Efficacy and safety evaluation of acupuncture therapy for patients with salpingitis in IVF-ET: A protocol of systematic review and meta-analysis.

BACKGROUND: As an alternative for salpingitis in IVF-ET, acupuncture has gradually attracted the attention of clinicians based on the theory of syndrome differentiation and treatment of Chinese traditional medicine. However, due to the lack of evidence-based medical evidence, the author designed the program to evaluate the effectiveness and safety of acupuncture. METHODS: From the beginning to August 2020, 7 electronic databases will be searched. Two of our researchers will independently conduct research selection, data extraction, and risk assessment of bias. We will use Review Manager 5.3 software for meta-analysis and heterogeneity assessment. In addition, we will use the grading of recommendations assessment, development, and evaluation to evaluate the evidence quality. RESULTS: This study will demonstrate an evidence-based review of acupuncture for salpingitis in IVF-ET. CONCLUSION: The study will provide clear evidence to assess the effectiveness and side effects of acupuncture for salpingitis in IVF-ET. TRIAL REGISTRATION NUMBER: INPLASY2020110125.

Terapia Su Jok en pacientes con diagnóstico de hidrosalpinx / Su Jok therapy in patients with hydrosalpinx diagnosis

Se realizó un estudio cuasiexperimental de 56 pacientes con diagnóstico de hidrosalpinx, que acudieron a la consulta de Medicina Natural y Tradicional del Hospital General Docente Dr Juan Bruno Zayas Alfonso de Santiago de Cuba - remitidas de las consultas de Ginecología e Infertilidad -, desde septiembre de 2014 hasta diciembre de 2015, para evaluar la respuesta a la terapia Su Jok. Entre las variables analizadas figuraron: edad, factores de riesgo, manifestaciones clínicas, síndromes tradicionales, evolución clínica y respuesta al tratamiento. En la casuística predominaron las féminas de 30-39 años, la enfermedad inflamatoria pélvica y las infecciones de trasmisión sexual como antecedentes patológicos (71,4 por ciento), el dolor y la secreción vaginal como síntomas principales, así como el estancamiento de Qi de hígado, Qi de riñón no firme y frío-humedad en bazo como síndromes más frecuentes. Finalmente, se logró una evolución favorable y una respuesta adecuada al tratamiento

A quasi-experiment of 56 patients with hydrosalpinx diagnosis that went to the Natural and Traditional Medicine Service of Dr Juan Bruno Zayas Alfonso Teaching General Hospital in Santiago de Cuba - referred from the Gynecology and Infertility Services -, was carried out from September, 2014 to December, 2015, to evaluate the response to Su Jok therapy. Among the analyzed variables there were: age, risk factors, clinical features, traditional syndromes, clinical course and response to the treatment. In the case material there was a prevalence of women aged 30-39, pelvic inflammatory disease and sexually transmitted infections as pathological history (71.4 percent), pain and vaginal secretion as main symptoms, as well as Qi liver stagnation, not firm Qi kidney and coldness-humidity in spleen as most frequent syndromes. Finally, there was a favorable clinical course and an appropriate response to the treatment

Chrono- and Immunocorrection of Inflammatory Disorders of Internal Reproductive Organs in Women of Reproductive Age.

We compared the effectiveness of immunomodulators used in the treatment of patients with chronic salpingitis and oophoritis with or without changes in succinate dehydrogenase (SDH) activity in blood lymphocytes at incubation with the drug. Diurnal variations in individual reaction of SDH in blood lymphocytes to thymalin or ridostin were revealed. In the groups of women receiving ridostin or thymalin during the reaction of lymphocyte SDH to it, improvement of clinical laboratory and immunological parameters was observed in the majority of the patients and no effect was found in a lesser group of patients than in the groups treated with drugs during the absence of lymphocyte SDH reaction thereto. The timing of the presence of SDH reaction to drugs in the immunocompetent cells makes it possible to set the optimal daily regime of their application and to select a drug that would be most effective in each particular case.

[Low-intensity laser irradiation in the combined treatment of depressive disoreders in patients with chronic salpingo-oophoritis].

This study was designed to evaluate the possibility to use low-intensity laser radiation in combined therapy of somatogenic depressions in patients having gynecological problems, such as inflammatory disease of uterine appendages. It was shown that the combined treatment including administration ofantidepressants significantly accelerated the development of beneficial changes and stabilized depressive manifestations. Inclusion of low-intensity laser irradiation in the combined therapy further improved its positive effect. Nevertheless, the complete recovery could not be achieved in the absence of specific antidepressant treatment despite the alleviation of depressive symptoms.

