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1.
Am Surg ; 90(2): 190-198, 2024 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-37522359

RESUMO

BACKGROUND: Intraoperative radiation therapy (IORT) in select populations is a viable alternative to whole breast radiation therapy (WBRT) in the treatment of biopsy-proven localized invasive and non-invasive breast cancer. We aim to assess recurrence and complication rates following IORT in lumpectomy patients at a community hospital in Baltimore City. METHODS: An IRB-approved retrospective cohort study was conducted on consecutive cases of lumpectomy with IORT from 2013 through 2020 by a single surgeon. Patient demographics, tumor and operative characteristics, and complications were retrieved from electronic medical records. Primary outcomes were postoperative complications and local recurrence rates. RESULTS: The final cohort included 117 patients with mean follow-up time of 2.60 + 1.78 years. Mean age was 69.84 + 8.77 years. Thirty-three (28.21%) of patients developed a seroma. Odds of seroma formation were mildly significant for skin spacing [OR: 1.18, 95% CI: (1.02-1.37)] and balloon fill volume [1.04 (1.00-1.08)], but not for age, BMI, diabetes, former or current smoking status, history of WBRT, tumor size, or balloon size. Three (2.6%) patients had local recurrence. Odds of local recurrence were mildly significant for increased tumor size [1.14 (1.04-1.24)] and not significant for any other covariates. CONCLUSIONS: IORT exposure did not confer higher rates of complications and the local recurrence rate mirrored that of the general population undergoing lumpectomy and WBRT. This study demonstrates the need for equitable treatment options based on individual needs: IORT is a safe alternative to WBRT in certain subpopulations, especially those with physical, social, or personal limitations preventing participation in a 3- to 7-week time commitment of WBRT.


Assuntos
Neoplasias da Mama , Humanos , Pessoa de Meia-Idade , Idoso , Feminino , Neoplasias da Mama/radioterapia , Neoplasias da Mama/cirurgia , Neoplasias da Mama/patologia , Estudos Retrospectivos , Seroma , Mama/patologia , Terapia Combinada , Mastectomia Segmentar , Cuidados Intraoperatórios , Recidiva Local de Neoplasia/epidemiologia , Recidiva Local de Neoplasia/cirurgia
2.
Spine (Phila Pa 1976) ; 48(18): 1326-1334, 2023 Sep 15.
Artigo em Inglês | MEDLINE | ID: mdl-37326447

RESUMO

STUDY DESIGN: This is a basic science, animal research study. OBJECTIVE: This study aims to explore, in rodent models, the effectiveness of systemic nonsteroidal anti-inflammatory drugs in reducing recombinant human bone morphogenetic protein-2 (rhBMP-2) induced neuroinflammation. SUMMARY OF BACKGROUND DATA: rhBMP-2 is increasingly used to augment fusion in lumbar interbody fusion surgeries, although it can cause complications including postoperative radiculitis. MATERIALS AND METHODS: Eighteen 8-week-old Sprague-Dawley rats underwent Hargreaves testing to measure the baseline thermal withdrawal threshold before undergoing surgical intervention. The L5 nerve root was exposed and wrapped with an Absorbable Collagen Sponge containing rhBMP-2. Rats were randomized into 3 groups: (1) Low dose (LD), (2) high dose (HD) diclofenac sodium, and (3) saline, receiving daily injection treatment. Hargreaves testing was performed postoperatively on days 5 and 7. Seroma volumes were measured by aspiration and the nerve root was then harvested for hematoxylin and eosin, immunohistochemistry, Luxol Fast Blue staining, and real-time quantitative polymerase chain reaction. The Student t test was used to evaluate the statistical significance among groups. RESULTS: The intervention groups showed reduced seroma volume, and a general reduction of inflammatory markers (MMP12, MAPK6, GFAP, CD68, and IL18) compared with controls, with the reduction in MMP12 being statistically significant ( P = 0.02). Hematoxylin and eosin and immunohistochemistry of the nerve roots showed the highest macrophage density in the saline controls and the lowest in the HD group. Luxol Fast Blue staining showed the greatest extent of demyelination in the LD and saline groups. Lastly, Hargreaves testing, a functional measure of neuroinflammation, of the HD group demonstrated a minimal change in thermal withdrawal latency. In contrast, the thermal withdrawal latency of the LD and saline groups showed a statistically significant decrease of 35.2% and 28.0%, respectively ( P < 0.05). CONCLUSION: This is the first proof-of-concept study indicating that diclofenac sodium is effective in alleviating rhBMP-2-induced neuroinflammation. This can potentially impact the clinical management of rhBMP-2-induced radiculitis. It also presents a viable rodent model for evaluating the effectiveness of analgesics in reducing rhBMP-2-induced inflammation.


