[The cytoarchitectonics of hard chancre in rabbits with experimental syphilis exposed to soliusul'fon and cefamezine]. / Tsitoarkhitektonika tverdogo shankra u krolikov s éksperimental'nym sifilisom pri vozdeistvii soliusul'fonom i tsefamezinom.

Twenty rabbits were infected with Treponema pallidum suspension. Ten animals were injected with solusulfone, the rest with cefamezin. Specific features of syphilis induced by a pool of Treponemas are described, such as T. pallidum ultrastructure, formation of a specific granule, form of the agent aggression. Solusulfone treatment was associated with activation of phagocytosis, that manifested by a shift of the incomplete/complete phagocytosis ratio towards the reaction completion; however, intact T. pallidum were detectable even in 72 hrs after the drug injection. Cefamezin had no effect on the cysts and cyst-like formations at the beginning of the treatment course but these forms of the agent were already undetectable in 48 hours.