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1.
Ann Plast Surg ; 89(1): 59-62, 2022 07 01.
Artigo em Inglês | MEDLINE | ID: mdl-35502975

RESUMO

OBJECTIVE: Tai Chi is an ancient philosophy used to explain the universe. The Tai Chi symbol is represented by Yin/Yang fishes. The authors describe a novel radial forearm flap (RFF) design for the reconstruction of circular defects based on the Tai Chi symbol. METHODS: Eleven consecutive patients with craniofacial skin or mucus defects underwent reconstruction with a Tai Chi RFF. Patient perioperative and follow-up information was collected. RESULTS: The diameter of the Tai Chi RFF was 5 to 6 cm. All flaps healed uneventfully without ischemic problems, and all donor site defects were closed primarily without skin grafts. Remarkably, 2 patients received a tattoo to mark the Tai Chi symbol and greatly appreciate the shape of the flap. CONCLUSIONS: The Tai Chi flap is an economically friendly flap design that can be used to prevent skin grafts while providing psychological comfort to patients.


Assuntos
Procedimentos de Cirurgia Plástica , Tai Chi Chuan , Antebraço/cirurgia , Humanos , Transplante de Pele , Retalhos Cirúrgicos/cirurgia
3.
Int J Colorectal Dis ; 34(9): 1619-1623, 2019 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-31378835

RESUMO

PURPOSE: A rectovaginal fistula (RVF) is a rare disease. It's an epithelium-lined abnormal communication between rectum and vagina. It represents approximately 5% of all anorectal fistulas. RVF may have different causes. METHODS: We present a case of a 58-year-old woman with a rectovaginal fistula after stapled hemorrhoidopexy (Longo operation). RESULTS: A 58-year-old woman presented herself in our department with vaginal fecal discharge and vaginitis almost one month after a stapled hemorrhoidopexy was performed in another hospital. On vaginal examination, a large dorsal defect was palpated at four cm. On rectal examination, the stapler line was palpable at four cm and just distal to this stapler line, a large defect could be palpated. A lower gastrointestinal tract radiography was performed and identified a RVF. The patient was put on antibiotics and two operations were planned. First, a temporary ileostomy was created. After healing of the vaginitis, reconstructive surgery with anatomic fistula repair in combination with the interposition of healthy, vascularised tissue was performed. In this case, we chose the Martius flap. The operation as well as the postoperative course was uneventful. CONCLUSIONS: Cases of postoperative RVF have been increasingly reported since the introduction of stapled hemorrhoidopexy. Patients with RVF can have a varying degree of symptoms. Diagnosis is primarily based on the patient's medical history together with a clinical examination. There are many surgical approaches for RVF. Anatomic fistula repair alone is associated with lower success rates compared with combined procedures with the adjunctive interposition of healthy, vascularised tissue.


Assuntos
Hemorroidas/cirurgia , Procedimentos de Cirurgia Plástica , Fístula Retovaginal/cirurgia , Retalhos Cirúrgicos/cirurgia , Grampeamento Cirúrgico , Bário , Enema , Feminino , Humanos , Pessoa de Meia-Idade , Fístula Retovaginal/diagnóstico por imagem
4.
Rev. argent. cir. plást ; 25(2): 77-79, apr-jun.2019. fig
Artigo em Espanhol | LILACS, BINACIS | ID: biblio-1152235

RESUMO

Entre los tumores malignos de la pared torácica, los sarcomas representan menos del 1% de los casos. A pesar de ser infrecuentes, es importante resaltar el manejo multidisciplinario de estos tipos de tumores ya que se caracterizan por ser de gran tamaño y afectar una amplia superficie torácica y por consiguiente de los tejidos blandos anexos a los mismos. De ahí la real importancia de la participación de cirujanos plásticos, torácicos y oncólogos en el tratamiento de estos tumores. La confección del colgajo dorsal en cirugías de sarcomas de la pared torácica ha permitido completar el tratamiento resectivo de dichos tumores. Presentamos el caso de un paciente varón de 64 años, con un sarcoma de la parrilla costal, quien fue sometido a resección amplia de la lesión que comprometia a la 7ma, 8va y 9na costillas, reconstrucción inmediata con próstesis de titanio y malla de polipropileno y cobertura del defecto con confección de colgajo del dorsal ancho. A 5 meses de seguimiento, sin evidencia de actividad de la enfermedad


Among malignant tumors of the chest wall, sarcomas account for less than 1% of cases. Despite being infrequent, it is important to highlight the multidisciplinary management of these types of tumors since they are characterized by being large and affecting a wide chest area and therefore the soft tissues attached to them. Hence the real importance of the participation of pásticos, thoracic and oncologos surgeons in the treatment of these tumors.The confection of the dorsal flap in surgeries of sarcomas of the thoracic wall has allowed to complete the treatment of these tumors. We present the case of a 64-year-old male patient with a sarcoma of the rib cage, who underwent extensive resection of the lesion involving the 7th, 8th and 9th ribs, immediate reconstruction with titanium prosthesis and mesh. polypropylene and coverage of the defect with flap made of the latissimus dorsi. At 5 months of follow-up, without evidence of disease activity.


