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1.
Hernia ; 24(6): 1371-1378, 2020 12.
Artigo em Inglês | MEDLINE | ID: mdl-32170456

RESUMO

PURPOSE: Laparoscopic inguinal hernia repair (IHR) may lead to early postoperative pain. Therefore, opioid and non-opioid analgesic agents are often administered in the post-anesthesia care unit (PACU). To reduce the postoperative cumulative need of analgesic medication, as well as to accelerate the physical recovery time, the transversus abdominis plane (TAP) block has recently been studied. The TAP block is a regional anesthesia technique. Even though there is evidence about the efficacy of the block used in procedure such as an open inguinal hernia repair, the evidence regarding its use for the TAPP (transabdominal preperitoneal) technique remains low. We aim to provide more sufficient evidence regarding this topic. METHODS: A monocentric retrospective observational study investigating the effect of the TAP block prior to primary IHR in TAPP technique was conducted. The data of 838 patients who were operated on using this technique from June 2007 to February 2019 were observed. 72 patients were excluded because of insufficient information regarding their analgesic medication protocol. The patients' data were taken from their files. RESULTS: The patients in the TAP block group (n = 364) did not differ statistically significantly compared to the control group (n = 402) in terms of gender, BMI and age. Individuals of the TAP block group experienced less postoperative pain in the PACU (p < 0.001) and received less analgesic medication (morphine, oxycodone, piritramide, acetaminophen; p < 0.001). CONCLUSION: We assume that the TAP block is a sufficient approach to reduce postoperative pain and analgesic medication administration for IHR in TAPP technique.


Assuntos
Músculos Abdominais/efeitos dos fármacos , Amidinas/uso terapêutico , Anestesia Local/métodos , Hérnia Inguinal/tratamento farmacológico , Bloqueio Nervoso/métodos , Músculos Abdominais/cirurgia , Amidinas/farmacologia , Feminino , Hérnia Inguinal/cirurgia , Humanos , Masculino , Estudos Retrospectivos
2.
ACS Nano ; 14(2): 2265-2275, 2020 02 25.
Artigo em Inglês | MEDLINE | ID: mdl-32017535

RESUMO

Biomedical device-associated infection (BAI) is a great challenge in modern clinical medicine. Therefore, developing efficient antibacterial materials is significantly important and meaningful for the improvement of medical treatment and people's health. In the present work, we developed a strategy of surface functionalization for multifunctional antibacterial applications. A functionalized polyurethane (PU, a widely used biomedical material for hernia repairing) surface (PU-Au-PEG) with inherent antifouling and photothermal bactericidal properties was readily prepared based on a near-infrared (NIR)-responsive organic/inorganic hybrid coating which consists of gold nanorods (Au NRs) and polyethylene glycol (PEG). The PU-Au-PEG showed a high efficiency to resist adhesion of bacteria and exhibited effective photothermal bactericidal properties under 808 nm NIR irradiation, especially against multidrug-resistant bacteria. Furthermore, the PU-Au-PEG could inhibit biofilm formation long term. The biocompatibility of PU-Au-PEG was also proved by cytotoxicity and hemolysis tests. The in vivo photothermal antibacterial properties were first verified by a subcutaneous implantation animal model. Then, the anti-infection performance in a clinical scenario was studied with an infected hernia model. The results of animal experiment studies demonstrated excellent in vivo anti-infection performances of PU-Au-PEG. The present work provides a facile and promising approach to develop multifunctional biomedical devices.


Assuntos
Antibacterianos/farmacologia , Incrustação Biológica/prevenção & controle , Hérnia Inguinal/tratamento farmacológico , Staphylococcus aureus Resistente à Meticilina/efeitos dos fármacos , Animais , Antibacterianos/química , Modelos Animais de Doenças , Ouro/química , Ouro/farmacologia , Hérnia Inguinal/microbiologia , Hérnia Inguinal/cirurgia , Nanotubos/química , Tamanho da Partícula , Fototerapia , Polímeros/química , Polímeros/farmacologia , Poliuretanos/química , Poliuretanos/farmacologia , Ratos , Ratos Sprague-Dawley , Propriedades de Superfície
3.
Rev. esp. anestesiol. reanim ; 59(1): 18-24, ene. 2012.
Artigo em Espanhol | IBECS | ID: ibc-97774

RESUMO

Objetivo: Recientemente se ha producido renovado interés sobre la técnica anestésica en la cirugía de la hernia inguinal y las ventajas y los inconvenientes derivados de las diferentes técnicas anestésicas. En nuestro país no hay información acerca de la la técnica anestésica en la hernioplastia. Nuestro objetivo es realizar un estudio epidemiológico sobre las técnicas anestésicas en la cirugía de la hernia inguinal. Pacientes y métodos: Estudio epidemiológico transversal, descriptivo y multicéntrico en 20 hospitales de España. Cada centro incluyó a 12 pacientes sometidos a herniorrafia y registró datos sociodemográficos, antecedentes patológicos, técnica realizada, parámetros de recuperación y complicaciones. Resultados: Se incluyó a 238 pacientes (el 91% ASA I-II), con una media de edad de 57 (25-84) años, 213 varones y 25 mujeres. El régimen de hospitalización fue: cirugía ambulatoria un 47%, corta estancia un 26% y el resto con ingreso. Se realizó anestesia subaracnoidea en un 60%, anestesia general en un 27% y anestesia local con sedación, habitualmente benzodiacepinas, en un 13% de los casos. El alta de los pacientes intervenidos en régimen de cirugía ambulatoria fue entre 1 y 6 h en el 94 y el 100% de los casos de anestesia general y anestesia local respectivamente, frente a un 68% para la anestesia subaracnoidea. No hubo diferencias en las características del dolor, náuseas y vómitos entre las técnicas anestésicas; sin embargo, hubo 10 episodios de retención urinaria, todos ellos en el grupo de anestesia subaracnoidea, en pacientes varones y con una edad media de 68 años. Conclusiones: La anestesia subaracnoidea es la más utilizada en España para la herniorrafia, y se asocia con una elevada incidencia de retención urinaria y retraso en el alta hospitalaria (> 6 h en un 32% de los casos) en comparación con la anestesia local. Esta debería ser promovida activamente en nuestro país(AU)


