RESUMO
BACKGROUND: Radial head arthroplasty (RHA) is commonly used for the treatment of comminuted radial head fractures. Indications as well as implant types continue to evolve. RHA has had good outcomes with midterm longevity. The literature is limited to small case series with varying implant types, and larger studies are needed to determine the optimal implant type and radial head diameter. METHODS: A retrospective analysis of RHA cases performed by 75 surgeons at 14 medical centers in an integrated health care system between 2006 and 2017 was completed. Patient demographics, comorbidities, implant type and head diameter, and indications for revision were recorded. Patients' in-person clinical visit data were recorded. Patients were also contacted via telephone at a minimum of 2 years to obtain abbreviated Disabilities of the Arm, Shoulder, and Hand questionnaire and Oxford scores. Implant survivorship was also captured within our integrated system. RESULTS: 405 cases met our inclusion criteria. Mean age was 51.5 ± 15.5 years (range 16-88 years) and more common in females (62%). Chart review and telephone follow-up was performed at a mean of 68.9 ± 31.5 months (range 24-146 months). Our study found that revision rate was positively correlated with increasing radial head diameter. A 26-mm head had 7.7 odds of revision compared to a size 18-mm head (95% confidence interval 1.2-150.1). More than 95% of revision cases were performed within the first 36 months of the index procedure. Obese patients had a significantly lower mean postoperative Oxford score (35.5) compared to controls (38.3) (P = .02). There was a significantly higher overall reoperation rate for terrible triad (18.4%) vs. isolated injuries (10.4%) (P = .04). There was no difference between Acumed Anatomic and Evolve radial head implants in overall reoperation, implant revision, postoperative range of motion, or patient-reported outcomes. CONCLUSIONS: Risk of revision is directly correlated with implanted radial head diameter. There were no differences in outcomes and complications between the 2 main implants used. Individuals who did not undergo a revision by 3 years' time tend to retain the implant. Terrible triad injuries had a higher all-cause reoperation rate than isolated radial head fractures, but no difference in the rate of RHA revision. These data reinforce the practice of downsizing radial head implant diameter.
Assuntos
Articulação do Cotovelo , Fraturas do Rádio , Feminino , Humanos , Adolescente , Adulto Jovem , Adulto , Pessoa de Meia-Idade , Idoso , Idoso de 80 Anos ou mais , Estudos Retrospectivos , Resultado do Tratamento , Articulação do Cotovelo/cirurgia , Rádio (Anatomia)/cirurgia , Rádio (Anatomia)/lesões , Fraturas do Rádio/cirurgia , Artroplastia , Amplitude de Movimento ArticularRESUMO
Distal radius fractures are the most common type of upper limb fractures in adults. Non-union after distal radius fracture is rare, serious and unpredictable. The aim of our paper is to analyse the clinical and radiological outcomes of bone grafting and Sauvé-Kapandji Procedures for the treatment of aseptic distal radius non-union. We enrolled 13 patients with distal radius aseptic non-union. The following parameters were evaluated: The surgical time, elbow, forearm and wrist range of motion, the subjective quality of life and the wrist function measured by Quick Disabilities of the Arm, Shoulder and Hand (QuickDASH), Pain Visual Analogic Score (VAS) and the complication rate. Bone union was measured using the radiographic union score as described by Radiographic Union Score (RUS). The evaluation endpoint was set at 24 months after surgery. All patients achieved fracture union. Grip strength improved by 12.4 kg. There was also improvement in wrist flexion, in wrist extension, and forearm pronosupination. These ranges of motion and grip strength improvements were statistically significant. Only 6 patients returned to full activity. This surgical technique represents a reliable alternative for treatment of distal radius aseptic non-unions. Further studies are needed to assess the long-term clinical results of this surgical procedure.