Assuntos
Humanos , Masculino , Pessoa de Meia-Idade , Próteses e Implantes , Retalhos Cirúrgicos/cirurgia , Telas Cirúrgicas , Procedimentos de Cirurgia Plástica , Parede Torácica/cirurgia , Comunicação Interdisciplinar , Terapia de Tecidos Moles
5.
J Investig Clin Dent ; 10(1): e12368, 2019 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-30353707

RESUMO

The aim of the present study was to assess the efficacy of low-intensity laser therapy (LILT) for harvesting palatal connective tissue graft (PCTG) in the treatment of gingival recession. Databases were searched up to May 2018. The addressed focused question was: Is adjunctive LILT effective in the healing of donor palatine area after harvesting PCTG? Screening of the initially identified studies resulted in four clinical studies. All studies showed that LILT was effective in improving clinical outcomes, such as tissue thickness, postoperative discomfort, remaining wound area, and visual analog score at follow up. Upon comparison with the control group, two studies showed significantly greater improvements in the clinical parameters and patient-centered outcomes for LILT than control groups at follow up. Due to the low number of included clinical studies, it remains debatable whether LILT improves clinical and patient-centered outcomes of PCTG procedures. Further randomized controlled trials are needed to evaluate the outcomes of LILT on the healing of donor palatine area after harvesting PCTG.


Assuntos
Retração Gengival/cirurgia , Retração Gengival/terapia , Terapia com Luz de Baixa Intensidade/métodos , Palato/cirurgia , Transplante de Tecidos/métodos , Tecido Conjuntivo/transplante , Bases de Dados Factuais , Gengiva/transplante , Humanos , Retalhos Cirúrgicos/cirurgia , Resultado do Tratamento , Cicatrização
7.
Cir. plást. ibero-latinoam ; 43(supl.1): s77-s86, sept. 2017. ilus, tab
Artigo em Espanhol | IBECS | ID: ibc-169061

RESUMO

Introducción y Objetivo. Los sarcomas de la extremidad superior suponen un bajo porcentaje dentro de los sarcomas en general. Las características anatómicas de las extremidades superiores representan un reto quirúrgico a la hora de conjugar la radicalidad con la preservación funcional de la extremidad. Por el contrario, la raíz de la extremidad ya presenta otras características anatómicas y dimensiones, permitiendo extirpaciones más amplias y siendo además asiento favorito de sarcomas de bajo grado. Con estas premisas, es de suponer que el pronóstico global de esta localización sea más favorable que el del resto de la extremidad. El objetivo del presente estudio es confirmar dicha hipótesis en base a nuestra propia experiencia. Material y Método. De los 131 sarcomas intervenidos en nuestro Servicio durante los últimos 10 años, recogemos 29 casos de sarcomas en extremidad superior, que dividimos en 2 grupos según su asiento: los que afectan a la cintura escapular (hombro, escápula y clavícula), con 12 casos; y los de asiento en la extremidad propiamente dicha (axila, brazo, antebrazo y mano) con 17 casos. Analizamos una serie de variables en ambos grupos: sexo, edad, localización, tipo histológico, grado de diferenciación, presentación, tipo de extirpación, tratamiento quirúrgico, terapias complementarias, estado local, estado general y seguimiento. Resultados. Los sarcomas de la cintura escapular fueron, en nuestro grupo de estudio, de menor grado que los de la extremidad propiamente dicha. Se presentaron en su mayoría como casos primarios. Estos sarcomas son susceptibles de tratamientos más radicales y como consecuencia, los márgenes obtenidos fueron mejores que los del otro grupo. Ninguno de los 12 pacientes con sarcoma en cintura escapular presentó enfermedad local o general. Los sarcomas de la extremidad superior propiamente dicha fueron de predomino femenino, de más alto grado y se presentaron como recidivas o persistencias en más de la mitad de los casos. Las posibilidades quirúrgicas locorregionales son menores. Se practicaron 3 amputaciones y 1 desarticulación. Se emplearon colgajos libres en 5 pacientes, 2 de ellos con componente óseo. El 47% de los pacientes recibió alguna forma de radioterapia y 2 pacientes recibieron quimioterapia. Contabilizamos 4 pacientes fallecidos, lo que supone un 24% del total de los casos de nuestro grupo. Conclusiones. Las características en nuestra serie de sarcomas de la raíz de la extremidad y de la extremidad propiamente dicha son distintas. En la primera las presentaciones primarias fueron más frecuentes, los grados de desdiferenciación más bajos y las extirpaciones más amplias, lo que se traduce en menor enfermedad local, general y mortalidad. Por el contrario, las presentaciones iniciales de los sarcomas de la extremidad (brazo, antebrazo y mano) fueron con frecuencia tras resecciones no planeadas, lo que se traduce en persistencias o recurrencias. Además, el grado de desdiferenciación de los sarcomas en esta zona es más alto y las extirpaciones que se consiguen no son tan amplias, por lo que los resultados en cuanto a enfermedad local, general o muerte por la enfermedad son peores (AU)


