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1.
J Spinal Cord Med ; 43(3): 306-314, 2020 05.
Artigo em Inglês | MEDLINE | ID: mdl-30475172

RESUMO

Objective: To determine the effect of a functional electrical stimulation (FES) rowing program on bone mineral density (BMD) when implemented within two years after SCI.Design: Prospective.Setting: Health Care Facility.Participants: Convenience sample; four adults with recent (<2 years) traumatic, motor complete SCI (C7-T12 AIS A-B).Intervention: A 90-session FES rowing exercise program; participants attended 30-minute FES training sessions approximately three times each week for the duration of their participation.Outcome Measures: BMD in the distal femur and tibia were measured using peripheral Quantitative Computed Tomography (pQCT) at enrollment (T0) and after 30 (T1), 60 (T2), and 90 (T3) sessions. Bone stimulus was calculated for each rower at each time point using the average number of weekly loading cycles, peak foot reaction force, and bone mineral content from the previous time point. A regression analysis was used to determine the relationship between calculated bone stimulus and change in femoral trabecular BMD between time points.Results: Trabecular BMD in the femur and tibia decreased for all participants in T0-1, but the rate of loss slowed or reversed between T1-2, with little-to-no bone loss for most participants during T2-3. The calculated bone stimulus was significantly correlated with change in femoral trabecular BMD (P = 0.016; R2 = 0.458).Conclusion: Consistent participation in an FES rowing program provides sufficient forces and loading cycles to reduce or reverse expected bone loss at the distal femur and tibia, at least temporarily, in some individuals within two years after SCI.Trial Registration: NCT02008149.


Assuntos
Densidade Óssea , Doenças Ósseas Metabólicas/prevenção & controle , Terapia por Estimulação Elétrica , Terapia por Exercício , Fêmur , Avaliação de Resultados em Cuidados de Saúde , Paraplegia/reabilitação , Traumatismos da Medula Espinal/reabilitação , Tíbia , Adulto , Doenças Ósseas Metabólicas/diagnóstico por imagem , Doenças Ósseas Metabólicas/etiologia , Terapia Combinada , Feminino , Fêmur/diagnóstico por imagem , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Paraplegia/complicações , Paraplegia/diagnóstico por imagem , Traumatismos da Medula Espinal/complicações , Traumatismos da Medula Espinal/diagnóstico por imagem , Tíbia/diagnóstico por imagem , Fatores de Tempo , Tomografia Computadorizada por Raios X , Esportes Aquáticos
2.
BMJ Support Palliat Care ; 10(4): e41, 2020 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-31201153

RESUMO

OBJECTIVES: The gait disturbance in spastic paraplegic patients lowers the gait speed, increases fall risk and eventually lower the quality of life. This study aims to investigate the effect of electrical twitch obtaining intramuscular stimulation (ETOIMS) on spastic paraplegic patients' gait speed and pattern. METHODS: A prospective short-term cohort study was designed in the outpatient clinic of the department of rehabilitation in a tertiary hospital. Patients with spastic paraplegia (N=5) were participated, including spinal cord tumour (N=2), cervical myelitis (N=1), hereditary spastic paraplegia (NIPA1 mutation; N=1) and spinal cord injury (N=1). The participants underwent ETOIMS. The target muscles were the bilateral quadratus lumborum, multifidus inserting to the L4 and L5 spinous process, and gluteus medius. Gait speed, gait pattern and subjective symptoms, including pain scores (measured by visual analogue scale), were compared before and immediately after the intervention. RESULTS: All patients subjectively reported reduced stiffness during walking and alleviated muscular pain in the lower back and gluteal area. After one session of ETOIMS, patient 1-4 showed 57%, 29%, 33% and 6 % improvement in gait speed, respectively, and all patients showed increased pelvic dissociation. CONCLUSIONS: The ETOIMS can be effective in improving gait speed and stability by relaxing the muscles or alleviating the pain in the lower back and gluteal area in spastic paraplegic patients.


Assuntos
Transtornos Neurológicos da Marcha/reabilitação , Paraplegia/reabilitação , Velocidade de Caminhada , Adulto , Idoso , Fenômenos Biomecânicos , Estudos de Coortes , Terapia por Estimulação Elétrica , Feminino , Transtornos Neurológicos da Marcha/etiologia , Humanos , Dor Lombar/terapia , Masculino , Pessoa de Meia-Idade , Músculo Esquelético/fisiopatologia , Paraplegia/complicações , Projetos Piloto , Estudos Prospectivos , Qualidade de Vida , Terapia de Relaxamento , Resultado do Tratamento
3.
Complement Ther Med ; 34: 170-185, 2017 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-28917371