Assuntos
Fraturas do Rádio , Rádio (Anatomia) , Fixação Interna de Fraturas , Humanos , Qualidade de Vida , Rádio (Anatomia)/diagnóstico por imagem , Rádio (Anatomia)/cirurgia , Fraturas do Rádio/diagnóstico por imagem , Fraturas do Rádio/cirurgia , Amplitude de Movimento Articular , Resultado do Tratamento , Articulação do Punho/diagnóstico por imagem , Articulação do Punho/cirurgiaRESUMO
We investigate the problem of achieving robust control of hand prostheses by the electromyogram (EMG) of transradial amputees in the presence of variable force levels, as these variations can have a substantial impact on the robustness of the control of the prostheses. We also propose a novel set of features that aim at reducing the impact of force level variations on the prosthesis controlled by amputees. These features characterize the EMG activity by means of the orientation between a set of spectral moments descriptors extracted from the EMG signal and a nonlinearly mapped version of it. At the same time, our feature extraction method processes the EMG signals directly from the time-domain to reduce computational cost. The performance of the proposed features is tested on EMG data collected from nine transradial amputees performing six classes of movements each with three force levels. Our results indicate that the proposed features can achieve significant reductions in classification error rates in comparison to other well-known feature extraction methods, achieving improvements of ≈ 6% to 8% in the average classification performance across all subjects and force levels, when training with all forces.
Assuntos
Cotos de Amputação/fisiopatologia , Amputados/reabilitação , Membros Artificiais , Biorretroalimentação Psicológica/instrumentação , Eletromiografia/métodos , Mãos/fisiopatologia , Adulto , Amputação Cirúrgica , Biorretroalimentação Psicológica/métodos , Eletromiografia/instrumentação , Desenho de Equipamento , Análise de Falha de Equipamento , Feminino , Mãos/cirurgia , Humanos , Masculino , Pessoa de Meia-Idade , Contração Muscular , Rádio (Anatomia)/fisiopatologia , Rádio (Anatomia)/cirurgia , Reprodutibilidade dos Testes , Sensibilidade e Especificidade , Estresse Mecânico , Análise e Desempenho de Tarefas , Adulto JovemRESUMO
The use of periclavicular brachial plexus block as regional anaesthesia for surgical procedures on the upper extremity is common. However, the proximity of the pleura results in a risk of pneumothorax. Without ultrasound monitoring, the pneumothorax risk has been reported to be as high as 6.1%. We conducted a prospective, observational study to examine the risk of pneumothorax in 6366 ultrasound-guided periclavicular plexus blocks. All patients with a clinically manifest and radiologically confirmed pneumothorax were analysed. Clinically symptomatic pneumothorax occurred in four patients (0.06%; 95% CI 0.001-0.124), in three of them after a two-day latency period. Ultrasound guidance does therefore appear to reduce the risk of pneumothorax. Although all of the anaesthesiologists involved in the complications had previously performed fewer than 20 blocks, we are not able to confirm that a block experience ≤ 20 is a significant risk factor. Faulty image-setting, inability to obtain a view of the needle tip and inadequate supervision are likely to be important risk factors.
Assuntos
Plexo Braquial/diagnóstico por imagem , Bloqueio Nervoso/efeitos adversos , Pneumotórax/epidemiologia , Pneumotórax/etiologia , Ultrassonografia de Intervenção/métodos , Adulto , Braço/cirurgia , Exostose/cirurgia , Feminino , Gânglios Sensitivos/cirurgia , Humanos , Masculino , Pessoa de Meia-Idade , Agulhas/efeitos adversos , Bloqueio Nervoso/métodos , Placa Palmar/cirurgia , Estudos Prospectivos , Rádio (Anatomia)/cirurgia , Fatores de Risco , Fumar/efeitos adversos , Estimulação Elétrica Nervosa Transcutânea , Punho/cirurgia , Adulto JovemRESUMO
BACKGROUND: For congenital proximal radioulnar synostosis, both conservative and operative treatments have been described. Most of the studies describing surgical interventions are based on subjective evaluation of the forearm function and have used severe degree of forearm pronation as an indication for surgery. This study describes a single-staged rotational osteotomy of the proximal third ulna and distal third radius. The aim of the study was to assess the utility of the described surgical procedure by subjective and objective evaluations of the forearm function. METHODS: Forty-eight children with congenital proximal radioulnar synostosis were evaluated by subjective and objective assessments and were followed up prospectively. Subjective evaluation consisted of a set of 12 questions regarding the basic activities of life. Objective evaluation was made using the Jebsen-Taylor hand-function test and a classification system used by Failla and colleagues for 15 tasks described by Morrey and colleagues. Eleven children were treated conservatively. Thirty-six children underwent a single-staged rotational osteotomy of the proximal third ulna and distal third radius. After surgery, the evaluations were repeated. The mean age at surgery was 8.6±3.7 years, and the mean postoperative follow-up period was 54±13 months. RESULTS: All operated forearms showed a statistically significant improvement in functioning after surgery as per the subjective and objective evaluations. The mean time taken to carry out all activities before surgery was 47.7+10.0 seconds, which significantly reduced to 33.3+6.6 seconds after surgery (P=0.0001) as per the results of the Jebsen-Taylor hand-function test. All good (n=19) and fair (n=11) results were converted to excellent (n=30) after surgery as per the modified Failla classification. There were no neurovascular injuries as compared with other published techniques. Only 1 child had delayed union, and 1 had persistent dorsal angulation at the radial osteotomy site. CONCLUSIONS: For patients with congenital radioulnar synostosis and pronation deformity interfering with function and quality of life, the single-staged rotational osteotomy of the radius and ulna is a good alternative procedure. LEVEL OF EVIDENCE: Level IV--therapeutic.