Background and Objective. Upper extremity sarcomas represent just a small percentage of all sarcomas. The anatomic characteristics of upper extremity challenge the goal of combining radicality and limb functional preservation. On the other hand, the limb root presents other features regarding dimensions and anatomy thus allowing wider resections. Moreover it is a common place for low grade sarcomas. With such premises it can be considered that the prognosis of sarcomas of this location is more favorable than those of the rest of the extremity. The aim of this study is to confirm this hypothesis, based on our own experience. Methods. During the last 10 years 131 sarcomas were operated in our Unit, 29 of them affecting the upper extremity were recruited. They were further subdivided into 2 groups according to their location: shoulder girdle (shoulder, scapula and clavicle) with 12 cases, and those arising at the limb itself (axilla, arm, forearm and hand) with 17 cases. Several variables were analyzed in both groups: gender, age, location, hystologic type, differentiation grade, presentation, extirpation regarding margins, surgical treatment, complementary therapies, local status, general status and follow - up. Results. Sarcomas of the shoulder girdle own lower grade than those of the extremity itself. They present mostly as primary cases.Wide resections were feasible and therefore the obtained margins were better than those of the other group. None of the 12 patients of this group has had neither local or general disease. Sarcomas of the extremity itself appeared more in women, with higher grades and they are seen firstly at our institution after inadequate surgical margins or as recurrences in more than half of the cases. Locoregional flap options are scarce. Three amputations and 1 shoulder disarticulation were done in this group. Five free flaps, 2 of them with osseous component, were used. Forty-seven patients received some kind of radiotherapy and 2 more patients received chemotherapy. Four deads were recorded among this group representing 24% of all cases. Conclusions. In our series the characteristics of sarcoma to the shoulder girdle and those of the extremity itself were different. In the former primary presentations as new cases are more frequent, dedifferentiation grades were lower and resections wider resulting in lower rates of local recurrences, general disease or mortality. On the other hand, sarcomas to the extremity appear mainly after unplanned resections as recurrences or inadequate margins excisions. Dedifferentiation grades here are higher and resections are not as wide as in the other group. Worse results regarding local disease, general disease or mortality were here recorded (AU)


Assuntos
Humanos , Sarcoma/cirurgia , Extremidade Superior/patologia , Sarcoma de Células Claras/cirurgia , Prognóstico , Retalhos Cirúrgicos/cirurgia , Lipossarcoma/cirurgia , Anamnese , Braquiterapia/métodos , Braço/patologia , Braço/cirurgia , Antebraço/patologia , Antebraço/cirurgia
9.
Ann Chir Plast Esthet ; 62(2): e1-e13, 2017 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-27427444

RESUMO

INTRODUCTION: Medicinal leeches have been part of the therapeutic armamenterium of plastic surgeons for more than 50 years. While their use in hand surgery is a matter of course, their use in salvage of flaps with venous congestion remains facultative depending on teams. MATERIALS AND METHODS: We conducted a systematic review of leech therapy for flap salvage between 1960 and 2015, analyzing 121 articles and subsequently taking into consideration 41 studies. In parallel, we collected data from 43 patients for whom leach therapy had recently been applied in treatment of venous insufficiency in pedicled or free flaps after revision surgery had failed to improve flap vascularization, or in cases where flap revision was not appropriate. The data collected pertained to relevant indications, treatment procedure, efficacy, adjuvant therapies, side effects and complications. RESULTS: For this indication, the success rate of leech therapy ranged from 65 to 85% (83.7% in our series) according to the situations encountered. Optimal frequency of application ranged from 2 to 8hours, while average overall duration ranged from 4 to 10 days. The number of leeches to be applied can be determined depending on volume of the flap. In 50% of the cases reported in the literature, the patients required transfusion. Antibiotic prophylaxis against Aeromonas is highly advisable. A ciprofloxacin and trimethoprim-sulfametoxazole combination currently appears as the most relevant prophylactic antibiotherapy. CONCLUSION: Hirudotherapy is a reliable treatment in cases of patent venous insufficiency of pedicled or free flaps (or when revision surgery is not recommended). Even though the relevant literature is highly heterogeneous, we have attempted to put forward a specific protocol bringing together dosage, delivery route, frequency of administration and appropriate prophylactic antibiotherapy. An algorithm for treatment and management of venous congestion and a practical information sheet have been placed at the disposal of plastic surgery teams.


