Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 312
Filtrar
Mais filtros

Medicinas Complementares
Tipo de documento
Intervalo de ano de publicação
1.
Med Care ; 59(Suppl 3): S252-S258, 2021 06 01.
Artigo em Inglês | MEDLINE | ID: mdl-33976074

RESUMO

BACKGROUND: Congress has enacted 2 major pieces of legislation to improve access to care for Veterans within the Department of Veterans Affairs (VA). As a result, the VA has undergone a major transformation in the way that care is delivered to Veterans with an increased reliance on community-based provider networks. No studies have examined the relationship between VA and contracted community providers. This study examines VA facility directors' perspectives on their successes and challenges building relationships with community providers within the VA Community Care Network (CCN). OBJECTIVES: To understand who VA facilities partner with for community care, highlight areas of greatest need for partnerships in various regions, and identify challenges of working with community providers in the new CCN contract. RESEARCH DESIGN: We conducted a national survey with VA facility directors to explore needs, challenges, and expectations with the CCN. RESULTS: The most common care referred to community providers included physical therapy, chiropractic, orthopedic, ophthalmology, and acupuncture. Open-ended responses focused on 3 topics: (1) Challenges in working with community providers, (2) Strategies to maintain strong relationships with community providers, and (3) Re-engagement with community providers who no longer provide care for Veterans. CONCLUSIONS: VA faces challenges engaging with community providers given problems with timely reimbursement of community providers, low (Medicare) reimbursement rates, and confusing VA rules related to prior authorizations and bundled services. It will be critical to identify strategies to successfully initiate and sustain relationships with community providers.


Assuntos
Serviços de Saúde Comunitária/organização & administração , Redes Comunitárias/organização & administração , Pessoal de Saúde/psicologia , Política de Saúde , Parcerias Público-Privadas/organização & administração , Serviços de Saúde Comunitária/legislação & jurisprudência , Redes Comunitárias/legislação & jurisprudência , Pesquisas sobre Atenção à Saúde , Pessoal de Saúde/organização & administração , Acessibilidade aos Serviços de Saúde/legislação & jurisprudência , Acessibilidade aos Serviços de Saúde/organização & administração , Humanos , Avaliação das Necessidades , Parcerias Público-Privadas/legislação & jurisprudência , Pesquisa Qualitativa , Estados Unidos , United States Department of Veterans Affairs/legislação & jurisprudência , Serviços de Saúde para Veteranos Militares/legislação & jurisprudência
2.
Nutrients ; 13(4)2021 Apr 06.
Artigo em Inglês | MEDLINE | ID: mdl-33917383

RESUMO

As a major public health concern, childhood obesity is a multifaceted and multilevel metabolic disorder influenced by genetic and behavioral aspects. While genetic risk factors contribute to and interact with the onset and development of excess body weight, available evidence indicates that several modifiable obesogenic behaviors play a crucial role in the etiology of childhood obesity. Although a variety of systematic reviews and meta-analyses have reported the effectiveness of several interventions in community-based, school-based, and home-based programs regarding childhood obesity, the prevalence of children with excess body weight remains high. Additionally, researchers and pediatric clinicians are often encountering several challenges and the characteristics of an optimal weight management strategy remain controversial. Strategies involving a combination of physical activity, nutritional, and educational interventions are likely to yield better outcomes compared to single-component strategies but various prohibitory limitations have been reported in practice. This review seeks to (i) provide a brief overview of the current preventative and therapeutic approaches towards childhood obesity, (ii) discuss the complexity and limitations of research in the childhood obesity area, and (iii) suggest an Etiology-Based Personalized Intervention Strategy Targeting Childhood Obesity (EPISTCO). This purposeful approach includes prioritized nutritional, educational, behavioral, and physical activity intervention strategies directly based on the etiology of obesity and interpretation of individual characteristics.


