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Medicinas Complementares
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1.
Int J Pharm ; 623: 121913, 2022 Jul 25.
Artigo em Inglês | MEDLINE | ID: mdl-35710073

RESUMO

The structural transition to generate amorphous translucent grains in Poria cocos dry extract (PCE) composite particles was found and studied as a new direct compression mechanism. The pressure and displacement sensing techniques were used to obtained stress-strain profiles during compression. The Exponential function, Kawakita model, Shapiro model and Heckel model were used to analysis mechanical properties of powders. 12 parameters derived from compression models and powder physical properties were applied to partial least squares method (PLS) for analyzing powder compression mechanism. It was found that only the oven-dried PCE composite particles undergoes the structural transition and generate translucent grains scattered and embedded in tablet, and these tablets have excellent mechanical stability. The structural transition in plant dry extract as the PCE composite particles could be exploited to improve powder compression and tabletability.


Assuntos
Química Farmacêutica , Wolfiporia , Química Farmacêutica/métodos , Tamanho da Partícula , Extratos Vegetais , Pós , Comprimidos/química
2.
J Anim Sci ; 91(9): 4374-82, 2013 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-23825327

RESUMO

We performed a series of trials to assess the effect of dietary supplementation with microencapsulated Enterococcus fecalis CG1.0007 on growth performance, antioxidation activity, and intestinal microbiota in Arbor Acres broiler chickens ("broilers"). A total of 150 1-d-old broilers were assigned randomly to 5 feeding treatments (a control group fed the basal diet, 3 groups fed the basal diet plus various concentrations of microencapsulated CG1.0007, and 1 group fed the basal diet plus an antibiotic). Changes in important genera of intestinal bacteria were studied using 16S rRNA gene-based PCR-denaturing gradient gel electrophoresis (DGGE) profiling and real-time quantitative PCR analysis of fecal samples. During the course of the 42-d experimental period, ADG of the birds fed the high and intermediate concentrations of microcapsules were significantly greater (9.90 and 9.50%, respectively) and the ratios of feed to gain fed were significantly lower (4.40 and 4.00%, respectively) compared with the control group. The total antioxidant capacity and the content of malondialdehyde and superoxide dismutase in the microcapsule-treated groups showed significant changes in terms of antioxidation. The numbers of Lactobacillus and Bifidobacterium were significantly greater in the microcapsule-treated groups than in the control group. Cluster analysis indicated that the DGGE bacterial profiles were related to the feeding treatments and revealing the diversity and richness of the intestinal microbiota associated with supplementation of microcapsules. In summary, our results indicate that dietary addition of microencapsulated E. fecalis CG1.0007 enhanced the growth performance of the broilers and improved their health.


Assuntos
Antioxidantes/metabolismo , Galinhas/microbiologia , Galinhas/fisiologia , Enterococcus faecalis/fisiologia , Intestinos/microbiologia , Probióticos/farmacologia , Ração Animal/análise , Animais , Bifidobacterium/efeitos dos fármacos , Bifidobacterium/crescimento & desenvolvimento , Galinhas/crescimento & desenvolvimento , Eletroforese em Gel de Gradiente Desnaturante , Dieta/veterinária , Suplementos Nutricionais/análise , Enterococcus faecalis/genética , Enterococcus faecalis/isolamento & purificação , Fezes/microbiologia , Feminino , Lactobacillus/efeitos dos fármacos , Lactobacillus/crescimento & desenvolvimento , Masculino , Microbiota/efeitos dos fármacos , Probióticos/administração & dosagem , RNA Bacteriano/genética , RNA Bacteriano/metabolismo , RNA Ribossômico 16S/genética , RNA Ribossômico 16S/metabolismo , Reação em Cadeia da Polimerase em Tempo Real/veterinária
3.
Water Sci Technol ; 56(9): 167-75, 2007.
Artigo em Inglês | MEDLINE | ID: mdl-18025744

RESUMO

This work experimentally studied the effects of ozonation treatment on waste sludge. During the treatment process, various parameters characterizing sludge were investigated. A substantial reduction in the volume of sludge and the release of intracellular and extracellular materials were observed. With the increase of ozone dose, the settleability and water content of sludge improved obviously, but the filterability of sludge deteriorated drastically. In addition, the evolution of particle size was evaluated, which proved the breakup of sludge flocs and cells. There existed a threshold of ozone dose which was 0.04 gO(3)/gMLSS in this work. Above the threshold, the soluble chemical oxygen demand (SCOD), protein, carbohydrate, total nitrogen and total phosphorus in supernatant increased remarkably and the electron transport system (ETS) sludge activity decreased. Organic nitrogen and organic phosphorus occupied the main part of total nitrogen and total phosphorus in the supernatant.


Assuntos
Ozônio/química , Esgotos/química , Carboidratos/análise , Carboidratos/química , Nitrogênio/análise , Nitrogênio/química , Oxigênio/química , Tamanho da Partícula , Fósforo/análise , Fósforo/química , Proteínas/análise , Proteínas/química , Eliminação de Resíduos Líquidos/métodos
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