Green coffee bean extract and its metabolites have a hypotensive effect in spontaneously hypertensive rats.

Suzuki, Atsushi; Kagawa, Daiji; Ochiai, Ryuji; Tokimitsu, Ichiro; Saito, Ikuo

Suzuki, Atsushi; Kagawa, Daiji; Ochiai, Ryuji; Tokimitsu, Ichiro; Saito, Ikuo.

Affiliation

Suzuki A; Biological Science Laboratories, Kao Corp., Tochigi, Japan.

Hypertens Res ; 25(1): 99-107, 2002 Jan.

Article in En | MEDLINE | ID: mdl-11924733

Subject(s)

Antihypertensive Agents/pharmacology; Caffeic Acids/pharmacology; Coffee/chemistry; Coumaric Acids/pharmacology; Hypertension/physiopathology; Plant Extracts/pharmacology; Quinic Acid/analogs & derivatives; Quinic Acid/pharmacology; Rats, Inbred SHR/physiology; Administration, Oral; Animals; Atropine/pharmacology; Blood Pressure/drug effects; Carotid Arteries/drug effects; Carotid Arteries/physiology; Coumaric Acids/antagonists & inhibitors; Injections, Intravenous; Injections, Subcutaneous; Male; Muscarinic Antagonists/pharmacology; Rats; Rats, Inbred WKY; Time Factors

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Database: MEDLINE Main subject: Quinic Acid / Rats, Inbred SHR / Caffeic Acids / Plant Extracts / Coffee / Coumaric Acids / Hypertension / Antihypertensive Agents Language: En Journal: Hypertens Res Year: 2002 Type: Article Affiliation country: Japan

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