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Métodos Terapêuticos e Terapias MTCI
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1.
Microsc Res Tech ; 76(7): 704-13, 2013 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-23630046

RESUMO

This study evaluated the synergy of professional acidulated fluoride gel (APF) or fluoridated dentifrice application combined with Er,Cr:YSGG laser irradiation on the formation of CaF2 -like products (CaF2 ), in vitro. Thus, 272 bovine enamel slabs were randomly distributed among eight groups: G1: untreated enamel; G2: treated with fluoridated dentifrice (NaF, 1,100 µgF/g); G3: treated with acidulated phosphate fluoride gel (APF, 1.23% F(-) ); G4: irradiated with Er,Cr:YSGG laser at 8.5 J/cm(2) ; G5 and G6: combination of pre-irradiation with Er,Cr:YSGG followed by dentifrice or APF application, respectively; G7: combination of dentifrice application followed by Er,Cr:YSGG irradiation; G8: combination of APF application followed by Er,Cr:YSGG irradiation. After treatments, samples were evaluated by scanning electron microscopy, and the content of CaF2 was determined by an ion specific electrode. Both APF and dentifrice application promoted the formation of CaF2 on enamel, whereas Er,Cr:YSGG irradiation promoted an increase of roughness of the enamel, increasing the surface area. Laser irradiation before fluoridated products increased the content of CaF2 formed when compared to groups that APF or dentifrice were applied isolated. However, the content of CaF2 formed when irradiation was performed after APF or dentifrice was not statically significant when compared to the control groups. In conclusion, Er,Cr:YSGG laser increases the formation of CaF2 on enamel when the irradiation is performed before the application of APF or dentifrice. The association of laser with APF is most promissory for caries prevention because of the higher concentration of CaF2 formation and also the chemical changes promoted by laser irradiation demonstrated in literature.


Assuntos
Fluoreto de Cálcio/metabolismo , Fluoreto de Cálcio/efeitos da radiação , Esmalte Dentário/efeitos dos fármacos , Esmalte Dentário/efeitos da radiação , Dentifrícios/farmacologia , Lasers de Estado Sólido , Terapia com Luz de Baixa Intensidade , Animais , Bovinos , Esmalte Dentário/ultraestrutura , Técnicas In Vitro , Terapia com Luz de Baixa Intensidade/métodos , Microscopia Eletrônica de Varredura , Resultado do Tratamento
2.
J Phys Chem B ; 112(29): 8840-8, 2008 Jul 24.
Artigo em Inglês | MEDLINE | ID: mdl-18588337

RESUMO

Attenuated total reflectance infrared spectroscopy and complementary scanning electron microscopy were applied to analyze the surface structure of enamel apatite exposed to citric acid and to investigate the protective potential of fluorine-containing reagents against citric acid-induced erosion. Enamel and, for comparison, geological hydroxylapatite samples were treated with aqueous solutions of citric acid and sodium fluoride of different concentrations, ranging from 0.01 to 0.5 mol/L for citric acid solutions and from 0.5 to 2.0% for fluoride solutions. The two solutions were applied either simultaneously or consecutively. The citric acid-induced structural modification of apatite increases with the increase in the citric acid concentration and the number of treatments. The application of sodium fluoride alone does not suppress the atomic level changes in apatite exposed to acidic agents. The addition of sodium fluoride to citric acid solutions leads to formation of surface CaF2 and considerably reduces the changes in the apatite P-O-Ca framework. However, the CaF2 globules deposited on the enamel surface seem to be insufficient to prevent the alteration of the apatite structure upon further exposure to acidic agents. No evidence for fluorine-induced recovery of the apatite structure was found.


Assuntos
Cariostáticos/farmacologia , Ácido Cítrico , Esmalte Dentário/química , Durapatita/química , Fluoretos/farmacologia , Fluoreto de Sódio , Erosão Dentária , Cálcio/química , Cálcio/metabolismo , Fluoreto de Cálcio/química , Fluoreto de Cálcio/metabolismo , Esmalte Dentário/metabolismo , Durapatita/metabolismo , Concentração de Íons de Hidrogênio , Microscopia Eletrônica de Varredura , Oxigênio/química , Oxigênio/metabolismo , Fósforo/química , Fósforo/metabolismo , Soluções/química , Espectrofotometria Infravermelho , Erosão Dentária/induzido quimicamente , Erosão Dentária/patologia , Erosão Dentária/prevenção & controle , Água/química
3.
Adv Dent Res ; 8(2): 190-201, 1994 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-7865075

RESUMO

All currently used topical fluoride agents deposit soluble fluoride as calcium fluoride on enamel or in lesions. Calcium fluoride serves as a source of fluoride for the formation of fluorapatite. The latter phase is formed when pH drops in plaque, not during topical application. The potential for calcium fluoride formation should probably be increased in topical fluoride agents. In countries with low caries prevalence, the clinical recommendations for topical fluoride need to be reconsidered. Toothpaste is the basic fluoride regimen recommended for everybody. The need for additional fluoride supplementation depends on caries activity. There is no distinct difference in the caries-preventive effects of concentrated fluoride solutions, gels, or varnishes. Thus, the choice of method depends on costs, convenience, patient acceptance, and safety. The use of fluoride varnishes has proven to be a feasible and safe method of fluoride application. With fluoride varnishes, the amounts of fluoride exposure can be better controlled, and less chair-time is required compared with conventional solutions and gels. No dose-response effect to concentrated fluoride agents is apparent, and the benefit of frequent application is not clearly established. In individuals with the most severe cariogenic challenge, combinations of fluoride and antimicrobials may give better clinical effects than fluoride alone.


Assuntos
Cárie Dentária/prevenção & controle , Fluoretos Tópicos/farmacologia , Fluoretos Tópicos/uso terapêutico , Fluoreto de Cálcio/metabolismo , Cárie Dentária/epidemiologia , Esmalte Dentário/efeitos dos fármacos , Relação Dose-Resposta a Droga , Durapatita/metabolismo , Europa (Continente)/epidemiologia , Fluoretos Tópicos/química , Humanos , Prevalência
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