RESUMO
La equinococosis quística es una zoonosis de origen parasitario con distribución cosmopolita. En nuestro país continúa siendo una enfermedad endémica, afectando principalmente pequeños centros poblados y áreas rurales pobres relacionadas a la producción ovina. Los planes de control requieren de un abordaje holístico, con la participación de diferentes instituciones, profesionales y en especial de la comunidad. La cooperación regional busca monitorizar el avance de la enfermedad y centrar las medidas de acción sobre cuatro ejes, definidos según los puntos de intervención más comunes para la quiebra del ciclo de transmisión y la consecuente reducción en incidencia y prevalencia de la enfermedad. La presente revisión utilizó literatura obtenida en diferentes bases de datos, bibliotecas virtuales y sitios web regionales y locales con el objetivo describir las principales estrategias de control, vigilancia y prevención aplicadas actualmente en nuestro país.
Cystic echinococcosis is a zoonosis of parasitic origin with cosmopolitan distribution. In our country it continues to be an endemic disease, affecting mainly small population centers and poor rural areas related to sheep production. Control plans require a holistic approach, with the participation of different institutions, professionals and especially the community. Regional cooperation seeks to monitor the progress of the disease and focus action measures on four axes, defined according to the most common points of intervention to break the transmission cycle and consequently reduce the incidence and prevalence of the disease. This review used literature obtained from different databases, virtual libraries and regional and local websites with the aim of describing the main control, surveillance and prevention strategies currently applied in our country.
A equinococose cística é uma zoonose de origem parasitária com distribuição cosmopolita. Em nosso país, continua a ser uma doença endêmica, afetando principalmente pequenos centros populacionais e áreas rurais pobres relacionadas à produção de ovinos. Os planos de controle exigem uma abordagem holística, com a participação de diferentes instituições, profissionais e, principalmente, da comunidade. A cooperação regional busca monitorar o progresso da doença e concentrar as medidas de ação em quatro eixos, definidos de acordo com os pontos de intervenção mais comuns para interromper o ciclo de transmissão e, consequentemente, reduzir a incidência e a prevalência da doença. Esta revisão utilizou a literatura obtida em diferentes bases de dados, bibliotecas virtuais e sites regionais e locais com o objetivo de descrever as principais estratégias de controle, vigilância e prevenção aplicadas atualmente em nosso país.
Assuntos
Humanos , Animais , Vigilância Sanitária , Equinococose/prevenção & controle , Vigilância de Zoonoses , Uruguai/epidemiologia , Equinococose/diagnósticoRESUMO
BACKGROUND: Echinococcosis is a neglected zoonosis of increasing public health concern worldwide. According to the World Health Organization, 19,300 lives and 871,000 disability-adjusted life-years are lost globally each year because of cystic echinococcosis. Annual costs associated with cystic echinococcosis were estimated at US$ 3 billion because of treatment of cases and losses in the livestock industry. METHODS: We performed the random-effects model of meta-analysis using 51-year (1970-2021) data available from AJOL, Google Scholar, PubMed, Science Direct, Scopus and Web of Science. We also applied the Joanna Briggs Institute critical appraisal instrument for studies reporting prevalence data, the Cochran's Q-test, Egger's regression test and the single study deletion technique to respectively examine within-study bias, heterogeneity, across-study bias and sensitivity. RESULTS: Thirty-nine eligible studies on human cystic echinococcosis (HCE) from 13 countries across the five African sub-regions showed an overall prevalence of 1.7% (95% CI 1.1, 2.6) with a statistically significant (P < 0.001) sub-group range of 0.0% (95% CI 0.0, 14.1) to 11.0% (95% CI 7.6, 15.7). Highest prevalences were observed in Eastern Africa (2.7%; 95% CI 1.4, 5.4) by sub-region and Sudan (49.6%; 95% 41.2, 58.1) by country. Another set of 42 studies on Echinococcus granulosus infections (EGI) in dogs from 14 countries across the five African sub-regions revealed an overall prevalence of 16.9% (95% CI 12.7, 22.3) with a significant (P < 0.001) variation of 0.4 (95% CI 0.0, 5.9) to 35.8% (95% CI 25.4, 47.8) across sub-groups. Highest prevalences of E. granulosus were observed in North Africa (25.6%; 95% CI 20.4, 31.6) by sub-region and Libya (9.2%; 95% CI 5.7, 13.9) by country. CONCLUSION: Human cystic echinococcosis and EGI are respectively prevalent among Africans and African dogs. We recommend a holistic control approach that targets humans, livestock, dogs and the environment, which all play roles in disease transmission. This approach should involve strategic use of anthelminthics in animals, standardized veterinary meat inspection in abattoirs, control of stray dogs to reduce environmental contamination and proper environmental sanitation. Mass screening of humans in hyper-endemic regions will also encourage early detection and treatment.