RESUMO

OBJECTIVES: Spasticity remains highly prevalent in patients with spinal cord injury and multiple sclerosis. To summarize the effects of cannabinoids compared with usual care, placebo for spasticity due to multiple sclerosis (MS) or paraplegia. METHODS: Searches of MEDLINE, EMBASE, CENTRAL and LILACS to March 2017 were performed to identify randomized controlled trials. The primary outcomes were spasticity and spasm frequency. The criteria were any patient with MS and spasticity affecting upper or lower limbs or both, and that had a confirmed diagnosis of MS based on validated criteria, or however defined by the authors of the included studies. RESULTS: 16 trials including 2597 patients were eligible. Moderate-certainty evidence suggested a non-statistically significant decrease in spasticity (standardized mean difference (SMD) 0.36 [confidential interval (CI) 95% -0.17 to 0.88; p=0.18; I2=88%]), and spasm frequency (SMD 0.04 [CI 95% -0.15 to 0.22]). There was an increase in adverse events such as dizziness (risk ratio (RR) 3.45 [CI 95% 2.71-4.4; p=0.20; I2=23%]), somnolence (RR 2.9 [CI 95% 1.98-4.23; p=0.77; I2=0%]), and nausea (RR 2.25 [CI 95% 1.62-3.13; p=0.83; I2=0%]). CONCLUSIONS: There is moderate certainty evidence regarding the impact of cannabinoids in spasticity (average 0.36 more spasticity; 0.17 fewer to 0.88 more) due to multiple sclerosis or paraplegia, and in adverse events such as dizziness (419 more dizziness/1000 over 19 weeks), somnolence (127 more somnolence/1000 over 19 weeks), and nausea (125 more somnolence/1000 over 19 weeks).


Assuntos
Canabinoides/uso terapêutico , Esclerose Múltipla/complicações , Espasticidade Muscular/tratamento farmacológico , Paraplegia/complicações , Adulto , Canabinoides/efeitos adversos , Tontura , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Náusea , Traumatismos da Medula Espinal/complicações
4.
Clin Neurophysiol ; 127(9): 3118-3127, 2016 09.
Artigo em Inglês | MEDLINE | ID: mdl-27472548

RESUMO

OBJECTIVE: One of the brain signatures of the central neuropathic pain (CNP) is the theta band over-activity of wider cortical structures, during imagination of movement. The objective of the study was to investigate whether this over-activity is reversible following the neurofeedback treatment of CNP. METHODS: Five paraplegic patients with pain in their legs underwent from twenty to forty neurofeedback sessions that significantly reduced their pain. In order to assess their dynamic cortical activity they were asked to imagine movements of all limbs a week before the first and a week after the last neurofeedback session. Using time-frequency analysis we compared EEG activity during imagination of movement before and after the therapy and further compared it with EEG signals of ten paraplegic patients with no pain and a control group of ten able-bodied people. RESULTS: Neurofeedback treatment resulted in reduced CNP and a wide spread reduction of cortical activity during imagination of movement. The reduction was significant in the alpha and beta band but was largest in the theta band. As a result cortical activity became similar to the activity of other two groups with no pain. CONCLUSIONS: Reduction of CNP is accompanied by reduced cortical over-activity during movement imagination. SIGNIFICANCE: Understanding causes and consequences mechanism through which CNP affects cortical activity.


Assuntos
Imaginação/fisiologia , Movimento/fisiologia , Neuralgia/terapia , Neurorretroalimentação/métodos , Neurorretroalimentação/fisiologia , Paraplegia/terapia , Eletroencefalografia/métodos , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Neuralgia/etiologia , Neuralgia/psicologia , Paraplegia/complicações , Paraplegia/psicologia , Resultado do Tratamento
5.
BMC Neurol ; 15: 200, 2015 Oct 13.
Artigo em Inglês | MEDLINE | ID: mdl-26462651

RESUMO

BACKGROUND: Central neuropathic pain has a prevalence of 40% in patients with spinal cord injury. Electroencephalography (EEG) studies showed that this type of pain has identifiable signatures, that could potentially be targeted by a neuromodulation therapy. The aim of the study was to investigate the putative mechanism of neurofeedback training on central neuropathic pain and its underlying brain signatures in patients with chronic paraplegia. METHODS: Patients' EEG activity was modulated from the sensory-motor cortex, electrode location C3/Cz/C4/P4 in up to 40 training sessions Results. Six out of seven patients reported immediate reduction of pain during neurofeedback training. Best results were achieved with suppressing Ɵ and higher ß (20-30 Hz) power and reinforcing α power at C4. Four patients reported clinically significant long-term reduction of pain (>30%) which lasted at least a month beyond the therapy. EEG during neurofeedback revealed a wide spread modulation of power in all three frequency bands accompanied with changes in the coherence most notable in the beta band. The standardized low resolution electromagnetic tomography analysis of EEG before and after neurofeedback therapy showed the statistically significant reduction of power in beta frequency band in all tested patients. Areas with reduced power included the Dorsolateral Prefrontal Cortex, the Anterior Cingulate Cortex and the Insular Cortex. CONCLUSIONS: Neurofeedback training produces both immediate and longer term reduction of central neuropathic pain that is accompanied with a measurable short and long term modulation of cortical activity. Controlled trials are required to confirm the efficacy of this neurofeedback protocol on treatment of pain. The study is a registered UKCRN clinical trial Nr 9824.


