Pharmacokinetics of paclitaxel administered by hyperthermic retrograde isolated lung perfusion techniques.

Schrump, David S; Zhai, Suoping; Nguyen, Dao M; Weiser, Todd S; Fisher, Bradley A; Terrill, Richard E; Flynn, Bernard M; Duray, Paul H; Figg, William D

Schrump, David S; Zhai, Suoping; Nguyen, Dao M; Weiser, Todd S; Fisher, Bradley A; Terrill, Richard E; Flynn, Bernard M; Duray, Paul H; Figg, William D.

Affiliation

Schrump DS; Thoracic Oncology Section, Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892-1502, USA. David_Schrump@nih.gov

J Thorac Cardiovasc Surg ; 123(4): 686-94, 2002 Apr.

Article in En | MEDLINE | ID: mdl-11986596

Subject(s)

Antineoplastic Agents, Phytogenic/administration & dosage; Antineoplastic Agents, Phytogenic/pharmacokinetics; Chemotherapy, Cancer, Regional Perfusion; Lung Neoplasms/drug therapy; Paclitaxel/administration & dosage; Paclitaxel/pharmacokinetics; Animals; Antineoplastic Agents, Phytogenic/blood; Area Under Curve; Bronchi/cytology; Disease Models, Animal; Dose-Response Relationship, Drug; Epithelial Cells/drug effects; Humans; Hyperthermia, Induced/adverse effects; Infusions, Intravenous; Lung Neoplasms/blood; Paclitaxel/blood; Sheep; Treatment Outcome; Tumor Cells, Cultured/drug effects

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Database: MEDLINE Main subject: Chemotherapy, Cancer, Regional Perfusion / Paclitaxel / Lung Neoplasms / Antineoplastic Agents, Phytogenic Type of study: Evaluation_studies / Prognostic_studies Language: En Journal: J Thorac Cardiovasc Surg Year: 2002 Type: Article Affiliation country: United States

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