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1.
Med Phys ; 46(11): 4918-4922, 2019 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-31437308

RESUMO

PURPOSE: The goal of this study was to investigate x-ray beam profiles at various water depths to characterize the two-dimensional x-ray dose distribution, allowing for off-axis and out-of-field radiation dose estimation for a wide range of x-ray beam spectra commonly encountered in fluoroscopically guided interventional procedures. METHODS: A Siemens Artis interventional fluoroscope was operated in a service mode to generate a continuous x-ray beam at fixed x-ray beam spectra, defined by their kVp and the thickness of additional copper filtration. A PTW scanning water tank with a diode detector was used to measure the x-ray beam profiles at several depths in water at various fields of view and x-ray beam spectra, both parallel and perpendicular to the anode-cathode axis direction. RESULTS: X-ray beam profiles, including out-of-field tails, were characterized for a wide range of beam qualities. The anode heel effect was pronounced even at depth, resulting in large dose variations across the x-ray field; this effect was even more definite at large fields of view, at higher kVps, and in the absence of additional copper filtration. CONCLUSIONS: This study investigated and characterized 2D radiation dose deposition in water from x-ray beam spectra commonly used by modern fluoroscopes in interventional procedures. This knowledge can be applied to manual dosimetry calculations or can be used to refine the accuracy of automated dose mapping tools or Monte Carlo simulations of the radiation dose to soft tissue within the x-ray field and to tissue adjacent to the primary beam. Additionally, this study illustrates a substantial reduction of the anode heel effect by using moderate amounts of additional copper filtration to harden the x-ray beam spectrum.


Assuntos
Cobre , Fluoroscopia/métodos , Doses de Radiação , Filtração , Fluoroscopia/instrumentação , Método de Monte Carlo , Radiometria , Raios X
2.
Eur J Radiol ; 110: 105-111, 2019 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-30599845

RESUMO

BACKGROUND: Exposure to high doses of radiation during cardiac interventional procedures is associated with increased rates of cataract and cancer in patients and staff members. Thus, reduction of radiation is recommended by international medical societies. The aim of this study was to evaluate, if the lowest reasonable fluoroscopic acquisition setting for electrophysiological procedures using a novel X-ray detector operated at a minimum detector entrance dose per fluoroscopy pulse is feasible and safe. METHODS: 641 consecutive patients (407 m/234f) underwent ablation procedures at our institution between August 2015 and December 2017. All ablations were performed using an Artis Q.zen X-ray system (Siemens, Germany). The first 308 patients were treated using the conventional dose program ("fluoroscopy zen standard"), from October 2016 until December 2017 another 333 patients underwent ablations using the optimized X-ray dosing program "fluoroscopy zen ULD". For the standard program fluoroscopy dose was set to 18nGy/f, for the minimized dosing program the dose was set to 6nGy/pulse and could be increased to 10 or 15 nGy/pulse manually. RESULTS: A total of 213 AV-node reentry tachycardia (AVNRT), 73 accessory pathways (AP), 71 atrial flutter and 284 atrial fibrillation (AF) ablation procedures were performed. Pulmonary vein isolation was performed using an electroanatomic mapping system (CARTO, Biosense Webster, USA) in 117 or a cryoballoon (Cryocath Medtronic, USA) in 167 patients. Total area dose could be reduced in all groups by a mean of 74.7% (4201.4µGym² vs. 1063.7µGym²), with a relative reduction of 73.1% for left atrial and 78.0% for right sided ablations. Total fluoroscopy time, procedure duration, acute ablation success, recurrence rate and complications remained unchanged. CONCLUSION: Fluoroscopy dose could be significantly reduced using an optimized X-ray dosing program in a novel X-ray detector without increasing total fluoroscopy time and without alterations of the incidence of recurrences or complications.


Assuntos
Arritmias Cardíacas/cirurgia , Fluoroscopia/instrumentação , Feixe Acessório Atrioventricular/cirurgia , Arritmias Cardíacas/diagnóstico por imagem , Fibrilação Atrial/cirurgia , Flutter Atrial/cirurgia , Ablação por Cateter/métodos , Técnicas Eletrofisiológicas Cardíacas/métodos , Estudos de Viabilidade , Feminino , Fluoroscopia/métodos , Alemanha , Frequência Cardíaca/fisiologia , Humanos , Imageamento Tridimensional , Masculino , Pessoa de Meia-Idade , Veias Pulmonares/fisiopatologia , Doses de Radiação , Taquicardia por Reentrada no Nó Atrioventricular/cirurgia , Resultado do Tratamento
3.
Med Phys ; 45(12): 5420-5436, 2018 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-30339271