Assuntos
Hiperemia/terapia , Aplicação de Sanguessugas/métodos , Terapia de Salvação/métodos , Retalhos Cirúrgicos/cirurgia , Aeromonas , Algoritmos , Antibioticoprofilaxia , Humanos
10.
Acta otorrinolaringol. esp ; 67(6): 339-344, nov.-dic. 2016. tab
Artigo em Inglês | IBECS | ID: ibc-157920

RESUMO

Introduction and objective: The most common postoperative complications of velopharyngeal insufficiency surgery are postoperative bleeding and airway obstruction or obstructive sleep apnoea. Consequently, the aim of this study was to evaluate the effect of low level laser therapy (LLLT) during the first postoperative days in children undergoing superiorly based pharyngeal flap (SBF) surgery. Materials and methods: A randomized double blind clinical study on 30 children divided on two groups 15 patients each, who underwent SBF. LLLT was used in a group and the other was a control group. The study was conducted in academic tertiary care medical centres between 2013 and 2015. The degree of edema, oxygen saturation, occurrence of obstructive sleep apnoea (OSA) and steroid administration were recorded. Results: The mean of the average oxygen saturation was significantly less in the control group in the 1st and 2nd day as compared to the laser group. The need for oxygen and the incidence of OSA in the first 3 days were significantly higher in the control group as compared to the laser group. The degree of edema showed no significant difference in the first day but was significantly higher in the control group in the 2nd and 3rd days. Hence, the need of steroids was significantly higher in the control group in the first 3 days. Conclusions: Preliminary results showed that low level laser therapy is effective in reducing the incidence of early postoperative airway obstruction after SBF operations (AU)


Introducción y objetivo: La más común de las complicaciones postoperatorias tras la cirugía de la insuficiencia velofaríngea son el sangrado y la obstrucción postoperatoria de las vías respiratorias, o la apnea obstructiva del sueño. Por lo tanto, el objetivo de este estudio fue evaluar el efecto de la terapia láser de baja intensidad durante los primeros días del postoperatorio en niños sometidos a colgajo faríngeo de base superior (SBF). Métodos: Estudio clínico aleatorizado doble ciego en 30 niños, entre el grupo de láser y el grupo control, que fueron sometidos a SBF. El estudio se llevó a cabo en dos centros médicos académicos de atención terciaria, entre 2013 y 2015. Se registró grado de edema, la saturación de oxígeno, la aparición de apnea obstructiva del sueño y la necesidad de esteroides. Resultados: Durante los 3 primeros días, la media de la saturación de oxígeno muestra cambios significativos entre los dos grupos. Por otra parte, la necesidad de oxígeno en los primeros 3 días muestra también cambios significativos entre los dos grupos. Así como la incidencia de apnea obstructiva del sueño. El grado de edema no muestra ningún cambio significativo en el primer día, pero sí en los 2 días siguientes. Por lo tanto, la necesidad de esteroides en los primeros 3 días también muestra cambios significativos entre los dos grupos. Conclusiones: Los resultados preliminares mostraron que la terapia con láser de baja intensidad es eficaz en la reducción de la incidencia de obstrucción de vía aérea en el postoperatorio temprano después de las operaciones SBF (AU)


Assuntos
Humanos , Masculino , Feminino , Criança , Terapia com Luz de Baixa Intensidade/métodos , Terapia com Luz de Baixa Intensidade , Retalhos Cirúrgicos/cirurgia , Insuficiência Velofaríngea/cirurgia , Insuficiência Velofaríngea/patologia , Cuidados Pós-Operatórios/métodos , Apneia Obstrutiva do Sono/congênito , Apneia Obstrutiva do Sono/patologia , Complicações Pós-Operatórias
11.
J Dent Res ; 95(5): 523-30, 2016 May.
Artigo em Inglês | MEDLINE | ID: mdl-26908630

