RESUMO
19 adults were patch tested to urushiol, the allergen in poison ivy/oak, to determine their sensitivity to this allergen after working in a cashew nut shell oil (CNSO) processing plant. The cashew nut tree and poison ivy/oak are in the same botanical family. Anacardiaceae, and they share similar chemicals which cause allergic contact dermatitis. 13 of the 19 workers had a preemployment history of poison ivy sensitivity, with 10 developing CNSO dermatitis. After working in this factory for several months, 9 of the 13 noticed a decreased sensitivity or no sensitivity to poison ivy/oak. When tested to urushiol extract, only 3 reacted positively, 2 minimally. These results imply that hyposensitization to poison ivy/oak occurred in these employees after development of hardening to cashew nut shell oil.
Assuntos
Catecóis/efeitos adversos , Dermatite por Toxicodendron/imunologia , Dessensibilização Imunológica , Nozes/imunologia , Óleos de Plantas , Catecóis/imunologia , Dermatite por Toxicodendron/diagnóstico , Dermatite por Toxicodendron/etiologia , Exposição Ambiental , Indústria de Processamento de Alimentos , Humanos , Testes do EmplastroAssuntos
Dermatite por Toxicodendron/imunologia , Dessensibilização Imunológica , Administração Oral , Animais , Catecóis/administração & dosagem , Catecóis/imunologia , Dessensibilização Imunológica/história , Dessensibilização Imunológica/métodos , Cobaias , História do Século XX , Humanos , Injeções Intradérmicas , Injeções Intramusculares , Extratos Vegetais/efeitos adversos , Extratos Vegetais/imunologia , Plantas Tóxicas , Toxicodendron , Estados UnidosRESUMO
In both man and animals, cell-mediated immunity diminishes with advanced age. Because poison ivy is a very common allergy, we evaluated age-associated differences in the contact allergic reaction to Rhus. Oleoresin patch tests were applied to two age cohorts (18-25 versus 65-84) each of 14 healthy white subjects. In the elderly, the allergic reaction developed more slowly, the inflammatory response at peak was greatly diminished and the dermatitis lasted longer and seemed to be more pruritic.