Assuntos
Equinococose , Echinococcus granulosus , Animais , Cães , Equinococose/diagnóstico , Equinococose/epidemiologia , Equinococose/veterinária , Humanos , Prevalência , Sudão , Zoonoses/epidemiologiaRESUMO
Cystic echinococcosis (CE) can be diagnosed by means of several serological approaches, but their results vary among laboratories due to the molecular characteristics of the reference antigens used. Thus, this study aimed to address both the relevance of an EGPE cell line previously obtained from Echinococcus granulosus protoscoleces G1 and the complexity of the immune response by using two different in vitro growth stages as separate sources of parasite antigens. The serum reactivity was investigated by western blotting (WB) in 21 CE patients from an endemic area in a matched case-control design and also in seven experimentally infected sheep and five healthy control sheep. EGPE-antigen-human serum sensitivity by WB was higher than that of hydatid fluid (HF) WB, ELISA and DD5 (P < .05, Chi-square test). EGPE protein extract was immunogenic in mice and hyperimmune plasma reacted with HF proteins, and AgB2 expression was detected by molecular analysis. Proteins of 37 to 60 kDa were recognized by 95.24% of the CE patients' sera but, with poor specificity. Statistically significant differences were found between serum protein extract recognition at 7 and 20 days of cell growth. The EGPE cell line is a laboratory source of antigens for improvement of CE serological diagnosis.
Assuntos
Anticorpos Anti-Helmínticos/imunologia , Antígenos de Helmintos/imunologia , Equinococose/veterinária , Echinococcus granulosus/imunologia , Ovinos/parasitologia , Animais , Western Blotting , Estudos de Casos e Controles , Linhagem Celular , Equinococose/diagnóstico , Equinococose/parasitologia , Echinococcus granulosus/isolamento & purificação , Ensaio de Imunoadsorção Enzimática/métodos , Feminino , Humanos , Masculino , Camundongos , Camundongos Endogâmicos BALB C , Pessoa de Meia-Idade , Extratos Vegetais , Ovinos/imunologiaRESUMO
Echinococcus granulosus is the causative agent of cystic echinococcosis (CE), which is distributed all around the world. CE is one of the most important global parasitic infectious diseases, both in humans and animals. This parasite causes hydatid cysts that can be lodge at different organs of host such as liver, lung even in heart and brain which may lead to death. Presently, numerous scolicidal chemical agents have been administrated for inactivation of the hydatid cyst contents. Because of increasing resistance and adverse effects of medications include abnormalities of liver function, abdominal pain, diarrhea, nausea, vomiting, dizziness, and headache; there is a need to find alternative therapies either with the least or without side effects. Recently, there is a high tendency among researchers to evaluate and present herbal plants as alternative option due to being inexpensive, easy available, low side effects and toxicity. Till now, many efforts have been conducted on herbal extracts against protoscolices of hydatid cysts throughout the world. Therefore, the current review systematically searched the following electronic databases: PubMed, Science Direct, Scopus, and Google Scholar on published papers according to the keywords. In addition, a comprehensive list of medicinal plants was prepared and some of these herbal plants which showed the best efficacy and promising results are discussed elaborately.