Assuntos
Radiculopatia , Fusão Vertebral , Humanos , Ratos , Animais , Diclofenaco/efeitos adversos , Seroma/induzido quimicamente , Seroma/tratamento farmacológico , Doenças Neuroinflamatórias , Roedores , Ratos Sprague-Dawley , Radiculopatia/tratamento farmacológico , Amarelo de Eosina-(YS)/efeitos adversos , Hematoxilina/farmacologia , Metaloproteinase 12 da Matriz/farmacologia , Fator de Crescimento Transformador beta/uso terapêutico , Proteína Morfogenética Óssea 2/farmacologia , Proteínas Recombinantes/farmacologia , Proteínas Recombinantes/uso terapêutico , Vértebras Lombares/cirurgia
3.
Plast Reconstr Surg ; 151(1): 20e-30e, 2023 01 01.
Artigo em Inglês | MEDLINE | ID: mdl-36194076

RESUMO

SUMMARY: The breast implant capsule is a dynamic structure that forms following the implantation of a device. Although normally benign, increased awareness of breast implant-associated anaplastic large-cell lymphoma (BIA-ALCL) highlights that disease may arise from the capsule. BIA-ALCL presents as a late seroma or mass but explains few of the late seromas found in breast implant patients. To date, many of these seromas lack a clear cause and are often described as "idiopathic." Several benign and malignant breast implant capsular diseases can cause a late seroma or mass, including breast implant-associated squamous cell carcinoma. Similar to early reports of BIA-ALCL, these conditions are rare and largely limited to case reports or series. The purpose of this special topic is to present a narrative review highlighting capsular abnormalities that contribute to the formation of late seroma or mass in an attempt to broaden the differential diagnosis and help plastic surgeons identify the cause. Specifically, we review the presentation and management of BIA-ALCL, synovial metaplasia, capsular epithelialization, late hematoma, double capsule, breast cancer, squamous cell carcinoma, mesenchymal tumor, and B-cell lymphoma. Although rare, plastic surgeons should consider these capsular conditions as causes of late seromas and masses. Usually, these conditions may be diagnosed by following the National Comprehensive Cancer Network screening guidelines for BIA-ALCL. Thorough evaluation and workup of late seromas and masses may lead to improved characterization of these rare breast implant capsular conditions and improve our understanding of their pathophysiology and management.


Assuntos
Implante Mamário , Implantes de Mama , Neoplasias da Mama , Linfoma Anaplásico de Células Grandes , Humanos , Feminino , Linfoma Anaplásico de Células Grandes/diagnóstico , Linfoma Anaplásico de Células Grandes/etiologia , Linfoma Anaplásico de Células Grandes/terapia , Implantes de Mama/efeitos adversos , Seroma/diagnóstico , Seroma/etiologia , Seroma/terapia , Implante Mamário/efeitos adversos , Mama/cirurgia , Neoplasias da Mama/etiologia , Neoplasias da Mama/cirurgia , Neoplasias da Mama/diagnóstico
4.
Hernia ; 26(5): 1369-1379, 2022 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-35575863

RESUMO

PURPOSE: The purpose of this study is to present a concept combining three modifications of the component separation technique (CST) in one procedure as an original solution for the management of complex subcostal abdominal wall hernia. METHODS: Between January 2010 and January 2020, seven patients presenting at the high-volume academic center with complex subcostal hernia underwent surgery in which three modifications of CST were combined into one procedure. Major complex subcostal hernia was defined by either width or length of the defect being greater than 10 cm. The following were the stages of the operative technique: (a) the "method of wide myofascial release" at the side of the hernia defect; (b) "open-book variation" of the component separation technique at the opposite side of the hernia defect; (c) a modified component separation technique for closure of midline abdominal wall hernias in the presence of enterostomies; (d) suturing of the myofascial flaps to each other to cover the defect; and (e) repair augmentation with an absorbable mesh in the onlay position. RESULTS: The median length and width of the complex subcostal hernias were 15 cm (10-19) and 15 cm (8-24), respectively. The overall morbidity rate was 57.1% (wound infection occurred in three patients, seroma in two patients, and skin necrosis in one patient). There was no hernia recurrence during the median follow-up period of 19 months. CONCLUSION: The operative technique integrating three modifications of CST in one procedure with onlay absorbable mesh reinforcement is a feasible solution for the management of complex subcostal abdominal wall hernia.


Assuntos
Parede Abdominal , Hérnia Ventral , Parede Abdominal/cirurgia , Hérnia Ventral/cirurgia , Herniorrafia/efeitos adversos , Herniorrafia/métodos , Humanos , Recidiva , Seroma , Retalhos Cirúrgicos , Telas Cirúrgicas
5.
Dermatol Surg ; 47(2): 245-249, 2021 02 01.
Artigo em Inglês | MEDLINE | ID: mdl-33565777

RESUMO

BACKGROUND: Suction-curettage using an arthroscopic shaver is the most effective surgical treatment for bromhidrosis; however, information regarding the procedure is limited. This study investigated the factors that affect the efficacy of suction-curettage. PATIENTS AND METHODS: We retrospectively evaluated data for 215 patients (430 axillae) with bromhidrosis treated with suction-curettage using an arthroscopic shaver between 2011 and 2019. RESULTS: Excellent or good efficacy with improved malodor was achieved in 418 axillae (97.21%). Secondary suction-curettage was performed for 11 (2.56%), with excellent results. Efficacy and need for secondary suction-curettage were not associated with age, sex, shaving time, and tumescent infiltration use. Complications were observed in 52 (12.09%) axillae, including hematoma or seroma, epidermis decortication, skin necrosis, and infections; 10 (2.33%) required local debridement for wounds. Complications showed a significant difference with respect to age (p < .001). Pain scores on postoperative Day 2 were significantly lower for patients treated using tumescent infiltration than those for the others (1.65 ± 0.84 vs 4.57 ± 1.16; p < .001). CONCLUSION: The results suggest that 7 to 15 minutes of suction curettage using an arthroscopic shaver is sufficient to achieve good efficacy for bromhidrosis with few complications. Older age was a risk factor for complications, and tumescent infiltration use achieved good postoperative pain control. LEVELS OF EVIDENCE: II.