Assuntos
Moldes Cirúrgicos , Osteotomia/métodos , Rádio (Anatomia)/anormalidades , Autorrelato , Sinostose/diagnóstico por imagem , Sinostose/cirurgia , Ulna/anormalidades , Adolescente , Criança , Pré-Escolar , Estudos de Coortes , Feminino , Hospitais Pediátricos , Humanos , Masculino , Cuidados Pós-Operatórios/métodos , Pronação/fisiologia , Estudos Prospectivos , Qualidade de Vida , Radiografia , Rádio (Anatomia)/diagnóstico por imagem , Rádio (Anatomia)/cirurgia , Recuperação de Função Fisiológica , Índice de Gravidade de Doença , Supinação/fisiologia , Resultado do Tratamento , Ulna/diagnóstico por imagem , Ulna/cirurgiaRESUMO
OBJECTIVE: To explore the clinical effects of the manipulation reduction combined with small splint fixation for the treatment of fresh closed fracture of radius for shorten hospital stays and reduce medical cost. METHODS: From July 2007 to December 2009, 200 patients (ranged the age from 40 to 80 years) with distal radius comminute fracture were treated and divided into CP group (including 21 males and 79 females, with a mean age of (62.98 +/- 0.85) years), and control group (including 20 males and 80 females, with a mean age of (63.19 +/- 0.88) years). All patients were treated manipulation reduction combined with small-splint fixation, control group removed small-splint 30 days after treatment, CP group removed 25 days after treatment. Two groups were checked by X-ray and took traditional chinese medicine (taking Yuanhu tablets, Chuangshangning tablets on the early stage; Guixiangzhenggu pill was taken on the middle stage; Shuanglongjie gu pill on the late stage), functional exercise was guided after removing of small splint. The condition of reduction and position of bone were evaluated and Gartland-Werlley scale was used to evaluate the function of wrist joint. RESULTS: Treatment time in CP group was decreased from (30.08 +/- 3.06) to (25.06 +/- 1.07) days; treatment cost in CP group was decreased from (2 100.00 +/- 332.12) to (1 644.00 +/- 125.20) Yuan. There was no significant difference in reduction and function recover of wrist joint between two groups. The results showed the effects of TCM clinic can be promised. CONCLUSION: Clinical pathway for outpatient can promote standardization of outpatient, short treatment time less medical economic burden, and worth widely used.
