Efficacy of electro-acupuncture versus sham acupuncture for diabetic peripheral neuropathy: study protocol for a three-armed randomised controlled trial.

INTRODUCTION: Specific treatment for diabetic peripheral neuropathy (DPN) is still lacking, and acupuncture may relieve the symptoms. We intend to investigate the efficacy and safety of electro-acupuncture (EA) in alleviating symptoms associated with DPN in diabetes. METHODS AND ANALYSIS: This multicentre, three-armed, participant- and assessor-blind, randomised, sham-controlled trial will recruit 240 eligible participants from four hospitals in China and will randomly assign (1:1:1) them to EA, sham acupuncture (SA) or usual care (UC) group. Participants in the EA and SA groups willl receive either 24-session EA or SA treatment over 8 weeks, followed by an 8-week follow-up period, while participants in the UC group will be followed up for 16 weeks. The primary outcome of this trial is the change in DPN symptoms from baseline to week 8, as rated by using the Total Symptom Score. The scale assesses four symptoms: pain, burning, paraesthesia and numbness, by evaluating the frequency and severity of each. All results will be analysed with the intention-to-treat population. ETHICS AND DISSEMINATION: The protocol has been approved by the Ethics Committee of the Beijing University of Chinese Medicine (Identifier: 2022BZYLL0509). Every participant will be informed of detailed information about the study before signing informed consent. The results of this trial will be published in a peer-reviewed journal. TRIAL REGISTRATION NUMBER: ChiCTR2200061408.

Polyglycerol polyricinoleate and lecithin stabilized water in oil nanoemulsions for sugaring Beijing roast duck: Preparation, stability mechanisms and color improvement.

Traditional Beijing roast duck often suffers from uneven color and high sugar content after roasting. Water-in-oil (W/O) nanoemulsion is a promising alternative to replace high concentration of sugar solution used in sugaring process according to similarity-intermiscibility theory. Herein, 3% of xylose was embedded in the aqueous phase of W/O emulsion to replace 15% maltose solution. W/O emulsions with different ratios of lecithin (LEC) and polyglycerol polyricinoleate (PGPR) were constructed by high-speed homogenization and high-pressure homogenization. Distribution and penetration extent of solutions and emulsions through the duck skin, as well as the color uniformity of Beijing roast duck were analyzed. Emulsions with LEC:PGPR ratios of 1:3 and 2:2 had better stability. Stable interfacial film and spatial structure were important factors influencing emulsion stabilization. The stable W/O emulsions could more uniformly distribute onto the surface of duck skin and longitudinally penetrate through the skin than solutions.

Do all algae grow faster in environments replenished by reclaimed water? Examples of two effluents produced in Beijing.

Reclaimed water with nitrogen, phosphorus, and other contaminants may trigger algal blooms during its ecological utilization in replenishing rivers or lakes. However, the effect of reclaimed water on algal growth rates is not well understood. In this study, the growth potentials of algae in terms of Cyanophyta, Chlorophyta, and Bacillariophyta, as well as mixed algae in both regular culture medium and reclaimed water produced from treatment plants in Beijing with similar N and P concentrations, were compared to evaluate whether reclaimed water could facilitate algal growth. In addition, reclaimed water was also sterilized to verify the impact of bacteria's presence on algal growth. The results indicated that most algae grew faster in reclaimed water, among which the growth rate of Microcystis aeruginosa even increased by 5.5 fold. The growth of mixed algae in reclaimed water was not enhanced due to the strong adaptive ability of the community structure. Residual bacteria in the reclaimed water were found to be important contributors to algal growth. This work provided theoretical support for the safe and efficient utilization of reclaimed water.

Effects of airborne pollen on allergic rhinitis and asthma across different age groups in Beijing, China.

In the context of global warming and rapid urbanization, pollen has become a significant public health concern for Chinese citizens. However, there is a paucity of epidemiological research on the impact of pollen on allergen-linked diseases, such as allergic rhinitis and asthma, in China. Using data from the Beijing Chaoyang Hospital between 2013 and 2019, which included allergic rhinitis and asthma incidence, meteorological records, and air pollution data, we employed a Generalized Additive Model (GAM) to examine the relationship between overall and type-specific pollen concentrations in relation to varying population exposures. We found that increased overall pollen concentrations significantly increased the risks of allergic rhinitis and asthma in diverse populations. Notably, the risk of allergic rhinitis was higher than that of asthma at equivalent pollen concentrations. Seasonal trends indicated that spring pollen peaks, primarily from trees, were associated with a lower risk of both allergic rhinitis and asthma than autumn peaks, predominantly from weeds. This study underscores the importance of identifying pollen species that pose heightened risks to different demographic groups across seasons, thereby providing targeted interventions for public health agencies.

