Antinociception caused by the extract of Hedyosmum brasiliense and its active principle, the sesquiterpene lactone 13-hydroxy-8,9-dehydroshizukanolide.

Trentin, A P; Santos, A R; Guedes, A; Pizzolatti, M G; Yunes, R A; Calixto, J B

Trentin, A P; Santos, A R; Guedes, A; Pizzolatti, M G; Yunes, R A; Calixto, J B.

Affiliation

Trentin AP; Departamento de Farmacologia, Universidade Federal de Santa Catarina, Florianópolis, Brazil.

Planta Med ; 65(6): 517-21, 1999 Aug.

Article in En | MEDLINE | ID: mdl-10483370

Subject(s)

Analgesics/pharmacology; Pain/drug therapy; Plant Extracts/pharmacology; Plants, Medicinal; Sesquiterpenes/pharmacology; Acetic Acid/toxicity; Animals; Brazil; Constriction, Pathologic; Male; Mice; Molecular Structure; Pain/etiology; Plant Extracts/chemistry; Plant Leaves; Plant Stems; Sesquiterpenes/chemistry; Sesquiterpenes/isolation & purification

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Database: MEDLINE Therapeutic Methods and Therapies TCIM: Terapias_biologicas Main subject: Pain / Plants, Medicinal / Sesquiterpenes / Plant Extracts / Analgesics Type of study: Etiology_studies Country/Region as subject: America do sul / Brasil Language: En Journal: Planta Med Year: 1999 Type: Article Affiliation country: Brazil

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