Assuntos
Obesidade Infantil/terapia , Programas de Redução de Peso/métodos , Terapia Comportamental/métodos , Terapia Comportamental/organização & administração , Terapia Comportamental/tendências , Criança , Redes Comunitárias/organização & administração , Redes Comunitárias/tendências , Humanos , Terapia Nutricional/métodos , Terapia Nutricional/tendências , Educação de Pacientes como Assunto/métodos , Educação de Pacientes como Assunto/organização & administração , Educação de Pacientes como Assunto/tendências , Obesidade Infantil/epidemiologia , Obesidade Infantil/etiologia , Modalidades de Fisioterapia/organização & administração , Modalidades de Fisioterapia/tendências , Prevalência , Serviços de Saúde Escolar/organização & administração , Serviços de Saúde Escolar/tendências , Programas de Redução de Peso/organização & administração , Programas de Redução de Peso/tendências
4.
Age Ageing ; 49(4): 516-522, 2020 07 01.
Artigo em Inglês | MEDLINE | ID: mdl-32725209

RESUMO

Older people are particularly affected by the COVID-19 outbreak because of their vulnerability as well as the complexity of health organisations, particularly in the often-compartmentalised interactions between community, hospital and nursing home actors. In this endemic situation, with massive flows of patients requiring holistic management including specific and intensive care, the appropriate assessment of each patient's level of care and the organisation of specific networks is essential. To that end, we propose here a territorial organisation of health care, favouring communication between all actors. This organisation of care is based on three key points: To use the basis of territorial organisation of health by facilitating the link between hospital settings and geriatric sectors at the regional level.To connect private, medico-social and hospital actors through a dedicated centralised unit for evaluation, geriatric coordination of care and decision support. A geriatrician coordinates this multidisciplinary unit. It includes an emergency room doctor, a supervisor from the medical regulation centre (Centre 15), an infectious disease physician, a medical hygienist and a palliative care specialist.To organise an ad hoc follow-up channel, including the necessary resources for the different levels of care required, according to the resources of the territorial network, and the creation of a specific COVID geriatric palliative care service. This organisation meets the urgent health needs of all stakeholders, facilitating its deployment and allows the sustainable implementation of a coordinated geriatric management dynamic between the stakeholders on the territory.


Assuntos
Infecções por Coronavirus , Avaliação Geriátrica/métodos , Serviços de Saúde para Idosos , Pandemias , Administração dos Cuidados ao Paciente , Pneumonia Viral , Programas Médicos Regionais/organização & administração , Idoso , Betacoronavirus/isolamento & purificação , COVID-19 , Redes Comunitárias/organização & administração , Infecções por Coronavirus/epidemiologia , Infecções por Coronavirus/prevenção & controle , França/epidemiologia , Alocação de Recursos para a Atenção à Saúde/tendências , Serviços de Saúde para Idosos/ética , Serviços de Saúde para Idosos/organização & administração , Serviços de Saúde para Idosos/tendências , Humanos , Inovação Organizacional , Cuidados Paliativos/métodos , Pandemias/prevenção & controle , Administração dos Cuidados ao Paciente/ética , Administração dos Cuidados ao Paciente/organização & administração , Administração dos Cuidados ao Paciente/tendências , Pneumonia Viral/epidemiologia , Pneumonia Viral/prevenção & controle , SARS-CoV-2 , Web Semântica , Participação dos Interessados
5.
Healthc Pap ; 19(1): 11-18, 2020 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-32310749

RESUMO

Integrated healthcare models are being experimented with in many jurisdictions as a way to improve patient care and lower system costs. This commentary presents early lessons from one Ontario Health Team as it works towards new models of care. The authors recount early discussions on developing an integrated health services network, how funding for "winter surge initiatives" became an opportunity to test ideas and how these experiences are informing current planning. Some of the early lessons learned include the value of trusted relationships, moving care upstream and framing problems as collective challenges.


Assuntos
Planejamento em Saúde Comunitária/economia , Redes Comunitárias/organização & administração , Prestação Integrada de Cuidados de Saúde , Desenvolvimento de Programas , Prestação Integrada de Cuidados de Saúde/economia , Prestação Integrada de Cuidados de Saúde/organização & administração , Humanos , Ontário
6.
Br J Community Nurs ; 25(3): S20-S25, 2020 Mar 01.
Artigo em Inglês | MEDLINE | ID: mdl-32160063

RESUMO

Primary care networks (PCNs) were introduced in England in 2019 to bring about closer collaboration between general practice and community health services. The ambition is that greater collaboration between services will achieve better patient outcomes and reduce costs through more effective sharing of staff and resources. Wound care might be considered an ideal focus for PCNs, since general practice and community health services not only have a predominant role in the management of wounds, but variable and suboptimal practice continues and poor outcomes persist. This article investigates some ways in which PCNs might enable health-system changes that could improve the provision of wound care.