Exploring global research status and trends in anti-obesity effects of traditional Chinese medicine through intestinal microbiota: a bibliometric study.

Background: The intestinal microbiota (IM) has been found to contribute to metabolic disorders that lead to excessive fat accumulation, systemic and chronic low-grade inflammation, and insulin resistance in the host. Current research highlights a pivotal interaction between IM and traditional Chinese medicine (TCM) in mitigating obesity-related diseases. Undeniably, IM stands as a central focus in TCM research aimed at preventing and treating obesity. Therefore, tracing the progress and trends in this field can offer valuable references and insights for future studies. Methods: On June 17, 2023, we conducted a literature search on the topic of "IM and obesity in TCM" spanning the period from 2009 to 2023. We extracted the primary information of the publications, which includes complete records and reference citations, from the Science Citation Index Expanded (SCI-E) within the Web of Science Core Collection (WoSCC). To visualize and analyze the literature, we utilized CiteSpace and VOSviewer for bibliometric analysis. Results: During the past fifteen years, a rapid increase in the number of publications has been observed. The cooperative networks demonstrate China, Beijing University of Chinese Medicine, and Food & Function as the most active countries, organizations, and journals in this field, respectively. Liu Bin has contributed the most publications. A paper by Xu Jia, published in 2014, holds the highest Local Citation Score (LCS). Analyses of keyword co-occurrence and reference co-citation indicate that the research hotspots of IM and obesity in TCM are primarily focused on the metabolic benefits driven by endogenous functional metabolic molecules generated by TCM regulation of IM. Other focal points include the mechanism by which TCM regulates IM to restore the intestinal mucosal barrier This is a provisional file, not the final typeset article, and manages the gut-organ axis, the metabolic advantages of acupuncture's regulation of IM, and the process by which Chinese medicine small molecules transform IM. Conclusion: This research offers a comprehensive understanding of the current status, hotspots, and trends in global TCM research. Additionally, it provides a comprehensive summary and exploration of the latest advancements in this field, thereby emphasizing the essence of TCM more effectively.

[Medical figures in Wang Ao Ji].

Wang Ao was a famous politician and litterateur in the middle of Ming Dynasty. Wang Ao Ji comprehensively sorts out Wang's works for the first time, and collects all the poems and notes written by himself. A total of 38 physicians were recorded in Wang Ao Ji, among them, Wang Ao had close contacts with many physicians such as Zhou Geng, Zhou Xu'an, Sheng Rubi, Zhang Yangzheng and Chen Chong. Wang Ao and Zhou Geng are both core members of the literary society of Wuzhong, in the capital of Beijing. Wang Ao once wrote an epitaph for Zhou Xu'an, a tablet inscription for Sheng Rubi and a biography for Zhang Yangzheng. And Chen Chong once cured Wang's nephew's diarrhea caused by acne rash.The biographical records of physicians in Wang Ao Ji are highly reliable, and some medical information is the main source of official history and medical history works, which contains important historical value. Relevant contents about medical figures recorded in class of works, local chronicles, genealogy, anthology, notes and other ancient books, to a great extent, enrich biographical data of physicians, which is worth further research.

[The General medical journal of China].

The "General medical journal of China", started by Hou Yuwen in Beijing in 1923, was renamed the "Journal of Oriental Medicine" in 1933. This journal influenced the medical field in terms of improving medical development, and in particular, playing an important role in spreading western medicine in China in the 1920s and 1930s. The journal was operated and issued in Beijing, Shenyang, and Changchun successively, recording important medical activities and medical experiences at that time, presenting the historical events of multi-dimensional interaction and exchange between medicine and society, medicine and culture, and medicine and politics. In this sense, it has an important historical value.

Sensitization characteristics in allergic rhinitis and transport pathway for Artemisia pollen in northern Beijing, China.