RESUMO

Biological mediators have been used to enhance periodontal regeneration. The aim of this prospective randomized controlled study was to evaluate the safety and effectiveness of 3 doses of fibroblast growth factor 2 (FGF-2) when combined with a ß-tricalcium phosphate (ß-TCP) scaffold carrier placed in vertical infrabony periodontal defects in adult patients. In this double-blinded, dose-verification, externally monitored clinical study, 88 patients who required surgical intervention to treat a qualifying infrabony periodontal defect were randomized to 1 of 4 treatment groups-ß-TCP alone (control) and 0.1% recombinant human FGF-2 (rh-FGF-2), 0.3% rh-FGF-2, and 0.4% rh-FGF-2 with ß-TCP-following scaling and root planing of the tooth prior to a surgical appointment. Flap surgery was performed with EDTA conditioning of the root prior to device implantation. There were no statistically significant differences in patient demographics and baseline characteristics among the 4 treatment groups. When a composite outcome of gain in clinical attachment of 1.5 mm was used with a linear bone growth of 2.5 mm, a dose response pattern detected a plateau in the 0.3% and 0.4% rh-FGF-2/ß-TCP groups with significant improvements over control and 0.1% rh-FGF-2/ß-TCP groups. The success rate at 6 mo was 71% in the 2 higher-concentration groups, as compared with 45% in the control and lowest treatment groups. Percentage bone fill in the 2 higher-concentration groups was 75% and 71%, compared with 63% and 61% in the control and lowest treatment group. No increases in specific antibody to rh-FGF-2 were detected, and no serious adverse events related to the products were reported. The results from this multicenter trial demonstrated that the treatment of infrabony vertical periodontal defects can be enhanced with the addition of rh-FGF-2/ß-TCP (ClinicalTrials.gov NCT01728844).


Assuntos
Perda do Osso Alveolar/cirurgia , Substitutos Ósseos/uso terapêutico , Fosfatos de Cálcio/uso terapêutico , Fator 2 de Crescimento de Fibroblastos/uso terapêutico , Adulto , Idoso , Perda do Osso Alveolar/tratamento farmacológico , Raspagem Dentária/métodos , Relação Dose-Resposta a Droga , Método Duplo-Cego , Feminino , Fator 2 de Crescimento de Fibroblastos/administração & dosagem , Seguimentos , Regeneração Tecidual Guiada Periodontal/métodos , Humanos , Masculino , Pessoa de Meia-Idade , Osteogênese/efeitos dos fármacos , Osteogênese/fisiologia , Perda da Inserção Periodontal/tratamento farmacológico , Perda da Inserção Periodontal/cirurgia , Estudos Prospectivos , Proteínas Recombinantes , Aplainamento Radicular/métodos , Segurança , Retalhos Cirúrgicos/cirurgia , Alicerces Teciduais , Resultado do Tratamento
12.
Zhonghua Zheng Xing Wai Ke Za Zhi ; 32(5): 354-8, 2016 Sep.
Artigo em Chinês | MEDLINE | ID: mdl-30066993

RESUMO

Objective: To devAop a new approach for functional penile reconstruction. Methods: Total penile reconstruction using innervated gracilis muscles and anterolateral thigh (ALT) flap with fascia lata was performed on four human cadavers. Canine models were constructed using gracilis muscles and lower abdominal flap with anterior rectus sheaih, instead of the ALT flap. Seven months later, the erectile function of the neophalli elicited by electrostimulation was evaluated. The length, diameter and stiffness were measured respectively and the results were analyzed statistically using paired-samples t test. Results: The penile reconstruction was success with good appearance in the cadaveric study. The hardness of the reconstructed penis in canine models was graded as 1.2 ± 0.4 at rest. With the nerve pedicles stimulated, it increased significantly and was graded as 3.4 ± 0.5 (P < 0.05),while the length shortened and the diameter did not change significantly. A successful erection-mimic course was observed. Conclusions: It indicates that penile reconstruction with skin flaps combined with muscle is feasible, serving as a theoretical and technical support for further clinical application.


Assuntos
Procedimentos de Cirurgia Plástica/métodos , Transplante de Pele , Retalhos Cirúrgicos/cirurgia , Animais , Cães , Fascia Lata , Humanos , Masculino , Ereção Peniana , Pênis/cirurgia , Coxa da Perna/cirurgia
13.
J Periodontal Res ; 51(2): 175-85, 2016 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-26095265

RESUMO

BACKGROUND AND OBJECTIVE: Many techniques and flap designs have been used to treat gingival recession by root coverage, but subepithelial connective tissue graft (SCTG) seems to be the gold standard procedure. In an attempt to improve the healing process and increase the success rate of root coverage, some authors have used root modifiers, including different root conditioners, lasers, EMD, recombinant human growth factors and platelet-rich plasma (PRP). The aim of this systematic review was to evaluate the effects of root biomodification in clinical outcomes of gingival recessions treated with SCTG. MATERIAL AND METHODS: Studies reporting SCTG associated with any form of root surface biomodification for root coverage of gingival recessions (Miller Class I and Class II) were considered as eligible for inclusion. Studies needed to have data of clinical outcomes in a follow up of at least 6 months. Screening of the articles, data extraction and quality assessment were conducted independently and in duplicate. RESULTS: None of the products evaluated (citric acid, EDTA, PRP, lasers and EMD) showed evident benefits in clinical outcomes. Test and control groups presented similar outcomes related to root coverage and periodontal parameters, with no statistical differences between them. The exception was root biomodification with the neodymium-doped yttrium aluminium garnet (Nd:YAG) laser, which impaired root coverage and had a detrimental effect on clinical outcomes. CONCLUSION: Based on the present clinical data, the use of root surface modifiers to improve clinical outcomes in gingival recessions treated with SCTG is not justified. More in vivo studies, and randomized clinical trials with larger sample sizes and extended follow up, are necessary.


