Synthesis and evaluation of novel 2-oxo-1,2-dihydro-3-quinolinecarboxamide derivatives as potent and selective serotonin 5-HT4 receptor agonists.

Suzuki, M; Ohuchi, Y; Asanuma, H; Kaneko, T; Yokomori, S; Ito, C; Isobe, Y; Muramatsu, M

Suzuki, M; Ohuchi, Y; Asanuma, H; Kaneko, T; Yokomori, S; Ito, C; Isobe, Y; Muramatsu, M.

Affiliation

Suzuki M; Research Center Taisho Pharmaceutical Co., Ltd., Ohmiya, Saitama, Japan. s13845@ccm.taisho.co.jp

Chem Pharm Bull (Tokyo) ; 49(1): 29-39, 2001 Jan.

Article in En | MEDLINE | ID: mdl-11201221

Subject(s)

Amides/chemical synthesis; Amides/pharmacology; Quinolines/chemical synthesis; Quinolines/pharmacology; Receptors, Serotonin/drug effects; Serotonin Receptor Agonists/chemical synthesis; Serotonin Receptor Agonists/pharmacology; Animals; Dogs; Drug Evaluation, Preclinical; Female; Gastrointestinal Motility/drug effects; Male; Receptors, Serotonin, 5-HT4; Spectrum Analysis

Search on Google

Add to My VHL

XML

PubMed Links

Database: MEDLINE Main subject: Quinolines / Receptors, Serotonin / Serotonin Receptor Agonists / Amides Language: En Journal: Chem Pharm Bull (Tokyo) Year: 2001 Type: Article Affiliation country: Japan

Search on Google

Add to My VHL

XML

PubMed Links