The genus Artemisia, an important allergen related to Allergic Rhinitis (AR), is widespread in temperate regions. However, the sensitization rate of Artemisia pollen varies significantly, and the source of Artemisia pollen is not clear. Based on continuous daily airborne pollen monitoring in the summer and autumn of 2019 and 2020 in northern Beijing, the daily number of AR patient visits during the same period, and the detection of allergen serum-specific immunoglobulin E (sIgE) in some AR patients, this study discusses the sensitization rate of Artemisia pollen and its transmission pathway and possible source area. The results show that (1) Artemisia pollen is the most important airborne pollen in summer and autumn in northern Beijing, and the pollen concentration is significantly related to the daily number of AR patient visits; (2) the rate of AR patients testing positive for Artemisia pollen allergens is 32.35 %, which is the first risk allergen and is consistent with the high sensitization rate of Artemisia pollen in northern China; and (3) in addition to local sources, central and southern Inner Mongolia, southern Mongolia and northwestern China are potential source areas of Artemisia pollen within the study area. This study provides first-hand data for accurately understanding the allergenic characteristics and sources of Artemisia pollen in northern Beijing and provides a scientific basis for the prevention of AR induced by Artemisia pollen in patients in China.

Effects of pollen concentration on allergic rhinitis in children: A retrospective study from Beijing, a Chinese megacity.

With global climate change and rapid urbanization, the prevalence of allergic diseases caused by pollen is rising dramatically worldwide with unprecedented complexity and severity, especially for children in mega-cities. However, because of the lack of long time-series pollen concentrations data, the accurate evaluation of the impact of pollen on allergic rhinitis (AR) was scarce in the Chinese metropolis. A generalized additive model was used to assess the effect of pollen concentration on pediatric AR outpatient visits in Beijing from 2014 to 2019. A stratified analysis of 10 pollen species and age-gender-specific groups was also conducted during the spring and summer-autumn peak pollen periods separately. Positive associations between pollen concentration and pediatric AR varied with the season and pollen species were detected. Although the average daily pollen concentration is higher during the spring tree pollen peak, the influence was stronger at the summer-autumn weed pollen peak with the maximum relative risk 1.010 (95% CI 1.009, 1.011), which was higher than the greatest relative risk, 1.003 (95% CI 1.002, 1.004) in the spring peak. The significant adverse effects can be sustained to lag10 during the study period, and longer in the summer-autumn peak (lag13) than in the spring peak (lag8). There are thresholds for the health effects and they varied between seasons. The significant effect appeared when the pollen concentration was higher than 3.74 × 105 grain·m-2·d-1 during the spring tree pollen peaks and 4.70 × 104 grain·m-2·d-1 during the summer-autumn weed pollen peaks. The stratified results suggested that the species-specific effects were heterogeneous. It further highlights that enough attention should be paid to the problem of pollen allergy in children, especially school-aged children aged 7-18 years and weed pollen in the summer-autumn peak pollen period. These findings provide a more accurate reference for the rational coordination of medical resources and improvement of public health.

[Accumulation, Migration, and Transformation of Soil Phosphorus in Facility Agriculture and Its Influencing Factors].

