RESUMO
OBJECTIVE: The objective of this study was to define the current forms of treatment in a contemporary population of lymphedema (LED) patients for LED related to breast cancer, the most prevalently diagnosed LED comorbidity in Western countries, and phlebolymphedema with venous leg ulcer (PLEDU), a sequela of chronic venous disease. The goals of LED therapy are to reduce edema, thereby improving function and related symptoms, and to improve skin integrity to prevent development of infection. Treatment is generally nonsurgical: conservative care, including complex physical therapy, manual lymphatic drainage, and compression bandaging; or pneumatic compression device (PCD) therapy by a simple nonprogrammable device or an advanced programmable device. METHODS: To determine the frequency of individual types of treatment for LED and their relationship to breast cancer-related lymphedema (BCRL) and PLEDU, we queried claims from a deidentified Health Insurance Portability and Accountability Act-compliant commercial administrative insurance database with >165 million members. A total of 26,902 patients identified with LED who had been enrolled with continuous medical benefits for 12 months before and after the index date for the complete years 2012 through 2016 were separated into four treatment categories: no treatment, conservative care, simple PCD (SPCD), and advanced PCD. LED treatment was related to the BCRL and PLEDU comorbidities. RESULTS: BCRL patients, who represented 32.1% of all study patients, made up 41% of all patients receiving conservative care and 24% of patients receiving PCD therapy. By contrast, PLEDU patients (9.6% of study patients) were proportionally under-represented in the conservative care group (7.8%) but composed a disproportionately high share of the PCD therapy group (17.7%). PLEDU patients represented 23.5% of all LED patients prescribed SPCD therapy, whereas BCRL patients composed 10.3% of total LED patient SPCD prescriptions (P < .001). CONCLUSIONS: Our analysis of a large health care administrative database showed clear differences between the way BCRL and PLEDU patients are treated. Compared with BCRL patients, PLEDU patients were less likely to receive conservative care and more likely to be prescribed SPCDs for pneumatic compression therapy. These differences suggest that lymphatic therapy may be undervalued for treatment of chronic venous swelling and prevention and treatment of PLEDU.
Assuntos
Linfedema Relacionado a Câncer de Mama/terapia , Bandagens Compressivas/tendências , Tratamento Conservador/tendências , Drenagem/tendências , Dispositivos de Compressão Pneumática Intermitente/tendências , Linfedema/terapia , Modalidades de Fisioterapia/tendências , Úlcera Varicosa/terapia , Insuficiência Venosa/terapia , Adolescente , Adulto , Idoso , Linfedema Relacionado a Câncer de Mama/diagnóstico , Linfedema Relacionado a Câncer de Mama/epidemiologia , Criança , Pré-Escolar , Doença Crônica , Comorbidade , Bases de Dados Factuais , Feminino , Humanos , Lactente , Recém-Nascido , Seguro Saúde , Linfedema/diagnóstico , Linfedema/epidemiologia , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Estados Unidos/epidemiologia , Úlcera Varicosa/diagnóstico , Úlcera Varicosa/epidemiologia , Insuficiência Venosa/diagnóstico , Insuficiência Venosa/epidemiologia , Adulto JovemRESUMO
Nearly 70% of older adults in the U.S. report using ≥1 dietary supplements (DSs) daily. While DSs may have health benefits, there is risk for toxicity or harmful drug-supplement interactions if not taken correctly. Older adults with chronic wounds who use DSs are at increased risk of adverse drug-supplement interactions because they usually have comorbidities requiring polypharmacy management. However, no studies have evaluated DS use in this population. The aim of this retrospective pilot study was to describe DS use by a sample of older adults (n = 40) with chronic venous leg ulcers (CVLUs) who participated in a clinical trial testing the effects of fish oil supplementation on wound healing. At baseline, study personnel assisted all participants in completing an electronic questionnaire about DS use. Descriptive statistics were used to characterize the data. Twenty-five of the 40 participants (62.5%) reported taking ≥1 DS daily. On average, DS users were 65.16 years (SD = 8.51) and the majority were men (64.0%), white (68.0%), and had at least some college education (72.0%). Fifteen (60.0%) reported taking 1-2 DSs/day, and 10 (40.0%) reported taking ≥3/day. The most frequently reported DSs used were multivitamin/mineral complex (60.0%), vitamin D (36.0%), vitamin B complex (28.0%) and calcium (28.0%). Reasons for using DSs were to maintain or improve health (44.0%), improve bone density (12%), and boost the immune system (12%). Supplement users reported consuming an average of 9.12 (SD = 6.46) prescription drugs daily and 21 (84.0%) reported ≥3 chronic health conditions. In summary, DS use in this sample of chronic wound patients was high. Moreover, DS users reported using multiple prescription drugs (2-23/day) concomitantly with DSs. While older adults with CVLUs may benefit from targeted DS therapy, monitoring their DS use to reduce risk for adverse drug-supplement interactions is best practice.
