PTP1B regulates leptin signal transduction in vivo.

Zabolotny, Janice M; Bence-Hanulec, Kendra K; Stricker-Krongrad, Alain; Haj, Fawaz; Wang, Yongping; Minokoshi, Yasuhiko; Kim, Young-Bum; Elmquist, Joel K; Tartaglia, Louis A; Kahn, Barbara B; Neel, Benjamin G

Zabolotny, Janice M; Bence-Hanulec, Kendra K; Stricker-Krongrad, Alain; Haj, Fawaz; Wang, Yongping; Minokoshi, Yasuhiko; Kim, Young-Bum; Elmquist, Joel K; Tartaglia, Louis A; Kahn, Barbara B; Neel, Benjamin G.

Affiliation

Zabolotny JM; Division of Endocrinology and Metabolism, Division of Hematology and Oncology, Department of Medicine, Boston, MA, USA.

Dev Cell ; 2(4): 489-95, 2002 Apr.

Article in En | MEDLINE | ID: mdl-11970898

Subject(s)

Leptin/metabolism; Obesity/metabolism; Protein Tyrosine Phosphatases/metabolism; Proto-Oncogene Proteins; Signal Transduction/physiology; Animals; COS Cells; Gene Expression Regulation, Enzymologic; Hippocampus/physiology; Hypothalamus/physiology; Janus Kinase 2; Mice; Mice, Knockout; Molecular Sequence Data; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases/genetics; Protein-Tyrosine Kinases/metabolism; Transfection; Weight Gain

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Database: MEDLINE Main subject: Signal Transduction / Proto-Oncogene Proteins / Protein Tyrosine Phosphatases / Leptin / Obesity Language: En Journal: Dev Cell Year: 2002 Type: Article Affiliation country: United States

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