Assuntos
Equinococose/tratamento farmacológico , Echinococcus granulosus/efeitos dos fármacos , Plantas Medicinais , Animais , Produtos Biológicos/farmacologia , Equinococose/diagnóstico , Equinococose/epidemiologia , Equinococose/parasitologia , HumanosRESUMO
BACKGROUND: Alveolar echinococcosis is a potentially lethal zoonosis caused by larval forms of the tapeworm Echinococcus multilocularis. Humans are aberrant intermediate hosts who become infected by ingestion of egg-contaminated food or water or via physical contact with domestic or wild animals that carry the parasite in their small intestine. In humans, the disease usually affects the liver and can spread to other organs causing metastatic infiltration. In this report, we describe an advanced presentation of human alveolar echinococcosis mimicking metastatic malignancy. CASE PRESENTATION: A 62-year-old white woman was evaluated for fever, jaundice, and abdominal pain, associated with significant weight loss. She lived in a rural area in Switzerland and used to eat wild forest fruits and mushrooms. She owned cats that used to hunt rodents. On physical examination, she appeared severely ill with cachexia, altered mental status, jaundice, and massive hepatomegaly. Laboratory tests showed cholestasis with preserved liver function. An abdominal computed tomography scan showed an enlarged liver with a huge cystic mass in the right lobe extending into the left lobe, infiltrating her hepatic hilum, causing intrahepatic bile duct dilation and occlusion of her right portal vein. A chest computed tomography scan showed multiple calcified bilateral pulmonary nodules. Her clinical and radiological presentation resembled an advanced neoplastic disease. Serologic tests for Echinococcus multilocularis were positive. The diagnosis of alveolar echinococcosis was established on her past history of exposure, imaging, and serology results. CONCLUSIONS: Clinical presentation and radiologic imaging findings of disseminated alveolar echinococcosis can mimic metastatic malignancy, and diagnosis can be challenging in atypically advanced cases. As the incidence of human alveolar echinococcosis appears to be increasing in Europe and Switzerland, physicians should be aware of alveolar echinococcosis, its epidemiology, and its clinical features.
Assuntos
Albendazol/uso terapêutico , Anti-Helmínticos/uso terapêutico , Ductos Biliares/parasitologia , Equinococose/diagnóstico , Equinococose/terapia , Comportamento Alimentar , Fígado/parasitologia , Animais , Ductos Biliares/patologia , Gatos , Diagnóstico Diferencial , Drenagem , Equinococose/fisiopatologia , Doenças Endêmicas , Evolução Fatal , Feminino , Humanos , Fígado/patologia , Neoplasias Hepáticas/patologia , Pessoa de Meia-Idade , Insuficiência de Múltiplos Órgãos , Segunda Neoplasia Primária/patologia , Choque Séptico , SuíçaRESUMO
Integrating the control of multiple neglected zoonoses at the community-level holds great potential, but critical data is missing to inform the design and implementation of different interventions. In this paper we present an evaluation of an integrated health messaging intervention, using powerpoint presentations, for five bacterial (brucellosis and bovine tuberculosis) and dog-associated (rabies, cystic echinococcosis and leishmaniasis) zoonotic diseases in Sidi Kacem Province, northwest Morocco. Conducted by veterinary and epidemiology students between 2013 and 2014, this followed a process-based approach that encouraged sequential adaptation of images, key messages, and delivery strategies using auto-evaluation and end-user feedback. We describe the challenges and opportunities of this approach, reflecting on who was targeted, how education was conducted, and what tools and approaches were used. Our results showed that: (1) replacing words with local pictures and using "hands-on" activities improved receptivity; (2) information "overload" easily occurred when disease transmission pathways did not overlap; (3) access and receptivity at schools was greater than at the community-level; and (4) piggy-backing on high-priority diseases like rabies offered an important avenue to increase knowledge of other zoonoses. We conclude by discussing the merits of incorporating our validated education approach into the school curriculum in order to influence long-term behaviour change.