Assuntos
Redes Comunitárias/organização & administração , Atenção Primária à Saúde/organização & administração , Ferimentos e Lesões/terapia , Redes Comunitárias/normas , Inglaterra , Acessibilidade aos Serviços de Saúde , Humanos , Úlcera da Perna/terapia , Programas Nacionais de Saúde/organização & administração , Atenção Primária à Saúde/normas , Melhoria de Qualidade , Encaminhamento e Consulta , Varizes/terapia , Cicatrização , Ferimentos e Lesões/fisiopatologia
7.
Cancer Prev Res (Phila) ; 12(10): 701-710, 2019 10.
Artigo em Inglês | MEDLINE | ID: mdl-31427275

RESUMO

Self-sampling for human papillomavirus (HPV) testing is an alternative to physician sampling particularly for cervical cancer screening nonattenders. The GRECOSELF study is a nationwide observational cross-sectional study aiming to suggest a way to implement HPV-DNA testing in conjunction with self-sampling for cervical cancer screening in Greece, utilizing a midwifery network. Women residing in remote areas of Greece were approached by midwives, of a nationwide network, and were provided with a self-collection kit (dry swab) for cervicovaginal sampling and asked to answer a questionnaire about their cervical cancer screening history. Each sample was tested for high-risk (hr) HPV with the Cobas HPV test. HrHPV-Positive women were referred to undergo colposcopy and, if needed, treatment according to colposcopy/biopsy results. Between May 2016 and November 2018, 13,111 women were recruited. Of these, 12,787 women gave valid answers in the study questionnaire and had valid HPV-DNA results; hrHPV prevalence was 8.3%; high-grade cervical/vaginal disease or cancer prevalence was 0.6%. HrHPV positivity rate decreased with age from 20.7% for women aged 25-29 years to 5.1% for women aged 50-60 years. Positive predictive value for hrHPV testing and for HPV16/18 genotyping ranged from 5.0% to 11.6% and from 11.8% to 27.0%, respectively, in different age groups. Compliance to colposcopy referral rate ranged from 68.6% (for women 25-29) to 76.3% (for women 40-49). For women residing in remote areas of Greece, the detection of hrHPV DNA with the Cobas HPV test, on self-collected cervicovaginal samples using dry cotton swabs, which are provided by visiting midwives, is a promising method for cervical cancer secondary prevention.


Assuntos
Testes de DNA para Papilomavírus Humano , Programas de Rastreamento/organização & administração , Tocologia/organização & administração , Infecções por Papillomavirus/diagnóstico , Manejo de Espécimes/métodos , Displasia do Colo do Útero/diagnóstico , Neoplasias do Colo do Útero/diagnóstico , Adolescente , Adulto , Idoso , Colposcopia/estatística & dados numéricos , Redes Comunitárias/organização & administração , Redes Comunitárias/normas , Estudos Transversais , DNA Viral/análise , DNA Viral/genética , Autoavaliação Diagnóstica , Detecção Precoce de Câncer/métodos , Detecção Precoce de Câncer/normas , Detecção Precoce de Câncer/estatística & dados numéricos , Feminino , Grécia/epidemiologia , Testes de DNA para Papilomavírus Humano/métodos , Testes de DNA para Papilomavírus Humano/normas , Testes de DNA para Papilomavírus Humano/estatística & dados numéricos , Humanos , Ciência da Implementação , Programas de Rastreamento/métodos , Programas de Rastreamento/normas , Pessoa de Meia-Idade , Tocologia/métodos , Enfermeiros Obstétricos/organização & administração , Enfermeiros Obstétricos/normas , Enfermeiros Obstétricos/estatística & dados numéricos , Papel do Profissional de Enfermagem , Papillomaviridae/genética , Papillomaviridae/isolamento & purificação , Infecções por Papillomavirus/complicações , Infecções por Papillomavirus/epidemiologia , Infecções por Papillomavirus/patologia , População Rural/estatística & dados numéricos , Manejo de Espécimes/normas , Manejo de Espécimes/estatística & dados numéricos , Neoplasias do Colo do Útero/epidemiologia , Neoplasias do Colo do Útero/etiologia , Esfregaço Vaginal/métodos , Esfregaço Vaginal/estatística & dados numéricos , Adulto Jovem , Displasia do Colo do Útero/epidemiologia , Displasia do Colo do Útero/etiologia
8.
PLoS One ; 14(7): e0220107, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31344081