Assuntos
Anestesia Local , Curetagem/instrumentação , Epinefrina , Hiperidrose/cirurgia , Infecção da Ferida Cirúrgica/etiologia , Vasoconstritores , Anestésicos Locais , Axila/cirurgia , Curetagem/efeitos adversos , Desbridamento , Feminino , Hematoma/etiologia , Humanos , Lidocaína , Masculino , Necrose/etiologia , Necrose/cirurgia , Odorantes , Dor Pós-Operatória/etiologia , Reoperação , Estudos Retrospectivos , Seroma/etiologia , Pele/patologia , Sucção/instrumentação , Infecção da Ferida Cirúrgica/cirurgia
6.
Am J Otolaryngol ; 41(6): 102616, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32645535

RESUMO

BACKGROUND: Implantable hypoglossal nerve stimulation (HNS) has been found to be a safe and effective therapy for patients with obstructive sleep apnea, and patient adherence to treatment has been found to be as high as 86% after 12 months of therapy. OBJECTIVE: The purpose of this study is to review the medical device reports (MDRs) submitted to the Food and Drug Administration's (FDA) Manufacturer and User Device Facility Experience (MAUDE) database to identify adverse events related to HNS therapy that could hinder compliance. METHODS: A search of the FDA MAUDE database was conducted using the product code "MNQ" for "Inspire stimulator for sleep apnea." Reports of adverse events associated with Inspire for sleep apnea from January 2000 to May 2020 were included for analysis. From these included reports, event variables were collected, including event setting, adverse event to patient, iatrogenic injury, device malfunction, interventions, and root causes. Results were compiled and reviewed. RESULTS: The search query yielded 180 reports that met inclusion criteria, containing a total of 196 adverse events. The most commonly reported adverse events to patients were infection (n = 50, 34.2%), neuropraxia (n = 22, 15.1%) and hematoma/seroma (n = 17, 11.6%). A total of 83 adverse events (42.3%) required reoperation. The most common reoperations performed for adverse events to patients were explantation (n = 30, 46.2%) and device repositioning/lead revision (n = 24, 36.9%), while the most common reoperation performed for device malfunctions was device replacement (n = 10, 55.6%). CONCLUSION: In attempting to further improve patient compliance, understanding these device malfunctions and adverse events related to HNS implantation or usage is crucial for the identification of potential causes of patient non-adherence.


Assuntos
Bases de Dados Factuais , Terapia por Estimulação Elétrica/efeitos adversos , Terapia por Estimulação Elétrica/instrumentação , Nervo Hipoglosso/fisiologia , Neuroestimuladores Implantáveis/efeitos adversos , Apneia Obstrutiva do Sono/cirurgia , Apneia Obstrutiva do Sono/terapia , Remoção de Dispositivo , Falha de Equipamento , Feminino , Hematoma/epidemiologia , Hematoma/etiologia , Humanos , Infecções/epidemiologia , Infecções/etiologia , Masculino , Reoperação , Seroma/epidemiologia , Seroma/etiologia
7.
World J Surg ; 44(5): 1526-1537, 2020 05.
Artigo em Inglês | MEDLINE | ID: mdl-31900568

RESUMO

BACKGROUND: Negative pressure wound therapy (NPWT) is a promising advance in the management of closed surgical incisions. NPWT application induces several effects locally within the wound including reduced lateral tension and improving lymphatic drainage. As a result, NPWT may improve wound healing and reduce surgical site complications. We aim to evaluate the efficacy of prophylactic application of NPWT in preventing surgical site complications for closed incisions in breast surgery. METHODS: This systematic review was reported according to PRISMA guidelines. The protocol was published in PROSPERO (CRD42018114625). Medline, Embase, CINAHL and Cochrane Library databases were searched for studies which compare the efficacy of NPWT versus non-NPWT dressings for closed incisions in breast surgery. Specific outcomes of interest were total wound complications, surgical site infection (SSI), seroma, haematoma, wound dehiscence and necrosis. RESULTS: Seven studies (1500 breast incisions in 904 patients) met the inclusion criteria. NPWT was associated with a significantly lower rate of total wound complications [odds ratio (OR) 0.36; 95% CI 0.19-069; P = 0.002], SSI (OR 0.45; 95% CI 0.24-0.86; P = 0.015), seroma (OR 0.28; 95% CI 0.13-0.59; P = 0.001), wound dehiscence (OR 0.49; 95% CI 0.32-0.72; P < 0.001) and wound necrosis (OR 0.38; 95% CI 0.19-0.78; P = 0.008). There was no significant difference in haematoma rate (OR 0.8; 95% CI 0.19-3.2; P = 0.75). Statistically significant heterogeneity existed for total wound complications, but no other outcomes. CONCLUSION: Compared with conventional non-NPWT dressings, prophylactic application of NPWT is associated with significantly fewer surgical site complications including SSI, seroma, wound dehiscence and wound necrosis for closed breast incisions.


