RESUMO
OBJECTIVE: To evaluate the effects of a food supplemented with fish oil omega-3 fatty acids on weight bearing in dogs with osteoarthritis. DESIGN: Randomized, double-blinded, controlled clinical trial. ANIMALS: 38 client-owned dogs with osteoarthritis examined at 2 university veterinary clinics. PROCEDURES: Dogs were randomly assigned to receive a typical commercial food (n = 16) or a test food (22) containing 3.5% fish oil omega-3 fatty acids. On day 0 (before the trial began) and days 45 and 90 after the trial began, investigators conducted orthopedic evaluations and force-plate analyses of the most severely affected limb of each dog, and owners completed questionnaires to characterize their dogs' arthritis signs. RESULTS: The change in mean peak vertical force between days 90 and 0 was significant for the test-food group (5.6%) but not for the control-food group (0.4%). Improvement in peak vertical force values was evident in 82% of the dogs in the test-food group, compared with 38% of the dogs in the control-food group. In addition, according to investigators' subjective evaluations, dogs fed the test food had significant improvements in lameness and weight bearing on day 90, compared with measurements obtained on day 0. CONCLUSIONS AND CLINICAL RELEVANCE: At least in the short term, dietary supplementation with fish oil omega-3 fatty acids resulted in an improvement in weight bearing in dogs with osteoarthritis.
Assuntos
Doenças do Cão/dietoterapia , Ácidos Graxos Ômega-3/uso terapêutico , Coxeadura Animal/dietoterapia , Osteoartrite/veterinária , Suporte de Carga/fisiologia , Animais , Fenômenos Biomecânicos , Doenças do Cão/patologia , Doenças do Cão/fisiopatologia , Cães , Método Duplo-Cego , Feminino , Óleos de Peixe/administração & dosagem , Óleos de Peixe/química , Coxeadura Animal/patologia , Masculino , Osteoartrite/dietoterapia , Osteoartrite/patologia , Osteoartrite/fisiopatologia , Estudos Prospectivos , Amplitude de Movimento Articular , Resultado do TratamentoAssuntos
Ração Animal , Fenômenos Fisiológicos da Nutrição Animal , Doenças do Pé/veterinária , Casco e Garras , Doenças dos Cavalos/dietoterapia , Coxeadura Animal/dietoterapia , Ração Animal/efeitos adversos , Ração Animal/normas , Criação de Animais Domésticos/métodos , Animais , Doenças do Pé/dietoterapia , Doenças do Pé/etiologia , Doenças dos Cavalos/etiologia , Cavalos , Inflamação/dietoterapia , Inflamação/etiologia , Inflamação/veterinária , Coxeadura Animal/etiologia , Óleo de Semente do Linho/administração & dosagem , MasculinoRESUMO
A hind leg lameness of dairy cows was investigated in south-east Queensland. Samples of bone, blood, saliva, faeces, urine and milk were collected from lame and normal cows, some of which had received a phosphorus supplement of 30 g per day. Results of these investigations are presented and discussed. Clinical observations and pathological examinations indicated that the disease was an arthropathy affecting either the coxo-femoral or femoro-tibial joints. The disease was present in 30% of herds surveyed. Each owner reported 2 to 3 lame cows. The affected cows could not be differentiated from the normal cows on biochemical grounds. An hypothesis is advanced to explain the reported response of lame animals to large supplements of phosphorus. Information which indicates that previous nutritional status and methods of production cannot be ignored as predisposing factors is presented.