RESUMO

INTRODUCTION: La Maison Bleue is a community-based perinatal health and social centre in Montreal that provides services during pregnancy up to age five to families living in vulnerable contexts. The study aimed to describe: 1) the challenges and protective factors that affect the well-being of migrant families receiving care at La Maison Bleue; and 2) how La Maison Bleue strengthens resilience among these families. METHODS: We conducted a focused ethnography. Immigrants, refugees, asylum seekers and undocumented migrants were invited to participate. We collected data from November to December 2017 via semi-structured interviews and participant observation during group activities at La Maison Bleue. Data were thematically analysed. RESULTS: Twenty-four mothers participated (9 interviewed, 17 observed). Challenges to well-being included family separation, isolation, loss of support, the immigration process, an unfamiliar culture and environment, and language barriers. Key protective factors were women's intrinsic drive to overcome difficulties, their positive outlook and ability to find meaning in their adversity, their faith, culture and traditions, and supportive relationships, both locally and transnationally. La Maison Bleue strengthened resilience by providing a safe space, offering holistic care that responded to both medical and psychosocial needs, and empowering women to achieve their full potential towards better health for themselves and their families. CONCLUSION: Migrant mothers have many strengths and centres like La Maison Bleue can offer a safe space and be an empowering community resource to assist mothers in overcoming the multiple challenges that they face while resettling and raising their young children in a new country.


Assuntos
Empoderamento , Acessibilidade aos Serviços de Saúde , Centros de Saúde Materno-Infantil , Mães/psicologia , Resiliência Psicológica , Migrantes/psicologia , Adolescente , Adulto , Antropologia Cultural , Canadá/epidemiologia , Criança , Pré-Escolar , Barreiras de Comunicação , Redes Comunitárias/organização & administração , Redes Comunitárias/normas , Emigrantes e Imigrantes/psicologia , Emigrantes e Imigrantes/estatística & dados numéricos , Feminino , Humanos , Lactente , Recém-Nascido , Masculino , Centros de Saúde Materno-Infantil/organização & administração , Centros de Saúde Materno-Infantil/normas , Mães/estatística & dados numéricos , Gravidez , Quebeque/epidemiologia , Refugiados/psicologia , Refugiados/estatística & dados numéricos , Migrantes/estatística & dados numéricos
9.
Trop Doct ; 49(4): 298-300, 2019 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-31333059

RESUMO

Community mobilisation is an essential part of cervical cancer screening programmes to increase demand for screening services. While there are different methods of community mobilisation, in Ethiopia community conversations during traditional coffee ceremonies appear to be a context appropriate and effective method. Linkage of community mobilisation with existing community networks can increase uptake of cervical cancer screening and improve continuous support and care among community members.


Assuntos
Café , Serviços de Saúde Comunitária/métodos , Redes Comunitárias/organização & administração , Detecção Precoce de Câncer/métodos , Neoplasias do Colo do Útero/diagnóstico , Adulto , Serviços de Saúde Comunitária/organização & administração , Etiópia/epidemiologia , Feminino , Humanos , Pessoa de Meia-Idade , Neoplasias do Colo do Útero/epidemiologia , Neoplasias do Colo do Útero/prevenção & controle
10.
Am J Health Syst Pharm ; 76(15): 1150-1157, 2019 Jul 18.
Artigo em Inglês | MEDLINE | ID: mdl-31201774

RESUMO

PURPOSE: The development and dissemination of a specialty pharmacy service to optimize fingolimod therapy management are described. SUMMARY: Fingolimod was the first oral therapy developed to counter relapsing-remitting multiple sclerosis. Pharmacovigilance measures and individualized support are strongly recommended due to associated safety concerns. The Fingolimod Patient Support Program (F-PSP) was developed and disseminated within a community pharmacy network. The F-PSP aims to ensure responsible use of fingolimod and patient empowerment by promoting medication adherence and patient safety through a person-centered and integrated care approach. It complements basic pharmacy services through 2 interventions: medication adherence support and pharmacovigilance tailored to fingolimod. The adherence intervention combines motivational interviewing with longitudinal electronic medication adherence monitoring. The pharmacovigilance component consists of informing patients of fingolimod recommendations, reminding patients of recommended medical tests, and tracking and monitoring symptoms, especially those of potential serious adverse fingolimod reactions. A secure Web platform guides the pharmacist in conducting interviews and enables collection of patient-reported outcome data. A transition care pharmacist proposes program participation to all patients initiated on fingolimod, performs enrollment, and coordinates transfers to patient-designated community pharmacies for ongoing care. CONCLUSION: The F-PSP enables support of individual patients, and also provides real-world data, helping to bridge the gap between practice and research. The F-PSP is intended to be a generic model of a specialty pharmacy service that is transferable to any other healthcare context, specialty drug or disease.


