RESUMO
La morfea superficial es una variante rara de morfea que se distingue de la clásica tanto en la clínica como en la histopatología. Se caracteriza por máculas hipopigmentadas o hiperpigmentadas, con mínima o ninguna induración, sin síntomas asociados, contractura ni atrofia. En la histopatología, se observa un compromiso limitado a las fibras colágenas en la dermis reticular superficial. Se comunica el caso de una paciente con diagnóstico de morfea superficial tratada con fototerapia ultravioleta B y metotrexato.
Superficial morphea is a rare variant of morphea that is distinguished from the classic variant both clinically and histopathologically. It is characterized by hypo or hyperpigmented patches with minimal to no induration, without associated symptoms, without contracture or atrophy. At the histopathological level, a limited involvement of collagen fibers is observed at the level of the uperficial reticular dermis. The case of a patient with superficial morphea treated with ultraviolet B phototherapy and methotrexate is presented.
Assuntos
Humanos , Feminino , Pessoa de Meia-Idade , Fototerapia/métodos , Esclerodermia Localizada/terapia , Esclerodermia Localizada/diagnóstico , Esclerodermia Localizada/tratamento farmacológico , Metotrexato/administração & dosagem , Derme/patologia , Ácido Fólico/administração & dosagemRESUMO
Abstract A 28-year-old white female patient presented with multiple erythematous-to-violaceous, painful, suppurative nodules on the buttocks and thighs that appeared after two weeks of mesotherapy with deoxycholate, caffeine, sunflower liposomes, and sinetrol for localized fat. She was treated for atypical mycobacteriosis, but with no satisfactory response after antibiotic therapy. Bacterial, mycobacterial, and fungal culture were all negative. Histopathologic examination of the biopsy showed noninfectious suppurative panniculitis. It resolved after treatment with methotrexate, prednisone, and hydroxychloroquine. This report highlights the rarity of this complication, the importance of its early recognition, and differentiation with atypical fast growing mycobacterioses.
Assuntos
Humanos , Feminino , Adulto , Paniculite Nodular não Supurativa/induzido quimicamente , Paniculite Nodular não Supurativa/patologia , Ácido Desoxicólico/efeitos adversos , Mesoterapia/efeitos adversos , Biópsia , Paniculite Nodular não Supurativa/tratamento farmacológico , Resultado do Tratamento , Derme/patologiaRESUMO
Acrodermatitis enteropathica is an uncommon disease caused by hereditary or acquired zinc deficiency. It is characterized by a triad of alopecia, diarrhea and acraland periorificial dermatitis. It is treated with Zinc supplementation. We report a31-year-old indigent and drug addict female with a cutaneous-mucous syndromecharacteristic of acrodermatitis enteropathica. She had a positive clinical evolutionafter Zinc supplementation.
Assuntos
Adulto , Feminino , Humanos , Acrodermatite/patologia , Derme/patologia , Zinco/deficiência , Acrodermatite/diagnóstico , Acrodermatite/tratamento farmacológico , Biópsia , Diagnóstico Diferencial , Zinco/metabolismo , Zinco/uso terapêuticoRESUMO
La acroqueratodermia siríngea acuagénica es una queratodermia adquirida y transitoria que se exacerba tras sumergir en agua las palmas y/o las plantas. Se manifiesta como pápulas y placas blanquecinas o amarillentas, translúcidas y aplanadas localizadas en las zonas de presión o traumatismo de palmas y/o plantas. La afectación suele ser bilateral. La histología es inespecífica, mostrando una ligera dilatación de la porción intraepidérmica del conducto excretor ecrino. El proceso tiende a la remisión espontánea. Presentamos el caso de 2 mujeres de 20 y 21 años que presentaban un cuadro de acroqueratodermia siríngea acuagénica de largo tiempo de evolución
Aquagenic syringeal acrokeratoderma is an infrequently described acquired, transitory keratoderma that is exacerbated when the palms and/or soles are immersed in water. It manifests as whitish or yellowish flattened, translucent papules and plaques, located in areas of pressure or trauma on the palms and/or soles. Involvement is usually bilateral. The histologic features are non-specific, showing a slight dilation of the intraepidermal portion of the eccrine sweat duct. The process tends to remit spontaneously. We present the case of two women, aged 20 and 21