Assuntos
Recursos Audiovisuais , Educação em Saúde/métodos , Disseminação de Informação/métodos , Doenças Negligenciadas/diagnóstico , Doenças Negligenciadas/tratamento farmacológico , Zoonoses/diagnóstico , Zoonoses/tratamento farmacológico , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Animais , Brucelose/diagnóstico , Brucelose/tratamento farmacológico , Brucelose/epidemiologia , Bovinos , Criança , Currículo , Cães , Equinococose/diagnóstico , Equinococose/tratamento farmacológico , Equinococose/epidemiologia , Feminino , Pessoal de Saúde/educação , Humanos , Masculino , Pessoa de Meia-Idade , Marrocos/epidemiologia , Doenças Negligenciadas/epidemiologia , Pais/educação , Raiva/diagnóstico , Raiva/tratamento farmacológico , Raiva/epidemiologia , Instituições Acadêmicas , Estudantes , Tuberculose Bovina/diagnóstico , Tuberculose Bovina/tratamento farmacológico , Tuberculose Bovina/epidemiologia , Adulto Jovem , Zoonoses/epidemiologiaRESUMO
CASE DESCRIPTION: A 7-day-old female alpaca was examined because of an acute onset of diffuse central neurologic deficits. CLINICAL FINDINGS: Diagnostic imaging with CT and MRI identified an intracranial cyst occupying approximately one-third to one-half of the dorsal portion of the cranial cavity, markedly displacing the cerebral hemispheres bilaterally. TREATMENT AND OUTCOME: Initial surgical management via trephination and needle drainage was only transiently effective at resolving the neurologic signs. Craniotomy and drainage and removal of the cyst lining resulted in a sustained improvement in neurologic status, and the cria remained clinically normal and well grown at follow-up 5 months after surgery. CLINICAL RELEVANCE: This report represented the first description of the successful treatment of an intracranial cyst in a New World camelid.
Assuntos
Camelídeos Americanos , Equinococose/veterinária , Irrigação Terapêutica/veterinária , Animais , Camelídeos Americanos/parasitologia , Diagnóstico Diferencial , Equinococose/diagnóstico , Equinococose/cirurgia , Feminino , Seguimentos , Imageamento por Ressonância Magnética/veterinária , Tomografia Computadorizada por Raios X/veterinária , Resultado do TratamentoRESUMO
Hydatidosis is a parasitic disease due to Echinococcus granulosus. Spinal hytatidosis is the most common form, characterized by high morbidity and mortality. It is often diagnosed only when neurological complications occur, due to the long clinical latency and the non specific nature of symptoms. Standard radiography may show lacunar, areolar abnormalities separated by irregular walls without clear boundaries. Magnetic resonance imagery can reveal hydatic abcess presenting typical liquid abcess and locoregional extension. Laboratory methods are of little assistance to the diagnosis. Complete surgical excision of the lesions remains the only curative treatment, in the same way as for malignant tumors. Surgical eradication of hydatic lesions is difficult, however. Indeed, the surgeon is guided by the macroscopic aspect, but the bone may be infiltrated by microvesicles without clear boundaries. It is now recommended to accompany surgery by medical treatment based on albendazole. Rapid diagnosis and treatment of spinal hyatidosis may yield long-term remission or even cure, especially in localized forms.
Assuntos
Equinococose/diagnóstico , Equinococose/terapia , Doenças da Coluna Vertebral/diagnóstico , Doenças da Coluna Vertebral/terapia , Anti-Helmínticos/uso terapêutico , Humanos , Imageamento por Ressonância Magnética , Procedimentos NeurocirúrgicosRESUMO
The authors have detected atypical paecilomycosis-associated myocarditis with impaired amino acid exchange and pain syndrome for the first time. At first, pain occurs in the chest and radiates into the axilla, to the left arm to the finger tips, by paralyzing the arm. In some patients, pain manifests itself in both arms with radiation to the belly, by accompanying by fainting. The skin is wet, cold; the pulse is frequent and of poor volume and difficult-to-count. Heart pain spreads into the armpit and down the arm, by making the fingers numb. Attempts to use current analgesics (movalis, sirdalud, nimesil, morphine) in combination with fungicides (diflucan, mycosist, orungal) have failed to yield positive results. The homeopathic drug Latrodectus mactans, prepared from caracurt venom, in combination with the authors' designed diet and other homeopathic agents have relieved pain syndrome and normalized amino acid exchange, which offered possibilities for successful surgical treatment for echinococcosis with later recovery.