Assuntos
Serviços Comunitários de Farmácia/organização & administração , Cloridrato de Fingolimode/uso terapêutico , Conduta do Tratamento Medicamentoso/organização & administração , Esclerose Múltipla Recidivante-Remitente/tratamento farmacológico , Transferência de Pacientes/organização & administração , Administração Oral , Redes Comunitárias/organização & administração , Prestação Integrada de Cuidados de Saúde/organização & administração , Feminino , Humanos , Adesão à Medicação/psicologia , Entrevista Motivacional , Educação de Pacientes como Assunto , Segurança do Paciente , Farmacêuticos/organização & administração , Farmacovigilância , Desenvolvimento de Programas , Suíça
11.
Int J Older People Nurs ; 14(3): e12248, 2019 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-31173482

RESUMO

AIMS AND OBJECTIVES: This study sought to assess the effect of a community-based intervention influencing adherence status at baseline, 1, 3 and 6 months, and to evaluate the impact that a community-based intervention and socio-economic factors have on adherence. BACKGROUND: Although high-quality treatment and modern hypertension clinical practice guidelines have been developed worldwide, the outcomes of patients with hypertension in Thailand are not optimal. Implementing a person-centred and integrated health services model to improve hypertension management, such as a community-based intervention, is challenging for healthcare providers in Thailand. DESIGN: An observational study of a community-based intervention. METHODS: The study comprised residents in 17 villages in one province of Thailand. A sample of 156 participants was allocated into the intervention and the control groups. Inclusion criteria were people aged 60 years or older diagnosed with hypertension. Exclusion criteria included the latest record of extreme hypertension and having a documented history of cognitive impairment. The intervention group received the 4-week community-based intervention programme. Multiple linear regression was applied to predict the adherence status at each phase. Multiple logistic regression was then implemented to predict influencing factors between the groups. RESULTS: Patients who received the intervention had significantly lower adherence scores (reflecting a higher level of adherence) at 3 and 6 months after intervention by 1.66 and 1.45 times, respectively, when adjusting for other variables. After 6 months, the intervention was associated with a significant improvement in adherence when adjusting for other variables. CONCLUSION: This study provides evidence to support the use of community-based interventions as an effective adjunct to hospital-based care of hypertension patients in Thailand. IMPLICATIONS FOR PRACTICE: Understanding factors between health outcomes and social determinants of health is crucial for informing the development of culturally appropriate interventions.


Assuntos
Redes Comunitárias/organização & administração , Hipertensão/enfermagem , Cooperação do Paciente , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Determinantes Sociais da Saúde , Fatores Socioeconômicos , Tailândia
15.
BMJ Support Palliat Care ; 9(4): e32, 2019 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-30389694

RESUMO

Palliative care is recognised as a fundamental component of Universal Health Coverage (UHC), which individual countries, led by the United Nations and the WHO, are committed to achieving worldwide by 2030-Sustainable Development Goal (SDG) 3.8. As the incidence of non-communicable diseases (NCD) in low-income and middle-income countries (LMICs) increases, their prevention and control are the central aspects of UHC in these areas. While the main focus is on reducing premature mortality from NCDs (SDG 3.4), palliative care is becoming increasingly important in LMICs, in which 80% of the need is found. This paper discusses the challenges of providing comprehensive NCD management in LMICs, the role of palliative care in addressing the huge and growing burden of serious health-related suffering, and also its scope for leveraging various aspects of primary care NCD management. Drawing on experiences in India and Nepal, and particularly a project on the India-Nepal border in which palliative care, community health and primary care-led NCD management are being integrated, we explore the synergies arising and describe a model where palliative care is integral to the whole spectrum of NCD management, from promotion and prevention, through treatment, rehabilitation and palliation. We believe this model could provide a framework for integrated NCD management more generally in rural India and Nepal and also other LMICs as they work to make NCD management as part of UHC a reality.