Assuntos
Hematoma/prevenção & controle , Tratamento de Ferimentos com Pressão Negativa , Deiscência da Ferida Operatória/prevenção & controle , Infecção da Ferida Cirúrgica/prevenção & controle , Ferida Cirúrgica/terapia , Bandagens , Mama/cirurgia , Humanos , Seroma/prevenção & controle , Cicatrização
8.
Rev. argent. cir. plást ; 25(2): 54-67, apr-jun.2019. tab, fig
Artigo em Espanhol | BINACIS, LILACS | ID: biblio-1152220

RESUMO

Introducción. El linfedema de miembro superior postratamiento del cáncer de mama es una afección progresiva y crónica que compromete a una gran cantidad de pacientes causando efectos físicos, psicológicos y sociales. El linfedema secundario se da en un 20-40% de los casos luego de la cirugía del cáncer de mama con vaciamiento y radioterapia. Este es un problema desafiante. El tratamiento conservador ha demostrado no ser suficientemente exitoso por lo que su tratamiento quirúrgico es una buena opción. La transferencia microquirúrgica de nódulo linfático vascularizado (TNLV) brindó una nueva esperanza para este grupo de pacientes. Material y métodos. En el periodo comprendido entre marzo 2016 y agosto 2018 se analizaron 16 pacientes con una edad promedio de 50,25. Se realizó tratamiento quirúrgico basándose en la transferencia de nódulo linfático vascularizado (TNLV) de la ingle a la axila por medio de una anastomosis microquirúrgica de la arteria circunfleja ilíaca superficial en pacientes que presentaron linfedema secundario al tratamiento del cáncer de mama. Se realizó simultáneamente a la cirugía reconstructiva de la mama con colgajo libre DIEP y también en un segundo tiempo quirúrgico. Tiempo quirúrgico de 4,3 horas y una estadía en internación de 2,3 días. Resultados. La vitalidad de los colgajos fue 100%. Como morbilidad, se presentaron cuatro casos de seroma, una infección y una dehiscencia en la zona dadora. Con un seguimiento promedio de 10,43 meses y una reducción significativa de volumen del miembro afectado del 27.47% en comparación con el preoperatorio. La incidencia de celulitis descendió. La linfografía posoperatoria indicó una mejoría en el drenaje linfático del miembro afectado. Conclusiones. La transferencia linfática vascularizada al miembro afectado en conjunto con la cirugía reconstructiva mamaria DIEP es un procedimiento seguro y eficaz en el tratamiento del linfedema de miembro superior en pacientes mastectomizadas con vaciamiento ganglionar y radioterapia.


Purpose: Upper limb lymphedema post breast cancer treatment is a progressive and chronic condition that involves a large number of patients causing psychological, physical and social effects. The incidence of secondary lymphedema is about 20-40% before breast cancer treatment. This is a challenging problem. The conservative treatment has shown not to be successful enough so the surgery is a really good option. The vascularized lymph node transfer (VLNT) offers some hope to this group of patients. The purpose of the investigation is to demonstrate that te VLNT is an efficacious approach to treating postmastectomy upper limb lymphedema. Methods: From March 2016 to August 2018 were analyzed sixteen patients with a mean age of 50.25 years. They all have secondary lymphedema. They underwent surgical treatment based on vascularized lymph node transfer from the groin to the axially area or elbow as a recipent site. The deep inferior epigastric perforator flap was made at the same time, as a stacked flap. In only six cases, the VLNT was made on a second surgical time. The serrato's vessels were used as a recipient vessels in the axilary area and a radial artery branch and the cephalic vein were used in the elbow. Results: The flaps vitality was 100%. There were four seroma cases, one infection and one dehiscence. At a mean follow up of 10.43, the mean circumference reduction rate of the lymphedematous limb was about 27.47% between the preoperative and the postoperative groups. The postoperative lymphoscintigrapy showed a little improvement. The follow up of the vitality of the nodes was made by a lymphatic contrast tomography, and it showed all nodes survived. Conclusions: The vascularized lymph node transfer and the DIEP flap were confirmed as an effective and safe treatment to the secondary lymphedema in this type of patients, and it really improves postmastectomy upper limb lymphedema


Assuntos
Humanos , Anastomose Cirúrgica , Estudos Retrospectivos , Procedimentos de Cirurgia Plástica , Seroma , Retalhos de Tecido Biológico , Linfedema Relacionado a Câncer de Mama/diagnóstico , Artéria Ilíaca , Linfonodos , Linfedema/diagnóstico
9.
BMC Cancer ; 19(1): 99, 2019 Jan 23.
Artigo em Inglês | MEDLINE | ID: mdl-30674296

RESUMO

BACKGROUND: Seroma formation is the most common complication after mastectomy and places patients at risk of associated morbidities. Microporous polysaccharide hemospheres (MPH) consists of hydrophilic, plant based, polysaccharide particles and is currently used as an absorbable hemostatic agent. An animal model evaluating MPH and seroma formation after mastectomy with axillary lymph node dissection showed a significant decrease in seroma volume. Study aim was to evaluate topical MPH on the risk of post-mastectomy seroma formation as measured by total drain output and total drain days. METHODS: Prospective randomized single-blinded clinical trial of patients undergoing mastectomy for the treatment of breast cancer. MPH was applied to the surgical site in the study group and no application in the control group. RESULTS: Fifty patients were enrolled; eight were excluded due to missing data. Forty-two patients were evaluated, control (n = 21) vs. MPH (n = 21). No difference was identified between the two groups regarding demographics, tumor stage, total drain days, total drain output, number of clinic visits, or complication rates. On a subset analysis, body mass index (BMI) greater than 30 was identified as an independent risk factor for high drain output. Post hoc analyses of MPH controlling for BMI also revealed no statistical difference. CONCLUSIONS: Unlike the data presented in an animal model, no difference was demonstrated in the duration and quantity of serosanguinous drainage related to the use of MPH in patients undergoing mastectomy for the treatment of breast cancer. BMI greater than 30 was identified as an independent risk factor for high drain output and this risk was not affected by MPH use. NCT03647930, retrospectively registered 08/2018.


