1.
Am J Chin Med
; 16(3-4): 139-44, 1988.
Artigo
em Inglês
| MEDLINE
| ID: mdl-3245534
RESUMO
The promyelocytic cell line HL-60 could be induced to differentiate into morphologically and functionally mature monocytoid cells (up to 20%) following exposure to the Chinese herb Clerodendron Fragrans (1 mg/ml). This effect was time dependent and appeared to work synergistically with interferon-r in this promotion of differentiation. Our study suggests that Clerodendron Fragrans has potential therapeutic value for the treatment of certain acute myelocytic leukemia putatively caused by a block in the myeloid differentiation process.