Assuntos
Redes Comunitárias/organização & administração , Prestação Integrada de Cuidados de Saúde/organização & administração , Doenças não Transmissíveis/terapia , Cuidados Paliativos/organização & administração , Atenção Primária à Saúde/organização & administração , Humanos , Índia , Nepal , Cuidados Paliativos/métodos , Pobreza , Atenção Primária à Saúde/métodos
16.
Clin Interv Aging ; 13: 2083-2095, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-30425463

RESUMO

Current trends in health care delivery and management such as predictive and personalized health care incorporating information and communication technologies, home-based care, health prevention and promotion through patients' empowerment, care coordination, community health networks and governance represent exciting possibilities to dramatically improve health care. However, as a whole, current health care trends involve a fragmented and scattered array of practices and uncoordinated pilot projects. The present paper describes an innovative and integrated model incorporating and "assembling" best practices and projects of new innovations into an overarching health care system that can effectively address the multidimensional health care challenges related to aging patient especially with chronic health issues. The main goal of the proposed model is to address the emerging health care challenges of an aging population and stimulate improved cost-efficiency, effectiveness, and patients' well-being. The proposed home-based and community-centered Integrated Healthcare Management System may facilitate reaching the persons in their natural context, improving early detection, and preventing illnesses. The system allows simplifying the health care institutional structures through interorganizational coordination, increasing inclusiveness and extensiveness of health care delivery. As a consequence of such coordination and integration, future merging efforts of current health care approaches may provide feasible solutions that result in improved cost-efficiency of health care services and simultaneously increase the quality of life, in particular, by switching the center of gravity of health delivery to a close relationship of individuals in their communities, making best use of their personal and social resources, especially effective in health delivery for aging persons with complex chronic illnesses.


Assuntos
Doença Crônica/terapia , Difusão de Inovações , Serviços de Saúde para Idosos/tendências , Dinâmica Populacional/tendências , Idoso , Áustria , Doença Crônica/economia , Doença Crônica/epidemiologia , Doença Crônica/prevenção & controle , Redes Comunitárias/economia , Redes Comunitárias/organização & administração , Redes Comunitárias/tendências , Análise Custo-Benefício/tendências , Prestação Integrada de Cuidados de Saúde/economia , Prestação Integrada de Cuidados de Saúde/organização & administração , Prestação Integrada de Cuidados de Saúde/tendências , Previsões , Necessidades e Demandas de Serviços de Saúde/economia , Necessidades e Demandas de Serviços de Saúde/organização & administração , Necessidades e Demandas de Serviços de Saúde/tendências , Serviços de Saúde para Idosos/economia , Serviços de Saúde para Idosos/organização & administração , Serviços de Assistência Domiciliar/economia , Serviços de Assistência Domiciliar/organização & administração , Serviços de Assistência Domiciliar/tendências , Humanos , Assistência Centrada no Paciente/economia , Assistência Centrada no Paciente/organização & administração , Assistência Centrada no Paciente/tendências , Projetos Piloto , Qualidade de Vida , Telemedicina/economia , Telemedicina/organização & administração , Telemedicina/tendências
17.
Cancer ; 124(21): 4231-4240, 2018 11 01.
Artigo em Inglês | MEDLINE | ID: mdl-30317547

RESUMO

BACKGROUND: The impact of National Comprehensive Cancer Network (NCCN) treatment guideline concordance on costs, health care utilization, and mortality for patients with breast cancer and secondary metastases is unknown. METHODS: From 2007 to 2013, women with early-stage breast cancer who received treatment for secondary metastases (n = 5651) were evaluated for first recorded systemic therapy concordance with NCCN guidelines within the Surveillance, Epidemiology, and End Results Program-Medicare linked database. Generalized linear and mixed effects models evaluated factors associated with nonconcordance and the relation between concordance status and health care utilization and costs. Mortality risk was estimated with Cox regression. RESULTS: Eighteen percent of the patients received nonconcordant therapy, with the most common being single-agent, human epidermal growth factor receptor 2 (HER2)-targeted therapy (36%), therapy mismatched with the estrogen receptor/HER2 status (11%), unapproved bevacizumab regimens (10%), and adjuvant regimens in a metastatic setting (6%). A younger age, a hormone receptor-negative status, and a HER2-positive status were associated with nonconcordance (P < .05). Nonconcordance was associated with 22% and 21% increased rates of emergency department visits and hospitalizations, respectively, and $1765 higher average monthly Medicare costs. Differences in adjusted mortality risk were noted by the category of nonconcordance; single-agent, HER2-targeted therapy was associated with decreased mortality risk (hazard ratio [HR], 0.66; 95% confidence limit [CL], 0.57-0.76), and increased mortality risk was observed with unapproved bevacizumab use (HR, 1.40; 95% CL, 1.13-1.74). CONCLUSIONS: Most patients (82%) received treatment consistent with NCCN guidelines. Nonconcordant treatment was associated with higher health care utilization and costs, with mortality differences observed by the type of guideline deviation. Consideration of both patient and financial outcomes will be important as health systems increase the emphasis on guideline-based care.