Assuntos
Neuralgia/reabilitação , Neurorretroalimentação/métodos , Paraplegia/reabilitação , Adulto , Eletroencefalografia/métodos , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Neuralgia/etiologia , Paraplegia/complicações , Projetos Piloto , Resultado do Tratamento
6.
Heart Lung ; 42(4): 287-9, 2013.
Artigo em Inglês | MEDLINE | ID: mdl-23669409

RESUMO

A 56-year-old woman with a history of paraplegia and chronic pain due to neuromyelitis optica (Devic's syndrome) was admitted to a spinal cord injury unit for management of a sacral decubitus ulcer. During the hospitalization, she required emergency transfer to the intensive care unit (ICU) because of progressive deterioration of respiratory muscle function, severe respiratory acidosis, obtundation and hypotension. Upon transfer to the ICU, arterial blood gas revealed severe acute-on-chronic respiratory acidosis (pH 7.00, PCO2 120 mm Hg, PO2 211 mm Hg). The patient was immediately intubated and mechanically ventilated. Intravenous fluid boluses of normal saline (10.5 L in about 24 h) and vasopressors were started with rapid correction of hypotension. In addition, she was given hydrocortisone. Within 40 min of initiation of mechanical ventilation, there was improvement in acute respiratory acidosis. Sixteen hours later, however, the patient developed life-threatening hypokalemia (K(+) of 2.1 mEq/L) and hypomagnesemia (Mg of 1.4 mg/dL). Despite aggressive potassium supplementation, hypokalemia continued to worsen over the next several hours (K(+) of 1.7 mEq/L). Urine studies revealed renal potassium wasting. We reason that the recalcitrant life-threatening hypokalemia was caused by several mechanisms including total body potassium depletion (chronic respiratory acidosis), a shift of potassium from the extracellular to intracellular space (rapid correction of respiratory acidosis with mechanical ventilation), increased sodium delivery to the distal nephron (normal saline resuscitation), hyperaldosteronism (secondary to hypotension plus administration of hydrocortisone) and hypomagnesemia. We conclude that rapid correction of respiratory acidosis, especially in the setting of hypotension, can lead to life-threatening hypokalemia. Serum potassium levels must be monitored closely in these patients, as failure to do so can lead to potentially lethal consequences.


Assuntos
Acidose Respiratória/complicações , Hipopotassemia/etiologia , Respiração Artificial/efeitos adversos , Acidose Respiratória/terapia , Gasometria , Feminino , Humanos , Pessoa de Meia-Idade , Neuromielite Óptica/complicações , Paraplegia/complicações , Potássio/sangue
7.
Urologe A ; 51(12): 1692-6, 2012 Dec.
Artigo em Alemão | MEDLINE | ID: mdl-23160608

RESUMO

The established treatment of neurogenic lower urinary tract dysfunction (NLUTD) in patients with spinal cord injury (SCI) or meningomyelocele (MMC) is mainly conservative and is aimed at the lower urinary tract. For example, oral antimuscarinic medication is the standard treatment of neurogenic detrusor overactivity. Recently, however, treatment aiming directly or indirectly at the innervation of the urinary tract has gained increasing attention. Current evidence does not justify the use of nerve rerouting but the existing preliminary data are more promising for MMC patients than for those with SCI. Sacral neuromodulation is already a therapeutic option for incomplete SCI patients. Initial data from a pilot study indicate that in patients with complete SCI implementation in the spinal shock phase may prevent the development of NLUTD. Licensing of onabotulinum toxin A (Botox®) facilitated its clinical use for treating NLUTD but it is limited to the indication of neurogenic detrusor overactivity incontinence with a dosage of 200 IU. The mentioned unconventional treatments, although discussed controversially, are promising future treatment options for NLUTD.


Assuntos
Terapias Complementares/métodos , Terapias Complementares/tendências , Terapia por Estimulação Elétrica/métodos , Meningomielocele/terapia , Antagonistas Muscarínicos/uso terapêutico , Paraplegia/terapia , Bexiga Urinaria Neurogênica/terapia , Humanos , Meningomielocele/complicações , Paraplegia/complicações , Bexiga Urinaria Neurogênica/etiologia
8.
Spinal Cord ; 50(4): 309-14, 2012 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-22333891

RESUMO

STUDY DESIGN: Experimental trial based on the analytical study of radiographic standards of the sagittal spinal alignment in paraplegics in upright position under surface neuromuscular electrical stimulation (NMES). OBJECTIVES: To evaluate changes in radiographic standards of the sagittal spinal alignment of paraplegics under three different models of NMES used to optimize the global bipedal posture. SETTING: The University Hospital Ambulatory (UNICAMP), Campinas, SP, Brazil. METHODS: Ten paraplegic patients were selected. Each patient underwent three different models of NMES. The influence that each NMES model exerted over the sagittal balance of the spine was evaluated by lateral panoramic X-rays. Wilcoxon's test was used to compare the modifications observed in each NMES model in the group studied. RESULTS: Using the femoral quadriceps muscles' NMES as the starting point, the inclusion of the gluteus maximus' NMES generated an increase of the lumbar lordosis and a decrease of the spinal tilt angle. These alterations resulted in partial improvement of the anterior sagittal imbalance. NMES of the paralyzed paravertebral lumbar muscles resulted in a more expressive increase on the lumbar lordosis, with no significant change on the spinal tilt. On the latter model, however, an improvement of 20% was observed in the global sagittal imbalance due to a posterior translation of the spine as pointed out by the decrease in the C7-HA horizontal distance. CONCLUSIONS: The proposed NMES models were able to partially amend the anterior sagittal imbalance of the paraplegic patients in bipedal posture.