Assuntos
Retração Gengival , Tecido Conjuntivo , Seguimentos , Gengiva , Retração Gengival/cirurgia , Humanos , Retalhos Cirúrgicos/cirurgia , Raiz Dentária/cirurgia , Resultado do Tratamento
14.
J Clin Periodontol ; 42(3): 288-93, 2015 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-25640329

RESUMO

AIM: This study evaluated the effects of a topical herbal patch (PerioPatch®) for gingival wound healing in a rat model. MATERIALS AND METHODS: A mid-crestal incision was performed on each side of the edentulous anterior maxilla in 48, 6-month-old, Wistar rats. Full-thickness flaps were raised, repositioned and sutured. Four experimental groups were established: herbal patch, placebo patch, no patch and no patch and no surgery. Patches were placed immediately after surgery and replaced every 12 h for the following 3 days. Half of the animals were killed after 5 and the remaining ones after 12 days. Tissue blocks were retrieved and processed for histological and immunohistochemical evaluation. Epithelial gap, collagen contents, amount of macrophages, cellular proliferation and vascular contents were evaluated in the central incision area. Statistical analysis consisted of two-way anova. RESULTS: The herbal patch group presented the smallest epithelial gap at 12 days, the highest collagen content both at 5 and 12 days, a larger number of proliferating cells at day 5 and more numerous blood vessels at day 12. Macrophage number was similar in all groups. CONCLUSION: Herbal patch improved wound healing in this animal model.


Assuntos
Gengiva/cirurgia , Fitoterapia/métodos , Extratos Vegetais/uso terapêutico , Animais , Contagem de Células , Proliferação de Células/efeitos dos fármacos , Centella , Colágeno/análise , Avaliação Pré-Clínica de Medicamentos , Echinacea , Epitélio/efeitos dos fármacos , Epitélio/patologia , Gengiva/efeitos dos fármacos , Gengiva/patologia , Arcada Edêntula/cirurgia , Macrófagos/efeitos dos fármacos , Macrófagos/patologia , Maxila/cirurgia , Microvasos/efeitos dos fármacos , Microvasos/patologia , Modelos Animais , Placebos , Ratos , Ratos Wistar , Reepitelização/efeitos dos fármacos , Sambucus nigra , Retalhos Cirúrgicos/patologia , Retalhos Cirúrgicos/cirurgia , Fatores de Tempo , Triterpenos/uso terapêutico , Cicatrização/efeitos dos fármacos
15.
J Periodontol ; 86(3): 367-75, 2015 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-25415250

RESUMO

BACKGROUND: The specific advantage of administering systemic antibiotics during initial, non-surgical therapy or in the context of periodontal surgery is unclear. This study assesses the differential outcomes of periodontal therapy supplemented with amoxicillin-metronidazole during either the non-surgical or the surgical treatment phase. METHODS: This is a single-center, randomized placebo-controlled crossover clinical trial with a 1-year follow-up. Eighty participants with Aggregatibacter actinomycetemcomitans-associated moderate to advanced periodontitis were randomized into two treatment groups: group A, antibiotics (500 mg metronidazole plus 375 mg amoxicillin three times per day for 7 days) during the first, non-surgical phase of periodontal therapy (T1) and placebo during the second, surgical phase (T2); and group B, placebo during T1 and antibiotics during T2. The number of sites with probing depth (PD) >4 mm and bleeding on probing (BOP) per patient was the primary outcome. RESULTS: A total of 11,212 sites were clinically monitored on 1,870 teeth. T1 with antibiotics decreased the number of sites with PD >4 mm and BOP per patient significantly more than without (group A: from 34.5 to 5.7, 84%; group B: from 28.7 to 8.7, 70%; P <0.01). Twenty patients treated with antibiotics, but only eight treated with placebo, achieved a 10-fold reduction of diseased sites (P = 0.007). Consequently, fewer patients of group A needed additional therapy, the mean number of surgical interventions was lower, and treatment time in T2 was shorter. Six months after T2, the mean number of residual pockets (group A: 2.8 ± 5.2; group B: 2.2 ± 5.0) was not significantly different and was sustained over 12 months in both groups. CONCLUSION: Giving the antibiotics during T1 or T2 yielded similar long-term outcomes, but antibiotics in T1 resolved the disease quicker and thus reduced the need for additional surgical intervention.


