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1.
J Dairy Sci ; 106(4): 2519-2534, 2023 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-36894430

RESUMO

Foot disorders are costly health disorders in dairy farms, and their prevalence is related to several factors such as breed, nutrition, and farmer's management strategy. Very few modeling approaches have considered the dynamics of foot disorders and their interaction with farm management strategies within a holistic farm simulation model. The aim of this study was to estimate the cost of foot disorders in dairy herds by simulating strategies for managing lameness. A dynamic and stochastic simulation model (DairyHealthSim) was used to simulate the herd dynamics, reproduction management, and health events. A specific module was built for lameness and related herd-level management strategies. Foot disorder occurrences were simulated with a base risk for each etiology [digital dermatitis (DD), interdigital dermatitis, interdigital phlegmon, sole ulcer (SU), white line disease (WLD)]. Two state machines were implemented in the model: the first was related to the disease-induced lameness score (from 1 to 5), and the second concerned DD-state transitions. A total of 880 simulations were run to represent the combination of the following 5 scenarios: (1) housing (concrete vs. textured), (2) hygiene (2 different scraping frequencies), (3) the existence of preventive trimming, (4) different thresholds of DD prevalence detected and from which a collective footbath is applied to treat DD, and (5) farmer's ability to detect lameness (detection rate). Housing, hygiene, and trimming scenarios were associated with risk factors applied for each foot disorder etiologies. The footbath and lameness detection scenarios both determined the treatment setup and the policy of herd observance. The economic evaluation outcome was the gross margin per year. A linear regression model was run to estimate the cost per lame cow (lameness score ≥3), per case of DD and per week of a cow's medium lameness duration. The bioeconomic model reproduced a lameness prevalence varying from 26 to 98% depending on the management scenario, demonstrating a high capacity of the model to represent the diversity of the field situations. Digital dermatitis represented half of the total lameness cases, followed by interdigital dermatitis (28%), SU (19%), WLD (13%), and interdigital phlegmon (4%). The housing scenarios dramatically influenced the prevalence of SU and WLD, whereas scraping frequency and threshold for footbath application mainly determined the presence of DD. Interestingly, the results showed that preventive trimming allowed a better reduction in lameness prevalence than spending time on early detection. Scraping frequency was highly associated with DD occurrence, especially with a textured floor. The regression showed that costs were homogeneous (i.e., did not change with lameness prevalence; marginal cost equals average cost). A lame cow and a DD-affected cow cost €307.50 ± 8.40 (SD) and €391.80 ± 10.0 per year on average, respectively. The results also showed a cost of €12.10 ± 0.36 per week-cow lameness. The present estimation is the first to account for interactions between etiologies and for the complex DD dynamics with all the M-stage transitions, bringing a high level of accuracy to the results.


Assuntos
Doenças dos Bovinos , Dermatite , Dermatite Digital , Doenças do Pé , Casco e Garras , Feminino , Animais , Bovinos , Coxeadura Animal/diagnóstico , Celulite (Flegmão)/complicações , Celulite (Flegmão)/veterinária , Doenças dos Bovinos/epidemiologia , Doenças do Pé/epidemiologia , Doenças do Pé/veterinária , Doenças do Pé/complicações , Dermatite/veterinária , Indústria de Laticínios
2.
Transpl Infect Dis ; 19(1)2017 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-27775824

RESUMO

Nontuberculous mycobacterial infections can often occur in individuals with adequate immune function. Such infections typically have cutaneous involvement and are caused by rapidly growing mycobacterium. Other nontuberculous mycobacteria species, like Mycobacterium haemophilum, almost always present as opportunistic infections occurring in severely immunocompromised hosts. Here, we present a complicated and protracted course of diagnosing M. haemophilum lower extremity cutaneous infection in a matched-unrelated donor stem cell transplant recipient.


Assuntos
Antibacterianos/uso terapêutico , Celulite (Flegmão)/tratamento farmacológico , Transplante de Células-Tronco Hematopoéticas/efeitos adversos , Leucemia Mieloide Aguda/cirurgia , Infecções por Mycobacterium não Tuberculosas/tratamento farmacológico , Mycobacterium haemophilum/isolamento & purificação , Infecções Oportunistas/tratamento farmacológico , Biópsia , Celulite (Flegmão)/complicações , Celulite (Flegmão)/diagnóstico , Celulite (Flegmão)/microbiologia , Ciprofloxacina/uso terapêutico , Claritromicina/uso terapêutico , Feminino , Doença Enxerto-Hospedeiro/diagnóstico , Doença Enxerto-Hospedeiro/tratamento farmacológico , Humanos , Hospedeiro Imunocomprometido , Terapia de Imunossupressão/efeitos adversos , Imunossupressores/efeitos adversos , Imunossupressores/uso terapêutico , Extremidade Inferior , Pessoa de Meia-Idade , Infecções por Mycobacterium não Tuberculosas/complicações , Infecções por Mycobacterium não Tuberculosas/diagnóstico , Infecções por Mycobacterium não Tuberculosas/microbiologia , Infecções Oportunistas/complicações , Infecções Oportunistas/diagnóstico , Infecções Oportunistas/microbiologia , Rifabutina/uso terapêutico , Tacrolimo/efeitos adversos , Tacrolimo/uso terapêutico , Doadores não Relacionados
3.
J Wound Care ; 23(10 Suppl): S14-7, 2014 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-25289649