RESUMO

PURPOSE: Indirect-detection CMOS flat-panel detectors (FPDs) offer fine pixel pitch, fast readout, and low electronic noise in comparison to current a-Si:H FPDs. This work investigates the extent to which these potential advantages affect imaging performance in mobile C-arm fluoroscopy and cone-beam CT (CBCT). METHODS: FPDs based on CMOS (Xineos 3030HS, 0.151 mm pixel pitch) or a-Si:H (PaxScan 3030X, 0.194 mm pixel pitch) sensors were outfitted on equivalent mobile C-arms for fluoroscopy and CBCT. Technical assessment of 2D and 3D imaging performance included measurement of electronic noise, gain, lag, modulation transfer function (MTF), noise-power spectrum (NPS), detective quantum efficiency (DQE), and noise-equivalent quanta (NEQ) in fluoroscopy (with entrance air kerma ranging 5-800 nGy per frame) and cone-beam CT (with weighted CT dose index, CTDIw , ranging 0.08-1 mGy). Image quality was evaluated by clinicians in vascular, orthopaedic, and neurological surgery in realistic interventional scenarios with cadaver subjects emulating a variety of 2D and 3D imaging tasks. RESULTS: The CMOS FPD exhibited ~2-3× lower electronic noise and ~7× lower image lag than the a-Si:H FPD. The 2D (projection) DQE was superior for CMOS at ≤50 nGy per frame, especially at high spatial frequencies (~2% improvement at 0.5 mm-1 and ≥50% improvement at 2.3 mm-1 ) and was somewhat inferior at moderate-high doses (up to 18% lower DQE for CMOS at 0.5 mm-1 ). For smooth CBCT reconstructions (low-frequency imaging tasks), CMOS exhibited ~10%-20% higher NEQ (at 0.1-0.5 mm-1 ) at the lowest dose levels (CTDIw ≤0.1 mGy), while the a-Si:H system yielded slightly (~5%) improved NEQ (at 0.1-0.5 lp/mm) at higher dose levels (CTDIw ≥0.6 mGy). For sharp CBCT reconstructions (high-frequency imaging tasks), NEQ was ~32% higher above 1 mm-1 for the CMOS system at mid-high-dose levels and ≥75% higher at the lowest dose levels (CTDIw ≤0.1 mGy). Observer assessment of 2D and 3D cadaver images corroborated the objective metrics with respect to a variety of pertinent interventional imaging tasks. CONCLUSION: Measurements of image noise, spatial resolution, DQE, and NEQ indicate improved low-dose performance for the CMOS-based system, particularly at lower doses and higher spatial frequencies. Assessment in realistic imaging scenarios confirmed improved visibility of fine details in low-dose fluoroscopy and CBCT. The results quantitate the extent to which CMOS detectors improve mobile C-arm imaging performance, especially in 2D and 3D imaging scenarios involving high-resolution tasks and low-dose conditions.


Assuntos
Tomografia Computadorizada de Feixe Cônico/instrumentação , Fluoroscopia/instrumentação , Metais/química , Óxidos/química , Semicondutores , Desenho de Equipamento , Humanos , Imageamento Tridimensional , Razão Sinal-Ruído
4.
BMC Musculoskelet Disord ; 18(1): 479, 2017 Nov 21.
Artigo em Inglês | MEDLINE | ID: mdl-29162080

RESUMO

BACKGROUND: "Advanced Core Decompression" (ACD) is a new technique for treatment of osteonecrosis of the femoral head (ONFH) that includes removal of the necrotic tissue using a percutaneous expandable reamer followed by refilling of the drill hole and the defect with an injectable, hard-setting, composite calcium sulphate (CaSO4)-calcium phosphate (CaPO4) bone graft substitute. As autologous bone has been shown to be superior to all other types of bone grafts, the aim of the study is to present and evaluate a modified technique of ACD with impaction of autologous bone derived from the femoral neck into the necrotic defect. METHODS: A cohort of patients with an average follow-up of 30.06 months (minimum 12 months) was evaluated for potential collapse of the femoral head and any reasons that led to replacement of the operated hip. Only patients in stages 2a to 2c according to the Steinberg classification were included in the study. RESULTS: In 75.9% the treatment was successful with no collapse of the femoral head or conversion to a total hip replacement. Analysis of the results of the different subgroups showed that the success rate was 100% for stage 2a lesions and 84.6% respectively 61.5% for stages 2b and 2c lesions. CONCLUSIONS: Previous studies with a comparable follow-up reported less favourable results for ACD without autologous bone. Especially in stages 2b and 2c the additional use of autologous bone has a positive effect. In comparison to other hip-preserving techniques, the modified ACD technique is a very promising and minimally invasive method for treatment of ONFH. TRIAL REGISTRATION: German clinical trials register ( DRKS00011269 , retrospectively registered).