The aim of this study was to apply phosphorus fertilizer scientifically and reasonably and reduce the pollution risk to the facility agricultural environment. Taking the facility agriculture concentration area in Daxing District of Beijing as the research object, the phosphorus content in soil (0-100 cm) of the facility agriculture profile with different planting years was measured and analyzed to explore the characteristics of phosphorus accumulation, migration, and transformation. The results showed that the contents of total phosphorus and available phosphorus in the surface soil of facility agriculture varied widely, which was significantly higher than that in the surrounding grain field soil, which was mainly related to the amount of phosphorus applied by farmers in different planting years. With the increase in soil depth, the contents of total phosphorus and available phosphorus decreased gradually, showing surface aggregation ω (total phosphorus) ranging from 0.38 to 2.58 g·kg-1 and ω (available phosphorus) ranging from 1.60 to 256.00 mg·kg-1. With the increase in planting years, the contents of soil total phosphorus and available phosphorus first increased and then decreased, reached a peak in approximately 15 years, then gradually decreased, tended to be stable, and generally remained at a high level. Inorganic phosphorus was mainly concentrated in the surface soil of the facility agriculture, in which Ca-P accounted for the largest proportion of inorganic phosphorus, up to 98.38%; Ca10-P was the main form of Ca-P, up to 78.70% of Ca-P, and Ca2-P accounted for the smallest proportion, only 9.50% of Ca-P. The contents of different forms of inorganic phosphorus showed the vertical distribution characteristics of enrichment in the surface soil and a decrease downward. There were differences in the proportion of different forms of inorganic phosphorus to total phosphorus in different soil depths, in which the change in Ca-P was obvious, whereas the change in Fe-P and 0-P was not significant, indicating that the migration and transformation of Fe-P and O-P in the facility agricultural soil was poor, and the migration and transformation of inorganic phosphorus was mainly Ca-P. According to the correlation and path analysis, the direct path coefficient of Ca2-P to available phosphorus was the largest (0.787), which was not only the main source of soil available phosphorus but also the main form of inorganic phosphorus migration and transformation. Under the condition of protected cultivation, soil phosphorus showed a large accumulation trend, the availability of Ca10-P was low, and the accumulation was large. How to improve this portion of phosphorus sources is the key to the management of protected soil phosphorus.

Improvement in water pollution control alters nutrient stoichiometry of Guanting Reservoir near Beijing, North China.

Significant improvement in wastewater treatment is the most effective way for eutrophication control, especially in semiarid regions. However, its effect on the nutrient status and stoichiometry of the receiving water body has remained poorly considered and understood at broad temporal scales. Taking Guanting Reservoir (GR) in Hebei-Beijing (P. R. China) as an example, we present a study that links a continuous monitoring dataset for GR with corresponding estimates of human-induced nutrient discharges in its watershed from the year 2006 to 2019. We find that current GR belongs to strict P limitation and the faster decrease of TP than TN concentrations and continuous increase of TN/TP mass ratios in GR are attributed to the water restoration investment-induced declining of nutrient loadings. The improved municipal wastewater treatment capacity is mainly responsible for these significant changes, due to the higher removal efficiency of TP than TN in municipal wastewater. Given the potential ecological impact on aquatic biodiversity as well as ecosystem function of changes in TN/TP ratios and higher retention rate of TP (97.4%) compared with TN (93.1%) in GR, our findings highlight that future strategy for water pollution control should not only concentrate on more nutrient reduction efficiencies but attach importance to their stoichiometric balance to reduce the potential risk of phytoplankton blooms and toxin production during the water quality recovery of lakes or reservoirs.

Health Literacy and Health-Related Quality of Life in Beijing Adolescents: A Path Analysis.

BACKGROUND: Health literacy is a critical driver of achieving an equitable world for every child and adolescent. Although the relationship between health literacy and health-related quality of life (HRQoL) has been documented, little is known among adolescents. In addition, due to lack of theory-driven empirical research, it remains unknown about the full relationship between health literacy, its antecedents, and HRQoL. OBJECTIVE: This study aimed to apply Manganello's framework to investigate how health literacy was associated with its antecedents and HRQoL in Beijing secondary students. METHODS: A cross-sectional study was conducted with 650 students in years 7 to 9 from four secondary schools in Beijing. Based on Manganello's health literacy framework, a self-administered questionnaire was used to collect information on health literacy, its antecedents (i.e., sociodemographics, self-efficacy, social support, school and community environment), and HRQoL. The 8-item Health Literacy Assessment Tool was used to measure health literacy (score range 0-37), and the KIDSCREEN-10 was used to measure HRQoL (score range 10-50). Path analysis was conducted to examine the mediating role of health literacy in the relationship between its antecedents and HRQoL. KEY RESULTS: Overall, the average score of students' health literacy and HRQoL was 26.37 (±5.89) and 37.49 (±5.78), respectively. Health literacy was positively correlated with HRQoL (r = 0.36, p < .01). In the final path model, health literacy was not associated with HRQoL. However, students' social support, school environment, and community environment were associated with HRQoL. Health literacy was affected by self-efficacy, social support, and school environment (all p < .05). CONCLUSIONS: A range of intrapersonal, interpersonal, and environmental factors were associated with health literacy and HRQoL. A holistic approach is needed to improve health literacy and HRQoL through multilevel intervention strategies such as increasing personal self-efficacy, promoting social support, and creating positive environments. [HLRP: Health Literacy Research and Practice. 2022;6(4):e300-e309.] Plain Language Summary: We investigated how health literacy was related to its influencing factors and HRQoL among Beijing secondary students in years 7 to 9. Health literacy and HRQoL were independent outcomes affected by a range of social-ecological factors including self-efficacy, social support, and perceptions of school and community environments.