RESUMO

This case study outlines the management of a patient with a venous leg ulcer whose swabs cultured Staphylococcus aureus and beta-haemolytic streptococcus group A while in hospital with cellulitis, which was treated with antibiotics as per sensitivities. However, the patient presented at the emergency department five weeks later with a diagnosis of invasive group A streptococcal disease resulting in necrotising fasciitis and streptococcal toxic shock syndrome. This paper describes the holistic care and wound management that the patient received.


Assuntos
Celulite (Flegmão)/complicações , Fasciite Necrosante/etiologia , Úlcera da Perna/complicações , Choque Séptico/microbiologia , Infecções Estreptocócicas/etiologia , Úlcera Varicosa/complicações , Idoso , Antibacterianos/uso terapêutico , Fasciite Necrosante/tratamento farmacológico , Humanos , Masculino , Choque Séptico/tratamento farmacológico , Staphylococcus aureus/efeitos dos fármacos , Infecções Estreptocócicas/diagnóstico , Infecções Estreptocócicas/tratamento farmacológico , Streptococcus pyogenes/efeitos dos fármacos , Resultado do Tratamento , Cicatrização
7.
Stomatologiia (Mosk) ; 87(4): 53-5, 2008.
Artigo em Russo | MEDLINE | ID: mdl-18833139

RESUMO

The duthor detected special changes in oral liquid of macro and trace substances concentrations and their ratio in dynamics of convalescence for 24 patients with odontogenic lymphadenitis complicated by phlegmon. It was established that termination of inflammatory process on earlier terms at addition in complex treatment of this pathology of polyvitaminic complex considerably lowering strontium concentration in oral liquid (Patent RU 2210378 from 20.08.2003).


Assuntos
Celulite (Flegmão) , Assistência Odontológica Integral/métodos , Linfadenite , Odontogênese/fisiologia , Vitaminas/uso terapêutico , Adolescente , Adulto , Idoso , Celulite (Flegmão)/complicações , Celulite (Flegmão)/diagnóstico , Celulite (Flegmão)/tratamento farmacológico , Feminino , Humanos , Linfadenite/complicações , Linfadenite/diagnóstico , Linfadenite/tratamento farmacológico , Masculino , Pessoa de Meia-Idade
8.
J Spinal Cord Med ; 31(3): 319-23, 2008.
Artigo em Inglês | MEDLINE | ID: mdl-18795486

RESUMO

OBJECTIVE: To describe a spinal epidural abscess that originated from cellulitis after moxibustion. METHODS: Case report. FINDINGS: A 78-year-old woman with diabetes mellitus was diagnosed with tetraplegia due to a cervical spinal epidural abscess extending to the thoracic spinal epidural space. The abscess was caused by osteomyelitis and cellulitis of the right third finger, which had been cauterized repeatedly with moxa. After surgical decompression and drainage of the spinal epidural abscess and comprehensive rehabilitation, motor strength and functional level improved. CONCLUSIONS: This case illustrates the risk of spinal epidural abscess in persons with diabetes mellitus who present with focal cellulitis and osteomyelitis.


Assuntos
Celulite (Flegmão)/complicações , Celulite (Flegmão)/etiologia , Dedos , Moxibustão/efeitos adversos , Osteomielite/complicações , Osteomielite/etiologia , Quadriplegia/etiologia , Idoso , Diabetes Mellitus/terapia , Feminino , Humanos , Imageamento por Ressonância Magnética/métodos , Moxibustão/métodos , Quadriplegia/patologia , Quadriplegia/cirurgia , Fatores de Tempo , Tomografia Computadorizada por Raios X/métodos
9.
Stomatologiia (Mosk) ; 86(5): 55-7, 2007.
Artigo em Russo | MEDLINE | ID: mdl-18163065

RESUMO

145 patients (60 with phlegmons of submandibular and submental regions, 85--with fractures of mandible) were observed and treated with the use of moving pulse magnetic field (MPMF) produced by special apparatus (AMO-ATOS-E, <>, Saratov-city), 60 patients with the same pathology were treated by traditional physical methods and served as control. Use of MPMF led to quicker patient recovery: quicker reduction (if compared with traditional physical methods of treatment) of oedema and soft tissue inflammatory infiltration, quicker relief from inflammatory reaction (according to data of cytokinin profile), improvement of tissue blood supply in the region of fractures in patients with mandible fractures. As the result--we had shortening treatment terms of such patients and complication number reduction.