Assuntos
Fixação Interna de Fraturas/métodos , Fraturas Fechadas/cirurgia , Fraturas do Rádio/cirurgia , Adulto , Idoso , Idoso de 80 Anos ou mais , Estudos de Casos e Controles , Feminino , Fixação Interna de Fraturas/instrumentação , Humanos , Masculino , Pessoa de Meia-Idade , Rádio (Anatomia)/cirurgia , ContençõesRESUMO
PURPOSE: This study tested the hypothesis that early integration of plateau root form endosseous implants is significantly affected by surgical drilling technique. MATERIALS AND METHODS: Sixty-four implants were bilaterally placed in the diaphysial radius of 8 beagles and remained 2 and 4 weeks in vivo. Half the implants had an alumina-blasted/acid-etched surface and the other half a surface coated with calcium phosphate. Half the implants with the 2 surface types were drilled at 50 rpm without saline irrigation and the other half were drilled at 900 rpm under abundant irrigation. After euthanasia, the implants in bone were nondecalcified and referred for histologic analysis. Bone-to-implant contact, bone area fraction occupancy, and the distance from the tip of the plateau to pristine cortical bone were measured. Statistical analyses were performed by analysis of variance at a 95% level of significance considering implant surface, time in vivo, and drilling speed as independent variables and bone-to-implant contact, bone area fraction occupancy, and distance from the tip of the plateau to pristine cortical bone as dependent variables. RESULTS: The results showed that both techniques led to implant integration and intimate contact between bone and the 2 implant surfaces. A significant increase in bone-to-implant contact and bone area fraction occupancy was observed as time elapsed at 2 and 4 weeks and for the calcium phosphate-coated implant surface compared with the alumina-blasted/acid-etched surface. CONCLUSIONS: Because the surgical drilling technique did not affect the early integration of plateau root form implants, the hypothesis was refuted.
Assuntos
Implantação Dentária Endóssea/métodos , Implantes Dentários , Planejamento de Prótese Dentária , Osseointegração/fisiologia , Osteotomia/métodos , Condicionamento Ácido do Dente/métodos , Ligas , Óxido de Alumínio/química , Animais , Fosfatos de Cálcio/química , Materiais Revestidos Biocompatíveis/química , Ligas Dentárias/química , Corrosão Dentária/métodos , Diáfises/patologia , Diáfises/cirurgia , Cães , Masculino , Osteogênese/fisiologia , Gases em Plasma/química , Rádio (Anatomia)/patologia , Rádio (Anatomia)/cirurgia , Cloreto de Sódio , Propriedades de Superfície , Irrigação Terapêutica , Fatores de Tempo , Titânio/química , Cicatrização/fisiologiaRESUMO
BACKGROUND: Chemical modification of implant surface is typically associated with surface topographic alterations that may affect early osseointegration. This study investigates the effects of controlled surface alterations in early osseointegration in an animal model. METHODS: Five implant surfaces were evaluated: 1) alumina-blasting, 2) biologic blasting, 3) plasma, 4) microblasted resorbable blasting media (microblasted RBM), and 5) alumina-blasting/acid-etched (AB/AE). Surface topography was characterized by scanning electron microscopy and optical interferometry, and chemical assessment by x-ray photoelectron spectroscopy. The implants were placed in the radius of six dogs, remaining 2 and 4 weeks in vivo. After euthanization, specimens were torqued-to-interface failure and non-decalcified-processed for histomorphologic bone-implant contact, and bone area fraction-occupied evaluation. Statistical evaluation was performed by one-way analysis of variance (P <0.05) and post hoc testing by the Tukey test. RESULTS: The alumina-blasting surface presented the highest average surface roughness and mean root square of the surface values, the biologic blasting the lowest, and AB/AE an intermediate value. The remaining surfaces presented intermediate values between the biologic blasting and AB/AE. The x-ray photoelectron spectroscopy spectra revealed calcium and phosphorus for the biologic blasting and microblasted RBM surfaces, and the highest oxygen levels for the plasma, microblasted RBM, and AB/AE surfaces. Significantly higher torque was observed at 2 weeks for the microblasted RBM surface (P <0.04), but no differences existed between surfaces at 4 weeks (P >0.74). No significant differences in bone-implant contact and bone area fraction-occupied values were observed at 2 and 4 weeks. CONCLUSION: The five surfaces were osteoconductive and resulted in high degrees of osseointegration and biomechanical fixation.
