RESUMO
Recently the incidence of Group B streptococcus (Streptococcus agalactiae) infection has been increased in nonpregnant adults, especially including the elderly and those with underlying diseases. One year ago, a 72-year-old diabetic woman underwent both total knee replacement and then received intermittently acupuncture due to both knee pain. Five days ago, she developed painful swelling on right knee joint. The synovial fluid showed leukocytosis (WBC 8,200/mm3), she was diagnosed as prosthetic joint infection, and treated with cefazolin. Her condition was rapidly aggravated despite of antibiotics therapy, open debridement and drainage was performed. But she expired due to sepsis. Both blood and synovial fluid culture yielded S. agalactiae. We reported a case of prosthetic knee joint infection caused by S. agalactiae.
Assuntos
Adulto , Idoso , Feminino , Humanos , Acupuntura , Antibacterianos , Artroplastia do Joelho , Cefazolina , Desbridamento , Drenagem , Incidência , Articulações , Joelho , Articulação do Joelho , Leucocitose , Sepse , Streptococcus , Streptococcus agalactiae , Líquido SinovialRESUMO
The neuroleptic malignant syndrome (NMS), a serious and potentially fatal complication, has been reported to occur in some patients with administration od neuroleptic medications. Its major manifestations are muscular rigidity, autonomic instability, altered consciousness, and hyperthermia, often accompanied by raised creatine kinase (CK) and leukocytosis. Manifestations of NMS are attributed to dopamine receptor blockade in the striatum, increasing thermogenesis, and in the hypothalamus, impaired heat dissipation. Owing to the potential lethality of NMS, the early diagnosis is important. The authors report two survived patients with the NMS who were treated by generalized supportive care and drug therapy.