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1.
Environ Sci Pollut Res Int ; 30(47): 104477-104488, 2023 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-37702867

RESUMO

China's Paris Agreement Pledge and recent introduction of an Emissions Trading Scheme have created a need for information on where it makes the most economic sense to use different sources of energy. With lower carbon dioxide emissions, natural gas and liquefied petroleum gas provide cleaner sources of energy relative to coal. Although it is practically crucial to investigate the use of these two sources, empirical studies are limited due to lack of data. To fill the research gap, this paper studies the efficiency of natural gas and liquefied petroleum gas sector in China by using data from 24 major province-level divisions over the years 2006-2015. Efficiency is defined as the utility's ability to produce the highest output given fixed inputs. We find that: (1) GDP per capita and high customer density are associated with higher levels of efficiency and (2) utilities that serve higher proportions of households (as opposed to industry and firms) are associated with lower levels of efficiency. Policy makers can use this information to address China's energy needs due to rapid urbanization while also pursuing Paris Agreement goals.


Assuntos
Gás Natural , Petróleo , Carvão Mineral , Urbanização , China , Desenvolvimento Econômico , Dióxido de Carbono/análise
2.
Genome Biol ; 23(1): 233, 2022 11 07.
Artigo em Inglês | MEDLINE | ID: mdl-36345039

RESUMO

BACKGROUND: Regulation of gene expression plays an essential role in controlling the phenotypes of plants. Brassica napus (B. napus) is an important source for the vegetable oil in the world, and the seed oil content is an important trait of B. napus. RESULTS: We perform a comprehensive analysis of the transcriptional variability in the seeds of B. napus at two developmental stages, 20 and 40 days after flowering (DAF). We detect 53,759 and 53,550 independent expression quantitative trait loci (eQTLs) for 79,605 and 76,713 expressed genes at 20 and 40 DAF, respectively. Among them, the local eQTLs are mapped to the adjacent genes more frequently. The adjacent gene pairs are regulated by local eQTLs with the same open chromatin state and show a stronger mode of expression piggybacking. Inter-subgenomic analysis indicates that there is a feedback regulation for the homoeologous gene pairs to maintain partial expression dosage. We also identify 141 eQTL hotspots and find that hotspot87-88 co-localizes with a QTL for the seed oil content. To further resolve the regulatory network of this eQTL hotspot, we construct the XGBoost model using 856 RNA-seq datasets and the Basenji model using 59 ATAC-seq datasets. Using these two models, we predict the mechanisms affecting the seed oil content regulated by hotspot87-88 and experimentally validate that the transcription factors, NAC13 and SCL31, positively regulate the seed oil content. CONCLUSIONS: We comprehensively characterize the gene regulatory features in the seeds of B. napus and reveal the gene networks regulating the seed oil content of B. napus.


Assuntos
Brassica napus , Brassica napus/genética , Brassica napus/metabolismo , Redes Reguladoras de Genes , Sementes/genética , Sementes/metabolismo , Locos de Características Quantitativas , Óleos de Plantas/metabolismo
3.
Neurosciences (Riyadh) ; 19(2): 130-3, 2014 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-24739411

RESUMO

Traditional Chinese medicine (TCM) comprises a range of traditional medical practices that originate in China, including herbal medicine as a major therapy. Through its 4 natures; namely, cold, hot, warm, and cool, herbal medicine may regulate sympathetic nerves and basal metabolic rate and affect the CNS and the endocrine system. Heat stroke is a severely life-threatening heat-related illness that is most commonly seen during summer heat waves and high environmental temperatures. The intake of medications or toxins is considered one of the risk factors leading to heat stroke, as they may affect body thermoregulation. We report a case of heat stroke that was associated with herbal therapy with TCM. This case highlights the importance of paying more attention to unidentified folk prescriptions in the use of TCM.


Assuntos
Golpe de Calor/induzido quimicamente , Temperatura Alta/efeitos adversos , Medicina Tradicional Chinesa/efeitos adversos , Edema Encefálico/diagnóstico , Edema Encefálico/etiologia , Paralisia Facial/terapia , Feminino , Golpe de Calor/complicações , Golpe de Calor/diagnóstico , Humanos , Imageamento por Ressonância Magnética , Pessoa de Meia-Idade
4.
FEBS Lett ; 550(1-3): 124-34, 2003 Aug 28.
Artigo em Inglês | MEDLINE | ID: mdl-12935898

RESUMO

A cDNA library of male Chinese seahorse (Hippocampus kuda Bleeker) was constructed to investigate the molecular profile of seahorse as one of the most famous traditional Chinese medicine materials, and to reveal immunological and physiological mechanisms of seahorse as one of the most primitive vertebrates at molecular level. A total of 3372 expressed sequence tags (ESTs) consisting of 1911 unique genes (345 clusters and 1566 singletons) were examined in the present study. Identification of the genes related to immune system, paternal brooding and physiological regulation provides not only valuable insights into the molecular mechanism of immune system in teleost fish but also plausible explanations for pharmacological activities of Chinese seahorse. Furthermore, the occurrence of high prevalent C-type lectins suggested that a lectin-complement pathway might exert a more dominant function in the innate immune system of teleost than mammal. Carbohydrate recognition domain (CRD) without a collagen-like region in the lectins of seahorse was likely an ancient characteristic of lectins similar to invertebrates.


Assuntos
Etiquetas de Sequências Expressas , Medicina Tradicional Chinesa , Proteínas/genética , Smegmamorpha/genética , Sequência de Aminoácidos , Animais , DNA Complementar , Sistema Imunitário/fisiologia , Imunidade Inata/genética , Lectinas/genética , Masculino , Dados de Sequência Molecular , Proteínas/classificação , Reprodução/genética , Homologia de Sequência de Aminoácidos
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