RESUMO
<p><b>OBJECTIVE</b>To study and analyze the antibacterial effects of different extracts from Radix Isatis.</p><p><b>METHODS</b>Staphylococcus aureus was used as the studied object in the experiment. Antibacterial effects of extracts from Radix Isatis were observed by thermocalrimetry on Staphylococcus aureus, together with common pharmacological experiments.</p><p><b>RESULTS</b>The total extract, ethyl acetate (EtOAc) extract, n-butylalcohol (nBuOH) extract, chloroform (CHCl(3)) extract and petroleum (P.E.) extract had antiviral effects to some extent while the residue after extracting had no antibacterial activity. The potency of antiviral activity among them was as follows: nBuOH extract > EtOAc extract > CHCl(3) extract > total extract > P.E. extract.</p><p><b>CONCLUSION</b>The antibacteriall effects of Radix Isatis were not limited to any active portion, showing that Radix Isatis exerts its antibacterial effects by cooperation of different active fractions in varied ways.</p>
Assuntos
Antibacterianos , Farmacologia , Calorimetria , Isatis , Testes de Sensibilidade Microbiana , Extratos Vegetais , Farmacologia , Raízes de Plantas , Staphylococcus aureusRESUMO
The adverse drug reaction (ADR) of traditional Chinese medicine (TCM) has been concerned nowadays. Some bans were published to limit their use abroad. There wasn't a feasible criterion to reply to the ADR of TCM yet in China. The ADR of 6 kinds of typical TCM which state attached importance to was chosen to discuss. Based on the retrospect investigation, the objectivity of ADR was explored in this study.