Assuntos
Substitutos Ósseos/efeitos adversos , Transplante Ósseo/métodos , Descompressão Cirúrgica/métodos , Necrose da Cabeça do Fêmur/cirurgia , Colo do Fêmur/transplante , Adulto , Artroplastia de Quadril/efeitos adversos , Fios Ortopédicos , Fosfatos de Cálcio/efeitos adversos , Sulfato de Cálcio/efeitos adversos , Descompressão Cirúrgica/instrumentação , Feminino , Necrose da Cabeça do Fêmur/patologia , Fluoroscopia/instrumentação , Fluoroscopia/métodos , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Tratamentos com Preservação do Órgão/métodos , Estudos Prospectivos , Falha de Prótese , Transplante Autólogo/métodos , Resultado do Tratamento , Adulto Jovem
5.
BMC Med Imaging ; 16: 30, 2016 Apr 19.
Artigo em Inglês | MEDLINE | ID: mdl-27094510

RESUMO

BACKGROUND: Mobile 3D fluoroscopes have become increasingly available in neurosurgical operating rooms. In this series, the image quality and value of intraoperative 3D fluoroscopy with intravenous contrast agent for the evaluation of aneurysm occlusion and vessel patency after clip placement was assessed in patients who underwent surgery for intracranial aneurysms. MATERIALS AND METHODS: Twelve patients were included in this retrospective analysis. Prior to surgery, a 360° rotational fluoroscopy scan was performed without contrast agent followed by another scan with 50 ml of intravenous iodine contrast agent. The image files of both scans were transferred to an Apple PowerMac® workstation, subtracted and reconstructed using OsiriX® free software. The procedure was repeated after clip placement. Both image sets were compared for assessment of aneurysm occlusion and vessel patency. RESULTS: Image acquisition and contrast administration caused no adverse effects. Image quality was sufficient to follow the patency of the vessels distal to the clip. Metal artifacts reduce the assessability of the immediate vicinity of the clip. Precise image subtraction and post-processing can reduce metal artifacts and make the clip-site assessable and depict larger neck-remnants. CONCLUSION: This technique quickly supplies images at adequate quality to evaluate distal vessel patency after aneurysm clipping. Significant aneurysm remnants may be depicted as well. As it does not require visual control of all vessels that are supposed to be evaluated intraoperatively, this technique may be complementary to other intraoperative tools like indocyanine green videoangiography and micro-Doppler, especially for the assessment of larger aneurysms. At the momentary state of this technology, it cannot replace postoperative conventional angiography. However, 3D fluoroscopy and image post-processing are young technologies. Further technical developments are likely to result in improved image quality.


Assuntos
Interpretação de Imagem Assistida por Computador/métodos , Imageamento Tridimensional/métodos , Aneurisma Intracraniano/cirurgia , Procedimentos Neurocirúrgicos/métodos , Meios de Contraste/administração & dosagem , Estudos de Viabilidade , Fluoroscopia/instrumentação , Humanos , Interpretação de Imagem Assistida por Computador/normas , Procedimentos Neurocirúrgicos/instrumentação , Estudos Retrospectivos , Software
6.
Sci Rep ; 5: 12842, 2015 Aug 04.
Artigo em Inglês | MEDLINE | ID: mdl-26239953

RESUMO

Visualizing the movement of angiocatheters during endovascular interventions is typically accomplished using x-ray fluoroscopy. There are many potential advantages to developing magnetic resonance imaging-based approaches that will allow three-dimensional imaging of the tissue/vasculature interface while monitoring other physiologically-relevant criteria, without exposing the patient or clinician team to ionizing radiation. Here we introduce a proof-of-concept development of a magnetic resonance imaging-guided catheter tracking method that utilizes hyperpolarized silicon particles. The increased signal of the silicon particles is generated via low-temperature, solid-state dynamic nuclear polarization, and the particles retain their enhanced signal for ≥ 40 minutes--allowing imaging experiments over extended time durations. The particles are affixed to the tip of standard medical-grade catheters and are used to track passage under set distal and temporal points in phantoms and live mouse models. With continued development, this method has the potential to supplement x-ray fluoroscopy and other MRI-guided catheter tracking methods as a zero-background, positive contrast agent that does not require ionizing radiation.


Assuntos
Meios de Contraste/química , Fluoroscopia/métodos , Imageamento por Ressonância Magnética/métodos , Silício/química , Animais , Fluoroscopia/instrumentação , Humanos , Imageamento por Ressonância Magnética/instrumentação , Masculino , Camundongos , Camundongos Transgênicos , Imagens de Fantasmas , Fatores de Tempo , Cateteres Urinários , Dispositivos de Acesso Vascular
7.
Rofo ; 183(7): 641-4, 2011 Jul.
Artigo em Alemão | MEDLINE | ID: mdl-21391175