Assuntos
Aminoácidos/metabolismo , Equinococose/sangue , Echinococcus/fisiologia , Materia Medica/uso terapêutico , Micoses/sangue , Paecilomyces/crescimento & desenvolvimento , Venenos de Aranha/uso terapêutico , Adolescente , Adulto , Idoso , Analgésicos/administração & dosagem , Animais , Viúva Negra/química , Dieta , Equinococose/complicações , Equinococose/diagnóstico , Equinococose/tratamento farmacológico , Equinococose/parasitologia , Equinococose/cirurgia , Echinococcus/efeitos dos fármacos , Feminino , Fluconazol/administração & dosagem , Humanos , Fígado/efeitos dos fármacos , Fígado/metabolismo , Fígado/parasitologia , Fígado/cirurgia , Masculino , Materia Medica/administração & dosagem , Pessoa de Meia-Idade , Micoses/complicações , Micoses/diagnóstico , Micoses/tratamento farmacológico , Micoses/microbiologia , Miocardite/complicações , Paecilomyces/efeitos dos fármacos , Dor/complicações , Venenos de Aranha/químicaRESUMO
The hydatidosis is an endemic illness in regions of the Middle Orient, Mediterranean, south of America, north Africa and the Australia. The preferential localization of cyst hydatic is the liver (48%), the lung (36%) and in 6% of cases it localizes in unaccustomed place as the brain. Intracerebral localization is relatively rare, its impact is 1 to 5% of all cases of hydatidose. This localization is the child's appendage with a masculine predominance. The cyst hydatic intracranien is often lone, of localization usually supratentorielle, sometimes infratentorielle. Symptoms are especially the diffuse headache associated to various neurological signs in relation with sits of the tumor. The psychiatrics symptoms depends on its localization, sides, intracranial hypertension, and the previous personality. In 15 to 20% of cases these tumors can appear in the beginning of their evolution by the isolated psychiatric symptoms. We report the case of two patients that have been hospitalized first in the Academic Psychiatric Unit of Marrakech for isolates psychiatric disorders and whose scanning revealed the presence of cerebral hydatic cyst and that required a surgical intervention in neurosurgery. Case 1 - Patient 29 years old, bachelor, uneducated, leaving in country outside, fermar, in permanent contact with dogs. No particular medical history. The patient has been brought by his family to the psychiatric emergencies after behavior disorders. The beginning of his symptomatology was one year ago by behavior disorders: instability, violence, isolation, and a corporo-sartorial carelessness. His symptomatology worsened and the patient became very aggressive. In psychiatric unit, he was disregarded, sad, anguished, indifferent to his state, very dissonant, completely detached, depersonalized. He brought back some visual and auditory hallucinations with attitude of monitoring. He was raving with delirium of persecution, of ideas of reference and delirium of bewithment. He was unconscious of his disorders. The patient has first been put under classical neuroleptic 9 mg/day of Haloperidol and 200 mg/day of chlorpromazine. The diagnosis of schizophrenia has been kept according to criteria of DSM IV. The PANSS (Positive and Negative Syndrome Scale) was to 137 (score on a positive scale was to 34, score on a negative scale was to 35 and the general psychopathologie scale was to 58). One week after his hospitalization, he developed headache with subconfusion, a cerebral scanning has been made in emergency and showed a voluminous cyst in oval foramen compressing the mesencephalon strongly. The cyst was well limited, hypodense, not taking the contrast, and without intracerebral oedema, the diagnosis of cerebral hydatic cyst has been made. The complementary exploration didn't show any other localizations, and biologic exam results didn't show any particular anomalies. The patient has been operated in neurosurgery. The immediate evolution was favorable with disappearance of confusion and absence of complications. The patient was lost of view. Six months after, the patient has been readmitted to the psychiatric emergency. He dropped