Assuntos
Terapia por Estimulação Elétrica/métodos , Pé/fisiopatologia , Paraplegia/complicações , Equilíbrio Postural/fisiologia , Radiografia/métodos , Curvaturas da Coluna Vertebral/reabilitação , Coluna Vertebral/diagnóstico por imagem , Adulto , Humanos , Masculino , Pessoa de Meia-Idade , Paraplegia/diagnóstico por imagem , Postura/fisiologia , Radiografia/normas , Curvaturas da Coluna Vertebral/etiologia , Curvaturas da Coluna Vertebral/fisiopatologia , Coluna Vertebral/fisiopatologia , Adulto Jovem
9.
Clin Ter ; 162(1): e1-5, 2011.
Artigo em Inglês | MEDLINE | ID: mdl-21448535

RESUMO

INTRODUCTION: Fournier's gangrene (FG) is a rapidly developing necrotizing fasciitis that originates in genital and perineal region. The mortality rate is high and requires prompt diagnosis, antibiotic treatment and extensive necrosectomy with derivative colostomy. Vacuum Assisted Closure (VAC) is a wound care system of paramount importance in the treatment of complex wounds, including the perineum. MATERIALS AND METHODS: We evaluated 6 cases of FG (males, mean age: 54.6 yrs) of the last 3 years (February 2008-August 2010). All patients were diabetics. We used intravenous antibiotic treatment and early surgical debridement with colostomy, followed by immediate positioning of a VAC device (NP 125-200 mmHg). The dressing changes were done every 3-4 days. Hyperbaric oxygen therapy (HBOT) was given only to one patient. Microbiological etiology was assessed by multiple cultures to tailor the antimicrobial treatment. RESULTS: The VAC therapy reduces the number of dressings and the hospital length of stay (LOS), in agreement with the literature; in one of the cases a secondary reconstructive surgical intervention was possible. The colostomy was reversed in all patients within 3 months. CONCLUSIONS: Negative pressure is a time saving device, reducing days of hospitalization, patient's discomfort and number of medications. The possibility of a early reconstructive surgery improves significantly quality of life.


Assuntos
Gangrena de Fournier/cirurgia , Tratamento de Ferimentos com Pressão Negativa , Adulto , Idoso , Antibacterianos/uso terapêutico , Colostomia , Terapia Combinada , Desbridamento , Complicações do Diabetes/cirurgia , Gangrena de Fournier/diagnóstico por imagem , Gangrena de Fournier/tratamento farmacológico , Gangrena de Fournier/terapia , Humanos , Oxigenoterapia Hiperbárica , Hipertensão/complicações , Masculino , Pessoa de Meia-Idade , Obesidade/complicações , Paraplegia/complicações , Estudos Retrospectivos , Tomografia Computadorizada por Raios X , Resultado do Tratamento
10.
Am J Chin Med ; 38(6): 1015-25, 2010.
Artigo em Inglês | MEDLINE | ID: mdl-21061457

RESUMO

The clinical efficacy of electroacupuncture and acupuncture in combination with medication for the treatment of thoracolumbar intervertebral disc herniation was investigated in paraplegic dogs with intact deep pain perception. To evaluate the additional effect of electroacupuncture, dogs treated with conventional medicines alone were compared to dogs treated with electroacupuncture and acupuncture and conventional medicine. Medical records of 80 dogs were reviewed for this investigation and classified into two groups undergoing different treatment methods: (1) treatment with conventional medicine alone (Group C, n = 37) and (2) treatment with conventional medicine combined with electroacupuncture and acupuncture (Group CE, n = 43). Prednisone was the conventional medicine and electroacupuncture was applied at GV07 and GV02-1 at 0.5-2.5 mV, mixed Hz of 2 and 15 Hz for 25-30 min. Acupuncture was performed locally at urinary bladder meridian points near the lesion, and bilaterally distantly at GB30, GB34, and ST36. Treatment efficacy was evaluated by post-operative neurologic function, ambulation, relapse, complication, and urinary function. Ambulation recovery was more prevalent in Group CE than Group C (p = 0.01) and recovery of ambulation and back pain relief time was shorter in Group CE compared to Group C (p = 0.011 and 0.001, respectively). Relapse rate was significantly lower in Group CE (p = 0.031). The results suggest that a combination of electroacupuncture and acupuncture with conventional medicine is more effective than conventional medicine alone in recovering ambulation, relieving back pain, and decreasing relapse. Electroacupuncture and acupuncture is thus a reasonable option for the treatment of intervertebral disc herniation in paraplegic dogs with intact deep pain perception.