[International academic exchange in China in medical history in the 1980s：An Interview with].

Li Jingwei is one of the first experts on medical history philology in New China. He studied under Chen Bangxian and then began to work in the field of medical history philology in Beijing. He had several meetings and academic discussions with Professor Joseph Needham, a well-known scientist in the history of science, technology and medicine. In the 1980s, as a representative in the field of medical history in China, he participated in meetings for academic exchange with scholars from Thailand, Japan, Germany and the United States, through seminars and conferences such as the Thailand Chinese Academic Exchange Seminar in 1983, the Seminar of the 150th Anniversary of The American Association for the Advancement of Science in 1984, the 86th Annual Conference of Japanese Medical History Society in 1985, and the International Chinese Science and Technology History Seminar in the UK in 1990. In these seminars, he made friends with scholars, such as Manfred Porkert, Saburo Miyashita and Wu Yanhe. He witnessed and participated in international academic exchanges in the beginning of the reform and opening-up in China.

[Analysis of Pollution Characteristics and Sources of Rainfall Runoff from Roofs in the Central District of Beijing].

The rainwater and rainfall runoff of roofs in the central district of Beijing from June to September in 2019 were sampled and analyzed to study the characteristics of the water quality, the first flush effect, and the main influential factors and sources of pollutants. The results showed that the roof runoff was seriously polluted by total nitrogen, ammonia nitrogen, chemical oxygen demand, and total suspended solids whose event mean concentration (EMC) exceeded the fifth level of environmental quality standards for surface water (GB 3838-2002) (the EMC of suspended solids exceeded the second level of discharge standard of pollutants for municipal wastewater treatment plants (GB 18918-2002)). The rainwater was relatively less polluted than the rainfall runoff, but the EMC of ammonia nitrogen and total nitrogen of the rainwater also exceeded the standard in some rainfall events. The first flush intensity of the rainfall runoffs was between weak and medium. The sequence of strength of the first flush of different pollutants was ammonia nitrogen>total suspended solids>chemical oxygen demand>total nitrogen>mercury>zinc>total phosphorus>lead. The concentration of total suspended solids, chemical oxygen demand, and total phosphorus in roof runoff were significantly positively correlated with the length of rainfall and the dry period and negatively correlated with the rainfall intensity. According to the results of principal component analysis, the main pollutant in rainwater was nitrogen emitted by vehicles, and the main pollutants in roof runoffs were suspended solids, organic matters, and phosphorus pollutants released from the aging of roofing materials and the corrosion of metal down pipes.

Response of macroinvertebrate community to water quality factors and aquatic ecosystem health assessment in a typical river in Beijing, China.

Healthy aquatic ecosystems can offer basic ecological services for the sustainable development of humans and society. Water quality greatly influences the macroinvertebrate community in aquatic ecosystems and can alter the aquatic ecosystem's health status. However, the quantitative relationship between macroinvertebrate community and water quality factors in rivers remains unclear, particularly in urban rivers, which are strongly affected by human activities. Therefore, a new framework for the quantitative analysis between macroinvertebrate community and key water quality driving factors was developed in the study, meanwhile, the aquatic ecosystem health conditions were evaluated and validated by different methods. The framework was applied to a typical urban river, the North Canal River, which is regarded as the "mother river" of Beijing. Combined with the redundancy analysis (RDA) and the threshold indicator taxa analysis (TITAN), the water quality driving factors and their indicator species were identified and the corresponding response threshold was determined. Based on the benthic index of biotic integrity (B-IBI), the multi-metric rapid bioassessment method, and the biological monitoring working party (BMWP) score, the aquatic ecosystem health condition in the basin was comprehensively evaluated. The results show that fluoride, biochemical oxygen demand, ammonia-nitrogen and total phosphorus were the key water quality driving factors influencing the community structure of macroinvertebrates. Four indicator species of ammonia-nitrogen were identified by the TITAN method with a threshold range of 1.09-6.94 mg L-1, and three indicator species of total phosphorus were identified with a threshold range of 0.48-1.27 mg L-1. According to the results of the aquatic ecosystem health assessment, the river ecosystem was generally unhealthy and the upstream was better than downstream; the health condition in the mountainous areas of Changping district was the best, while that in Chaoyang district and the central city area was the worst. The framework could provide a strong basis for ecological restoration and pollution control of the urban rivers and become an important tool for the rehabilitation of aquatic ecosystems.

