RESUMO
The retrospective analysis of surgical and rehabilitation treatment of 172 patients with neurotrauma was made. The patients were treated in Russian Polenov Neurosurgical Institute and Municipal hospital of St. Elizabeth in the period since 2009 till 2012. Rehabilitation of different types of neurotrauma presented the system of surgical and recovery methods of treatment, which should be used in a short term after damage. Means of internal cerebral decompression, including drainage of ecephalocoel and cerebral basal cistern and the tentoriotomy, should be used in acute period of craniocerebral trauma according to morphometric data of beam inspection. Management of wound by means of laser or LED radiation, SHWF-therapy, magnetic and electrostimulation were the effective methods of neurorehabilitation. It is noted, that 73 (43,4%) patients returned to a former employment rate among 172 victims, though 26 patients had a moderate invalidization. An average figures of Glasgow scale outcomes were 1,9+/-0,2.
Assuntos
Procedimentos Neurocirúrgicos/reabilitação , Reabilitação , Traumatismos do Sistema Nervoso/cirurgia , Adulto , Avaliação da Deficiência , Intervenção Médica Precoce , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Procedimentos Neurocirúrgicos/efeitos adversos , Procedimentos Neurocirúrgicos/métodos , Período Pós-Operatório , Recuperação de Função Fisiológica , Reabilitação/classificação , Reabilitação/métodos , Reabilitação/estatística & dados numéricos , Estudos Retrospectivos , Tempo para o Tratamento , Resultado do TratamentoRESUMO
A fall in the glutathione peroxidase, glutathione reductase activity and selenium concentration was recorded in the liver of rats given diets poor in protein. The hepatic antioxidizing activity was lowered, lipid peroxidation (LPO) was intensified which was expressed in the growth of the amount of conjugated dienes, diene ketones and malonic dialdehydes. Diets poor in protein supplemented with sodium selenite and alpha-tocopherol acetate induced a significant increase in the selenium concentration and intensified the hepatic glutathione peroxidase and glutathione reductase activity. The rise in the oxide reductase activity was attended by a decreased rate of accumulation of LPO products, their amount being significantly lower as compared to that in the animals who were not given antioxidants.