Assuntos
Suplementos Nutricionais/estatística & dados numéricos , Polimedicação , Oligoelementos/uso terapêutico , Úlcera Varicosa/epidemiologia , Vitaminas/uso terapêutico , Idoso , Idoso de 80 Anos ou mais , Artrite/epidemiologia , Cálcio/uso terapêutico , Depressão/epidemiologia , Diabetes Mellitus/epidemiologia , Interações Medicamentosas , Feminino , Óleos de Peixe/uso terapêutico , Cardiopatias/epidemiologia , Humanos , Masculino , Pessoa de Meia-Idade , Multimorbidade , Projetos Piloto , Medicamentos sob Prescrição/uso terapêutico , Ensaios Clínicos Controlados Aleatórios como Assunto , Estudos Retrospectivos , Inquéritos e Questionários , Úlcera Varicosa/terapia , Complexo Vitamínico B/uso terapêutico , Vitamina D/uso terapêuticoRESUMO
OBJECTIVE: Venous disease is common in Latin America, with an estimated 68.11% prevalence of chronic venous disease. The diverse social, political, and economic characteristics of the many nations that make up Latin America mean that different conditions affect how these diseases are diagnosed and treated, which may differ markedly from the way they are treated by the health care systems of the United States and Europe. Our goal was to review the current state of treatment of chronic venous insufficiency (CVI) in Latin America. METHODS: This is a narrative review of the medical literature on the subject and synthesizes sometimes fragmentary information on CVI across a large and diverse region. RESULTS: CVI represents an unmet medical need in Latin America. Conservative treatments, such as compression stockings, may be used at first, and there are nonpharmacologic and complementary and alternative medicine approaches in use. Endovenous approaches, such as endovenous thermal ablation, have largely replaced surgical interventions. In Europe and the United States, such procedures are mainly carried out in ambulatory facilities, whereas they are mainly performed in the hospital in Latin America. CONCLUSIONS: Recent strong economic growth in Latin America and improvements in social security and health care suggest that innovative approaches to chronic venous disease and CVI will be implemented.