Assuntos
Implantes Dentários , Planejamento de Prótese Dentária , Osseointegração/fisiologia , Implantes Absorvíveis , Condicionamento Ácido do Dente/métodos , Óxido de Alumínio/química , Animais , Materiais Biocompatíveis/química , Fenômenos Biomecânicos , Cálcio/análise , Materiais Revestidos Biocompatíveis/química , Corrosão Dentária/métodos , Análise do Estresse Dentário/instrumentação , Cães , Processamento de Imagem Assistida por Computador , Interferometria , Luz , Teste de Materiais , Microscopia Eletrônica de Varredura , Modelos Animais , Fósforo/análise , Espectroscopia Fotoeletrônica , Gases em Plasma/química , Rádio (Anatomia)/cirurgia , Estresse Mecânico , Propriedades de Superfície , Fatores de Tempo , TorqueRESUMO
OBJECTIVE: To evaluate the early bone response to plateau root form dental implants with 4 different surface treatments. STUDY DESIGN: Surface treatments comprised (n = 12 each): as-machined (M), alumina-blasted/acid-etched (AB/AE), alumina-blasted/acid-etched + nanothickness bioceramic coating (Nano), and plasma-sprayed calcium phosphate (PSCaP). Implants were placed in the radius diaphyses of 12 beagle dogs, remaining in vivo for 3 and 5 weeks. After euthanasia, the implants were subjected to torque to interface fracture and subsequently nondecalcified for histomorphology. Statistical analysis was performed by a GLM analysis of variance model at 5% significance level. RESULTS: Torque to interface fracture was significantly greater for the PSCaP group than for other groups (P < .001). Histomorphologic analysis showed woven bone formation around all implant surfaces at 3 weeks, and its replacement by lamellar bone at 5 weeks. Time in vivo did not affect torque measures. CONCLUSION: The PSCaP surface increased the early bone biomechanical fixation of plateau root form implants.
Assuntos
Corrosão Dentária/métodos , Implantes Dentários , Planejamento de Prótese Dentária , Osseointegração/fisiologia , Rádio (Anatomia)/fisiopatologia , Condicionamento Ácido do Dente , Ligas , Óxido de Alumínio/química , Animais , Fenômenos Biomecânicos , Remodelação Óssea/fisiologia , Fosfatos de Cálcio/química , Cerâmica/química , Materiais Revestidos Biocompatíveis/química , Ligas Dentárias/química , Cães , Masculino , Nanoestruturas/química , Osteogênese/fisiologia , Osteotomia , Rádio (Anatomia)/cirurgia , Estresse Mecânico , Propriedades de Superfície , Fatores de Tempo , Titânio/química , TorqueRESUMO
A radial segmental defect model of a rabbit was used to study the restoration effect on defects treated with chitosan-coated pressed calcium sulfate pellets combined with recombinant human bone morphogenetic protein-2 (rhBMP-2), coated pressed calcium sulfate pellets, and uncoated pressed calcium sulfate pellets. Nothing was implanted in the control group. After 4, 8, and 12 weeks, the results indicated that coated pressed calcium sulfate pellets combined with rhBMP-2 and coated pressed calcium sulfate pellets facilitated new bone formation on defected bones and that, particularly, the coated pressed calcium sulfate pellets combined with rhBMP-2 was more effective than the coated pressed calcium sulfate pellet. Histologic and tetracycline fluorimetric findings showed that the osteogenesis mechanism of chitosan-coated pressed calcium sulfate pellets is membrane bone formation, and the pellets showed slightly slower resorption that closely coincides with the growth rate of new bone.
