A new synthesis of galactose-poly(ethylene glycol)-polyethylenimine for gene delivery to hepatocytes.

Sagara, Kazuyoshi; Kim, Sung Wan

Sagara, Kazuyoshi; Kim, Sung Wan.

Affiliation

Sagara K; Center for Controlled Chemical Delivery, Department of Pharmaceutics and Pharmaceutical Chemistry, University of Utah, 30 South 2000 East Rm 205, Salt Lake City, UT 84112-5820, USA.

J Control Release ; 79(1-3): 271-81, 2002 Feb 19.

Article in En | MEDLINE | ID: mdl-11853937

Subject(s)

Drug Delivery Systems/methods; Galactose/chemical synthesis; Hepatocytes/drug effects; Polyethylene Glycols/chemical synthesis; Polyethyleneimine/chemical synthesis; 3T3 Cells; Animals; Drug Evaluation, Preclinical; Galactose/administration & dosage; Genetic Therapy/methods; Humans; Mice; Nuclear Magnetic Resonance, Biomolecular; Polyethylene Glycols/pharmacology; Polyethyleneimine/pharmacology; Solvents/chemical synthesis; Solvents/pharmacology; Transfection/methods; Tumor Cells, Cultured

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Database: MEDLINE Main subject: Polyethylene Glycols / Polyethyleneimine / Drug Delivery Systems / Hepatocytes / Galactose Language: En Journal: J Control Release Year: 2002 Type: Article Affiliation country: United States

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