Formulation and in vivo evaluation of chlorhexidine buccal tablets prepared using drug-loaded chitosan microspheres.

Giunchedi, Paolo; Juliano, Claudia; Gavini, Elisabetta; Cossu, Massimo; Sorrenti, Milena

Giunchedi, Paolo; Juliano, Claudia; Gavini, Elisabetta; Cossu, Massimo; Sorrenti, Milena.

Affiliation

Giunchedi P; Dipartimento di Scienze del Farmaco, Università degli Studi di Sassari, Sassari, Italy. pgiunc@ssmain.uniss.it

Eur J Pharm Biopharm ; 53(2): 233-9, 2002 Mar.

Article in En | MEDLINE | ID: mdl-11880008

Subject(s)

Anti-Infective Agents, Local/pharmacokinetics; Chitin/pharmacokinetics; Chlorhexidine/pharmacokinetics; Drug Delivery Systems/methods; Administration, Buccal; Anti-Infective Agents, Local/administration & dosage; Anti-Infective Agents, Local/chemistry; Biocompatible Materials/administration & dosage; Biocompatible Materials/chemistry; Biocompatible Materials/pharmacokinetics; Chemistry, Pharmaceutical; Chitin/administration & dosage; Chitin/analogs & derivatives; Chitin/chemistry; Chitin/ultrastructure; Chitosan; Chlorhexidine/administration & dosage; Chlorhexidine/chemistry; Drug Evaluation, Preclinical/methods; Humans; Microbial Sensitivity Tests/methods; Microbial Sensitivity Tests/statistics & numerical data; Microscopy, Electron, Scanning; Microspheres; Tablets

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Database: MEDLINE Main subject: Chitin / Chlorhexidine / Drug Delivery Systems / Anti-Infective Agents, Local Language: En Journal: Eur J Pharm Biopharm Year: 2002 Type: Article Affiliation country: Italy

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