Assuntos
Neoplasias da Mama/economia , Neoplasias da Mama/mortalidade , Neoplasias da Mama/terapia , Fidelidade a Diretrizes/estatística & dados numéricos , Custos de Cuidados de Saúde/estatística & dados numéricos , Oncologia/normas , Aceitação pelo Paciente de Cuidados de Saúde/estatística & dados numéricos , Idoso , Idoso de 80 Anos ou mais , Neoplasias da Mama/patologia , Redes Comunitárias/organização & administração , Redes Comunitárias/normas , Assistência Integral à Saúde/organização & administração , Assistência Integral à Saúde/normas , Feminino , Fidelidade a Diretrizes/economia , Humanos , Revisão da Utilização de Seguros , Medicare/estatística & dados numéricos , Pessoa de Meia-Idade , Metástase Neoplásica , Guias de Prática Clínica como Assunto , Programa de SEER , Sociedades Médicas/normas , Estados Unidos/epidemiologia
18.
BMJ Open ; 8(7): e022028, 2018 07 19.
Artigo em Inglês | MEDLINE | ID: mdl-30030320

RESUMO

INTRODUCTION: Improving complementary feeding in Ethiopia requires special focus on dietary diversity. The Sustainable Undernutrition Reduction in Ethiopia (SURE) programme is a government-led multisectoral intervention that aims to integrate the work of the health and agriculture sectors to deliver a complex multicomponent intervention to improve child feeding and reduce stunting. The Federal Ministries of Health and Agriculture and Natural Resources implement the intervention. The evaluation aims to assess a range of processes, outcomes and impacts. METHODS AND ANALYSIS: The SURE evaluation study is a theory-based, mixed methods study comprising impact and process evaluations. We hypothesise that the package of SURE interventions, including integrated health and agriculture behaviour change communication for nutrition, systems strengthening and multisectoral coordination, will result in detectable differences in minimum acceptable diet in children 6-23 months and stunting in children 24-47 months between intervention and comparison groups. Repeated cross-sectional household surveys will be conducted at baseline and endline to assess impact. The process will be assessed using observations, key informant interviews and focus group discussions to investigate the fidelity and dose of programme implementation, behavioural pathways of impact and contextual factors interacting with the intervention. Pathways of impact will also be explored through statistical analyses. ETHICS AND DISSEMINATION: The study has received ethics approval from the scientific and ethical review committees at the Ethiopian Public Health Institute and the London School of Hygiene and Tropical Medicine. The findings will be disseminated collaboratively with stakeholders at specified time points and through peer-reviewed publications and presentations.


Assuntos
Agricultura/organização & administração , Redes Comunitárias/organização & administração , Transtornos do Crescimento/prevenção & controle , Fenômenos Fisiológicos da Nutrição do Lactente , Desnutrição/prevenção & controle , Avaliação de Programas e Projetos de Saúde/métodos , Fenômenos Fisiológicos da Nutrição Infantil , Pré-Escolar , Ensaios Clínicos como Assunto , Estudos Transversais , Etiópia/epidemiologia , Estudos de Avaliação como Assunto , Comportamento Alimentar , Feminino , Grupos Focais , Abastecimento de Alimentos , Transtornos do Crescimento/epidemiologia , Transtornos do Crescimento/etiologia , Educação em Saúde , Humanos , Lactente , Masculino , Desnutrição/complicações , Desnutrição/epidemiologia , Estado Nutricional , Desenvolvimento de Programas
19.
Cancer ; 124(17): 3510-3519, 2018 09 01.
Artigo em Inglês | MEDLINE | ID: mdl-29984547