RESUMO

PURPOSE: To determine the practicability and outcome of fluoroscopic-guided primary one-step treatment of percutaneous gastrostomy (PG) with the system Freka® Gastro Tube (Fresenius Kabi, Germany). MATERIALS AND METHODS: In 39 patients (mean age 62.7 ± 12.0 years), primary PG was performed based on clinical indication from August 2009 to April 2010. The intervention was performed by an experienced radiologist under aseptic conditions by direct puncture with Freka® Gastro Tube under fluoroscopic guidance. The clinical data and outcome as well as any complications originated from the electronic archive of the University Medical Center Hamburg-Eppendorf. RESULTS: The intervention was technically successful in all 39 patients. Within the mean follow-up time of 155.3 ± 73.6 days, 29 patients (74.4 %) did not experience complications. 10 patients (25.6 %) had to be revised. Complications manifested after a mean of 135.6 ± 61.2 days and mainly corresponded to accidental dislocation (50 %). One patient had to be surgically revised under suspicion of a malpositioned tube and suspected intestinal perforation. Clinically relevant wound infections were not detected. The total costs per patient were 553.17 € for our single-step treatment (OPS 5 - 431.x) vs. 963.69 € (OPS 5 - 431.x and OPS 8 - 123.0) for the recommended two-step treatment. CONCLUSION: Fluoroscopic-guided primary single-step treatment with Freka® Gastro Tube system is feasible and not associated with an increased complication rate when compared to published literature applying a two-step treatment approach. Material costs as well as human and time resources could be significantly reduced using the single-step treatment.


Assuntos
Cateteres de Demora , Fluoroscopia/instrumentação , Gastrostomia/instrumentação , Procedimentos Cirúrgicos Minimamente Invasivos/instrumentação , Idoso , Cateteres de Demora/economia , Custos e Análise de Custo , Desenho de Equipamento , Feminino , Fluoroscopia/economia , Seguimentos , Gastrostomia/economia , Humanos , Masculino , Pessoa de Meia-Idade , Procedimentos Cirúrgicos Minimamente Invasivos/economia , Programas Nacionais de Saúde/economia , Reoperação/economia
8.
J Interv Card Electrophysiol ; 30(3): 233-40, 2011 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-21253840

RESUMO

PURPOSE: Pulmonary vein antrum isolation (PVAI) guided by intracardiac echocardiography and a roaming circular mapping catheter is an effective treatment modality for atrial fibrillation. Unfortunately, the complexity of this technique leads to long procedure times and high fluoroscopy exposure. This study examined the effect of two different mapping systems on the procedural characteristics and clinical outcomes of PVAI for atrial fibrillation. METHODS: Referred patients underwent PVAI using a magnetic-based 3-dimensional (3-D) mapping (CARTO® System; group 1), a current-based system (EnSite NavX™; group 2), or fluoroscopy without 3-D mapping (group 3) between February 2004 and November 2009. RESULTS: Data were analyzed from 71 patients in group 1, 165 patients in group 2, and 197 patients in group 3. Baseline characteristics and measured long-term outcomes did not differ between the groups. Although patients in group 1 were more likely to undergo a concurrent flutter ablation (P = 0.01), they had significantly shorter procedure time, fluoroscopy time, and radiofrequency energy delivery time compared with group 2 and 3 patients. No difference was detected among the groups with respect to recurrence, mean time to recurrence, or number of PVAI procedures. CONCLUSIONS: Use of a magnetic-based 3-D mapping system, which allows precise spatial localization of the ablation catheter, was associated with significantly lower procedure time, fluoroscopy duration, and radiofrequency energy delivery time during catheter ablation for atrial fibrillation compared with a current-based system and ablation performed without 3-D mapping, although measured short- and long-term clinical outcomes were similar.


Assuntos
Fibrilação Atrial/cirurgia , Ablação por Cateter/métodos , Técnicas Eletrofisiológicas Cardíacas/instrumentação , Fluoroscopia/instrumentação , Veias Pulmonares/cirurgia , Cirurgia Assistida por Computador/instrumentação , Fibrilação Atrial/fisiopatologia , Distribuição de Qui-Quadrado , Eletrocardiografia , Feminino , Humanos , Imageamento Tridimensional/instrumentação , Masculino , Pessoa de Meia-Idade , Recidiva , Estudos Retrospectivos , Resultado do Tratamento
9.
Spine (Phila Pa 1976) ; 35(21): E1126-32, 2010 Oct 01.
Artigo em Inglês | MEDLINE | ID: mdl-20838268