[Overview on diagnosis and treatment of oral diseases in the Qing Royal Court].

The remained documents and archives show that the history of diagnosis and treatment of oral diseases in royal court of the Qing Dynasty was over 200 years. The departmental system of medical care in the Qing Royal Court was inherited from former Ming Dynasty. Although the departments in the system changed over reigns, the Department of Dentistry exist all the time. In a set of historical records of 38 medical cases opened to the public, the documented symptoms and diseases, in the sense of modern medical science, included periodontitis, oral mucosal diseases, dental caries, parotiditis, etc., and the patients involved various ranks in the court, showing that oral diseases were common in the Qing Royal Court. The royal doctors ranked variedly and the medication they used was diverse. Medical fuming or steaming and medical heating were some distinctive methods among the treatments. In 1600s, the western modern medical science started to be introduced into China. In the reign of Kangxi Emperor (1700s), many western doctors were employed by the royal court and they engaged in the treatment of oral diseases. The late Qing Dynasty appeared the second peak that western doctors came into China. In 1898, Dr. Jingrong Chen, a dentist who possessed knowledge of modern dentistry in Beijing city, set up a dental clinic in the royal court and gave treatment to patients in the royal members and high-ranking officials.

A time-series analysis on generalized additive model for atmospheric pollen concentration and the number of visits of allergic conjunctivitis, Beijing, China.

The objective of this study is to investigate the correlation between atmospheric pollen concentration and daily visits for allergic conjunctivitis. Daily counts of outpatient visits for allergic conjunctivitis, atmospheric pollen concentration, and meteorological data during pollen season of 2018 and 2019 were collected from Beijing Shijitan Hospital, China. A time-series analysis on generalized additive model with Poisson distribution was used to estimate the relationship between pollen concentration and visits for allergic conjunctivitis, after controlling for the time trend, weather variables, day of the week, and holiday effect. The RStudio was used to generate Spearman correlation coefficients and then to plot the lag-response curves for specific and incremental cumulative effects of relative risk (RR). There was a moderate positive correlation between pollen concentration and visits for allergic conjunctivitis, and Spearman's correlation coefficient was 0.521 in 2018 and 0.515 in 2019 (P<0.01). The specific cumulative effect peak associated with per 10 grains/kmm2 increases of atmospheric pollen concentration was within 0 day, and the lag time was 8 days(2018, 2019). The incremental cumulative effect peak associated with per 10 grains/kmm2 increases of atmospheric pollen concentration occurred on lag day 10 (2018) and lag day 8 (2019), and the lag time was 14 days (2018) and 20 days (2019). Elevated concentrations of pollen increase the risk of allergic conjunctivitis with a time lag effect.

[Analysis of the current status and related factors of oral nutritional supplements intake among 18-79 years old in Beijing in 2017].

