1.
Org Lett
; 12(10): 2274-7, 2010 May 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20405874
RESUMO
A new label-free continuous assay with the ensemble of compound 1 and Arg(6) for trypsin and inhibitor screening was successfully developed by taking advantage of the aggregation-induced emission feature of tetraphenylethene compounds. Both CLSM and DLS studies confirm the formation of the aggregation complex of compound 1 and Arg(6) and disassembly after further addition of trypsin.