Assuntos
Técnicas de Ablação , Fármacos Cardiovasculares/uso terapêutico , Procedimentos Endovasculares , Escleroterapia , Meias de Compressão , Úlcera Varicosa/terapia , Insuficiência Venosa/terapia , Técnicas de Ablação/efeitos adversos , Idoso , Idoso de 80 Anos ou mais , Fármacos Cardiovasculares/efeitos adversos , Doença Crônica , Procedimentos Endovasculares/efeitos adversos , Feminino , Humanos , América Latina/epidemiologia , Masculino , Escleroterapia/efeitos adversos , Meias de Compressão/efeitos adversos , Resultado do Tratamento , Úlcera Varicosa/diagnóstico por imagem , Úlcera Varicosa/epidemiologia , Insuficiência Venosa/diagnóstico por imagem , Insuficiência Venosa/epidemiologiaRESUMO
Introduction. Chronic illness and risk factors for chronic illness are rising public health concerns for individuals and health care systems. Individuals with venous leg ulceration (VLU) have at least one chronic illness. As there is a projected increase in VLU prevalence there is a need to determine concurrent prevalence of risk factors for chronic illness among this population. Methods. A cross-sectional design conducted in 8 community, nurse-led, leg ulcer clinics. Results. Fifty patients (58%, n = 29 females) were enrolled. Seventy percent were >65 years old; 90% had at least one chronic illness; 60% had hypertension; 30% had atrial fibrillation; 18% had diabetes; 18% heart failure; and 28.6% musculoskeletal conditions. All had at least one risk factors for chronic illness (mean = 2.26), the most frequent being overweight (30%), obesity (30%), high cholesterol (22.2%), and restricted physical activity (22%). Participants took a mean 5.2 medications daily and 26% were on current oral antibiotics. Conclusions. Comprehensive, holistic assessment and regular reassessment with a preventative focus needs to consider chronic illness and risk factors for chronic illness. Patients with VLU are in frequent contact with their multidisciplinary team. This is an opportunity to improve care and make every encounter count.
Assuntos
Doença Crônica/epidemiologia , Hipercolesterolemia , Sobrepeso , Úlcera Varicosa , Atividades Cotidianas , Idoso , Estudos Transversais , Feminino , Saúde Holística , Humanos , Hipercolesterolemia/diagnóstico , Hipercolesterolemia/epidemiologia , Irlanda/epidemiologia , Úlcera da Perna , Masculino , Sobrepeso/diagnóstico , Sobrepeso/epidemiologia , Prevalência , Medição de Risco , Fatores de Risco , Úlcera Varicosa/diagnóstico , Úlcera Varicosa/epidemiologia , Úlcera Varicosa/fisiopatologiaRESUMO
The quality of life (QoL) in patients with advanced venous insufficiency (including venous stasis ulcers, skin discoloration, stasis eczema, and lipodermatosclerosis) assessed using the Clinical Etiological Anatomical Pathophysiological (CEAP) and Venous Clinical Severity Score (VCSS) classifications is presented. Also, disease features such as: intensity of pain, edema and inflammatory response that exerted the most profound effect on different domains of QoL are reported. The global QoL in patients with lower leg venous ulcerations was relatively similar to that observed in other patients with chronic venous insufficiency. The presence of venous ulcerations was associated with lower QoL in a Physical domain. Significant correlations were found between pain intensity and the values of Physical, Physiological, Level of Independence and Environmental domains, between edema intensity and Social domain as well as between the intensity of inflammatory response and Physical and Spiritual domains.
Assuntos
Qualidade de Vida/psicologia , Úlcera Varicosa/epidemiologia , Úlcera Varicosa/psicologia , Insuficiência Venosa/epidemiologia , Insuficiência Venosa/psicologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Dor/epidemiologia , Polônia/epidemiologia , Índice de Gravidade de DoençaAssuntos
Prestação Integrada de Cuidados de Saúde/organização & administração , Equipe de Assistência ao Paciente/organização & administração , Serviços Preventivos de Saúde/organização & administração , Úlcera Varicosa/prevenção & controle , Idoso , Idoso de 80 Anos ou mais , Medicina Baseada em Evidências , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Objetivos Organizacionais , Guias de Prática Clínica como Assunto , Desenvolvimento de Programas , Avaliação de Programas e Projetos de Saúde , Suécia/epidemiologia , Fatores de Tempo , Resultado do Tratamento , Úlcera Varicosa/diagnóstico , Úlcera Varicosa/epidemiologiaAssuntos