Assuntos
Amoxicilina/uso terapêutico , Antibacterianos/uso terapêutico , Metronidazol/uso terapêutico , Periodontite/terapia , Adulto , Idoso , Aggregatibacter actinomycetemcomitans/efeitos dos fármacos , Amoxicilina/administração & dosagem , Antibacterianos/administração & dosagem , Terapia Combinada , Estudos Cross-Over , Método Duplo-Cego , Combinação de Medicamentos , Feminino , Seguimentos , Humanos , Masculino , Metronidazol/administração & dosagem , Pessoa de Meia-Idade , Infecções por Pasteurellaceae/cirurgia , Infecções por Pasteurellaceae/terapia , Desbridamento Periodontal/métodos , Índice Periodontal , Bolsa Periodontal/cirurgia , Bolsa Periodontal/terapia , Periodontite/microbiologia , Periodontite/cirurgia , Placebos , Retalhos Cirúrgicos/cirurgia , Resultado do Tratamento
16.
Rev. bras. cir. plást ; 30(2): 163-171, 2015. ilus, tab
Artigo em Inglês, Português | LILACS | ID: biblio-996

RESUMO

Introdução: O primeiro tratamento eficaz para o câncer de mama foi descrito em 1894. A partir das décadas de 60 e 70, cirurgias menos agressivas foram desenvolvidas, sem prejuízos oncológicos. Com evolução histórica semelhante, o retalho do músculo grande dorsal (RMGD) foi introduzido em 1906. Contudo, apenas 70 anos após sua primeira descrição, ele ganhou popularidade como uma opção para as reconstruções mamárias. Método: Estudo clínico retrospectivo realizado por meio da coleta de dados de 22 pacientes submetidas à reconstrução mamária imediata com emprego do RMGD associado a implante de silicone durante o período de fevereiro de 2012 a dezembro de 2013. Resultados: Não houve necrose do retalho de grande dorsal ou perda da reconstrução mamária nos casos estudados. Foram observados 10 casos (45%) de seroma em região dorsal, 3 casos (14%) de necrose parcial da pele da mastectomia e 3 casos (14%) de deiscência parcial da ferida operatória. Não foram evidenciados fatores de risco com significância estatística para as complicações apresentadas. Ocorreram 4 casos (18,18%) de alterações de cobertura do implante, com atrofia muscular e cutânea, e 2 casos (9,09%) de contratura capsular. Apenas um caso não foi associado à radioterapia. Contudo, não houve significância estatística em relação à radioterapia adjuvante e às complicações tardias apresentadas (p = 0,635). Conclusão: O RMGD associado ao implante de silicone é uma opção segura e confiável para a reconstrução mamária imediata após mastectomias.


Introduction: The first effective breast cancer treatment was described in 1894. Less aggressive surgeries were developed in the 1960s and 70s, without increased mortality due to cancer. With similar historical evolution, the latissimus dorsi muscle flap (LDMF) procedure was introduced in 1906. Seventy years after its first description, LDMF gained popularity as an option for breast reconstruction. Method: A retrospective clinical study was conducted using data obtained from 22 patients undergoing immediate breast reconstruction with LDMF and silicone implants between February 2012 and December 2013. Results: No latissimus dorsi flap necrosis or breast reconstruction losses were observed in this study. Ten cases (45%) of seroma were detected in the dorsal region, three cases (14%) of partial necrosis of the mastectomized skin, and three cases (14%) of partial surgical wound dehiscence. Statistical significant risk factors for the complications observed have not been emphasized. There were four cases (18.18%) of muscle and skin atrophy associated with implants, and two cases (9.09%) of capsular contracture. Only one case was not associated with radiotherapy. However, there were no statistically significant differences in adjuvant radiotherapy and late complications (p = 0.635). Conclusion: LDMF associated with silicone implants is a safe and reliable option for immediate breast reconstruction after mastectomies.


Assuntos
Humanos , Feminino , Adulto , Pessoa de Meia-Idade , Idoso , História do Século XXI , Retalhos Cirúrgicos , Mama , Neoplasias da Mama , Cefadroxila , Estudos Retrospectivos , Implantes de Mama , Procedimentos de Cirurgia Plástica , Géis de Silicone , Glândulas Mamárias Humanas , Estudo Clínico , Retalhos Cirúrgicos/cirurgia , Mama/cirurgia , Mama/patologia , Neoplasias da Mama/cirurgia , Neoplasias da Mama/patologia , Cefadroxila/uso terapêutico , Cefadroxila/farmacologia , Implantes de Mama/efeitos adversos , Implantes de Mama/normas , Procedimentos de Cirurgia Plástica/métodos , Géis de Silicone/uso terapêutico , Glândulas Mamárias Humanas/cirurgia , Glândulas Mamárias Humanas/patologia
18.
Anesth Prog ; 61(2): 53-62, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-24932978