Assuntos
Celulite (Flegmão)/terapia , Magnetismo/instrumentação , Magnetismo/uso terapêutico , Fraturas Mandibulares/complicações , Adulto , Celulite (Flegmão)/complicações , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Resultado do Tratamento
12.
Dermatol Online J ; 9(1): 8, 2003 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-12639466

RESUMO

Dissecting cellulitis (also called perifolliculitis capitis abscedens et suffodiens) manifests with perifollicular pustules, nodules, abscesses and sinuses that evolve into scarring alopecia. It predominantly occurs in African American men between 20-40 years of age, but can occasionally affect other races and women too. Associated musculoskeletal findings are sometimes reported. When it occurs with acne conglobata, hidradenitis suppurativa, and pilonidal cysts, the syndrome is referred to as the follicular occlusion triad or tetrad. Its course is chronic and relapsing, and treatment is often difficult. Medical therapies include isotretinoin, antibiotics, and prednisone. Destructive therapies include X-ray therapy, surgical excision, and skin grafting. Laser epilation of hair follicles is a promising new therapy for dissecting cellulitis.


Assuntos
Celulite (Flegmão)/diagnóstico , Adulto , Alopecia/etiologia , Celulite (Flegmão)/complicações , Celulite (Flegmão)/terapia , Progressão da Doença , Humanos , Masculino , Fototerapia
13.
Klin Lab Diagn ; (8): 5-8, 2001 Aug.
Artigo em Russo | MEDLINE | ID: mdl-11582677

RESUMO

Twenty-five patients with pyoinflammatory maxillofacial diseases treated in an inpatient setting in the Regional Dentistry Clinic of Krasnodar and 8 healthy volunteers were examined. After opening and draining of the purulent focus the patients were divided into 2 groups. Group 1 consisted of 21 patients treated by intravenous 0.04% sodium hypochlorite (SHC) and intravenous infusions of SHC-oxidized autoblood for 2-3 days. Group 2 (6 pts) was treated by intravenous infusions of SHC-oxidized autoblood for 6 days. The criteria of intoxication were erythrocyte resistance tests in hypotonic sodium chloride and at different concentrations of urea in isotonic medium. A new method for evaluating erythrogram deviations from reference values is proposed, which helps adequately assess the severity of intoxication.


Assuntos
Membrana Eritrocítica , Toxemia/diagnóstico , Adolescente , Adulto , Transfusão de Sangue Autóloga , Permeabilidade da Membrana Celular , Celulite (Flegmão)/complicações , Face , Hemólise , Humanos , Indicadores e Reagentes , Arcada Osseodentária , Pessoa de Meia-Idade , Osmose , Oxirredução , Sensibilidade e Especificidade , Hipoclorito de Sódio/química , Hipoclorito de Sódio/uso terapêutico , Toxemia/sangue , Toxemia/etiologia , Toxemia/terapia , Ureia
15.
Klin Khir ; (3): 27-8, 1998.
Artigo em Russo | MEDLINE | ID: mdl-9670724

RESUMO

The experience of treatment of 236 patients with cervical phlegmon, in 7 of whom with putrefactive phlegmon, was summarized. The treatment difficulties are due to rapid infection spreading, the possibility absence of timely laboratory confirmation of diagnosis. Operative intervention was conducted during two hour period of time after the hospitalization moment. An adequate detoxication therapy, hyperbaric oxygenation, antibiotic therapy was conducted to all of the patients, metrogyl was administered without fail. Two patients died because of mediastinitis (1) and the pulmonary artery thromboembolism (1).


Assuntos
Celulite (Flegmão)/cirurgia , Pescoço , Adulto , Antibacterianos/uso terapêutico , Antitricômonas/uso terapêutico , Celulite (Flegmão)/complicações , Celulite (Flegmão)/terapia , Feminino , Humanos , Oxigenoterapia Hiperbárica , Masculino , Metronidazol/uso terapêutico , Pessoa de Meia-Idade , Supuração , Fatores de Tempo
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