Assuntos
Drenagem/métodos , Hemostáticos/administração & dosagem , Mastectomia/reabilitação , Polissacarídeos/administração & dosagem , Ferida Cirúrgica/tratamento farmacológico , Administração Tópica , Idoso , Neoplasias da Mama/cirurgia , Drenagem/estatística & dados numéricos , Feminino , Humanos , Mastectomia/efeitos adversos , Pessoa de Meia-Idade , Extratos Vegetais/administração & dosagem , Complicações Pós-Operatórias/etiologia , Complicações Pós-Operatórias/prevenção & controle , Estudos Prospectivos , Seroma/etiologia , Seroma/prevenção & controle , Método Simples-Cego , Ferida Cirúrgica/etiologia , Resultado do Tratamento
10.
Phys Ther ; 99(2): 229-239, 2019 02 01.
Artigo em Inglês | MEDLINE | ID: mdl-30339213

RESUMO

Background and Purpose: Axillary web syndrome (AWS) and seroma are common and function-limiting side effects following treatments for breast cancer. Studies of AWS and seroma are rare, and there are no guidelines for physical therapy in these cases. Case Description: After left breast lumpectomy due to invasive ductal carcinoma, a 65-year-old female patient underwent intraoperative radiation therapy and whole breast radiation. Seven months later, during treatment for breast swelling, AWS and breast seroma were identified by a physical therapist certified in lymphedema treatment. Treatment goals were to reduce breast swelling and pain and to improve shoulder movements. Interventions included manual lymph drainage, left arm stretching, and instruction about self-lymphatic-drainage and stretching exercise. Also, a compression bra was ordered, and continued daily activities and physical activity were recommended. Outcomes: Improvement in shoulder movement, breast swelling, and pain. Discussion: Because evidence for treatment guidelines following treatments for breast cancer is lacking, close follow-up for treatment-related complications is recommended. Management should be chosen according to signs and symptoms. Realistic expectations can reduce patient frustration and improve coping strategies and compliance with self-treatment demands. Clinical studies to support these conclusions are required.


Assuntos
Axila/fisiopatologia , Doenças Linfáticas/terapia , Linfedema/terapia , Mastectomia/efeitos adversos , Modalidades de Fisioterapia , Seroma/terapia , Idoso , Feminino , Humanos , Doenças Linfáticas/etiologia , Complicações Pós-Operatórias/etiologia , Seroma/etiologia , Síndrome
11.
Surg Endosc ; 31(1): 324-332, 2017 01.
Artigo em Inglês | MEDLINE | ID: mdl-27287903

RESUMO

BACKGROUND: Laparoscopic ventral hernia repair (LVHR) demonstrates comparable recurrence rates, but lower incidence of surgical site infection (SSI) than open repair. Delayed complications can occur with intraperitoneal mesh, particularly if a subsequent abdominal operation is required, potentially resulting in bowel injury. Robotic retromuscular ventral hernia repair (RRVHR) allows abdominal wall reconstruction (AWR) and extraperitoneal mesh placement previously only possible with open repair, with the wound morbidity of LVHR. METHODS: All LVHR and RRVHR performed in our institution between June 2013 and May 2015 contained in the Americas Hernia Society Quality Collaborative database were analyzed. Continuous bivariate analysis was performed with Student's t test. Continuous nonparametric data were compared with Chi-squared test, or Fisher's exact for small sample sizes. p values <0.05 were considered significant. RESULTS: We compared 103 LVHR with 53 RRVHR. LVHR patients were older (60.2 vs. 52.9 years; p = 0.001), but demographics were otherwise similar between groups. Hernia width was similar (6.9 vs. 6.5 cm, p = 0.508). Fascial closure was achieved more often with RRVHR (96.2 vs. 50.5 %; p < 0.001) and aided by myofascial release in 43.4 %. Mesh was placed in an intraperitoneal position in 90.3 % of LVHR and extraperitoneal in 96.2 % of RRVHR. RRVHR operative time was longer (245 vs. 122 min, p < 0.001). Narcotic requirement was similar between LVHR and RRVHR (1.8 vs. 1.4 morphine equivalents/h; p = 0.176). Seroma was more common after RRVHR (47.2 vs. 16.5 %, p < 0.001), but SSI was similar (3.8 vs. 1 %, p = 0.592). Median length of stay was shorter after RRVHR (1 vs. 2 days, p = 0.004). Direct hospital cost was similar (LVHR $13,943 vs. RRVHR $19,532; p = 0.07). CONCLUSION: RRVHR enables true AWR, with myofascial release to offset tension for midline fascial closure, and obviates the need for intraperitoneal mesh. Perioperative morbidity of RRVHR is comparable to LVHR, with shorter length of stay despite a longer operative time and extensive tissue dissection.


Assuntos
Hérnia Ventral/cirurgia , Laparoscopia , Procedimentos Cirúrgicos Robóticos , Feminino , Hérnia Ventral/economia , Custos Hospitalares , Humanos , Tempo de Internação/estatística & dados numéricos , Masculino , Pessoa de Meia-Idade , Duração da Cirurgia , Complicações Pós-Operatórias , Seroma/etiologia , Telas Cirúrgicas , Infecção da Ferida Cirúrgica/etiologia , Estados Unidos
12.
Minerva Chir ; 72(4): 311-316, 2017 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-28008753

