a period of 22 months. Using a 5- to 8-mm spot size and energy fluences of 2-4 joules/cm2, an average of three retreatments resulted in complete pigment removal in four, nearly complete pigment removal in 84, significant pigment removal in 11, and minimal pigment removal in two amateur tattoos. Using identical parameters for professional tattoos, there was complete pigment removal in two, nearly complete pigment removal in five, significant pigment removal in 18, minimal pigment removal in 25, and very little pigment removal in 12. Professional tattoos with red, yellow, and green pigments faded, but required multiple retreatments. While transient hypopigmentation occurred in many patients, skin texture and hair growth returned to normal in all cases and no hypertrophic scarring was seen.
Assuntos
Terapia a Laser , Tatuagem , Adolescente , Adulto , Idoso , Anestesia Local , Procedimentos Cirúrgicos Dermatológicos , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Cuidados Pós-Operatórios , Pele/patologiaRESUMO
Eight topical agents in current use were studied for their effects on wound contraction and rate of reepithelialization of full-thickness excisions using a porcine animal model. The following agents were applied daily for a period of 27 days: scarlet red ointment, benzoyl peroxide lotion, bacitracin ointment, silver sulfadiazine cream, aloe vera gel, tretinoin cream, capsaicin cream, and mupirocin ointment. The rate of reepithelialization was significantly enhanced by treatment with capsaicin, bacitracin, silver sulfadiazine, and scarlet red, and was markedly retarded by treatment with tretinoin. Wound contraction was significantly retarded by mupirocin, bacitracin, and silver sulfadizine. Knowledge of the effects of topical agents on various aspects of healing allows the clinician to choose the most appropriate material to use in a given clinical situation to optimize the healing process and produce the best final result.
Assuntos
Fármacos Dermatológicos/farmacologia , Cicatrização/efeitos dos fármacos , Administração Tópica , Aloe , Animais , Antibacterianos/farmacologia , Compostos Azo/farmacocinética , Bacitracina/farmacocinética , Peróxido de Benzoíla/farmacocinética , Capsaicina/farmacologia , Celulose/farmacocinética , Fármacos Dermatológicos/administração & dosagem , Ácidos Graxos/farmacologia , Glicerol/farmacocinética , Mupirocina , Fosfatos/farmacocinética , Extratos Vegetais/farmacocinética , Plantas Medicinais , Propilenoglicóis/farmacocinética , Sulfadiazina de Prata/farmacocinética , Pele/patologia , Suínos , Porco Miniatura , Tretinoína/farmacocinéticaRESUMO
A case of localized calcinosis cutis of the hands and fingers is described in an oil field worker with normal serum calcium and phosphorus levels. The proposed mechanism consists of percutaneous penetration and subsequent deposition of calcium from the daily exposure to industrial drilling fluids containing calcium salts.