RESUMO

BACKGROUND: The incidence of rectal cancer in patients younger than 50 years is increasing. To test the hypothesis that the biology in this younger cohort may differ, this study compared survival patterns, stratifying patients according to National Comprehensive Cancer Network (NCCN) guideline-driven care and age. METHODS: The National Cancer Data Base was queried for patients treated with curative-intent transabdominal resections with negative surgical margins for stage I to III rectal cancer between 2004 and 2014. Outcomes and overall survival for patients younger than 50 years and patients 50 years old or older were compared by subgroups based on NCCN guideline-driven care. RESULTS: A total of 43,106 patients were analyzed. Younger patients were more likely to be female and minorities, to be diagnosed at a higher stage, and to have travelled further to be treated at academic/integrated centers. Short- and long-term outcomes were significantly better for patients younger than 50 years, with age-specific survival rates calculated. Younger patients were more likely to receive radiation treatment outside NCCN guidelines for stage I disease. In younger patients, the administration of neoadjuvant chemoradiation for stage II and III disease was not associated with an overall survival benefit. CONCLUSIONS: Age-specific survival data for patients with rectal cancer treated with curative intent do not support an overall survival benefit from NCCN guideline-driven therapy for stage II and III patients younger than 50 years. These data suggest that early-onset disease may differ biologically and in its response to multimodality therapy.


Assuntos
Oncologia/normas , Guias de Prática Clínica como Assunto , Neoplasias Retais/mortalidade , Neoplasias Retais/terapia , Adulto , Fatores Etários , Idade de Início , Idoso , Estudos de Coortes , Redes Comunitárias/organização & administração , Redes Comunitárias/normas , Intervalo Livre de Doença , Feminino , Humanos , Masculino , Oncologia/organização & administração , Pessoa de Meia-Idade , Estadiamento de Neoplasias , Neoplasias Retais/diagnóstico , Neoplasias Retais/patologia , Estudos Retrospectivos , Medição de Risco , Sociedades Médicas/organização & administração , Sociedades Médicas/normas , Taxa de Sobrevida , Resultado do Tratamento , Estados Unidos/epidemiologia , Adulto Jovem
20.
Riv Psichiatr ; 53(3): 149-153, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-29912217

RESUMO

Background: Clinical practice of mental health services changed in 1978 after the Basaglia Law was passed, and it is now characterized by usually voluntary treatments offered by community-based services. That broadened the interventions' focus from the single subject to their environment. Dual diagnosis is defined by WHO as «the co-occurrence in the same individual of a psychoactive substance use disorder and another psychiatric disorder¼. It is considered to be a "border territory" since entails networking between different medical services. Materials and methods: A literature search was performed in PubMed, Web of Science, Scopus and Google Scholar. Search terms were: "guidelines", "treatment", "comorbidity", "substance abuse", "alcohol", "dual-diagnosis", "psychiatric illness", "outpatient", "inpatient", "health care service", "clinical practice". National and regional regulations about health and addiction were screened too. Out of 598 titles, 31 studies were included in this article for their relevance on treatments and networking between services for dual diagnosis cases. Results: There are not any guidelines for clinical practice in the literature, neither there are any shared treatment strategies on a national level. Considering the autonomy that every regional health service has, several different courses of action are possible. Here there are reported the ones available. Conclusions: After discussing the weak points of the treatment options, we suggest the "Multidisciplinary Healthcare" model to best address the difficulties represented by dual diagnosis cases.


Assuntos
Alcoolismo/terapia , Diagnóstico Duplo (Psiquiatria) , Transtornos Mentais/terapia , Alcoolismo/reabilitação , Serviços Comunitários de Saúde Mental/organização & administração , Redes Comunitárias/organização & administração , Desinstitucionalização/legislação & jurisprudência , Gerenciamento Clínico , Mão de Obra em Saúde/legislação & jurisprudência , Humanos , Comunicação Interdisciplinar , Itália , Transtornos Mentais/reabilitação , Programas Nacionais de Saúde/organização & administração , Equipe de Assistência ao Paciente , Guias de Prática Clínica como Assunto , Centros de Reabilitação/organização & administração , Comunidade Terapêutica
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA