Hematopoietic Cell Growth Factors/therapeutic use; Myeloid Cells/drug effects; Sepsis/drug therapy; Adult; Animals; Animals, Newborn; Chemotaxis, Leukocyte/drug effects; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Cohort Studies; Cross Infection/drug therapy; Cross Infection/epidemiology; Disease Susceptibility; Double-Blind Method; Drug Evaluation, Preclinical; Female; Granulocyte Colony-Stimulating Factor/biosynthesis; Granulocyte Colony-Stimulating Factor/genetics; Granulocyte Colony-Stimulating Factor/pharmacology; Granulocyte Colony-Stimulating Factor/therapeutic use; Granulocyte-Macrophage Colony-Stimulating Factor/biosynthesis; Granulocyte-Macrophage Colony-Stimulating Factor/genetics; Granulocyte-Macrophage Colony-Stimulating Factor/pharmacology; Granulocyte-Macrophage Colony-Stimulating Factor/therapeutic use; Hematopoiesis/drug effects; Hematopoiesis/physiology; Hematopoietic Cell Growth Factors/biosynthesis; Hematopoietic Cell Growth Factors/genetics; Hematopoietic Cell Growth Factors/pharmacology; Humans; Immunocompetence/drug effects; Incidence; Infant; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Interleukins/pharmacology; Interleukins/therapeutic use; Macrophage Colony-Stimulating Factor/biosynthesis; Macrophage Colony-Stimulating Factor/genetics; Macrophage Colony-Stimulating Factor/pharmacology; Macrophage Colony-Stimulating Factor/therapeutic use; Male; Mice; Myeloid Cells/cytology; Neutrophils/drug effects; Phagocytosis/drug effects; Pregnancy; Pregnancy Complications, Infectious; Randomized Controlled Trials as Topic; Rats; Recombinant Proteins/therapeutic use; Respiratory Burst/drug effects