Assuntos
Dor nas Costas/veterinária , Eletroacupuntura/veterinária , Glucocorticoides/uso terapêutico , Deslocamento do Disco Intervertebral/veterinária , Paraplegia/veterinária , Prednisona/uso terapêutico , Caminhada/fisiologia , Pontos de Acupuntura , Animais , Dor nas Costas/tratamento farmacológico , Dor nas Costas/terapia , Cães , Eletroacupuntura/métodos , Glucocorticoides/farmacologia , Deslocamento do Disco Intervertebral/complicações , Deslocamento do Disco Intervertebral/terapia , Vértebras Lombares , Meridianos , Medição da Dor/veterinária , Paraplegia/complicações , Prednisona/farmacologia , Recidiva , Vértebras Torácicas , Resultado do Tratamento
11.
J Wound Care ; 19(9): 408-12, 2010 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-20852570

RESUMO

This paper highlights the important nexus between physical and mental health by examining a case concerning a patient with a lower spinal cord injury and mental illness who subsequently developed two pressure ulcers. It examines how clinicians can benefit from looking beyond typical assumptions when caring for an individual with complex needs in the community setting. In such circumstances, the need for a holistic and collaborative approach to wound care is vital. This involves taking into account the individual's mental health care needs, which can be overlooked in the first instance. Recommendations for clinical practice centre on involving the patient in his or her dietary, psychological and physical care, thereby helping to build resilience to any mental health problems and promoting a positive physical recovery.


Assuntos
Transtorno Depressivo/complicações , Paraplegia/complicações , Úlcera por Pressão/terapia , Traumatismos da Medula Espinal/complicações , Enfermagem em Saúde Comunitária , Desbridamento , Transtorno Depressivo/diagnóstico , Transtorno Depressivo/prevenção & controle , Necessidades e Demandas de Serviços de Saúde , Saúde Holística , Humanos , Masculino , Pessoa de Meia-Idade , Avaliação em Enfermagem , Paraplegia/reabilitação , Educação de Pacientes como Assunto , Úlcera por Pressão/etiologia , Fatores de Risco , Higiene da Pele , Traumatismos da Medula Espinal/reabilitação
12.
Neurourol Urodyn ; 29(8): 1433-8, 2010 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-20589714

RESUMO

AIMS: To present new strategies of pelvic nerves stimulation to enhance micturition, to control spasticity, and to recover locomotion in paraplegics. METHODS: Three consecutive patients-Th5, Th7, and Th10 spinal cord injured-underwent laparoscopic transperitoneal implantation of octipolar electrodes to the sciatic and the pudendal nerves and one double extradural Brindley-Finetech electrode bilaterally to the sacral nerve roots S3 and S4. The two octipolar electrodes were connected to an implanted rechargeable generator, while the double Brindley electrode was connected to an implanted Brindley-Finetech receiver block. RESULTS: Continuous stimulation of the sciatic and pudendal nerves at a frequency of 20 Hz in all three patients permits complete control of the spasticity of the lower extremities and of reflex incontinence. Bladder emptying is obtained by sacral nerve roots stimulation alone in the first patient, by simple interruption of pudendal stimulation in the second ("pudendal-deblockade") and by simultaneous sacral nerve roots stimulation with high-frequency pudendal nerve blockade in the third patient. Functional electrical stimulation of the femoral nerves enables the Th4 paraplegics lower-limb cycling and the two further patients standing and alternative locomotion. CONCLUSION: This short series indicated that laparoscopic implantation of neuroprothesis to the pelvic nerves offers absolutely new strategies based on new combinations of various reported methods to enhance bladder functions and to recover some locomotion in paraplegics.


Assuntos
Terapia por Estimulação Elétrica , Locomoção , Extremidade Inferior/inervação , Paraplegia/terapia , Bexiga Urinária Hiperativa/terapia , Bexiga Urinária/inervação , Incontinência Urinária/terapia , Micção , Terapia por Estimulação Elétrica/instrumentação , Eletrodos Implantados , Feminino , Nervo Femoral/fisiopatologia , Humanos , Laparoscopia , Masculino , Paraplegia/complicações , Paraplegia/fisiopatologia , Ereção Peniana , Nervo Isquiático/fisiopatologia , Resultado do Tratamento , Bexiga Urinária Hiperativa/etiologia , Bexiga Urinária Hiperativa/fisiopatologia , Incontinência Urinária/etiologia , Incontinência Urinária/fisiopatologia
13.
Arch Phys Med Rehabil ; 91(5): 669-78, 2010 May.
Artigo em Inglês | MEDLINE | ID: mdl-20434602