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Assuntos
Humanos , Masculino , Feminino , Hérnia Inguinal/tratamento farmacológico , Hérnia Inguinal/cirurgia , Anestesia/métodos , Anestesia , Medicação Pré-Anestésica/tendências , Medicação Pré-Anestésica , Receptores de GABA-A/uso terapêutico , Anestesia Geral/métodos , Anestesia Geral , Anestesia Local , Estudos Epidemiológicos , Fatores Epidemiológicos , 28374
4.
Ann Chir ; 50(9): 747-54, 1996.
Artigo em Francês | MEDLINE | ID: mdl-9124781

RESUMO

The Shouldice operation remains the gold standard of inguinal hernia surgery. The authors describe the details of the surgical and anesthesiological technique of this intervention. The actual place of conventional open hernia surgery is discussed in the light of the rapidly developing laparoscopic approach.


Assuntos
Anestesia Local/métodos , Bupivacaína/uso terapêutico , Hérnia Inguinal/cirurgia , Lidocaína/uso terapêutico , Procaína/uso terapêutico , Anestésicos Locais/uso terapêutico , Quimioterapia Combinada , Hérnia Inguinal/tratamento farmacológico , Hérnia Inguinal/epidemiologia , Humanos , Incidência , Complicações Pós-Operatórias , Ensaios Clínicos Controlados Aleatórios como Assunto , Recidiva
5.
J Chir (Paris) ; 132(2): 61-6, 1995 Feb.
Artigo em Francês | MEDLINE | ID: mdl-7751342

RESUMO

Lichtenstein's technique for surgical cure of primary inguinal hernia using local anaesthesia is described. Since 1984, 3250 primary hernia operations were performed at the Lichtenstein Hernia Institute. There were 4 recurrences due to technical errors which are described. This tension-free technique is a reliable, simple and effective procedure. Patients return to normal activity within 2 to 14 days. Studies one 22300 operations performed by several surgeons produced similar results for post-operative recurrence and complications.


Assuntos
Anestesia Local/métodos , Bupivacaína/uso terapêutico , Hérnia Inguinal/cirurgia , Lidocaína/uso terapêutico , Bupivacaína/administração & dosagem , Quimioterapia Combinada , Seguimentos , Hérnia Inguinal/tratamento farmacológico , Humanos , Injeções Intradérmicas , Injeções Subcutâneas , Lidocaína/administração & dosagem , Masculino , Recidiva
6.
Presse Med ; 23(17): 801-4, 1994.
Artigo em Francês | MEDLINE | ID: mdl-8078838

RESUMO

Potentiated local anaesthesia has been generally used for repair of inguinal hernia since the Shouldice technique was first introduced in France in the early 80s. The technique requires a correct understanding of inguinal innervation and the properties of the local anaesthetic. The local anaesthetic is injected into the abdomino-genital and genito-crural nerves and at the line of incision allowing smooth surgical repair. Potentiation relieves patient apprehension. This method can be used for all types of inguinal hernia, whether simple or complicated and in all patients. There is no limitation for age or general condition. Contraindications are rare and include allergy or uncontrolled (no pacemaker) arrhythmias.


Assuntos
Anestesia Local/métodos , Hérnia Inguinal/tratamento farmacológico , Bupivacaína/efeitos adversos , Bupivacaína/uso terapêutico , Contraindicações , Hérnia Inguinal/fisiopatologia , Humanos , Lidocaína/efeitos adversos , Lidocaína/uso terapêutico , Doenças do Sistema Nervoso/induzido quimicamente
7.
Trop Doct ; 21(4): 176-8, 1991 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-1746042

RESUMO

This article documents the management of hernia operations in a Zambian General Hospital. Over a period of 28 months between 1979 and 1982, 146 patients were operated upon; 16 were managed under a general anaesthetic, eight with ketamine hydrochloride and 22 with spinal analgesia. The rest--100 patients--underwent repair with local analgesia. There were two surgical readmissions; the few who were readmitted for various other reasons have not been included. No recurrences were noted during the period of study. Morbidity was minimal and known surgical mortality was nil.


Assuntos
Anestesia Local/normas , Hérnia Inguinal/cirurgia , Tempo de Internação/estatística & dados numéricos , Adulto , Anestesia Local/métodos , Feminino , Seguimentos , Hérnia Inguinal/tratamento farmacológico , Hospitais Universitários , Humanos , Masculino , Complicações Pós-Operatórias/epidemiologia , Complicações Pós-Operatórias/etiologia , Zâmbia
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