Novel human HALR (MLL3) gene encodes a protein homologous to ALR and to ALL-1 involved in leukemia, and maps to chromosome 7q36 associated with leukemia and developmental defects.

Tan, Y C; Chow, V T

Tan, Y C; Chow, V T.

Affiliation

Tan YC; Department of Microbiology, Faculty of Medicine, National University of Singapore, Kent Ridge.

Cancer Detect Prev ; 25(5): 454-69, 2001.

Article in En | MEDLINE | ID: mdl-11718452

Subject(s)

Chromosomes, Human, Pair 7/genetics; DNA-Binding Proteins/genetics; Leukemia/genetics; Neoplasm Proteins; Proto-Oncogenes; Transcription Factors; Amino Acid Sequence; Base Sequence; Blotting, Northern; Chromosome Mapping; Cloning, Molecular; DNA, Complementary/analysis; DNA, Neoplasm/analysis; DNA-Binding Proteins/metabolism; Fetus/metabolism; Gene Expression; Histone-Lysine N-Methyltransferase; Humans; Molecular Sequence Data; Myeloid-Lymphoid Leukemia Protein; RNA, Messenger/metabolism; Reverse Transcriptase Polymerase Chain Reaction; Sequence Homology, Amino Acid; Zinc Fingers/genetics

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Database: MEDLINE Main subject: Transcription Factors / Chromosomes, Human, Pair 7 / Proto-Oncogenes / Leukemia / DNA-Binding Proteins / Neoplasm Proteins Type of study: Prognostic_studies / Risk_factors_studies Language: En Journal: Cancer Detect Prev Year: 2001 Type: Article

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