[Investigation on folic acid supplementation status among Chinese women in the first trimester of pregnancy].

OBJECTIVE: To investigate folic acid (FA) supplementation status among Chinese rural reproductive women in their early pregnancy, and to provide evidence for the evaluation of FA supplementation project from national basic public health services. METHODS: The data on intake status of FA supplementation from "National Free Preconception Health Examination Project (NFPHEP)" database between January 1, 2010 and December 31, 2012 was used and analyzed.A total of 902 270 women who achieved follow-up during early pregnancy from 220 pilot counties of 31 provinces were recruited. RESULTS: From 2010 to 2012, the rate of FA intake among women recuited were 73.58% (134 131/182 289), 75.88% (329 288/433 970) and 76.53% (218 896/286 011), respectively, which increased year by year (χtrend(2)=13 371.8, P<0.001). Among 682 315 women who took FA, 350 738(51.40%) women began to take FA 3 months before amenorrhea; 130 683 (19.15%) women began to take FA 1-2 months before amenorrhea, and 200 894 (29.44%) began to take FA after amenorrhea.Among 682 315 women who took FA, 645 310 (94.58%) women took it regularly, and 342 418 (50.18%) women took FA in a standardized way. CONCLUSIONS: The status of FA intake among Chinese rural women in the first trimester of pregnancy was good, and 75.62% (682 315/902 270) of them took FA.It is also important for basic public health services to improve the rate of FA intake and increase the rate of taking FA in a standardized way in Chinese rural pregnant women.

[Study on experimental parameters for diagnosing ganyang huafeng syndrome of cerebral infarction].

One hundred patients with cerebral infarction were observed, the results showed that Ganyang Huafeng Syndrome (GYHFS) was the major syndrome of acute cerebral infarction which was accounted for 60% and Qiyin Liangxu Syndrome (QYLXS), Qixu Xueyu Syndrome (QXXYS) were mainly observed at convalescent stage of this disease which was accounted for 37.78% and 31.11% respectively. This study chose plasma norepinephrine (NE), epinephrne (E), thromboxane B2(TXB2), 6-keto-PGF1 alpha, cortisol (F) and serum triiodothyroidoglobulin (T3) as the monitoring parameters, and the results showed that the increase of plasma NE,F,TXB2, the decrease of serum T3 could be considered as the comprehensive experimental parameters for diagnosing GYHFS of cerebral infarction.

[Relationship between three extracting factors and extracting rate and stability of chlorogenic acid in the refining process of flos Lonicerae].

Content determination of chlorogenic acid in the extract of Flos Lonicerae by reversed-phase HPLC has proved that relatively long time boiling in weak acid conditions is beneficial to increasing the extracting rate of the acid. Also, verifying experiments have shown that chlorogenic acid remains stable in the above-said conditions.