Assuntos
Doenças Ósseas/cirurgia , Substitutos Ósseos/uso terapêutico , Sulfato de Cálcio/uso terapêutico , Quitosana/uso terapêutico , Materiais Revestidos Biocompatíveis/uso terapêutico , Osteogênese/efeitos dos fármacos , Implantes Absorvíveis , Animais , Densidade Óssea/efeitos dos fármacos , Doenças Ósseas/patologia , Medula Óssea/patologia , Proteína Morfogenética Óssea 2 , Proteínas Morfogenéticas Ósseas/administração & dosagem , Proteínas Morfogenéticas Ósseas/uso terapêutico , Calcificação Fisiológica/efeitos dos fármacos , Tecido Conjuntivo/patologia , Diáfises/patologia , Diáfises/cirurgia , Modelos Animais de Doenças , Corantes Fluorescentes , Fluorometria , Humanos , Coelhos , Rádio (Anatomia)/patologia , Rádio (Anatomia)/cirurgia , Proteínas Recombinantes/administração & dosagem , Proteínas Recombinantes/uso terapêutico , Estresse Mecânico , Tetraciclina , Fatores de Tempo , Fator de Crescimento Transformador beta/administração & dosagem , Fator de Crescimento Transformador beta/uso terapêuticoRESUMO
OBJECTIVE: To compare the effects of different calcium sulfate pellets made by different methods in treating segmental defect of bone. METHODS: Eighty New Zealand white rabbits underwent cutting off a segment in the middle part of radius so as to establish models of radial segmental defect, and than were divided into 4 groups: Group A as control group, Group B with calcium sulfate pellet made by routine method implanted into the defect, Group C with chitosan coated pressed calcium sulfate pellet implanted into the defect, and Group D with chitosan coated pressed calcium sulfate pellet combined with recombinant human bone morphogenetic protein (rhBMP)-2 implanted into the defect: X-ray photography was done every 4 weeks to observe the new bone formation. Four, 8, and 12 weeks 5 rabbits from each group were killed. The defect segments with parts of normal bone at both ends were cut off to undergo fluorescence microscopy and biomechanic three point bending test. RESULTS: X-ray photography and histological examination showed that new bone formation of cortex and reconstruction of marrow cavity were seen in Groups D and C, especially in Group D. The new bone mineralization rate of Group D was significantly higher than that of Group C (P<0.05) which was significantly higher than that of Group B (P<0.01). The anti-bending strength ratio of Group D was (47.5%+/-2.1%, significantly higher than that of Group C [(39.6+/-1.7)%, F=125.3, P<0.01], and the anti-bending strength ratios of Groups D and C were both significantly higher than those of Groups B and A [(23.6+/-3.3)% and (21.3+/-2.7)%]. CONCLUSION: Chitosan coated pressed calcium sulfate pellet shows relatively higher anti-bending strength and slightly slower resorption that closely coincide with the growth rate of new bone. It can be used to restore segmental bone defect, and particularly when combined with rhBMP-2.
Assuntos
Regeneração Óssea , Substitutos Ósseos/uso terapêutico , Sulfato de Cálcio/uso terapêutico , Animais , Sulfato de Cálcio/farmacologia , Implantes de Medicamento , Consolidação da Fratura/efeitos dos fármacos , Regeneração Tecidual Guiada , Coelhos , Rádio (Anatomia)/cirurgia , Engenharia Tecidual/métodosRESUMO
OBJECTIVE: To explore the effects of Yishen Zhuanggu decoction ([Chinese characters: see text], YSZGD) on the fracture healing and function of wrist joint in osteoporotic distal radius fractures (ODRF) of elderly patients. METHODS: Ninety patients of ODRF were treated with splint external fixation and YSZGD, including 28 males and 62 females, with an average age of 63 years (ranged, 61 to 91 years). According to AO classification, all the patients were classified as type A or B1. Among the patients, 80 patients had a type of Colles fracture,7 patients were with a type of Smith fracture,and 3 patients had a type of Barton fracture. They were randomly divided into three groups included TCM, Western medicine and control group (30 cases each group) after the fractures were fixed manually by splint. Patients in TCM group took YSZGD orally, one potion and two time each day; the patients in Western medicine group treated with Calcitonin (50 units, intramuscular, 2 times each week), Caltrate D (1 tablets, taken orally, one time each day) and Alfacalcidol Soft Capsules (0.5 units, taken orally, one time each day); and the patients in control group took no medicine. X-ray examination on the fractured wrist was taken at the 4, 6, 8, 12th weeks after treating to observe, the fracture healings, the evaluation of wrist function and comparision of curative effects were taken at the 2nd month. RESULTS: The fracture healing time in TCM group was 7.12 +/- 2.32 weeks and that in the Western medicine group was 9.25 +/- 3.05 weeks, showing significant differences between them (PC < 0.05), and that in the control group was 11.57 +/- 1.93 weeks which was longer thant in that in the two medicine groups (P < 0.05); According to Dienst wrist rating system, the excellent and good rates of three groups were 93.3%, 86.7% and 60% respectively which showing significant differences between medicine groups and control group (P < 0.05), and the curative effects of medicine groups were more excellent than that of control group through Ridit analysis. CONCLUSION: YSZGD can promote the fracture healing evidently and shorten the healing time, whose curative effect surpassed Western medicine and promoted the restoration of wrist function.