RESUMO

BACKGROUND: Tension-free hernia repair has been recognized as the gold standard for the treatment of inguinal hernia. Different mesh has different characteristics that influence the efficiency of surgery. We conducted this study to evaluate the effectiveness of non-woven mesh in preperitoneal tension-free inguinal hernia repair under local anesthesia. METHODS: The medical records of patients who received preperitoneal tension-free inguinal hernia repair under local anesthesia in our hospital from 2012 to 2015 were reviewed. Patients were included if their surgery was conducted using non-woven or woven mesh. Outcome measures were operation time, length of stay in hospital, hospital fees, complications and degree of chronic pain, foreign body sensation and recurrence. A total of 389 cases were included. 186 cases were repaired with non-woven mesh (observation group), and 203 cases were repaired with woven mesh (control group). RESULTS: There were no significant differences in operation time and length of stay in the hospital, but hospital fees were significantly higher in the observation group. Seroma of the inguinal region occurred in 6 cases of the observation group and 8 cases of the control group with no significant difference and no other complications and recurrence in both groups. No cases of chronic pain were recorded in the observation group; 8 cases were recorded in the control group. Foreign body sensation was found in 1 case of the observation group and 9 cases in the control group, which showed attractive advantages of non-woven mesh. CONCLUSIONS: Preperitoneal tension-free repair for inguinal hernia under local anesthesia using non-woven or woven mesh is available. The hospital cost of using non-woven mesh is higher than that of woven mesh, but the incidence rate of chronic pain and foreign body sensation are lower in the use of non-woven mesh. Therefore, non-woven mesh may be worth using in the clinical setting.


Assuntos
Anestesia Local , Hérnia Inguinal/cirurgia , Herniorrafia , Polipropilenos , Telas Cirúrgicas , Idoso , Anestesia Local/economia , Índice de Massa Corporal , China , Estudos de Coortes , Feminino , Seguimentos , Hérnia Inguinal/economia , Herniorrafia/efeitos adversos , Herniorrafia/economia , Custos Hospitalares , Hospitais Universitários , Humanos , Masculino , Pessoa de Meia-Idade , Duração da Cirurgia , Dor Pós-Operatória/etiologia , Estudos Retrospectivos , Fatores de Risco , Seroma/etiologia , Telas Cirúrgicas/efeitos adversos , Telas Cirúrgicas/economia , Técnicas de Sutura , Têxteis , Resultado do Tratamento
13.
Rev. colomb. radiol ; 27(2): 4434-4440, 2016. ilus, graf
Artigo em Espanhol | LILACS | ID: biblio-987409

RESUMO

Introducción: En la actualidad, la mamoplastia de aumento con implantes es un procedimiento cada vez más común, con fines exclusivamente cosméticos o reconstructivos después de una mastectomía. Existen complicaciones locales ampliamente conocidas, como la ruptura y contracturas capsulares, pero también se le han atribuido otras complicaciones menos frecuentes, como el linfoma anaplásico y el síndrome autoinmune/inflamatorio inducido por adyuvantes (ASIA). Objetivo: Revisar las características por imagen de las complicaciones frecuentes e infrecuentes asociadas al aumento mamario con prótesis. Metodología: Recolección retrospectiva de casos con complicaciones relacionadas con implantes mamarios; revisión y edición de las diferentes modalidades de imágenes en pacientes de la clínica Fundación Valle del Lili de Cali durante los dos últimos años. Resultados: Es frecuente encontrar cambios postquirúrgicos por mamoplastia de aumento con implantes. Aunque la mamografía tiene un papel limitado en la valoración de las complicaciones del implante, continúa siendo la herramienta de tamizaje de cáncer en la mama aumentada. La ecografía es un instrumento muy útil y costo-efectivo en la evaluación de los implantes. La RM con secuencias de silicona es la modalidad con más alta sensibilidad y especificidad si se quiere valorar la integridad del implante y el tejido mamario en su conjunto.


Introduction: At present, breast augmentation with implants is an increasingly common procedure, be it solely for cosmetic reasons or for reconstructive purposes after mastectomy. There are widely known local complications associated with this intervention, such as implant rupture and encapsulation, but there are other less common complications too, such as anaplastic lymphoma and autoimmune/inflammatory syndrome induced by adjuvants (ASIA). Objective: To review the imaging characteristics of frequent and infrequent complications associated with breast augmentation with implants. Methodology: Cases of different complications were retrospectively collected, in order to review mammography, ultrasound, CT and MRI images of patients with such complications at the Fundación Valle del Lili Clinic (Cali, Colombia) over the past two years. Conclusions: It is common to find post-surgical changes due to breast augmentation with implants. The study concludes that although mammography has a limited role in the assessment of implant complications, it remains the main screening tool for cancer in augmented breasts. Ultrasound is a very useful and cost-effective tool in evaluating implants. MRI with silicone sequences has the highest sensitivity and specificity when assessing the integrity of the implant and breast tissue as a whole. Key words (MeSH) Breast implants Implant capsular contracture Seroma Adjuvants, immunologic


Assuntos
Humanos , Implantes de Mama , Adjuvantes Imunológicos , Seroma , Contratura Capsular em Implantes
14.
Artigo em Inglês | WPRIM | ID: wpr-159395

RESUMO

The keystone flap is a fascia-based island flap with two conjoined V-Y flaps. Here, we report a case of successful treatment of a trochanter pressure sore patient with the traditional keystone flap. A 50-year-old male patient visited our department with a 3×5 cm pressure sore (grade III) to the left of the greater trochanter that was covered with eschar. Debridement was done and the defect size increased to 5×8 cm in an elliptical shape. Doppler ultrasound was then used to locate the inferior gluteal artery perforator near the wound. The keystone flap was designed to the medial side. The perforator based keystone island flap covered the defect without resistance. The site remained clean, and no dehiscence, infection, hematoma, or seroma developed. In general, greater trochanter pressure sores are covered with a perforator based propeller flap or fascia lata flap. However, these flaps have the risk of pedicle kinking and require a large operation site. For the first time, we successfully applied the keystone flap to treat a greater trochanter pressure sore patient. Our design was also favorable with the relaxation skin tension lines. We conclude that the keystone flap including a perforator is a reliable option to reconstruct trochanteric pressure sores.