RESUMO

OBJECTIVE: To investigate whether electric stimulation therapy (EST) administered as part of a community-based, interdisciplinary wound care program accelerates healing of pressure ulcers in people with spinal cord injury (SCI). DESIGN: Single-blind, parallel-group, randomized, controlled, clinical trial. SETTING: Community-based home care setting, Ontario, Canada. PARTICIPANTS: Adults (N=34; mean age +/- SD, 51+/-14y) with SCI and stage II to IV pressure ulcers. INTERVENTIONS: Subjects were stratified based on wound severity and duration and randomly assigned to receive either a customized, community-based standard wound care (SWC) program that included pressure management or the wound care program plus high-voltage pulsed current applied to the wound bed (EST+SWC). MAIN OUTCOME MEASURES: Wound healing measured by reduction in wound size and improvement in wound appearance at 3 months of treatment with EST+SWC or SWC. RESULTS: The percentage decrease in wound surface area (WSA) at the end of the intervention period was significantly greater in the EST+SWC group (mean +/- SD, 70+/-25%) than in the SWC group (36+/-61%; P=.048). The proportion of stage III, IV, or X pressure ulcers improving by at least 50% WSA was significantly greater in the EST+SWC group than in the SWC group (P=.02). Wound appearance assessed using the photographic wound assessment tool was improved in wounds treated with EST+SWC but not SWC alone. CONCLUSIONS: These results demonstrate that EST can stimulate healing of pressure ulcers of people with SCI. EST can be incorporated successfully into an interdisciplinary wound care program in the community.


Assuntos
Terapia por Estimulação Elétrica , Úlcera por Pressão/terapia , Traumatismos da Medula Espinal/complicações , Adulto , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Paraplegia/complicações , Úlcera por Pressão/etiologia , Características de Residência , Método Simples-Cego , Cicatrização
14.
J Med Eng Technol ; 34(3): 224-31, 2010 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-20170355

RESUMO

The aim of this paper is to show the feasibility of the use of functional electrical stimulation (FES) applied to the lower back muscles for pressure sores prevention in paraplegia. The hypothesis under study is that FES induces a change in the pressure distribution on the contact area during sitting. Tests were conducted on a paraplegic subject (T5), sitting on a standard wheelchair and cushion. Trunk extensors (mainly the erector spinae) were stimulated using surface electrodes placed on the skin. A pressure mapping system was used to measure the pressure on the sitting surface in four situations: (a) no stimulation; (b) stimulation on one side of the spine only; (c) stimulation on both sides, at different levels; and (d) stimulation at the same level on both sides, during pressure-relief manoeuvres. A session of prolonged stimulation was also conducted. The experimental results show that the stimulation of the erector spinae on one side of the spine can induce a trunk rotation on the sagittal plane, which causes a change in the pressure distribution. A decrease of pressure on the side opposite to the stimulation was recorded. The phenomenon is intensified when different levels of stimulation are applied to the two sides, and such change can be sustained for a considerable time (around 5 minutes). The stimulation did not induce changes during pressure-relief manoeuvres. Finally, from this research we can conclude that the stimulation of the trunk extensors can be a useful tool for pressure sores prevention, and can potentially be used in a routine for pressure sores prevention based on periodical weight shifts.


Assuntos
Terapia por Estimulação Elétrica/métodos , Músculo Esquelético/fisiopatologia , Paraplegia/fisiopatologia , Paraplegia/terapia , Úlcera por Pressão/prevenção & controle , Úlcera por Pressão/fisiopatologia , Dorso , Humanos , Músculo Esquelético/inervação , Paraplegia/complicações , Úlcera por Pressão/etiologia , Resultado do Tratamento
15.
J Minim Invasive Gynecol ; 16(1): 98-101, 2009.
Artigo em Inglês | MEDLINE | ID: mdl-19110191

RESUMO

STUDY OBJECTIVE: To report on our technique of sacral laparoscopic implantation of aneuroprosthesis-LION procedure-for recovery of bladder/intestinal/sexual function in paralyzed patients after spinal cord injury. DESIGN: Prospective case series report. SETTING: Academic community teaching hospital. PATIENTS: Eight consecutive complete T-paralyzed patients after explantation of a previous dorsal implanted Brindley-Finetech controller with a sacral deafferentation. INTERVENTIONS: Laparoscopic transperitoneal exposure of the sacral plexuse and bilateral implantation of Brindley-Finetech electrodes to the sacral nerve roots S2 to S4. MEASUREMENTS AND MAIN RESULTS: Feasibility, complications, and outcome of the procedures. In 6 patients, recovery of electrically induced micturition and defecation could be obtained and in 2 men recovery of electrically induced erection. In 2 other patients, exposure and intraoperative stimulation of the sacral nerve roots showed irreversible destruction of the motoric vesical and rectal nerves. In one, the bilateral implantation of neuromodulation electrodes permitted complete control of the spasticity of the lower limbs and to the autonomic dysreflexia. CONCLUSION: The laparoscopic transperitoneal approach offers minimally invasive access for implantation of electrodes to the sacral nerve roots in paralyzed patients for recovery of pelvic visceral functions after failure of a previous implanted dorsal Brindley-Finetech controller with sacral deafferentation.


