Diet-induced hyperhomocysteinemia exacerbates neointima formation in rat carotid arteries after balloon injury.

Morita, H; Kurihara, H; Yoshida, S; Saito, Y; Shindo, T; Oh-Hashi, Y; Kurihara, Y; Yazaki, Y; Nagai, R

Morita, H; Kurihara, H; Yoshida, S; Saito, Y; Shindo, T; Oh-Hashi, Y; Kurihara, Y; Yazaki, Y; Nagai, R.

Affiliation

Morita H; Department of Cardiovascular Medicine, Graduate School of Medicine, University of Tokyo, Japan.

Circulation ; 103(1): 133-9, 2001 Jan 02.

Article in En | MEDLINE | ID: mdl-11136698

Subject(s)

Angioplasty, Balloon/adverse effects; Carotid Artery Diseases/pathology; Homocysteine/administration & dosage; Hyperhomocysteinemia/pathology; Tunica Intima/drug effects; Administration, Oral; Animals; Carotid Arteries/drug effects; Carotid Arteries/pathology; Carotid Arteries/physiology; Carotid Artery Diseases/complications; Carotid Artery Diseases/metabolism; Cystine/blood; Diet; Dose-Response Relationship, Drug; Folic Acid/blood; Folic Acid/pharmacology; Homocysteine/blood; Homocysteine/toxicity; Hyperhomocysteinemia/chemically induced; Hyperhomocysteinemia/complications; In Vitro Techniques; Male; Methionine/blood; Rats; Rats, Sprague-Dawley; Tunica Intima/injuries; Tunica Intima/metabolism; Tunica Intima/pathology; Vasoconstriction/drug effects; Vasoconstriction/physiology; Vasoconstrictor Agents/pharmacology; Vasodilator Agents/pharmacology

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Database: MEDLINE Main subject: Carotid Artery Diseases / Tunica Intima / Angioplasty, Balloon / Hyperhomocysteinemia / Homocysteine Type of study: Risk_factors_studies Language: En Journal: Circulation Year: 2001 Type: Article Affiliation country: Japan

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