his neuroleptic treatment. He was aggressive, raving, hallucinated and depersonalized. The global score to the PANSS was 63. He has been put back under neuroleptics. Three weeks after improvement and passage of the PANSS to 30, the patient went out. We couldn't have a cerebral scanner of control because the patient had no medical assurance and no money for cerebral scanner. Case 2 - Patient aged of 53 years, father of four children, uneducated, native and resident of Marrakech, confectioner as profession. He is in contact with dogs since 12 years. He has been brought to the psychiatric emergencies by his family after an agitation. The history of his illness seemed to go back at eight months ago, by the progressive apparition of an instability, sleep disorders, hostility, associated with an emotional lability. To the interview he was agitated and had a delirium of persecution. He was convinced that his wife and his children plotted against him. He had sad mood. He was anguished and had auditory and visual hallucinations. The patient was not confused but it had a hypoproxie, an fixing amnesia, a disorders of judgment and a light left hemiparesia. Cerebral scanner revealed three cerebral cyst. The first measuring 42 x 40 mm, sitting at the level parietal right, to the contact of the occipital horn, dragging his/her/its amputation and an effect of mass on ventricle homolateral, the median line and ventricle controlateral. The two other, at the level of the center semi oval, behind the first, measuring 23 mm and 15 mm on the big axis. The patient has been addressed in neurosurgery. He had a completeray exploration to search other localizations. The thoracic x-ray showed 2 pulmonary cyts. The abdominal scan and imagery by magnetic resonance showed liver cyst, peri-heart cyst and mediastinal cyst. The patient has been operated for these three cysts with good recuperation on the psychiatric and neurological symptoms. He has been addressed in heart surgery for the heart localization. The hydatidose is an endemic illness in Morocco and constitute a public health problem. The cerebral localization is rare and appear by signs of cerebral hypertension and signs of focusing. The psychiatric demonstrations are rare but preserve a major interest, by the therapeutic measure specificity that they impose. Of course, the surgical ablation of the tumor can be sufficient to attenuate the psychiatric symptoms but the recourse to a specific treatment can prove to be necessary to act on the precise targets. We are conscious of the methodological difficulties that present these 2 cases but there are unfortunately due to the financial difficulties of our patients.
Assuntos
Infecções Parasitárias do Sistema Nervoso Central/parasitologia , Infecções Parasitárias do Sistema Nervoso Central/psicologia , Equinococose/parasitologia , Equinococose/psicologia , Transtornos Mentais/parasitologia , Transtornos Mentais/psicologia , Adulto , Diagnóstico Diferencial , Equinococose/diagnóstico , Alucinações/diagnóstico , Alucinações/parasitologia , Alucinações/psicologia , Humanos , Masculino , Transtornos Mentais/diagnóstico , Pessoa de Meia-IdadeRESUMO
The history of echinococcosis in Europe includes a period of over 2000 years. Already in antiquity metacestodes (hydatids) of Echinococcus granulosus, the causative agents of Cystic Echinococcosis (CE), were observed in animals and humans. Alveolar Echinococcosis (AE), caused by metacestodes of E. multilocularis, was identified as a disease entity only in the middle of the 19th century. It took about 100 years until it was undoubtedly clarified and accepted that CE and AE are not caused by a single Echinococcus species, but by E. granulosus and E. multilocularis, respectively. In the 20th century significant progress has been achieved in echinococcosis research, including diagnosis, epidemiology, therapy, immunology, molecular biology and other fields. However, CE and AE remain actual problems as in many endemic regions resources and structures are lacking for effective surveillance and control of these zoonoses threatening humans.
