Assuntos
Benzoatos/efeitos adversos , Hidrazinas/efeitos adversos , Isquemia/etiologia , Púrpura Trombocitopênica Idiopática/tratamento farmacológico , Pirazóis/efeitos adversos , Trombose/induzido quimicamente , Idoso , Biópsia , Clopidogrel/uso terapêutico , Angiografia por Tomografia Computadorizada , Tratamento Conservador , Feminino , Humanos , Oxigenoterapia Hiperbárica , Isquemia/patologia , Isquemia/terapia , Contagem de Plaquetas , Púrpura Trombocitopênica Idiopática/sangue , Pele/irrigação sanguínea , Pele/diagnóstico por imagem , Pele/patologia , Trombose/complicações , Trombose/diagnóstico , Trombose/tratamento farmacológico , Artérias da Tíbia/diagnóstico por imagem , Artérias da Tíbia/patologia , Dedos do Pé/irrigação sanguínea , Dedos do Pé/diagnóstico por imagem , Dedos do Pé/patologia , Resultado do Tratamento , Varfarina/uso terapêuticoRESUMO
OBJECTIVE: To observe the effect of Tongmai Recipe (TMR) on atherosclerosis (AS) in patients with early lower extremity arteriopathy disease (LEAD) caused by type 2 diabetes mellitus (T2DM). METHODS: Patients were randomly assigned to two groups. The 23 patients in the treatment group were treated by TMR and the 22 in the control group were given Cilostazo, all for 3 months. Before and after treatment, lower extremity vascular color Doppler image, blood levels of glucose, insulin, serum matrix metalloproteinase-9 (MMP-9) and interleukin-6 (IL-6) were measured. RESULTS: The thickness of AS plaque and that of arterial intima-media obviously reduced (P < 0.01 and P < 0.05), insulin sensitivity improved noticeably (P < 0.01), and serum levels of MMP-9 and IL-6 lowered obviously (P < 0.05) in the treatment group after treatment, but these indexes were unchanged in the control group statistically. CONCLUSION: TMR has remarkable action in reducing the thickness of AS plaque and intima-media of artery, its mechanism might be related with improving of insulin sensitivity and anti-inflammatory reaction, and reducing of serum MMP-9 level as well in patients.
Assuntos
Arteriosclerose/tratamento farmacológico , Diabetes Mellitus Tipo 2/complicações , Medicamentos de Ervas Chinesas/uso terapêutico , Extremidade Inferior/irrigação sanguínea , Fitoterapia , Adulto , Idoso , Arteriosclerose/diagnóstico por imagem , Arteriosclerose/etiologia , Diabetes Mellitus Tipo 2/tratamento farmacológico , Feminino , Humanos , Resistência à Insulina , Interleucina-6/sangue , Masculino , Metaloproteinase 9 da Matriz/sangue , Medicina Tradicional Chinesa , Pessoa de Meia-Idade , Artérias da Tíbia/diagnóstico por imagem , Artérias da Tíbia/patologia , UltrassonografiaRESUMO
We present two cases of recurrent cavernous hemangiomas of the extremities. These conditions were initially treated unsuccessfully with surgical resection. After recurrence, the hemangiomas were treated by percutaneous transcatheter embolization. To the best of our knowledge, this is the first case report of treatment of cavernous hemangioma involving the extremities using an angiographically directed vascular embolization technique.