Assuntos
Humanos , Masculino , Pessoa de Meia-Idade , Artérias , Desbridamento , Fascia Lata , Fêmur , Hematoma , Úlcera por Pressão , Relaxamento , Seroma , Pele , Ultrassonografia , Ferimentos e Lesões
16.
Ann Otol Rhinol Laryngol ; 123(11): 749-53, 2014 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-24847161

RESUMO

OBJECTIVE: Auricular seroma is a cystic swelling filled with serous fluid. It occurs spontaneously or following trauma. Successful treatment of the seroma remains a challenge because this disease has a high propensity for recurrence. The aim was to study the results of the Plaster of Paris (POP) cast in treatment of seroma in terms of complete resolution of swelling, recurrence, and auricular aesthesis. STUDY DESIGN: Prospective. SETTING: Smt. Kashibai Navale Medical College and General Hospital. MATERIALS AND METHODS: A total of 48 patients with auricular seroma were studied. They were treated with aspiration of the cyst followed by compression dressing with a POP cast, taking the contour of the pinna. The POP cast was kept for 3 days. The patients were followed up for 6 months for recurrence. RESULTS: Out of 48 patients, 43 patients had complete resolution of the swelling in a single application of the POP cast. Five patients needed 2 applications of the POP cast. Not a single patient had recurrence. Temporary discoloration or thickening of the pinna was noted in 8 patients. No major complications like perichondritis were noted. CONCLUSION: Aspiration and contour dressing using POP is an innovative and effective treatment for management of auricular seroma as it prevents surgical trauma and recurrence and gives cosmetically excellent results.


Assuntos
Bandagens , Moldes Cirúrgicos , Pavilhão Auricular , Otopatias/terapia , Seroma/terapia , Adulto , Sulfato de Cálcio , Drenagem , Edema/etiologia , Edema/terapia , Seguimentos , Humanos , Masculino , Estudos Prospectivos
17.
Aesthetic Plast Surg ; 38(2): 479-81, 2014 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-24488003

RESUMO

Herbal medicine is a multibillion-pound industry, and surveys suggest that ~10% of the UK population uses herbal supplements concurrently with prescription medications. Patients and health care practitioners are often unaware of the adverse side effects of herbal medicines. In addition, because many of these herbal supplements are available over the counter, many patients do not disclose these when listing medications to health care providers. A 39-year-old nurse underwent an abdominoplasty with rectus sheath plication after weight loss surgery. Postoperatively, she experienced persistent drain output, and after discharge, a seroma developed requiring repeated drainage in the clinic. After scar revision 10 months later, the woman bled postoperatively, requiring suturing. Again, a seroma developed, requiring repeated drainage. It was discovered that the patient had been taking a herbal menopause supplement containing ingredients known to have anticoagulant effects. Complementary medicine is rarely taught in UK medical schools and generally not practiced in UK hospitals. Many supplements are known to have anticoagulant, cardiovascular, and sedative effects. Worryingly, questions about herbal medicines are not routinely asked in clinics, and patients do not often volunteer such information. With the number and awareness of complementary medications increasing, their usage among the population is likely to increase. The authors recommend specific questioning about the use of complementary medications and consideration of ceasing such medications before surgery. Level of Evidence V This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .


Assuntos
Abdominoplastia/métodos , Suplementos Nutricionais/efeitos adversos , Fitoterapia/efeitos adversos , Hemorragia Pós-Operatória/induzido quimicamente , Seroma/etiologia , Abdominoplastia/efeitos adversos , Adulto , Anticoagulantes/efeitos adversos , Cirurgia Bariátrica/métodos , Drenagem/métodos , Feminino , Seguimentos , Humanos , Obesidade Mórbida/diagnóstico , Obesidade Mórbida/cirurgia , Contagem de Plaquetas , Complicações Pós-Operatórias/diagnóstico , Complicações Pós-Operatórias/cirurgia , Hemorragia Pós-Operatória/fisiopatologia , Recidiva , Medição de Risco , Seroma/fisiopatologia , Seroma/terapia , Resultado do Tratamento , Redução de Peso
18.
Rev. bras. cir. plást ; 29(4): 609-624, 2014. ilus
Artigo em Inglês, Português | LILACS | ID: biblio-825

RESUMO

INTRODUÇÃO: Com base na grande variedade de possíveis sequelas e intercorrências de cirurgias estéticas e no papel da nutrição no processo de recuperação dessas, percebe-se a necessidade de práticas terapêuticas que garantam eficácia do resultado estético final. MÉTODO: O presente estudo caracteriza-se como uma revisão não sistemática que associou possíveis nutrientes, compostos bioativos e fitoterápicos que previnam ou amenizem seroma e fibrose no pós operatório. Para tanto, foram utilizados artigos de revistas científicas do meio eletrônico, legislações nacionais e livros didáticos, publicados entre os anos de 2002 e 2012. RESULTADOS: Demonstrou-se que as principais causas de seroma e fibrose são cicatrização alterada, inflamação, estresse oxidativo e edema. Dessa forma, foi elaborado um guia prático com os nutrientes, compostos bioativos e fitoterápicos que podem ser utilizados a fim de prevenir, controlar ou amenizar as complicações no pós-cirúrgico de procedimentos estéticos. CONCLUSÃO: Salientou-se que para o tratamento das condições abordadas é fundamental que haja um trabalho multiprofissional, enfatizando um acompanhamento médico, nutricional e fisioterápico que abranja as alterações conhecidas na fisiopatologia de seroma e fibrose.