Assuntos
Equinococose/história , Medicina Veterinária/história , Animais , Equinococose/diagnóstico , Equinococose/tratamento farmacológico , Equinococose/veterinária , História do Século XVII , História do Século XVIII , História do Século XIX , História do Século XX , História do Século XXI , História Antiga , Humanos , SuíçaRESUMO
We present a case of cerebral infestation by Echinococcosis multilocularis mimicking an infiltrative primary brain tumor. A heavily calcified mass invading the midbrain enhanced in a cauliflower-like fashion with small peripheral nodules present on MR imaging. Perfusion-weighted MR imaging revealed low relative cerebral blood volume within the calcified lesion and peripheral hyperemia. Single-voxel proton MR spectroscopy with an echo time of 135 milliseconds was normal.
Assuntos
Neoplasias Encefálicas/diagnóstico , Infecções Parasitárias do Sistema Nervoso Central/diagnóstico , Equinococose/diagnóstico , Echinococcus multilocularis , Imageamento por Ressonância Magnética , Doenças Talâmicas/diagnóstico , Tomografia Computadorizada por Raios X , Adulto , Animais , Edema Encefálico/diagnóstico , Calcinose/diagnóstico , Diagnóstico Diferencial , Equinococose Hepática/diagnóstico , Feminino , Humanos , Tálamo/patologiaRESUMO
Se reporta un caso excepcional de hidatidosis ovárica en una paciente joven, con esterilidad primaria. Se evalúan los métodos de diagnóstico, el tratamiento, la evolución clínica y el posible efecto en la fertilidad.
Assuntos
Adulto , Humanos , Feminino , Equinococose/complicações , Equinococose/diagnóstico , Equinococose/tratamento farmacológico , Infertilidade Feminina/parasitologia , Cistos Ovarianos/parasitologia , Cistos Ovarianos/patologia , Albendazol/uso terapêutico , Evolução Clínica , Dor Pélvica/parasitologia , Mebendazol/uso terapêutico , Ovário/patologiaRESUMO
An extremely rare case of a thalamic hydatid cyst is presented and the literature is reviewed. A right thalamic hydatid cyst without rim enhancement or perifocal edema was detected by computed tomography and magnetic resonance. This lesion was extirpated successfully with intact contents via contralateral transcallosal approach. To our knowledge, this is the second hydatid cyst of the thalamus, an unusual location, and the first hydatid cyst to be removed completely with intact contents reported in the literature.
Assuntos
Equinococose/cirurgia , Tálamo/cirurgia , Adolescente , Animais , Equinococose/diagnóstico , Echinococcus/isolamento & purificação , Humanos , Masculino , Procedimentos Neurocirúrgicos/métodos , Tálamo/patologiaRESUMO
Siendo la hidatidosis una enfermedad que cursa en forma asintomática durante gran parte de su evolución, el diagnóstico se plantea en el control ecográfico rutinario de las embarazadas, las cuales rara vez reportan síntomas. A través de un protocolo prospectivo de tratamiento de la hidatidosis en la embarazada, se intervinieron quirúrgicamente en nuestro servicio a 4 embarazadas durante el período abril de 1996, mayo de 1997. Las pacientes tenían 21, 41, 25, y 32 años de edad, su diagnóstico fue confirmado mediante ecografía abdominal y determinación de inmunoglobulinas específicas. Se les sometió a tratamiento quirúrgico a las 26, 38, 14 y 28 semanas, respectivamente, efectuándose quistectomía total y/o subtotal en todas sus lesiones. Todas las pacientes presentaban quistes fértiles. La evolución postoperatoria fue satisfactoria, sin complicaciones. En todos los casos se obtuvo finalmente recién nacidos de término sin complicaciones
Assuntos
Humanos , Feminino , Gravidez , Adulto , Equinococose/cirurgia , Complicações na Gravidez/cirurgia , Evolução Clínica , Equinococose/diagnóstico , Imunoglobulina E , Imunoglobulina G , Imunoglobulinas/uso terapêutico , Complicações na Gravidez/diagnóstico , Resultado da Gravidez , Procedimentos Cirúrgicos OperatóriosRESUMO