Assuntos
Terapia por Estimulação Elétrica/métodos , Laparoscopia/métodos , Paraplegia , Traumatismos da Medula Espinal/complicações , Bexiga Urinaria Neurogênica , Adulto , Estudos de Coortes , Eletrodos Implantados , Incontinência Fecal/etiologia , Incontinência Fecal/cirurgia , Feminino , Humanos , Plexo Lombossacral/fisiopatologia , Pessoa de Meia-Idade , Paraplegia/complicações , Paraplegia/etiologia , Paraplegia/terapia , Disfunções Sexuais Fisiológicas/etiologia , Disfunções Sexuais Fisiológicas/cirurgia , Bexiga Urinaria Neurogênica/etiologia , Bexiga Urinaria Neurogênica/cirurgia
16.
Int Wound J ; 5 Suppl 2: 27-9, 2008 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-18577136

RESUMO

The authors present a patients story to demonstrate the usefulness of a complete patient approach, incorporating V.A.C. therapy, to achieving clinical success from the patients perspective. The article discusses why a total patient approach is important and therapeutic flexibility increases the chance of a successful outcome for all involved.


Assuntos
Saúde Holística , Tratamento de Ferimentos com Pressão Negativa , Úlcera por Pressão/terapia , Adulto , Causalidade , Exsudatos e Transudatos , Hóquei , Humanos , Masculino , Tratamento de Ferimentos com Pressão Negativa/métodos , Tratamento de Ferimentos com Pressão Negativa/psicologia , Avaliação em Enfermagem , Paraplegia/complicações , Úlcera por Pressão/etiologia , Úlcera por Pressão/psicologia , Autocuidado , Higiene da Pele/métodos , Higiene da Pele/enfermagem , Cicatrização
17.
Spinal Cord ; 46(1): 70-3, 2008 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-17420771

RESUMO

BACKGROUND: A number of techniques are being investigated to accomplish bladder control recovery in paralyzed patients using the neurostimulation, but currently, all techniques are based on the dorsal implantation of the electrodes using a laminectomy. METHODS: On 27 April 2006 we performed a laparoscopic implantation of a Finetech-Brindley bladder controller on the endopelvic sacral roots in a Th8 completely paralyzed woman who had previously undergone the removal of a Brindley controller due to an arachnoiditis after extrathecal implantation with intradural sacral deafferentation. RESULTS: We required about 3.5 h for the entire surgical procedure; no complications occurred and the patients went home on 5th postoperative day. The patient is now able to void empty her bladder and her rectum using the controller without further need for self-catheterisation. CONCLUSIONS: The presented new technique of laparoscopic implantation of electrodes on the endopelvic portion of the sacral nerve roots is an option to be considered in all paralyzed patients with further wish for electrical induced miction/defecation after previous deafferentation.


Assuntos
Terapia por Estimulação Elétrica/métodos , Laparoscopia/métodos , Paraplegia/complicações , Traumatismos da Medula Espinal/complicações , Raízes Nervosas Espinhais/cirurgia , Bexiga Urinaria Neurogênica/terapia , Defecação , Eletrodos Implantados , Feminino , Humanos , Pessoa de Meia-Idade , Procedimentos Neurocirúrgicos/instrumentação , Procedimentos Neurocirúrgicos/métodos , Paraplegia/fisiopatologia , Satisfação do Paciente , Pelve/anatomia & histologia , Pelve/cirurgia , Espaço Retroperitoneal/anatomia & histologia , Espaço Retroperitoneal/cirurgia , Sacro/anatomia & histologia , Sacro/cirurgia , Traumatismos da Medula Espinal/fisiopatologia , Raízes Nervosas Espinhais/fisiopatologia , Resultado do Tratamento , Bexiga Urinária/inervação , Bexiga Urinária/fisiopatologia , Bexiga Urinária/cirurgia , Bexiga Urinaria Neurogênica/etiologia , Bexiga Urinaria Neurogênica/fisiopatologia , Micção
18.
Acta Neurochir Suppl ; 97(Pt 1): 333-9, 2007.
Artigo em Inglês | MEDLINE | ID: mdl-17691394

RESUMO

Spinal cord injured patients with a suprasacral lesion usually develop a spastic bladder. The neurogenic detrusor overactivity (NDO) and the overactive external sphincter cause incontinence and threaten these patients with recurrent urinary tract infections (UTI), renal failure and autonomic dysreflexia. All of these severe disturbances may be well managed by sacral deafferentation (SDAF) and implantation of a sacral anterior root stimulator (SARS). Since September 1986 to December 2002, 464 paraplegic patients (220 females, 244 males) received a SDAF-SARS. The SDAF was done intradurally in almost all cases, which means that we used a single operation field to do a two-stages procedure (SDAF and SARS). The results include data on 440 patients with a mean follow-up of 8.6 years (18 months to 18 years) until December 2004. The complete deafferentation was successful in 95.2%. Of these patients, 420 paraplegics use the SARS for voiding, (frequency 4.7 per day) and 401 for defecation (frequency 4.7 per week). Continence was achieved in 364 patients (83%). UTIs decreased from 6.3 per year preoperatively to 1.2 per year postoperatively. Kidney function remained stable. Early complications were 6 CSF leaks and 5 implant infections. Late compli cations included receiver or cable failures and required surgical repair in 44 patients. A step-by-step program for trouble-shooting distinguishes implant failure from myogenic or neurogenic failure. SDAF is able to restore the reservoir function of urinary bladder and makes the patient achieve continence. Autonomic dysreflexia disappeared in most cases. By accurate adjustment of stimulation parameters, it is possible for the patient to have a low resistance micturition. The microsurgical technique requires intensive education. In addition, the therapist should be able to manage late complications.


