A newly established strain of spontaneously hypertensive rat with a defect of ascorbic acid biosynthesis.

Horio, F; Hayashi, K; Mishima, T; Takemori, K; Oshima, I; Makino, S; Kakinuma, A; Ito, H

Horio, F; Hayashi, K; Mishima, T; Takemori, K; Oshima, I; Makino, S; Kakinuma, A; Ito, H.

Affiliation

Horio F; Department of Applied Molecular Biosciences, Graduate School of Bioagricultural Sciences, Nagoya University, Japan. horiof@agr.nagoya-u.ac.jp

Life Sci ; 69(16): 1879-90, 2001 Sep 07.

Article in En | MEDLINE | ID: mdl-11693268

Subject(s)

Ascorbic Acid Deficiency/genetics; Disease Models, Animal; Hypertension/genetics; Rats, Inbred SHR/genetics; Aging/physiology; Alkaline Phosphatase/blood; Animals; Animals, Congenic; Arteries/drug effects; Arteries/pathology; Ascorbic Acid/blood; Ascorbic Acid/pharmacology; Blood Pressure/drug effects; Blood Pressure/physiology; Epinephrine/blood; Heterozygote; Hypertension/blood; L-Gulonolactone Oxidase; Liver/enzymology; Male; Norepinephrine/blood; Rats; Rats, Mutant Strains; Sugar Alcohol Dehydrogenases/genetics; Testis/blood supply; Testis/pathology

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Database: MEDLINE Main subject: Ascorbic Acid Deficiency / Rats, Inbred SHR / Disease Models, Animal / Hypertension Language: En Journal: Life Sci Year: 2001 Type: Article Affiliation country: Japan

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