Prestação Integrada de Cuidados de Saúde/organização & administração , Equipe de Assistência ao Paciente/organização & administração , Serviços Preventivos de Saúde/organização & administração , Úlcera Varicosa/diagnóstico , Úlcera Varicosa/prevenção & controle , Anticoagulantes/uso terapêutico , Atitude do Pessoal de Saúde , Testes de Coagulação Sanguínea , Educação de Pós-Graduação em Enfermagem , Medicina Baseada em Evidências , Conhecimentos, Atitudes e Prática em Saúde , Humanos , Objetivos Organizacionais , Guias de Prática Clínica como Assunto , Fatores de Tempo , Resultado do Tratamento , Úlcera Varicosa/epidemiologiaAssuntos
Prestação Integrada de Cuidados de Saúde/tendências , Serviços Preventivos de Saúde/tendências , Úlcera Varicosa/prevenção & controle , Atitude do Pessoal de Saúde , Educação de Pós-Graduação em Medicina , Medicina Baseada em Evidências , Previsões , Conhecimentos, Atitudes e Prática em Saúde , Humanos , Equipe de Assistência ao Paciente/tendências , Guias de Prática Clínica como Assunto , Desenvolvimento de Programas , Fatores de Tempo , Úlcera Varicosa/diagnóstico , Úlcera Varicosa/epidemiologiaAssuntos
Prestação Integrada de Cuidados de Saúde , Equipe de Assistência ao Paciente , Úlcera Varicosa/prevenção & controle , Atitude do Pessoal de Saúde , Análise Custo-Benefício , Prestação Integrada de Cuidados de Saúde/economia , Prestação Integrada de Cuidados de Saúde/legislação & jurisprudência , Prestação Integrada de Cuidados de Saúde/organização & administração , Educação de Pós-Graduação em Medicina , Medicina Baseada em Evidências , Fidelidade a Diretrizes , Custos de Cuidados de Saúde , Conhecimentos, Atitudes e Prática em Saúde , Política de Saúde , Humanos , Objetivos Organizacionais , Equipe de Assistência ao Paciente/economia , Equipe de Assistência ao Paciente/legislação & jurisprudência , Equipe de Assistência ao Paciente/organização & administração , Guias de Prática Clínica como Assunto , Prevalência , Serviços Preventivos de Saúde/economia , Serviços Preventivos de Saúde/legislação & jurisprudência , Serviços Preventivos de Saúde/organização & administração , Desenvolvimento de Programas , Apoio à Pesquisa como Assunto , Fatores de Tempo , Úlcera Varicosa/economia , Úlcera Varicosa/epidemiologiaAssuntos
Efeitos Psicossociais da Doença , Guias de Prática Clínica como Assunto , Úlcera Varicosa , França/epidemiologia , Diretrizes para o Planejamento em Saúde , Humanos , Incidência , Programas Nacionais de Saúde , Dor/etiologia , Dor/psicologia , Qualidade de Vida , Úlcera Varicosa/epidemiologia , Úlcera Varicosa/etiologia , Úlcera Varicosa/terapiaRESUMO
Venous leg ulcers affect approximately 0.6% of the western population, consuming millions of healthcare dollars every year. To determine whether an alternative venous ulcer treatment using horsechestnut seed extract-- Aesculus hippocastanum-- and conventional therapy involving dressings and compression was more cost-effective than using conventional therapy alone, a 12-week cost-benefit analysis of horsechestnut seed extract therapy was conducted. The study, using data from a 12-week prospective, randomized, placebo-controlled trial conducted in South Australia in 2002-2004, involved 54 patients with venous ulceration who received treatment through a large South Australian district nursing service. Taking into account the cost of horsechestnut seed extract, dressing materials, travel, staff salaries, and infrastructure for each patient, horsechestnut seed extract therapy combined with conventional therapy was found to be more cost-effective than conventional therapy alone with an average savings of AUD 95 in organizational costs and AUD 10 in dressing materials per patient. This study confirms that dressing change frequency has a significant impact on the total cost of wound care and suggests that district nursing service operation efficiency may be enhanced through the use of horsechestnut seed extract as a result of less frequent nursing visits. Further study of this treatment modality is warranted.