Assuntos
Vias Aferentes/cirurgia , Terapia por Estimulação Elétrica/métodos , Raízes Nervosas Espinhais/cirurgia , Bexiga Urinaria Neurogênica/cirurgia , Bexiga Urinária/inervação , Adolescente , Adulto , Idoso , Terapia por Estimulação Elétrica/história , Terapia por Estimulação Elétrica/instrumentação , Eletrodos Implantados/história , Feminino , Seguimentos , História do Século XX , História do Século XXI , Humanos , Masculino , Pessoa de Meia-Idade , Paraplegia/complicações , Complicações Pós-Operatórias , Estudos Retrospectivos , Raízes Nervosas Espinhais/fisiopatologia , Bexiga Urinaria Neurogênica/etiologia
19.
Pain ; 130(3): 294-298, 2007 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-17335974

RESUMO

Neuropathic pain after spinal cord injury is not well understood and is difficult to treat. One possible cause is mismatch between motor commands and sensory feedback. This two-part study in five paraplegic patients investigated whether a visual illusion aimed to correct this mismatch reduces pain. In study 1, patients undertook three conditions: (i) virtual walking: with a mirror placed in front of a screen, patients aligned their own upper body with a film of a lower body walking. Patients imagined walking and 'watched themselves' walk; (ii) guided imagery; (iii) watching a film. One patient withdrew from virtual walking because of distress. For all patients, the mean (95% CI) decrease in pain (100 mm VAS) was 42 mm (approximately 65%) (11-73 mm) for virtual walking, 18 mm (4-31 mm) for guided imagery and 4mm (-3 to 11 mm) for watching the film. Mean (95% CI) time to return to pre-task pain was 34.9 min (20.1-49.8 min) for virtual walking; 13.9 min (-0.9 to 28.8 min) for the guided imagery and 16.3 min (1.5-31.2 min) for the film. To investigate its clinical utility, four patients underwent virtual walking every weekday for 3 weeks. Mean (95% CI) decrease in pain was 53 mm (45-61 mm) at post training and 43 mm (27-58 mm) at 3-month follow-up. Virtual walking may be a viable treatment for pain after spinal cord injury. A clinical trial seems warranted.


Assuntos
Ilusões , Neuralgia/terapia , Paraplegia/complicações , Modalidades de Fisioterapia , Traumatismos da Medula Espinal/complicações , Adulto , Vias Aferentes/fisiologia , Vias Eferentes/fisiologia , Humanos , Imagens, Psicoterapia , Imaginação , Pessoa de Meia-Idade , Neuralgia/etiologia , Neuralgia/reabilitação , Paraplegia/reabilitação , Estimulação Luminosa , Desempenho Psicomotor , Traumatismos da Medula Espinal/reabilitação , Resultado do Tratamento , Interface Usuário-Computador , Caminhada
20.
Pflege Z ; 59(3): 2-8, 2006 Mar.
Artigo em Alemão | MEDLINE | ID: mdl-16572678

RESUMO

UNLABELLED: Patients with paraplegia caused by spinal cord injuries have to deal with the loss of the central nervous regulation of the bowel functions. The management of defaecation can take a lot of their daily time. To support the colon motility, different methods of abdominal massage are used in nursing practice. But a review of current international literature reveals, that there is still a lack of evidence for the effect of abdominal massage on defaecation. In order to prove this effect, a pilot study was conducted using a quasi-experimental design with time series and including seven patients with paraplegia caused by spinal cord injury. Data were collected over three weeks: one week before intervention, during the intervention week and one week after intervention. In the intervention week, the patients received a specific abdominal massage each morning before breakfast. Following outcome-criteria have been considered: frequency and duration of defaecation, amount and consistency of faeces as well as subjective perception of the massage and its effects. RESULTS: Some distinctive changes in the frequency and duration of defaecation could be registered over time. Most patients regarded the massage as a comfortable intervention that may have positive effects of the defaecation. Due to the pilot character of the study further research is necessary in order to validate these effects.


Assuntos
Abdome , Constipação Intestinal/enfermagem , Massagem/enfermagem , Paraplegia/enfermagem , Traumatismos da Medula Espinal/enfermagem , Pesquisa em Enfermagem Clínica , Constipação Intestinal/etiologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Paraplegia/complicações , Projetos Piloto , Traumatismos da Medula Espinal/complicações , Resultado do Tratamento
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