Assuntos
Medicamentos de Ervas Chinesas/uso terapêutico , Fixação de Fratura , Fraturas do Rádio/tratamento farmacológico , Fraturas do Rádio/cirurgia , Idoso , Idoso de 80 Anos ou mais , Conservadores da Densidade Óssea/uso terapêutico , Feminino , Humanos , Masculino , Rádio (Anatomia)/cirurgia , Resultado do TratamentoRESUMO
A chitosan-coated pressed calcium sulfate pellet combined with recombinant human bone morphogenetic protein 2 (rhBMP-2) has been developed with increased compressive strength and osteoinduction, but with a resorption profile only slightly slower than uncoated pellet. A radial segmental defect model of rabbit was used to study the restoration effect on defect treated with chitosan-coated pressed calcium sulfate pellet combined with rhBMP-2, coated pressed calcium sulfate pellet, and uncoated pressed calcium sulfate pellet. Nothing was implanted in the control group. After 4, 8, and 12 weeks, the results indicated that coated pressed calcium sulfate pellet combined with rhBMP-2 and coated pressed calcium sulfate pellet facilitated new bone formation on defected bone and that particularly the former was more effective than the latter.
Assuntos
Doenças Ósseas/cirurgia , Proteínas Morfogenéticas Ósseas/uso terapêutico , Substitutos Ósseos/uso terapêutico , Sulfato de Cálcio/uso terapêutico , Quitosana/uso terapêutico , Materiais Revestidos Biocompatíveis/uso terapêutico , Osteogênese/efeitos dos fármacos , Rádio (Anatomia)/cirurgia , Proteínas Recombinantes/uso terapêutico , Fator de Crescimento Transformador beta/uso terapêutico , Animais , Doenças Ósseas/patologia , Medula Óssea/efeitos dos fármacos , Medula Óssea/patologia , Proteína Morfogenética Óssea 2 , Calo Ósseo/efeitos dos fármacos , Calo Ósseo/patologia , Força Compressiva , Tecido Conjuntivo/efeitos dos fármacos , Tecido Conjuntivo/patologia , Modelos Animais de Doenças , Osteoblastos/efeitos dos fármacos , Osteoblastos/patologia , Maleabilidade , Coelhos , Rádio (Anatomia)/patologia , Fatores de TempoRESUMO
OBJECTIVE: To investigate the outcome of manipulative reduction and splint fixation for treatment of middle and lower fractures of ulnar and radius. METHODS: Sixty-eight patients with lower segment fractures of ulnar and radius included 46 male and 22 female, aged from 1 to 26 years. The course was from 10 min to 1 week. There were 39 cases in right and 29 in left; 45 in inferior segment and 23 in middle segment. All cases were closed fractures. According to fracture displacement, different methods of manipulation and splint or plaster splint fixation were used to reduction and fixation. RESULTS: Sixty-eight patient were followed-up for 0.5 to 1 year (mean 8 months), the fractures were all healing. According to the effective evaluation criteria, the results were excellent in 57 cases, good in 11. X-ray film showed anatomic reduction in 38 cases, similar to anatomic reduction in 20, functional reduction in 10. CONCLUSIONS: Manipulative reduction and splint fixation for the treatment of the ulnar and radial bone fractures is a method of simple, minimally invasive, effective and functional advantages of quick recovery.
Assuntos
Fraturas Ósseas/terapia , Manipulações Musculoesqueléticas , Rádio (Anatomia)/lesões , Ulna/lesões , Adolescente , Adulto , Criança , Pré-Escolar , Fixadores Externos , Feminino , Seguimentos , Fixação de Fratura , Fraturas Ósseas/cirurgia , Fraturas Fechadas/cirurgia , Fraturas Fechadas/terapia , Humanos , Lactente , Masculino , Rádio (Anatomia)/cirurgia , Contenções , Ulna/cirurgiaRESUMO
Despite extensive experience with prosthetic replacement for the reconstruction of limbs following juxta-articular resection of tumours, there are few reports of prosthetic replacement of the distal radius. We present two cases of massive bone defects of the distal radius in which alumina ceramic prosthetic replacements were used. We evaluated the patients more than ten years after the procedure. Both patients had degenerative changes to the wrist. This, however, was not associated with pain or decreased function, and both had returned to their previous occupation after surgery. When a patient has a massive defect of the distal radius, reconstruction using a ceramic prosthesis is a reasonable alternative to using autograft. This method of treatment results in little pain, a moderate range of movement and satisfactory function.
