Adenocarcinoma/drug therapy; Antineoplastic Agents/therapeutic use; Prostatic Neoplasms/drug therapy; Adenocarcinoma/genetics; Adenocarcinoma/metabolism; Adenocarcinoma/pathology; Angiogenesis Inhibitors/pharmacology; Angiogenesis Inhibitors/therapeutic use; Animals; Antibodies, Monoclonal/pharmacology; Antibodies, Monoclonal/therapeutic use; Antineoplastic Agents/classification; Antineoplastic Agents/pharmacology; Apoptosis/drug effects; Cell Cycle/drug effects; Cell Cycle Proteins/antagonists & inhibitors; Clinical Trials as Topic; Drug Design; Drug Screening Assays, Antitumor; Enzyme Inhibitors/pharmacology; Enzyme Inhibitors/therapeutic use; Gene Expression Regulation, Neoplastic/drug effects; Growth Substances/physiology; Humans; Male; Neoplasm Proteins/antagonists & inhibitors; Neoplasm Proteins/physiology; Neovascularization, Pathologic/drug therapy; Oncogene Proteins/antagonists & inhibitors; Oncogene Proteins/physiology; Phytotherapy; Plant Preparations/therapeutic use; Prostatic Neoplasms/genetics; Prostatic Neoplasms/metabolism; Prostatic Neoplasms/pathology; Receptors, Cell Surface/antagonists & inhibitors; Receptors, Cell Surface/physiology; Recombinant Fusion Proteins/pharmacology; Recombinant Fusion Proteins/therapeutic use; Signal Transduction/drug effects; Tumor Cells, Cultured/drug effects