[Chronic salpingo-oophoritis: clinical and physiological rationale for therapeutic application of impulse low-frequency electrostatic field].

Significant alterations in arterial and venous circulation, primarily in the vascular bed of the small pelvis, were detected in 63 patients with chronic salpingo-oophoritis. All the women received intensive therapy with impulse low-frequency electrostatic field (ILFEF). In 52 women the exposure was abdominovaginal, in 11 women the exposure was preceded by placebo procedures. ILFEF produced marked and long-term positive effects (up to 18 months): pain relief, reduction of vegetative anxiety, increased uterine motility, softening and better elasticity of the commissures in the regions of the uterine appendages, normalization of the circulation in the vascular bed of the small pelvis. This therapy is pathogenetically sound as it rests on changes in activity of central regulation resultant from trigger stimulation and normalization of hemodynamics in the vascular bed of the small pelvis (in 76.6%) especially in the veins in response to stimulation of the sympathetic nerves in the inflammation focus.

[Amplipulse-magnetotherapy and iodine-bromine waters in combined treatment of patients with chronic nonspecific salpingo-oophoritis].

Amplipulse-magnetotherapy was used as monotherapy and in combined treatment of 110 patients with chronic nonspecific salpingo-oophoritis (CNSO). Clinical assessment shows that transcerebral amplipulse-megnetotherapy (TAMT) has a positive effects on the course of CNSO, reproductive system and psychoemotional status of the patients. The addition of physical and balneological factors to TAMT enhances and prolongs neurotropic, endocrine, analgetic and anti-inflammatory effects of TAMT.

[Electrophoresis of sulphide mud extract in combined therapy of chronic inflammatory diseases of uterine appendages (an experimental and clinical study)]. / Elektroforez ékstrakta ilovoi sul'fidnoi griazi v kompleksnoi terapii khronicheskikh vospalitel'nykh zabolevanii pridatkov matki (éksperimentalno-klinicheskoe issledovanie).

On the original experimental model of chronic inflammation of the ovaries and oviducts in white rats it was established that electrophoresis of 1% esobel solution prevents an increase in the specific volume of interstitial connective tissue, development of fibrosclerotic alterations and adhesive process. Peloidophysiotherapy normalizes growth and atresia of the ovarian follicular system. Thus, electrophoresis of 1% esobel solution is highly effective in combined treatment of chronic inflammatory diseases of the uterine appendages.

[The adaptogenic effects of hyperbaric oxygenation within the complex therapy of inflammation diseases of the internal female genitals]. / Adaptogennye éffekty giberbaricheskoi oksigenatsii v kompleksnoi terapii vospalitel'nykh zabolevanii zhenskikh polovykh organov.

The effects of hyperbaric oxygenation (HBO), when used jointly with the routine complex therapy, made in the clinical signs of inflammatory diseases of the internal female genitals as well as in the lipid peroxidation/antioxidant system were investigated within the case study. The reaction of the antioxidant system to the HBO action was found to depend on a degree of its original exhaustion. An opinion was put forward on the need in the individual approach to whether to add the HBO method to the complex therapy or not. If the reaction to the hyperbaric effects is positive, the HBO method must be used to the full extent. If there is progressing of the exhaustion degree of the antioxidant system, the HBO course must be interrupted.

[Interference therapy in combined treatment of patients with chronic nonspecific salpingoophoritis]. / Iterferentsterapiia v kompleksnom lechenii bol'nykh khronicheskim nespetsificheskim sal'pingooforitom.

Neurotropic interference therapy (NIT) was studied as monotherapy and in combination with iodine-bromide water in 50 patients with chronic nonspecific salpingoophoritis. NIT was found effective in the above disease as it improved clinical picture, reproductive function, psychoemotional condition of the patients. The addition of iodine-bromide water to NIT potentiates and prolongs neurotropic, endocrine, analgetic and anti-inflammatory effects of NIT.