Objective: To understand the current status of taking nutrient supplements for residents aged 18 to 79 years old in Beijing and its related factors. Methods: Data were gathered from the 2017 Beijing Non-communicable and Chronic Disease Surveillance Program. Multiple classified cluster sampling method was used, and participants aged 18-79 were sampled from 16 districts. The questionnaire included chronic diseases and related risk factors, health knowledge, and oral nutritional supplements within 12 months. Multivariate logistic regression models were established to analyze associated factors that affect the intake of nutrient supplements. Results: The weighted prevalence of supplements use was 13.1% among 12 696 subjects within the past 12 months. The proportions of multivitamins (4.7%), B vitamins (4.5%), and folic acid (3.2%) were higher. The prevalence of supplement use of young people (18-39 years old) and the elderly (60-79 years old) was higher than middle-aged people (40-59 years old) (χ2=54.09, P<0.001). Except for the age group of 70-79 years old, the consumption rate of women was significantly higher than that of men (P<0.05). After adjusting age and sex, among patients with hypertension, diabetes, or dyslipidemia, the control rates of blood pressure, glucose and lipids of patients who take nutrient supplements were higher than those who do not (P<0.05). And participants who took nutrient supplements had a more heightened awareness rate of health knowledge, such as the hazards of smoking and second-hand smoke, and recommended amount of salt per day (P<0.001). The multi-factor logistic analysis found that nutrient supplement-related factors include women, old age, higher education level, living in urban, insufficient physical activity, sleeping problems, active physical examination, blood pressure control among patients, and health knowledge (P<0.05). Conclusions: The factors of nutrient supplements use were related to sex, age, education level, health status, and health literacy. We should pay attention to key populations and guide them to establish the correct concept of taking nutrient supplements.

[Visualized analysis of knowledge map for traditional Chinese medicine prevention and treatment of pulmonary nodules based on CiteSpace].

This study aims to analyze the current status and development trend of the prevention and treatment of pulmonary nodules(PN) with traditional Chinese medicine(TCM) based on knowledge map and to provide both references and suggestions for future research directions. CNKI, Wanfang, VIP, and SinoMed were searched for relevant papers from the inception to December 31, 2021. Eligible articles were included according to the inclusion and exclusion criteria. The line chart was drawn based on the annual publication volume of articles, and the research interests of this field were learned. The knowledge maps of prevention and treatment of PN with TCM were drawn in CiteSpace 5.8.R1, and the authors, institutions, contents, and hotspots were analyzed. A total of 122 articles were included and the line chart demonstrated that the annual publication volume has been rising since 2018. According to the knowledge maps, the most prolific author was ZHANG Xiao-mei and there were four main research teams. Beijing University of Chinese Medicine and its affiliated hospitals were in a leading position in this field. The main research contents were disease, pathogenesis, and treatment, and the hotspots were data mining and TCM syndrome. The research on prevention and treatment of PN with TCM has become an increasing field of interest in recent years. In the future, the cross-regional cooperation and communication between research teams and institutions should be strengthened for more real-world studies and basic studies about the prevention and treatment of PN with TCM, so that the high-level evidence can be obtained and the underlying mechanisms of TCM formulae in the treatment of PN be clarified.

Analysis of the current status and related factors of oral nutritional supplements intake among 18-79 years old in Beijing in 2017 / 中华流行病学杂志

Objective: To understand the current status of taking nutrient supplements for residents aged 18 to 79 years old in Beijing and its related factors. Methods: Data were gathered from the 2017 Beijing Non-communicable and Chronic Disease Surveillance Program. Multiple classified cluster sampling method was used, and participants aged 18-79 were sampled from 16 districts. The questionnaire included chronic diseases and related risk factors, health knowledge, and oral nutritional supplements within 12 months. Multivariate logistic regression models were established to analyze associated factors that affect the intake of nutrient supplements. Results: The weighted prevalence of supplements use was 13.1% among 12 696 subjects within the past 12 months. The proportions of multivitamins (4.7%), B vitamins (4.5%), and folic acid (3.2%) were higher. The prevalence of supplement use of young people (18-39 years old) and the elderly (60-79 years old) was higher than middle-aged people (40-59 years old) (χ2=54.09, P<0.001). Except for the age group of 70-79 years old, the consumption rate of women was significantly higher than that of men (P<0.05). After adjusting age and sex, among patients with hypertension, diabetes, or dyslipidemia, the control rates of blood pressure, glucose and lipids of patients who take nutrient supplements were higher than those who do not (P<0.05). And participants who took nutrient supplements had a more heightened awareness rate of health knowledge, such as the hazards of smoking and second-hand smoke, and recommended amount of salt per day (P<0.001). The multi-factor logistic analysis found that nutrient supplement-related factors include women, old age, higher education level, living in urban, insufficient physical activity, sleeping problems, active physical examination, blood pressure control among patients, and health knowledge (P<0.05). Conclusions: The factors of nutrient supplements use were related to sex, age, education level, health status, and health literacy. We should pay attention to key populations and guide them to establish the correct concept of taking nutrient supplements.