RESUMO

STUDY DESIGN: Development of a patient-mount navigated intervention (PaMNI) system for spinal diseases. An in vivo clinical human trial was conducted to validate this system. OBJECTIVE: To verify the feasibility of the PaMNI system with the clinical trial on percutaneous pulsed radiofrequency stimulation of dorsal root ganglion (PRF-DRG). SUMMARY OF BACKGROUND DATA: Two major image guiding techniques, i.e., computed tomography (CT)-guided and fluoro-guided, were used for spinal intervention. The CT-guided technique provides high spatial resolution, and is claimed to be more accurate than the fluoro-guided technique. Nevertheless, the CT-guided intervention usually reaches higher radiograph exposure than the fluoro-guided counterpart. Some navigated intervention systems were developed to reduce the radiation of CT-guided intervention. Nevertheless, these systems were not popularly used due to the longer operation time, a new protocol for surgeons, and the availability of such a system. METHODS: The PaMNI system includes 3 components, i.e., a patient-mount miniature tracking unit, an auto-registered reference frame unit, and a user-friendly image processing unit. The PRF-DRG treatment was conducted to find the clinical feasibility of this system. RESULTS: The in vivo clinical trial showed that the accuracy, visual analog scale evaluation after surgery, and radiograph exposure of the PaMNI-guided technique are comparable to the one of conventional fluoro-guided technique, while the operation time is increased by 5 minutes. CONCLUSION: Combining the virtues of fluoroscopy and CT-guided techniques, our navigation system is operated like a virtual fluoroscopy with augmented CT images. This system elevates the performance of CT-guided intervention and reduces surgeons' radiation exposure risk to a minimum, while keeping low radiation dose to patients like its fluoro-guided counterpart. The clinical trial of PRF-DRG treatment showed the clinical feasibility and efficacy of this system.


Assuntos
Fluoroscopia/métodos , Gânglios Espinais/cirurgia , Dor Lombar/cirurgia , Neuronavegação/métodos , Tomografia Computadorizada por Raios X/métodos , Estimulação Elétrica Nervosa Transcutânea/métodos , Adulto , Idoso , Feminino , Fluoroscopia/instrumentação , Fluoroscopia/tendências , Gânglios Espinais/diagnóstico por imagem , Gânglios Espinais/fisiologia , Humanos , Dor Lombar/fisiopatologia , Masculino , Pessoa de Meia-Idade , Neuronavegação/instrumentação , Tomografia Computadorizada por Raios X/instrumentação , Tomografia Computadorizada por Raios X/tendências , Estimulação Elétrica Nervosa Transcutânea/instrumentação
10.
Eur Spine J ; 18(12): 1986-8, 2009 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-19575242
11.
Dysphagia ; 23(3): 302-9, 2008 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-18437464

RESUMO

Neuromuscular electrical stimulation (NMES) technique is a dual-channel electrotherapy system designed specifically for the treatment of pharyngeal dysfunction. The purpose of this study was to evaluate and compare the outcome of NMES versus traditional swallowing therapy (TT) in stroke patients. Three European swallowing centers participated in this randomized trial. Twenty-five patients (16 men and 9 women) were included. Twelve patients were randomized for NMES and 13 for TT. Mean age was 70 years for the NMES group and 71 years for the TT group. Inclusion criteria were (1) patients 50-80 years old with cerebrovascular disease (stroke) for more than 3 months before the study, (2) only patients with hemispheric stroke, (3) no brainstem involvement, (4) ability to swallow, and (5) ability to communicate. Pre- and post-trial measurements were videoradiographic swallowing evaluation, nutritional status, oral motor function test, and a visual analog scale (VAS) for self-evaluation of complaints. All subjects received 15 therapy sessions. Statistically significant positive therapy effects for both NMES and TT combined were found, but there was no statistically significant difference in therapy effect between the groups. The correlations between measurements were low. The patient's subjective experience of improvement had low correlation with the outcome from the objective evaluation.


Assuntos
Transtornos de Deglutição/fisiopatologia , Doenças Faríngeas/fisiopatologia , Acidente Vascular Cerebral/fisiopatologia , Idoso , Idoso de 80 Anos ou mais , Deglutição , Transtornos de Deglutição/etiologia , Transtornos de Deglutição/terapia , Estimulação Elétrica , Feminino , Fluoroscopia/instrumentação , Humanos , Masculino , Pessoa de Meia-Idade , Atividade Motora , Avaliação Nutricional , Medição da Dor , Doenças Faríngeas/etiologia , Acidente Vascular Cerebral/complicações
12.
Heart Rhythm ; 5(4): 526-35, 2008 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-18362019

