Dietary nucleotides increase the proportion of a TCR gammadelta+ subset of intraepithelial lymphocytes (IEL) and IL-7 production by intestinal epithelial cells (IEC); implications for modification of cellular and molecular cross-talk between IEL and IEC by dietary nucleotides.

Nagafuchi, S; Totsuka, M; Hachimura, S; Goto, M; Takahashi, T; Yajima, T; Kuwata, T; Kaminogawa, S

Nagafuchi, S; Totsuka, M; Hachimura, S; Goto, M; Takahashi, T; Yajima, T; Kuwata, T; Kaminogawa, S.

Affiliation

Nagafuchi S; Nutrition Science Institute, Meiji Milk Products Co., Ltd., Odawara, Kanagawa, Japan. n-shinya@mx7.mesh.ne.jp

Biosci Biotechnol Biochem ; 64(7): 1459-65, 2000 Jul.

Article in En | MEDLINE | ID: mdl-10945264

Subject(s)

Cytidine Monophosphate/metabolism; Dietary Supplements; Guanosine Monophosphate/metabolism; Inosine Monophosphate/metabolism; Interleukin-7/biosynthesis; Receptors, Antigen, T-Cell, gamma-delta/metabolism; T-Lymphocyte Subsets/metabolism; Uridine Monophosphate/metabolism; Animals; Epithelial Cells/metabolism; Female; Humans; Intestinal Mucosa/cytology; Intestinal Mucosa/metabolism; Lymphocyte Count; Mice; Mice, Inbred BALB C; Receptors, Interleukin-2/biosynthesis; Receptors, Interleukin-7/biosynthesis; T-Lymphocyte Subsets/classification; T-Lymphocyte Subsets/cytology

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Database: MEDLINE Main subject: Uridine Monophosphate / T-Lymphocyte Subsets / Interleukin-7 / Receptors, Antigen, T-Cell, gamma-delta / Guanosine Monophosphate / Dietary Supplements / Cytidine Monophosphate / Inosine Monophosphate Language: En Journal: Biosci Biotechnol Biochem Year: 2000 Type: Article Affiliation country: Japan

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