In vitro relaxation of rabbit and human internal anal sphincter by rutaecarpine, an alkaloid isolated from Evodia rutaecarpa.

Jiang, J K; Chiu, J H; Yu, I T; Lin, J K

Jiang, J K; Chiu, J H; Yu, I T; Lin, J K.

Affiliation

Jiang JK; Department of Surgery, Veterans General Hospital-Taipei, Taiwan, Republic of China.

Life Sci ; 66(24): 2323-35, 2000 May 05.

Article in En | MEDLINE | ID: mdl-10864095

Subject(s)

Alkaloids/pharmacology; Anal Canal/drug effects; Drugs, Chinese Herbal/pharmacology; Muscle Relaxation/drug effects; Muscle, Smooth/drug effects; Vasodilator Agents/pharmacology; Acetylcholine/pharmacology; Animals; Calcium/metabolism; Dose-Response Relationship, Drug; Edetic Acid/pharmacology; Enzyme Inhibitors/pharmacology; Ethylmaleimide/pharmacology; Humans; In Vitro Techniques; Indole Alkaloids; Male; Methylene Blue/pharmacology; Muscle, Smooth/pathology; NG-Nitroarginine Methyl Ester/pharmacology; Nifedipine/pharmacology; Quinazolines; Rabbits; Species Specificity

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Database: MEDLINE Traditional Medicines: Medicinas_tradicionales_de_asia / Medicina_china Main subject: Anal Canal / Vasodilator Agents / Drugs, Chinese Herbal / Alkaloids / Muscle Relaxation / Muscle, Smooth Language: En Journal: Life Sci Year: 2000 Type: Article Affiliation country: China

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