Les infections de l'arbre génito-urinaire / The infections of the genito-urinary tree

Les infections génito-urinaires sont dominées, en terme de fréquence, par les cystites et les vaginites: ce sont des consultations quotidiennes qui permettent d'affiner progressivement notre connaissance de l'homéopathie à la lumière de l'efficacité des remèdes prescrits. (AU)

Infecciones genitales debidas a Chlamydia trachomatis / Genital infections caused by Chlamydia trachomatis

C. trachomatis es la bacteria más frecuentemente involucrada en la etiología de las enfermedades de transmisión sexual. En la mujer la cervicitis, que se puede complicar con endometritis, salpingitis e infertilidad, es la presentación clínica más común. Sin embargo, la mayoría de las infecciones genitales en la mujer son asintomáticas. En el hombre la uretritis y la epididimitis son formas frecuentes de presentación. El diagnóstico de las infecciones por C. trachomatis se puede hacer por métodos de detección de antígenos incluyendo la amplificación de los ácidos nucleicos. Dependiendo de la presentación clínica diversos protocolos de tratamiento se pueden implementar (AU)

Positive effect of balneotherapy on post-PID symptoms.

OBJECTIVE: The aim of this study was investigation of effect of balneotherapy after antibiotic treatment of PID. PATIENTS AND INTERVENTIONS: Fifty-seven patients with PID, diagnosed by laparoscopy, were treated by the same antibiotic scheme (oxytetracycline and metronidazole). After treatment of the acute phase, we studied the effect of balneotherapy (mud baths or mud packs, mineral baths, electrotherapies, and gynecological exercises) under sanatorium conditions in 30 patients. Twenty-seven patients without balneotherapy served as a control group. Second-look laparoscopy with dye insufflation was carried out about 12 weeks after the first operation. RESULTS: The rate of tubal occlusion after balneotherapy was 31% vs. 28% in patients without balneotherapy (P > .05). Moderate or severe adhesions seen at first look were similar in both groups (40.7% vs. 46.7%) and were nearly unchanged during second-look laparoscopy (44.4% vs. 46.6%). Twelve of 27 (44.4%) control patients had subjective or objective complaints compared to only 2 of 30 (6.7%, P < .05). CONCLUSION: Although balneotherapy after antibiotic therapy for acute PID does not improve fallopian tube patency, it is useful to reduce the frequency of lower abdominal pain.

[The action of sinusoidal modulated currents with different parameters in experimental chronic infectious salpingitis]. / Deistvie sinusoidal'nykh modulirovannykh tokov razlichnykh parametrov pri khronicheskom infektsionnom sal'pingite v éksperimente.

Sinusoidal modulated current (SMC) varying in parameters was applied according to the conventional technique versus an original one developed by the author. The experiment was performed on 66 fertile rabbits with chronic salpingitis. Histological, histochemical and biochemical findings support the advantages of the SMC regimen proposed by the author.

[Acupuncture therapy in the comprehensive treatment of salpingo- oophoritis]. / Iglorefleksoterapiia v kompleksnom lechenii sal'pingooforitov.

Follow-up and therapy of 136 patients with nonspecific salpingo-oophoritis evidence the efficacy of acupuncture included in a complex of therapeutic measures for the treatment of this condition, as compared to traditional therapeutic modalities. Acupuncture therapy is conductive to shortening in-hospital therapy, to full-value normalization of the body immunobiologic defense and of the autonomic nervous system, and to a reduction of the incidence of the condition recurrences.

[The interference-current therapy of chronic salpingo-oophoritis (a trial of studying the regional hemodynamics)]. / Interferentsionnaia terapiia khronicheskogo sal'pingooforita (opyt izucheniia regionarnoi gemodinamiki).

Blood redistribution in blood circulatory beds (the uterus, external genitalia and vagina) and as a whole have been established in exposure to interference currents. Ka index of rheoencephalography may be used as an additional objective criterion of individual sufficiency of physiotherapeutic exposure.

[Use of sinusoidal modulated currents with various parameters in treating tubal sterility]. / Izpolzvane na sinusoidalni modulirani tokove s razlichni parametri pri lechenie na tubarnoto bezplodie.

Treatment with sinusoidal modulating currents, applied by two various methods, was used in 89 women with tubal sterility. An original method, proposed by the authors, was compared with known and most frequently used up to now method for treatment of chronic salpingo-oophoritis with sinusoidal modulating currents. In two groups of patients, treated by the method developed by the authors, conception was established in 20.7% and 32.43% against 8.7% of the patients, treated by a control method. The authors think that parameters of action due to sinusoidal modulating currents established by them, are more efficient and recommend the method, developed by them, to be used more widely in therapeutic practice by the consulting offices of sterility in our country.