RESUMO

BACKGROUND: Three-dimensional virtual anatomic navigation is increasingly used during mapping and ablation of complex arrhythmias. NavX Fusion software aims to mold the virtual anatomy to the patient's computed tomography (CT) image; however, the accuracy and clinical usefulness of this system have not been reported. OBJECTIVE: The purpose of this study was to assess the accuracy and describe the initial experience of CT image integration using NavX Fusion for atrial fibrillation ablation. METHODS: This study consisted of 55 consecutive patients undergoing atrial fibrillation ablation using NavX Fusion navigation. Left atrial NavX geometries were compared to a corresponding CT for geometric match. Geometric match, expressed as the difference in millimeters between CT and NavX geometry, was calculated for the original geometry (GEO-1), field scaled and primary fused geometry (GEO-2), and final secondary fused geometry (GEO-3). Navigational accuracy was assessed by moving the catheter to 10 discrete anatomic sites and determining the distance between the catheter tip and the closest GEO-2, GEO-3, and CT surface. Fusion integration time and procedural and fluoroscopic durations were recorded to assess clinical usefulness. RESULTS: GEO-1, GEO-2 and GEO-3 were associated with CT-GEO errors of 6.6+/-2.8 mm, 4.1+/-0.7 mm, 1.9+/-0.4 mm, respectively. Navigational accuracy was not significantly different for GEO-2, GEO-3, and CT at 3.4+/-1.6 mm to any surface. A significant (P < or =.001) inverse curvilinear relationship was present between case number and the time required for image integration (r(2) = 0.35) and the fluoroscopic time normalized for procedural duration (r(2) = 0.18). CONCLUSION: Image integration using the NavX Fusion software is highly accurate and is associated with a progressive reduction in fluoroscopic time relative to procedural duration.


Assuntos
Fibrilação Atrial/terapia , Mapeamento Potencial de Superfície Corporal , Ablação por Cateter/instrumentação , Técnicas Eletrofisiológicas Cardíacas/instrumentação , Imageamento Tridimensional , Software , Tomografia Computadorizada por Raios X , Potenciais de Ação , Estimulação Cardíaca Artificial , Ablação por Cateter/métodos , Técnicas Eletrofisiológicas Cardíacas/métodos , Feminino , Fluoroscopia/instrumentação , Sistema de Condução Cardíaco/fisiopatologia , Humanos , Imageamento Tridimensional/métodos , Masculino , Pessoa de Meia-Idade , Fatores de Tempo , Tomografia Computadorizada por Raios X/métodos
13.
Neurosurgery ; 60(4 Suppl 2): 352-60; discussion 360-1, 2007 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-17415174

RESUMO

OBJECTIVE: To assess the feasibility of a hybrid imaging setup combining x-ray and magnetic resonance imaging (MRI) in the setting of both stereotactic and functional neurosurgery. METHODS: A combined x-ray and MRI scanning facility with a trolley system for a fast patient transfer between both modalities was installed in a neurosurgical setting. A registration algorithm for fusion of MRI scans and x-ray images was derived for augmentation of fluoroscopic x-ray projection images with MRI scan data, such as anatomic structures and planned probe trajectories. Phantom measurements were obtained between both modalities for estimation of registration accuracy. Practical application of our system in stereotactic and functional neurosurgery was tested in brachytherapy, deep brain stimulation, and motor cortex stimulation. RESULTS: Phantom measurements yielded a mean spatial deviation of 0.7 +/- 0.3 mm with a maximum deviation of 1.1 mm for MRI scans versus x-rays. Augmentation of x-ray images with MRI scan data allowed intraoperative verification of the planned trajectory and target in three types of neurosurgical procedures: positioning iodine seeds in brachytherapy in one case with cerebellar metastasis, placement of electrodes for deep brain stimulation in two cases of advanced Parkinson's disease, and placement of an epidural grid for motor cortex stimulation in two cases of intractable pain. CONCLUSION: Combined x-ray and MRI-guided stereotactic and functional neurosurgery is feasible. Augmentation of x-ray projection images with MRI scan data, such as planned probe trajectories and MRI scan segmented anatomic structures may be beneficial for probe guidance in stereotactic and functional neurosurgery.


Assuntos
Neoplasias Encefálicas/radioterapia , Fluoroscopia/instrumentação , Imageamento por Ressonância Magnética/instrumentação , Procedimentos Neurocirúrgicos/instrumentação , Doença de Parkinson/terapia , Técnicas Estereotáxicas/instrumentação , Braquiterapia , Neoplasias Encefálicas/secundário , Neoplasias Encefálicas/cirurgia , Calibragem , Estimulação Encefálica Profunda/instrumentação , Estimulação Encefálica Profunda/métodos , Estudos de Viabilidade , Humanos , Modelos Teóricos , Córtex Motor/cirurgia , Procedimentos Neurocirúrgicos/métodos , Dor Intratável/cirurgia , Dor Intratável/terapia , Doença de Parkinson/cirurgia , Imagens de Fantasmas
14.
J Surg Oncol ; 95(7): 582-6, 2007 Jun 01.
Artigo em Inglês | MEDLINE | ID: mdl-17230542

RESUMO

BACKGROUND: To evaluate the efficacy and acceptability of the Port-A-Cath (PAC) insertion method with (conventional group as II) and without (modified group as I) the aid of intraoperative fluoroscopy or other localizing devices. METHODS: A total of 158 women with various kinds of gynecological cancers warranting PAC insertion (n = 86 in group I and n = 72 in group II, respectively) were evaluated. Data for analyses included patient age, main disease, dislocation site, surgical time, complications, and catheter outcome. RESULTS: There was no statistical difference between the two groups in terms of age, main disease, complications, and the experiencing of patent catheters. However, appropriate positioning (100% in group I, and 82% in group II) in the superior vena cava (SVC) showed statistical differences between the two groups (P = 0.001). In addition, the surgical time in group I was statistically shorter than that in group II (P < 0.001). CONCLUSIONS: The modified method for inserting the PAC offered the following benefits: including avoiding X-ray exposure for both the operator and the patient, defining the appropriate position in the SVC, and less surgical time.