Assuntos
Neoplasias Ósseas/cirurgia , Tumor de Células Gigantes do Osso/cirurgia , Próteses e Implantes , Rádio (Anatomia)/cirurgia , Óxido de Alumínio , Neoplasias Ósseas/diagnóstico por imagem , Cerâmica , Seguimentos , Tumor de Células Gigantes do Osso/diagnóstico por imagem , Humanos , Masculino , Pessoa de Meia-Idade , Radiografia , Articulação do Punho/cirurgiaRESUMO
El autor presenta su experiencia personal en el tratamiento de las fracturas inestables multifragmentarias de la extremidad distal del radio, mediante el uso de un triple enclavijado con férula-tutor externo de acero articulada multiperforada y yeso funcional. Durante 3 años se trataron en el Departamento de Ortopedia y Traumatología de la Clínica Regional de Sud de la ciudad de Río Cuarto 35 casos con este procedimiento. La edad promedio fue de 55 años, siendo del sexo femenino el 80 por ciento y un seguimiento promedio de 2 años. El porcentaje de buenos resultados (70 por ciento) está dado en poder enclavijar bien la estiloides radial, tratando en lo posible de tomar también algunos de los componentes mediales (palmar o dorsal) incluyendo la estiloides cubital para darle mayor y mejor estabilidad al "mosaico fracturario" y garantizar la movilidad precoz de la articulación radiocarpiana
Assuntos
Rádio (Anatomia)/cirurgia , Fixadores Externos , Fraturas Cominutivas , Ferula , Parafusos ÓsseosRESUMO
The use of capacitively coupled low-voltage signals for stimulation of osteogenesis has been reported in a variety of animal models. Electrically induced osteogenesis was investigated with a capacitively coupled electric field on a radius (distal-lateral orientation) osteotomy model, in conjunction with internal fixation and postoperative loading. Twelve adult horses of either sex were allotted to 2 groups of 6; 1 group was given electrical stimulation and the other served as controls. A low-voltage high-frequency capacitively coupled electrical signal was locally and continuously applied to the electrically stimulated group for 60 days through external, bare stainless steel surface electrodes which were placed on the skin in circuit with a small, portable power source. Harness compatibility and stimulator and battery durability were excellent. However, stainless steel electrodes required a rigid maintenance schedule to maintain consistent current levels. Synovial fluid evaluation demonstrated intra-articular inflammation (decreased viscosity, hyaluronic acid, and increased protein concentration) 1 week postoperatively that generally improved during subsequent weeks and no distinction between groups was observed at 60 days. Radiographically, there was no difference in the appearance of the healing process of control and that of stimulated horses during the 60 days. Angiography showed bridging blood vessels in both groups. Uptake of a bone seeking radiopharmaceutical peaked at 3 weeks in both groups and was 1.92 +/- 0.6 cps/pixel/mCi and 1.26 +/- 0.40 csp/pixel/mCi for control and stimulated horses, respectively. At any given observation period, uptake in the lesion area was greater in the control group. Ultimate strengths of trabecular bone in 60-day control radii and stimulated radii were 12.64 +/- 3.013 and 9.60 +/- 3.95 MN/m2, and the flexural moduli of elasticity were 698.0 +/- 423 and 402.0 +/- 523 MN/m2, respectively. Porosity index was similar for all specimens. Gross, histologic, and microradiographic evaluations indicated that controls healed more efficiently than stimulated horses. A capacitively coupled applied voltage of 2.2 V RMS (mean) producing a current of 17.32 mA (mean) did not stimulate sufficient bone production in a metaphyseal osteotomy model to affect the mechanical properties of the bone or accelerate the healing process.