RESUMO
INTRODUCTION: Zoon balanitis is an idiopathic benign inflammatory condition of the glans penis and prepuce. A patient with biopsy confirmed diagnosis of Zoon balanitis who was successfully treated with topical mupirocin ointment monotherapy is described.
METHOD: A search using PubMed database was performed using the following terms: Zoon balanitis (cases, diagnosis, treatment of), balanitis circumscripta plasmacellularis, and mupirocin. Relevant papers and their reference citations were reviewed and evaluated.
RESULTS: The gold standard of treatment for Zoon balanitis has previously been circumcision. More recently, topical calcineurin inhibitors have been shown to be effective. Our patient had successful resolution of his Zoon balanitis after 3 months of mupirocin ointment monotherapy.
DISCUSSION: Zoon balanitis is a benign inflammatory dermatosis. Previous successful treatment modalities include circumcision, phototherapy, laser therapy, and topical calcineurin inhibitors. Topical mupirocin ointment twice daily resulted in resolution of Zoon balanitis in our patient. Additional evaluation of mupirocin ointment as a therapeutic agent should be considered as a potential first-line therapy in patients with Zoon balanitis.
J Drugs Dermatol. 2017;16(3):285-287.
.Assuntos
Antibacterianos/uso terapêutico , Balanite (Inflamação)/diagnóstico , Balanite (Inflamação)/terapia , Mupirocina/uso terapêutico , Antibacterianos/administração & dosagem , Anti-Infecciosos Locais/uso terapêutico , Balanite (Inflamação)/etiologia , Balanite (Inflamação)/patologia , Biópsia , Inibidores de Calcineurina/uso terapêutico , Circuncisão Masculina , Clotrimazol/administração & dosagem , Clotrimazol/uso terapêutico , Diagnóstico Diferencial , Humanos , Masculino , Pessoa de Meia-Idade , Mupirocina/administração & dosagem , Pomadas , Pênis/patologia , Fototerapia , Resultado do TratamentoAssuntos
Humanos , Adulto , Artrite Reativa/diagnóstico , Artrite Reativa/patologia , Artrite Reativa/terapia , Chlamydia trachomatis/classificação , Chlamydia trachomatis/patogenicidade , Balanite (Inflamação)/complicações , Balanite (Inflamação)/diagnóstico , Balanite (Inflamação)/terapia , Conjuntivite/complicações , Conjuntivite/diagnóstico , Conjuntivite/fisiopatologiaRESUMO
Chancroid, an ulcerous disease of the genitalia caused by Haemophilus ducreyi, occurs rarely but regularly in Germany. Exact diagnosis is based on the clinical features and a direct smear, and in particular on cultivation of the organism, showing its unique macromorphological characteristics. The sensitivity of cultivation has increased due to the development of selective media for primary isolation. Resistance problems during the last decade meant that a change to new therapeutic strategies was unavoidable. The work presented here includes a case report and a review of the recent literature, it illustrates modern methods of diagnosis and treatment of Haemophilus ducreyi infections 100 years after the first description of the organism.