Assuntos
Anestesia Local , Cateterismo Venoso Central/métodos , Cateterismo Venoso Central/normas , Anestésicos Locais , Cateterismo Venoso Central/economia , Cateterismo Venoso Central/instrumentação , Cateteres de Demora/efeitos adversos , Cateteres de Demora/economia , Análise Custo-Benefício , Desenho de Equipamento , Estudos de Avaliação como Assunto , Feminino , Fluoroscopia/instrumentação , Neoplasias dos Genitais Femininos/cirurgia , Humanos , Infusões Intravenosas , Cuidados Intraoperatórios , Lidocaína , Pessoa de Meia-Idade
15.
Cardiovasc Intervent Radiol ; 30(2): 169-76, 2007.
Artigo em Inglês | MEDLINE | ID: mdl-17216374

RESUMO

PURPOSE: To assess the influence of physician-selectable equipment variables on the potential radiation dose reductions during cardiac catheterization examinations using modern imaging equipment. MATERIALS: A modern bi-plane angiography unit with flat-panel image receptors was used. Patients were simulated with 15-30 cm of acrylic plastic. The variables studied were: patient thickness, fluoroscopy pulse rates, record mode frame rates, image receptor field-of-view (FoV), automatic dose control (ADC) mode, SID/SSD geometry setting, automatic collimation, automatic positioning, and others. RESULTS: Patient radiation doses double for every additional 3.5-4.5 cm of soft tissue. The dose is directly related to the imaging frame rate; a decrease from 30 pps to 15 pps reduces the dose by about 50%. The dose is related to [(FoV)(-N )] where 2.0 < N < 3.0. Suboptimal positioning of the patient can nearly double the dose. The ADC system provides three selections that can vary the radiation level by 50%. For pediatric studies (2-5 years old), the selection of equipment variables can result in entrance radiation doses that range between 6 and 60 cGy for diagnostic cases and between 15 and 140 cGy for interventional cases. For adult studies, the equipment variables can produce entrance radiation doses that range between 13 and 130 cGy for diagnostic cases and between 30 and 400 cGy for interventional cases. CONCLUSIONS: Overall dose reductions of 70-90% can be achieved with pediatric patients and about 90% with adult patients solely through optimal selection of equipment variables.


Assuntos
Cateterismo Cardíaco , Fluoroscopia/métodos , Coração/efeitos da radiação , Resinas Acrílicas , Adulto , Cateterismo Cardíaco/métodos , Ablação por Cateter , Pré-Escolar , Angiografia Coronária , Técnicas Eletrofisiológicas Cardíacas , Desenho de Equipamento , Análise de Falha de Equipamento , Fluoroscopia/instrumentação , Cardiopatias/diagnóstico por imagem , Cardiopatias/cirurgia , Humanos , Imagens de Fantasmas , Radiografia Intervencionista , Resultado do Tratamento
16.
Dysphagia ; 21(4): 243-53, 2006 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-17216386

RESUMO

This study compares the outcomes using VitalStim therapy to outcomes using traditional swallowing therapy for deglutition disorders. Twenty-two patients had an initial and a followup videofluoroscopic swallowing study or fiberoptic endoscopic evaluation of swallowing and were divided into an experimental group that received VitalStim treatments and a control group that received traditional swallowing therapy. Outcomes were analyzed for changes in oral and pharyngeal phase dysphagia severity, dietary consistency restrictions, and progression from nonoral to oral intake. Results of chi(2) analysis showed no statistically significant difference in outcomes between the experimental and control groups.


Assuntos
Transtornos de Deglutição/diagnóstico , Transtornos de Deglutição/terapia , Otolaringologia/métodos , Adolescente , Idoso , Idoso de 80 Anos ou mais , Feminino , Fluoroscopia/instrumentação , Humanos , Masculino , Pessoa de Meia-Idade , Boca/fisiologia , Faringe/fisiologia , Resultado do Tratamento , Gravação de Videoteipe
18.
Br J Radiol ; 77(922): 864-8, 2004 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-15482999

