RESUMO
OBJECTIVE: To study the chemical constituents of Vitex trifolia. METHODS: Chromatography and spectroscopic analysis were employed to isolate and elucidate the chemical constituents in the plant. RESULTS: Five triterpenoids were obtained and identified as ursolic acid (I),2alpha,3alpha-dihydroxyurs-12-en-28-oic acid (II), betulinic acid (11), taraxerol (IV), 2alpha,3beta, 19-trihydroxyurs-12-en-28-oic acid (V). CONCLUSION: Compounds 1-5 are isolated from this plant for the first time.
Assuntos
Plantas Medicinais/química , Triterpenos/isolamento & purificação , Vitex/química , Etanol/química , Estrutura Molecular , Ácido Oleanólico/análogos & derivados , Ácido Oleanólico/química , Ácido Oleanólico/isolamento & purificação , Triterpenos Pentacíclicos , Espectrofotometria Infravermelho , Espectrofotometria Ultravioleta , Triterpenos/química , Ácido Betulínico , Ácido UrsólicoRESUMO
OBJECTIVE: To study the chemical constituents of the root of Rhaponticum uniflorum. METHOD: Separation and purification were performed on silica gel and Sephadex LH-20 column chromatography. Their structure were elucidated on the basis of physicochemical and spectral analysis. RESULT: Five triterpenoid compounds were isolated and identified as ursolic acid (1), 3-oxo-19alpha-hydroxyurs-12-en-28-oic acid (2), pomolic acid (3), arjunic acid (4) and tormentic acid (5), respectively. CONCLUSION: Compounds 1 approximately 5 were isolated from the genus Rhaponticum for the first time.