New triterpenes, myrrhanol A and myrrhanone A, from guggul-gum resins, and their potent anti-inflammatory effect on adjuvant-induced air-pouch granuloma of mice.

Kimura, I; Yoshikawa, M; Kobayashi, S; Sugihara, Y; Suzuki, M; Oominami, H; Murakami, T; Matsuda, H; Doiphode, V V

Kimura, I; Yoshikawa, M; Kobayashi, S; Sugihara, Y; Suzuki, M; Oominami, H; Murakami, T; Matsuda, H; Doiphode, V V.

Affiliation

Kimura I; Department of Clinical Pharmacology, Graduate School of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University, Sugitani, Japan. ikukokim@ms.toyama-mpu.ac.jp

Bioorg Med Chem Lett ; 11(8): 985-9, 2001 Apr 23.

Article in En | MEDLINE | ID: mdl-11327606

Subject(s)

Anti-Inflammatory Agents/pharmacology; Exudates and Transudates/drug effects; Granuloma/drug therapy; Neovascularization, Pathologic/drug therapy; Triterpenes/pharmacology; Animals; Anti-Inflammatory Agents/chemistry; Anti-Inflammatory Agents/therapeutic use; Carmine/analysis; Cell Movement/drug effects; Commiphora; Dose-Response Relationship, Drug; Freund's Adjuvant; Granuloma/chemically induced; Male; Mice; Plant Extracts/chemistry; Plant Gums; Terpenes/pharmacology; Terpenes/therapeutic use; Triterpenes/chemical synthesis; Triterpenes/chemistry; Triterpenes/therapeutic use

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Database: MEDLINE Main subject: Triterpenes / Exudates and Transudates / Granuloma / Anti-Inflammatory Agents / Neovascularization, Pathologic Language: En Journal: Bioorg Med Chem Lett Year: 2001 Type: Article Affiliation country: Japan

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