La hidatidosis constituye una zoonosis endémica en la IX Región de Chile.Esto, trae como consecuencia que se produzcan hechos considerados como rarezas dentro de la práctica clínica como la asociación de hidatidosis y embarazo. Se presentan 3 pacientes embarazadas portadoras de hidatidosis abdominal, intervenidas quirúrgicamente en nuestro servicio durante el período abril-diciembre de 1996. El diagnóstico fue confirmado mediante ecotomografía abdominal y determinación de inmunoglobulinas específicas. Se les sometió a cirugía a las 26, 38 y 14 semanas respectivamente. Todas las pacientes presentaban quistes fértiles. La evolución postoperatoria fue satisfactoria. En los dos primeros casos la interrupción del embarazo fue electiva mediante operación cesárea, con recién nacidos de término sin complicaciones. Ambas pacientes recibieron quimioterapia complementaria. El último caso, con una evolución postoperatoria correcta, cursa su embarazo en forma fisiológica. Las placentas sometidas a estudio histopatológico no demostraron evidencias de infestación con equinoccocus granulosus. Se presenta una serie de casos consecutivos de embarazadas con EH tratadas en forma agresiva. Creemos que esta conducta es plenamente justificada, dado los graves riesgos implícitos para el binomio madre-hijo
Assuntos
Humanos , Feminino , Gravidez , Recém-Nascido , Adulto , Equinococose/diagnóstico , Complicações Infecciosas na Gravidez/diagnóstico , Albendazol/uso terapêutico , Cesárea , Evolução Clínica , Equinococose/tratamento farmacológico , Equinococose/cirurgia , Placenta/patologia , Complicações Infecciosas na Gravidez/tratamento farmacológico , Complicações Infecciosas na Gravidez/cirurgia , UltrassonografiaRESUMO
A case of a 63 years old woman with splenic hydatidosis without other complications is treated with splenectomy, previous esterilization of the cyst with saline solution (30 percent)
Assuntos
Humanos , Feminino , Pessoa de Meia-Idade , Equinococose/diagnóstico , Baço/fisiopatologia , Evolução Clínica , Equinococose/cirurgia , Cloreto de Sódio/uso terapêutico , Baço , EsplenectomiaRESUMO
Se relata y comenta la experiencia con 6 casos clínicos de hidatidosis cerebral por Echinococcus granulosus operados en temuco, IX Región de Chile, ocurridos entre 1980 y 1991. Se estima una prevalencia de 0,54 casos anuales para 800,000 hbts y entre 0,67 y 0,54 por ciento de hidatidosis cerebral en la región. Los casos son 5 de sexo femenino y 1 masculino con edades entre 3 y 34 años. Fallecen los 3 operados previo a la incorporaciónde la TAC como recurso diagnóstico (1987) y 3 operados post incorporación de la TAC mejoran y sobreviven gracias a un diagnóstico más certero y oportuno. En el tratamiento quirúrgico practicamos el "Parto del Quiste" que consiste en la apertura de la adventicia en forma amplia, de modo que la prolígera intacta con su contenido líquido caigan por gravedad al girar el paciente
Assuntos
Humanos , Masculino , Feminino , Pré-Escolar , Adolescente , Adulto , Doenças do Sistema Nervoso Central/parasitologia , Equinococose/epidemiologia , Procedimentos Cirúrgicos Operatórios , Angiografia Cerebral , Sintomatologia , Prevalência , Mortalidade , Equinococose/cirurgia , Equinococose/diagnóstico , Prognóstico , Tomografia Computadorizada por Raios XRESUMO
KIE: A hypothetical case is presented involving the problem of obtaining informed consent for participation in a study of the distribution of a tapeworm disease in a North African country. Ekunkwe, from the College of Medicine at the University of Lagos, describes how the experiment is likely to be misperceived by potential participants. Given that the proposed study is a relatively safe and routine one, however, he suggests that the investigator proceed as honestly as possible on the basis of "uninformed consent." Kessler, from the University of Maryland School of Medicine, addresses the question whether different standards of informed consent are appropriate in different cultural settings. He concludes that the elements of free and informed consent are the same regardless of setting and that the investigator must find ways to enter the belief system of his subjects to ensure valid consent.^ieng