INTRODUCTION: Based on the wide range of possible consequences and complications of plastic surgery and the role of nutrition in the recovery process of these, we see the need for therapeutic practices to ensure effectiveness of the final aesthetic result. METHOD: This study is characterized as a non-systematic review of the possible associated nutrients, bioactive compounds and herbal medicines to prevent seroma and fibrosis. Thus, we used scientific journal articles from electronic media, national laws and textbooks published between 2002 and 2012. RESULTS: We demonstrated that the main causes of seroma and fibrosis are changed healing, inflammation, oxidative stress and edema. Thus, we designed a practical guide with nutrients, bioactive compounds and herbal medicines that can be used to prevent, control or mitigate the complications after plastic surgery. CONCLUSION: It was emphasized that for the treatment of covered conditions is essential that there is a multidisciplinary approach, emphasizing a medical, nutritional and therapeutic monitoring covering the known changes in the pathophysiology of seroma and fibrosis.


Assuntos
Humanos , Complicações Pós-Operatórias , Fibrose , Nutrientes , Revisão , Artigo de Revista , Seroma , Publicação Periódica , Portais de Acesso a Revistas Científicas , Ciências da Nutrição , Fitoterapia , Complicações Pós-Operatórias/cirurgia , Fibrose/cirurgia , Fibrose/complicações , Fibrose/patologia , Nutrientes/análise , Nutrientes/uso terapêutico , Seroma/cirurgia , Seroma/complicações , Alimento Funcional , Alimento Funcional/análise , Alimento Funcional/normas , Ciências da Nutrição/métodos , Ciências da Nutrição/normas , Fitoterapia/métodos , Fitoterapia/normas
19.
J Plast Reconstr Aesthet Surg ; 66(12): 1773-6, 2013 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-23751975

RESUMO

Since 1995, the association between Anaplastic Large Cell Lymphoma (ALCL) and breast implant capsules has been of increasing concern. Up to 40 cases have been reported worldwide. The majority of cases favour an indolent course, similar to that of primary cutaneous ALCL, with a 10-year survival rate of greater than 90%. Many recommendations have been made for diagnosis, treatment and adjuvant therapy but the issue of reconstruction post capsulectomy and removal of implants has not yet been addressed. We present a case report and management option.


Assuntos
Implantes de Mama/efeitos adversos , Neoplasias da Mama/etiologia , Neoplasias da Mama/cirurgia , Linfoma Anaplásico de Células Grandes/etiologia , Linfoma Anaplásico de Células Grandes/cirurgia , Seroma/patologia , Adulto , Implante Mamário , Neoplasias da Mama/patologia , Neoplasias da Mama/radioterapia , Remoção de Dispositivo , Fracionamento da Dose de Radiação , Feminino , Humanos , Linfoma Anaplásico de Células Grandes/patologia , Linfoma Anaplásico de Células Grandes/radioterapia , Recidiva , Reoperação , Seroma/etiologia , Géis de Silicone
20.
World J Surg Oncol ; 10: 275, 2012 Dec 19.
Artigo em Inglês | MEDLINE | ID: mdl-23253298

RESUMO

BACKGROUND: Seroma formation is a frequent complication following radical lymph node dissection (RLND) in patients with metastatic melanoma. Several strategies have been used to prevent fluid accumulation and thereby reduce the duration of postoperative drainage, including fibrin sealants. METHODS: This was a prospective, single-center study in which consecutive patients undergoing surgical treatment of stage III metastatic melanoma by axillary or ilio-inguinal RLND were randomized to receive standard treatment plus fibrinogen/thrombin-coated collagen sealant patch (CSP) or standard treatment alone. The primary endpoint of the study was postoperative duration of drainage. RESULTS: A total of 70 patients underwent axillary (n = 47) or ilio-inguinal (n = 23) RLND and received CSP plus standard treatment (n = 37) or standard treatment alone (n = 33). Mean duration of drainage was significantly reduced in the CSP group compared with standard treatment (ITT analysis: 20.1 ± 5.1 versus 23.3 ± 5.1 days; p = 0.010). The percentage of patients drainage-free on day 21 was significantly higher in the CSP group compared with the standard treatment group (86% versus 67%; p = 0.049). CONCLUSIONS: Use of the tissue sealant resulted in a significant reduction in duration of drainage. Further studies are warranted to confirm these results in different and selected types of lymphadenectomy.


Assuntos
Colágeno/uso terapêutico , Adesivo Tecidual de Fibrina/uso terapêutico , Fibrinogênio/uso terapêutico , Excisão de Linfonodo/efeitos adversos , Melanoma/cirurgia , Seroma/prevenção & controle , Neoplasias Cutâneas/cirurgia , Trombina/uso terapêutico , Adulto , Idoso , Idoso de 80 Anos ou mais , Axila , Drenagem , Combinação de Medicamentos , Feminino , Virilha , Humanos , Metástase Linfática , Masculino , Melanoma/secundário , Pessoa de Meia-Idade , Estudos Prospectivos , Neoplasias Cutâneas/secundário
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