Selective behavioral and neurochemical effects of cholinergic lesions produced by intrabasalis infusions of 192 IgG-saporin on attentional performance in a five-choice serial reaction time task.

McGaughy, J; Dalley, J W; Morrison, C H; Everitt, B J; Robbins, T W

McGaughy, J; Dalley, J W; Morrison, C H; Everitt, B J; Robbins, T W.

Affiliation

McGaughy J; Department of Experimental Psychology, University of Cambridge, Cambridge CB2 3EB, United Kingdom. drjillmc@bu.edu

J Neurosci ; 22(5): 1905-13, 2002 Mar 01.

Article in En | MEDLINE | ID: mdl-11880520

Subject(s)

Antibodies, Monoclonal/administration & dosage; Attention/drug effects; Basal Nucleus of Meynert/drug effects; Choice Behavior/drug effects; Immunotoxins/administration & dosage; Reaction Time/drug effects; Acetylcholine/metabolism; Animals; Attention/physiology; Basal Nucleus of Meynert/physiology; Behavior, Animal/drug effects; Behavior, Animal/physiology; Cell Count; Choice Behavior/physiology; Choline O-Acetyltransferase/biosynthesis; Drug Administration Routes; Frontal Lobe/metabolism; Male; Microdialysis; N-Glycosyl Hydrolases; Neurons/cytology; Neurons/metabolism; Rats; Rats, Inbred Strains; Ribosome Inactivating Proteins, Type 1; Saporins

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Full text: 1 Database: MEDLINE Main subject: Reaction Time / Attention / Choice Behavior / Immunotoxins / Basal Nucleus of Meynert / Antibodies, Monoclonal Language: En Journal: J Neurosci Year: 2002 Type: Article Affiliation country: United kingdom

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