RESUMO

It has been reported that the action of infiltration anesthesia on the jawbone is attenuated significantly by elevation of the periosteal flap with saline irrigation in clinical studies; however, the reason is unclear. Therefore, the lidocaine concentration in mandibular bone after subperiosteal infiltration anesthesia was measured under several surgical conditions. The subjects were 48 rabbits. Infiltration anesthesia by 0.5 mL of 2% lidocaine with 1 : 80,000 epinephrine (adrenaline) was injected into the right mandibular angle and left mandibular body, respectively. Under several surgical conditions (presence or absence of periosteal flap, and presence or absence of saline irrigation), both mandibular bone samples were removed at a fixed time after subperiosteal infiltration anesthesia. The lidocaine concentration in each mandibular bone sample was measured by high-performance liquid chromatography. As a result, elevation of the periosteal flap with saline irrigation significantly decreased the lidocaine concentration in the mandibular bone. It is suggested that the anesthetic in the bone was washed out by saline irrigation. Therefore, supplemental conduction and/or general anesthesia should be utilized for long operations that include elevation of the periosteal flap with saline irrigation.


Assuntos
Anestésicos Locais/análise , Lidocaína/análise , Mandíbula/química , Periósteo/cirurgia , Cloreto de Sódio/administração & dosagem , Retalhos Cirúrgicos/cirurgia , Irrigação Terapêutica/métodos , Anestesia Local/métodos , Anestésicos Locais/administração & dosagem , Animais , Densidade Óssea/fisiologia , Cromatografia Líquida de Alta Pressão , Imageamento Tridimensional/métodos , Injeções , Lidocaína/administração & dosagem , Masculino , Coelhos , Fatores de Tempo , Microtomografia por Raio-X/métodos
19.
Ann Plast Surg ; 72(3): 318-22, 2014 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-23241783

RESUMO

BACKGROUND: Wedge resections of the helical rim may result in a significant deformity of the ear with the ear not only smaller but cupped and prominent too. Our technique involves resection of the wedge in the scaphal area without extending into the concha followed by advancement of the helical rim into the defect. This technique is most suitable for peripheral defects of the helical rim, in the middle third. METHODS: Our modified surgical technique was applied to reconstruction of the pinna after resection of the tumor in 12 patients. Free cartilaginous helical rim, length of helical rim to be resected, and projection of the ear from the mastoid was measured. This was then compared with measurements after the operation, and the patient satisfaction assessed with a visual analog scale. RESULTS: The free cartilaginous rim was 91.67 ± 5.61 mm. Of this, 21.92 ± 3.78 mm was resected, which amounted to 23.84% ± 3.35% of the rim. Although this resulted in a mean increase in ear projection of 6.42 ± 1.68 mm, the aesthetic outcome was good (visual analog scale, 9.08 ± 0.9). CONCLUSIONS: This technique reduces cupping and does not make the ear as prominent as it may do after a conventional wedge resection and results in high patient satisfaction.


Assuntos
Carcinoma Basocelular/cirurgia , Carcinoma de Células Escamosas/cirurgia , Pavilhão Auricular/cirurgia , Neoplasias da Orelha/cirurgia , Estética , Procedimentos de Cirurgia Plástica/métodos , Neoplasias Cutâneas/cirurgia , Retalhos Cirúrgicos/cirurgia , Idoso , Idoso de 80 Anos ou mais , Humanos , Masculino , Pessoa de Meia-Idade , Satisfação do Paciente
20.
J Contemp Dent Pract ; 14(4): 751-3, 2013 Jul 01.
Artigo em Inglês | MEDLINE | ID: mdl-24309360

RESUMO

Secondary alveolar bone grafting is a method that enables an excellent oral rehabilitation of the patients having cleft palate. Many types of bone grafts have been used for reconstruction of the cleft, including autogenous bone and bone substitutes. Platelet-rich fibrin (PRF) has been shown to be effective in grafting the defect. The aim of this presentation is to report the closure of an alveolar cleft with the use of symphyseal bone grafts harvested with platelet rich fibrin under local anesthesia. PRF may be a good treatment choice depending on the early radiographical view of the defect and uneventfull healing.


Assuntos
Enxerto de Osso Alveolar/métodos , Anestesia Local/métodos , Transplante Ósseo/métodos , Plasma Rico em Plaquetas/fisiologia , Adolescente , Criança , Seguimentos , Humanos , Masculino , Mandíbula/cirurgia , Bloqueio Nervoso/métodos , Procedimentos de Cirurgia Plástica/métodos , Retalhos Cirúrgicos/cirurgia , Coleta de Tecidos e Órgãos/métodos , Sítio Doador de Transplante/cirurgia
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