RESUMO

A study of patient doses for barium enema and meal examinations has been carried out for hospitals in the West of Scotland to assess the impact of dose reduction facilities on new X-ray equipment. Dose-area product (DAP) information has been collected on examinations for groups of patients at 20 hospitals and results reviewed together with data on equipment performance measurements. Median DAPs for barium enemas and meals were 15.7 Gy cm(2) and 4.8 Gy cm(2), respectively, and effective doses estimated from the results are 3.5+/-0.7 mSv and 1.5+/-0.5 mSv, respectively. These doses are lower than those reported in earlier studies and in previous surveys in the West of Scotland. The reduction in dose is linked primarily to the low dose facilities available on newer X-ray equipment, such as low dose pulsed fluoroscopy, digital imaging facilities and use of copper filtration. Use of the image intensifier for decubitus images on C-arm units employed for barium enemas also gives a significantly lower dose. Equipment with copper filtration had the lowest doses. The reduction in effective dose will be significantly less than the reduction in DAP for units in which a copper filter is included and the adoption of lower diagnostic reference levels is proposed for units with this facility. It is important that the operators are aware of the low dose imaging options on their equipment in order that techniques can be fully optimized.


Assuntos
Sulfato de Bário/administração & dosagem , Enema/métodos , Radiologia/instrumentação , Fluoroscopia/instrumentação , Humanos , Doses de Radiação
19.
Med Phys ; 31(5): 1166-75, 2004 May.
Artigo em Inglês | MEDLINE | ID: mdl-15191306

RESUMO

The imaging performance of an amorphous selenium (a-Se) flat-panel detector for digital fluoroscopy was experimentally evaluated using the spatial frequency dependent modulation transfer function (MTF), noise power spectrum (NPS), and detective quantum efficiency (DQE). These parameters were investigated at beam qualities and exposures within the range typical of gastrointestinal fluoroscopic imaging (approximately 0.1 - 10 microR, 75 kV). The investigation does not take into consideration the detector cover, which in clinical use will lower the DQE measured here by its percent attenuation. The MTF was found to be less than the expected aperture response and the NPS was not white which together indicate presampling blurring. The cause of this blurring was attributed to charge trapping at the interface between two different layers of the a-Se. The effect on the DQE was also consistent with presampling blur, which reduces the aliasing in the NPS and thereby reduces the spatial frequency dependence of the DQE. (The DQE was independent of spatial frequency from 0.12 to 0.73 mm(-1) due to antialiasing of the NPS.) Moreover, the first zero of the measured MTF and the aperture response appeared at the same spatial frequency (6.66 mm(-1) for a pixel of 150 microm). Hence, the geometric fill factor (77%) was increased to an effective fill factor of 99 +/- 1%. A large scale ( approximately 32 pixels) correlation in the noise due to the configuration of the readout electronics caused increased noise power in the gate line NPS at low spatial frequency (< 0.1 mm(-1)). The DQE (f = 0) was exposure independent over a large range of exposures but became exposure dependent at low exposures due to the electronic noise.


Assuntos
Análise de Falha de Equipamento/métodos , Fluoroscopia/instrumentação , Intensificação de Imagem Radiográfica/instrumentação , Interpretação de Imagem Radiográfica Assistida por Computador/instrumentação , Selênio/efeitos da radiação , Transdutores , Desenho de Equipamento , Fluoroscopia/métodos , Imagens de Fantasmas , Intensificação de Imagem Radiográfica/métodos , Interpretação de Imagem Radiográfica Assistida por Computador/métodos , Reprodutibilidade dos Testes , Sensibilidade e Especificidade
20.
Med Phys ; 29(11): 2464-71, 2002 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-12462710

RESUMO

Fluoroscopy is a low dose imaging technique. As such, a very sensitive detector is required to create images of good quality. Present day flat panel active matrix read out systems introduce an amount of noise that inhibits present direct and indirect methods from producing optimal quality images at fluoroscopic exposure rates (0.1-10 microR per frame). The gain of the direct conversion approach using amorphous selenium (a-Se) was investigated to determine whether by increasing the applied electric field, a gain sufficient to overcome the noise limitations of the active matrix could be achieved. Conversion gain and avalanche multiplication in a-Se were investigated as a function of electric field from 10 to 100 V/microm. Our results show a factor of 4 increase in conversion gain is available by increasing electric field from the current standard of 10 V/microm to 100 V/microm. Furthermore, we show that avalanche multiplication can provide an additional gain of up to 25. This increase in signal is sufficient to overcome the noise level encountered in flat panel detectors and permit fully quantum noise limited operation across the whole fluoroscopic range of exposure.


Assuntos
Campos Eletromagnéticos , Fluoroscopia/instrumentação , Intensificação de Imagem Radiográfica/instrumentação , Selênio/efeitos da radiação , Ecrans Intensificadores para Raios X , Desenho de Equipamento , Análise de Falha de Equipamento/instrumentação , Análise de Falha de Equipamento/métodos , Estudos de Viabilidade , Teste de Materiais/instrumentação , Teste de Materiais/métodos , Controle de Qualidade , Intensificação de Imagem Radiográfica/métodos , Reprodutibilidade dos Testes , Sensibilidade e Especificidade , Raios X
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