Synthesis of nitrogen analogues of salacinol and their evaluation as glycosidase inhibitors.

Ghavami, A; Johnston, B D; Jensen, M T; Svensson, B; Pinto, B M

Ghavami, A; Johnston, B D; Jensen, M T; Svensson, B; Pinto, B M.

Affiliation

Ghavami A; Department of Chemistry, Simon Fraser University, Burnaby, British Columbia, Canada V5A 1S6.

J Am Chem Soc ; 123(26): 6268-71, 2001 Jul 04.

Article in En | MEDLINE | ID: mdl-11427050

Subject(s)

Amylases/antagonists & inhibitors; Diabetes Mellitus/drug therapy; Enzyme Inhibitors/chemistry; Plant Extracts/chemistry; Quaternary Ammonium Compounds/chemistry; Sugar Alcohols/chemistry; Sugar Alcohols/chemical synthesis; Sulfates; Animals; Arabinose; Carbohydrate Sequence; Enzyme Inhibitors/therapeutic use; Erythritol; Glucan 1,4-alpha-Glucosidase/antagonists & inhibitors; Humans; Imino Furanoses; Indolizines/chemistry; Isoenzymes; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Molecular Structure; Monosaccharides/chemistry; Monosaccharides/therapeutic use; Plant Extracts/therapeutic use; Quaternary Ammonium Compounds/therapeutic use; Stereoisomerism; Sugar Alcohols/therapeutic use; Swine; alpha-Amylases/antagonists & inhibitors

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Database: MEDLINE Main subject: Sugar Alcohols / Sulfates / Plant Extracts / Diabetes Mellitus / Enzyme Inhibitors / Quaternary Ammonium Compounds / Amylases Language: En Journal: J Am Chem Soc Year: 2001 Type: Article

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